!Series_title	"Effects of morphine exposure on the transcriptome of the dorsalmedial prefrontal cortex (dmPFC) in rats"
!Series_geo_accession	"GSE233922"
!Series_status	"Public on Jun 06 2023"
!Series_submission_date	"Jun 01 2023"
!Series_last_update_date	"Sep 05 2023"
!Series_pubmed_id	"33626484"
!Series_summary	"We investigated changes in gene transcription induced by subcutanuous morphine injection in adult male and female rats' dmPFC."
!Series_overall_design	"Comparative gene expression profiling analysis of dmPFC RNA-seq data for rats receiving morphine vs. saline injection."
!Series_type	"Expression profiling by high throughput sequencing"
!Series_contributor	"Shirelle,X,Liu"
!Series_contributor	"Mari,S,Gades"
!Series_contributor	"Yayi,,Swain"
!Series_contributor	"Aarthi,,Ramakrishnan"
!Series_contributor	"Andrew,C,Harris"
!Series_contributor	"Phu,V,Tran"
!Series_contributor	"Jonathan,C,Gewirtz"
!Series_sample_id	"GSM7439114 GSM7439115 GSM7439116 GSM7439117 GSM7439118 GSM7439119 GSM7439120 GSM7439121 GSM7439122 GSM7439123 GSM7439124 GSM7439125 "
!Series_contact_name	"Shirelle,Xinyue,Liu"
!Series_contact_institute	"University of Minnesota"
!Series_contact_address	"75 E River Rd"
!Series_contact_city	"Minneapolis"
!Series_contact_state	"Minnesota"
!Series_contact_zip/postal_code	"55455"
!Series_contact_country	"USA"
!Series_supplementary_file	"ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE233nnn/GSE233922/suppl/GSE233922_Gewirtz_004_subread.txt.gz"
!Series_platform_id	"GPL18694"
!Series_platform_taxid	"10116"
!Series_sample_taxid	"10116"
!Series_relation	"BioProject: https://www.ncbi.nlm.nih.gov/bioproject/PRJNA978587"

!Sample_title	"Female, morphine [F1.PFC.MOR]"	"Female, morphine [F2.PFC.MOR]"	"Female, morphine [F3.PFC.MOR]"	"Female, saline [F4.PFC.SAL]"	"Female, saline [F5.PFC.SAL]"	"Female, saline [F6.PFC.SAL]"	"Male, morphine [M1.PFC.MOR]"	"Male, morphine [M2.PFC.MOR]"	"Male, morphine [M3.PFC.MOR]"	"Male, saline [M4.PFC.SAL]"	"Male, saline [M5.PFC.SAL]"	"Male, saline [M6.PFC.SAL]"
!Sample_geo_accession	"GSM7439114"	"GSM7439115"	"GSM7439116"	"GSM7439117"	"GSM7439118"	"GSM7439119"	"GSM7439120"	"GSM7439121"	"GSM7439122"	"GSM7439123"	"GSM7439124"	"GSM7439125"
!Sample_status	"Public on Jun 06 2023"	"Public on Jun 06 2023"	"Public on Jun 06 2023"	"Public on Jun 06 2023"	"Public on Jun 06 2023"	"Public on Jun 06 2023"	"Public on Jun 06 2023"	"Public on Jun 06 2023"	"Public on Jun 06 2023"	"Public on Jun 06 2023"	"Public on Jun 06 2023"	"Public on Jun 06 2023"
!Sample_submission_date	"Jun 01 2023"	"Jun 01 2023"	"Jun 01 2023"	"Jun 01 2023"	"Jun 01 2023"	"Jun 01 2023"	"Jun 01 2023"	"Jun 01 2023"	"Jun 01 2023"	"Jun 01 2023"	"Jun 01 2023"	"Jun 01 2023"
!Sample_last_update_date	"Jun 06 2023"	"Jun 06 2023"	"Jun 06 2023"	"Jun 06 2023"	"Jun 06 2023"	"Jun 06 2023"	"Jun 06 2023"	"Jun 06 2023"	"Jun 06 2023"	"Jun 06 2023"	"Jun 06 2023"	"Jun 06 2023"
!Sample_type	"SRA"	"SRA"	"SRA"	"SRA"	"SRA"	"SRA"	"SRA"	"SRA"	"SRA"	"SRA"	"SRA"	"SRA"
!Sample_channel_count	"1"	"1"	"1"	"1"	"1"	"1"	"1"	"1"	"1"	"1"	"1"	"1"
!Sample_source_name_ch1	"dorsalmedial prefrontal cortex (dmPFC)"	"dorsalmedial prefrontal cortex (dmPFC)"	"dorsalmedial prefrontal cortex (dmPFC)"	"dorsalmedial prefrontal cortex (dmPFC)"	"dorsalmedial prefrontal cortex (dmPFC)"	"dorsalmedial prefrontal cortex (dmPFC)"	"dorsalmedial prefrontal cortex (dmPFC)"	"dorsalmedial prefrontal cortex (dmPFC)"	"dorsalmedial prefrontal cortex (dmPFC)"	"dorsalmedial prefrontal cortex (dmPFC)"	"dorsalmedial prefrontal cortex (dmPFC)"	"dorsalmedial prefrontal cortex (dmPFC)"
!Sample_organism_ch1	"Rattus norvegicus"	"Rattus norvegicus"	"Rattus norvegicus"	"Rattus norvegicus"	"Rattus norvegicus"	"Rattus norvegicus"	"Rattus norvegicus"	"Rattus norvegicus"	"Rattus norvegicus"	"Rattus norvegicus"	"Rattus norvegicus"	"Rattus norvegicus"
!Sample_characteristics_ch1	"tissue: dorsalmedial prefrontal cortex (dmPFC)"	"tissue: dorsalmedial prefrontal cortex (dmPFC)"	"tissue: dorsalmedial prefrontal cortex (dmPFC)"	"tissue: dorsalmedial prefrontal cortex (dmPFC)"	"tissue: dorsalmedial prefrontal cortex (dmPFC)"	"tissue: dorsalmedial prefrontal cortex (dmPFC)"	"tissue: dorsalmedial prefrontal cortex (dmPFC)"	"tissue: dorsalmedial prefrontal cortex (dmPFC)"	"tissue: dorsalmedial prefrontal cortex (dmPFC)"	"tissue: dorsalmedial prefrontal cortex (dmPFC)"	"tissue: dorsalmedial prefrontal cortex (dmPFC)"	"tissue: dorsalmedial prefrontal cortex (dmPFC)"
!Sample_characteristics_ch1	"Sex: Female"	"Sex: Female"	"Sex: Female"	"Sex: Female"	"Sex: Female"	"Sex: Female"	"Sex: Male"	"Sex: Male"	"Sex: Male"	"Sex: Male"	"Sex: Male"	"Sex: Male"
!Sample_characteristics_ch1	"treatment: Morphine"	"treatment: Morphine"	"treatment: Morphine"	"treatment: Saline"	"treatment: Saline"	"treatment: Saline"	"treatment: Morphine"	"treatment: Morphine"	"treatment: Morphine"	"treatment: Saline"	"treatment: Saline"	"treatment: Saline"
!Sample_treatment_protocol_ch1	"Experimetntal group received daily subcutanuoue morphine injection (5.0 mg/kg, 10 days); control group received saline injection. dmPFC was extracted 24 hours after the final injection."	"Experimetntal group received daily subcutanuoue morphine injection (5.0 mg/kg, 10 days); control group received saline injection. dmPFC was extracted 24 hours after the final injection."	"Experimetntal group received daily subcutanuoue morphine injection (5.0 mg/kg, 10 days); control group received saline injection. dmPFC was extracted 24 hours after the final injection."	"Experimetntal group received daily subcutanuoue morphine injection (5.0 mg/kg, 10 days); control group received saline injection. dmPFC was extracted 24 hours after the final injection."	"Experimetntal group received daily subcutanuoue morphine injection (5.0 mg/kg, 10 days); control group received saline injection. dmPFC was extracted 24 hours after the final injection."	"Experimetntal group received daily subcutanuoue morphine injection (5.0 mg/kg, 10 days); control group received saline injection. dmPFC was extracted 24 hours after the final injection."	"Experimetntal group received daily subcutanuoue morphine injection (5.0 mg/kg, 10 days); control group received saline injection. dmPFC was extracted 24 hours after the final injection."	"Experimetntal group received daily subcutanuoue morphine injection (5.0 mg/kg, 10 days); control group received saline injection. dmPFC was extracted 24 hours after the final injection."	"Experimetntal group received daily subcutanuoue morphine injection (5.0 mg/kg, 10 days); control group received saline injection. dmPFC was extracted 24 hours after the final injection."	"Experimetntal group received daily subcutanuoue morphine injection (5.0 mg/kg, 10 days); control group received saline injection. dmPFC was extracted 24 hours after the final injection."	"Experimetntal group received daily subcutanuoue morphine injection (5.0 mg/kg, 10 days); control group received saline injection. dmPFC was extracted 24 hours after the final injection."	"Experimetntal group received daily subcutanuoue morphine injection (5.0 mg/kg, 10 days); control group received saline injection. dmPFC was extracted 24 hours after the final injection."
!Sample_molecule_ch1	"total RNA"	"total RNA"	"total RNA"	"total RNA"	"total RNA"	"total RNA"	"total RNA"	"total RNA"	"total RNA"	"total RNA"	"total RNA"	"total RNA"
!Sample_extract_protocol_ch1	"Samples within each condition for each sex were randomly pooled in groups of three prior to RNA preparation. RNA was extractd using RNeasy Mini Kit (Qiagen). Isolated RNA was further purified and concentrated using the MinElute Cleanup Kit (Qiagen)."	"Samples within each condition for each sex were randomly pooled in groups of three prior to RNA preparation. RNA was extractd using RNeasy Mini Kit (Qiagen). Isolated RNA was further purified and concentrated using the MinElute Cleanup Kit (Qiagen)."	"Samples within each condition for each sex were randomly pooled in groups of three prior to RNA preparation. RNA was extractd using RNeasy Mini Kit (Qiagen). Isolated RNA was further purified and concentrated using the MinElute Cleanup Kit (Qiagen)."	"Samples within each condition for each sex were randomly pooled in groups of three prior to RNA preparation. RNA was extractd using RNeasy Mini Kit (Qiagen). Isolated RNA was further purified and concentrated using the MinElute Cleanup Kit (Qiagen)."	"Samples within each condition for each sex were randomly pooled in groups of three prior to RNA preparation. RNA was extractd using RNeasy Mini Kit (Qiagen). Isolated RNA was further purified and concentrated using the MinElute Cleanup Kit (Qiagen)."	"Samples within each condition for each sex were randomly pooled in groups of three prior to RNA preparation. RNA was extractd using RNeasy Mini Kit (Qiagen). Isolated RNA was further purified and concentrated using the MinElute Cleanup Kit (Qiagen)."	"Samples within each condition for each sex were randomly pooled in groups of three prior to RNA preparation. RNA was extractd using RNeasy Mini Kit (Qiagen). Isolated RNA was further purified and concentrated using the MinElute Cleanup Kit (Qiagen)."	"Samples within each condition for each sex were randomly pooled in groups of three prior to RNA preparation. RNA was extractd using RNeasy Mini Kit (Qiagen). Isolated RNA was further purified and concentrated using the MinElute Cleanup Kit (Qiagen)."	"Samples within each condition for each sex were randomly pooled in groups of three prior to RNA preparation. RNA was extractd using RNeasy Mini Kit (Qiagen). Isolated RNA was further purified and concentrated using the MinElute Cleanup Kit (Qiagen)."	"Samples within each condition for each sex were randomly pooled in groups of three prior to RNA preparation. RNA was extractd using RNeasy Mini Kit (Qiagen). Isolated RNA was further purified and concentrated using the MinElute Cleanup Kit (Qiagen)."	"Samples within each condition for each sex were randomly pooled in groups of three prior to RNA preparation. RNA was extractd using RNeasy Mini Kit (Qiagen). Isolated RNA was further purified and concentrated using the MinElute Cleanup Kit (Qiagen)."	"Samples within each condition for each sex were randomly pooled in groups of three prior to RNA preparation. RNA was extractd using RNeasy Mini Kit (Qiagen). Isolated RNA was further purified and concentrated using the MinElute Cleanup Kit (Qiagen)."
!Sample_extract_protocol_ch1	"RNA was quantified using the RiboGreen RNA Assay kit (Invitrogen) and assessed for quality using capillary electrophoresis (Agilent BioAnalyzer 2100; Agilent). Barcoded libraries were constructed for each sample using the TruSeq RNA v2 kit (Illumina). Libraries were size- (200 bp) selected and sequenced (50bp paired-end read, ~20 million reads/library) using Illumina HiSeq 2500."	"RNA was quantified using the RiboGreen RNA Assay kit (Invitrogen) and assessed for quality using capillary electrophoresis (Agilent BioAnalyzer 2100; Agilent). Barcoded libraries were constructed for each sample using the TruSeq RNA v2 kit (Illumina). Libraries were size- (200 bp) selected and sequenced (50bp paired-end read, ~20 million reads/library) using Illumina HiSeq 2500."	"RNA was quantified using the RiboGreen RNA Assay kit (Invitrogen) and assessed for quality using capillary electrophoresis (Agilent BioAnalyzer 2100; Agilent). Barcoded libraries were constructed for each sample using the TruSeq RNA v2 kit (Illumina). Libraries were size- (200 bp) selected and sequenced (50bp paired-end read, ~20 million reads/library) using Illumina HiSeq 2500."	"RNA was quantified using the RiboGreen RNA Assay kit (Invitrogen) and assessed for quality using capillary electrophoresis (Agilent BioAnalyzer 2100; Agilent). Barcoded libraries were constructed for each sample using the TruSeq RNA v2 kit (Illumina). Libraries were size- (200 bp) selected and sequenced (50bp paired-end read, ~20 million reads/library) using Illumina HiSeq 2500."	"RNA was quantified using the RiboGreen RNA Assay kit (Invitrogen) and assessed for quality using capillary electrophoresis (Agilent BioAnalyzer 2100; Agilent). Barcoded libraries were constructed for each sample using the TruSeq RNA v2 kit (Illumina). Libraries were size- (200 bp) selected and sequenced (50bp paired-end read, ~20 million reads/library) using Illumina HiSeq 2500."	"RNA was quantified using the RiboGreen RNA Assay kit (Invitrogen) and assessed for quality using capillary electrophoresis (Agilent BioAnalyzer 2100; Agilent). Barcoded libraries were constructed for each sample using the TruSeq RNA v2 kit (Illumina). Libraries were size- (200 bp) selected and sequenced (50bp paired-end read, ~20 million reads/library) using Illumina HiSeq 2500."	"RNA was quantified using the RiboGreen RNA Assay kit (Invitrogen) and assessed for quality using capillary electrophoresis (Agilent BioAnalyzer 2100; Agilent). Barcoded libraries were constructed for each sample using the TruSeq RNA v2 kit (Illumina). Libraries were size- (200 bp) selected and sequenced (50bp paired-end read, ~20 million reads/library) using Illumina HiSeq 2500."	"RNA was quantified using the RiboGreen RNA Assay kit (Invitrogen) and assessed for quality using capillary electrophoresis (Agilent BioAnalyzer 2100; Agilent). Barcoded libraries were constructed for each sample using the TruSeq RNA v2 kit (Illumina). Libraries were size- (200 bp) selected and sequenced (50bp paired-end read, ~20 million reads/library) using Illumina HiSeq 2500."	"RNA was quantified using the RiboGreen RNA Assay kit (Invitrogen) and assessed for quality using capillary electrophoresis (Agilent BioAnalyzer 2100; Agilent). Barcoded libraries were constructed for each sample using the TruSeq RNA v2 kit (Illumina). Libraries were size- (200 bp) selected and sequenced (50bp paired-end read, ~20 million reads/library) using Illumina HiSeq 2500."	"RNA was quantified using the RiboGreen RNA Assay kit (Invitrogen) and assessed for quality using capillary electrophoresis (Agilent BioAnalyzer 2100; Agilent). Barcoded libraries were constructed for each sample using the TruSeq RNA v2 kit (Illumina). Libraries were size- (200 bp) selected and sequenced (50bp paired-end read, ~20 million reads/library) using Illumina HiSeq 2500."	"RNA was quantified using the RiboGreen RNA Assay kit (Invitrogen) and assessed for quality using capillary electrophoresis (Agilent BioAnalyzer 2100; Agilent). Barcoded libraries were constructed for each sample using the TruSeq RNA v2 kit (Illumina). Libraries were size- (200 bp) selected and sequenced (50bp paired-end read, ~20 million reads/library) using Illumina HiSeq 2500."	"RNA was quantified using the RiboGreen RNA Assay kit (Invitrogen) and assessed for quality using capillary electrophoresis (Agilent BioAnalyzer 2100; Agilent). Barcoded libraries were constructed for each sample using the TruSeq RNA v2 kit (Illumina). Libraries were size- (200 bp) selected and sequenced (50bp paired-end read, ~20 million reads/library) using Illumina HiSeq 2500."
!Sample_taxid_ch1	"10116"	"10116"	"10116"	"10116"	"10116"	"10116"	"10116"	"10116"	"10116"	"10116"	"10116"	"10116"
!Sample_data_processing	"Quality control on raw sequence data was performed with FastQC."	"Quality control on raw sequence data was performed with FastQC."	"Quality control on raw sequence data was performed with FastQC."	"Quality control on raw sequence data was performed with FastQC."	"Quality control on raw sequence data was performed with FastQC."	"Quality control on raw sequence data was performed with FastQC."	"Quality control on raw sequence data was performed with FastQC."	"Quality control on raw sequence data was performed with FastQC."	"Quality control on raw sequence data was performed with FastQC."	"Quality control on raw sequence data was performed with FastQC."	"Quality control on raw sequence data was performed with FastQC."	"Quality control on raw sequence data was performed with FastQC."
!Sample_data_processing	"Mapping of reads was performed via Hisat2 (version 2.1.0) using the rat genome (rn6) as reference."	"Mapping of reads was performed via Hisat2 (version 2.1.0) using the rat genome (rn6) as reference."	"Mapping of reads was performed via Hisat2 (version 2.1.0) using the rat genome (rn6) as reference."	"Mapping of reads was performed via Hisat2 (version 2.1.0) using the rat genome (rn6) as reference."	"Mapping of reads was performed via Hisat2 (version 2.1.0) using the rat genome (rn6) as reference."	"Mapping of reads was performed via Hisat2 (version 2.1.0) using the rat genome (rn6) as reference."	"Mapping of reads was performed via Hisat2 (version 2.1.0) using the rat genome (rn6) as reference."	"Mapping of reads was performed via Hisat2 (version 2.1.0) using the rat genome (rn6) as reference."	"Mapping of reads was performed via Hisat2 (version 2.1.0) using the rat genome (rn6) as reference."	"Mapping of reads was performed via Hisat2 (version 2.1.0) using the rat genome (rn6) as reference."	"Mapping of reads was performed via Hisat2 (version 2.1.0) using the rat genome (rn6) as reference."	"Mapping of reads was performed via Hisat2 (version 2.1.0) using the rat genome (rn6) as reference."
!Sample_data_processing	"Differentially expressed genes (DEGs) were identified by gene-wise negative binomial generalized linear models using the EdgeR feature in CLC Genomics Workbench p-value (q-value) < 0.05."	"Differentially expressed genes (DEGs) were identified by gene-wise negative binomial generalized linear models using the EdgeR feature in CLC Genomics Workbench p-value (q-value) < 0.05."	"Differentially expressed genes (DEGs) were identified by gene-wise negative binomial generalized linear models using the EdgeR feature in CLC Genomics Workbench p-value (q-value) < 0.05."	"Differentially expressed genes (DEGs) were identified by gene-wise negative binomial generalized linear models using the EdgeR feature in CLC Genomics Workbench p-value (q-value) < 0.05."	"Differentially expressed genes (DEGs) were identified by gene-wise negative binomial generalized linear models using the EdgeR feature in CLC Genomics Workbench p-value (q-value) < 0.05."	"Differentially expressed genes (DEGs) were identified by gene-wise negative binomial generalized linear models using the EdgeR feature in CLC Genomics Workbench p-value (q-value) < 0.05."	"Differentially expressed genes (DEGs) were identified by gene-wise negative binomial generalized linear models using the EdgeR feature in CLC Genomics Workbench p-value (q-value) < 0.05."	"Differentially expressed genes (DEGs) were identified by gene-wise negative binomial generalized linear models using the EdgeR feature in CLC Genomics Workbench p-value (q-value) < 0.05."	"Differentially expressed genes (DEGs) were identified by gene-wise negative binomial generalized linear models using the EdgeR feature in CLC Genomics Workbench p-value (q-value) < 0.05."	"Differentially expressed genes (DEGs) were identified by gene-wise negative binomial generalized linear models using the EdgeR feature in CLC Genomics Workbench p-value (q-value) < 0.05."	"Differentially expressed genes (DEGs) were identified by gene-wise negative binomial generalized linear models using the EdgeR feature in CLC Genomics Workbench p-value (q-value) < 0.05."	"Differentially expressed genes (DEGs) were identified by gene-wise negative binomial generalized linear models using the EdgeR feature in CLC Genomics Workbench p-value (q-value) < 0.05."
!Sample_data_processing	"Feature counts was used for gene quantification"	"Feature counts was used for gene quantification"	"Feature counts was used for gene quantification"	"Feature counts was used for gene quantification"	"Feature counts was used for gene quantification"	"Feature counts was used for gene quantification"	"Feature counts was used for gene quantification"	"Feature counts was used for gene quantification"	"Feature counts was used for gene quantification"	"Feature counts was used for gene quantification"	"Feature counts was used for gene quantification"	"Feature counts was used for gene quantification"
!Sample_data_processing	"Assembly: rn6"	"Assembly: rn6"	"Assembly: rn6"	"Assembly: rn6"	"Assembly: rn6"	"Assembly: rn6"	"Assembly: rn6"	"Assembly: rn6"	"Assembly: rn6"	"Assembly: rn6"	"Assembly: rn6"	"Assembly: rn6"
!Sample_platform_id	"GPL18694"	"GPL18694"	"GPL18694"	"GPL18694"	"GPL18694"	"GPL18694"	"GPL18694"	"GPL18694"	"GPL18694"	"GPL18694"	"GPL18694"	"GPL18694"
!Sample_contact_name	"Shirelle,Xinyue,Liu"	"Shirelle,Xinyue,Liu"	"Shirelle,Xinyue,Liu"	"Shirelle,Xinyue,Liu"	"Shirelle,Xinyue,Liu"	"Shirelle,Xinyue,Liu"	"Shirelle,Xinyue,Liu"	"Shirelle,Xinyue,Liu"	"Shirelle,Xinyue,Liu"	"Shirelle,Xinyue,Liu"	"Shirelle,Xinyue,Liu"	"Shirelle,Xinyue,Liu"
!Sample_contact_institute	"University of Minnesota"	"University of Minnesota"	"University of Minnesota"	"University of Minnesota"	"University of Minnesota"	"University of Minnesota"	"University of Minnesota"	"University of Minnesota"	"University of Minnesota"	"University of Minnesota"	"University of Minnesota"	"University of Minnesota"
!Sample_contact_address	"75 E River Rd"	"75 E River Rd"	"75 E River Rd"	"75 E River Rd"	"75 E River Rd"	"75 E River Rd"	"75 E River Rd"	"75 E River Rd"	"75 E River Rd"	"75 E River Rd"	"75 E River Rd"	"75 E River Rd"
!Sample_contact_city	"Minneapolis"	"Minneapolis"	"Minneapolis"	"Minneapolis"	"Minneapolis"	"Minneapolis"	"Minneapolis"	"Minneapolis"	"Minneapolis"	"Minneapolis"	"Minneapolis"	"Minneapolis"
!Sample_contact_state	"Minnesota"	"Minnesota"	"Minnesota"	"Minnesota"	"Minnesota"	"Minnesota"	"Minnesota"	"Minnesota"	"Minnesota"	"Minnesota"	"Minnesota"	"Minnesota"
!Sample_contact_zip/postal_code	"55455"	"55455"	"55455"	"55455"	"55455"	"55455"	"55455"	"55455"	"55455"	"55455"	"55455"	"55455"
!Sample_contact_country	"USA"	"USA"	"USA"	"USA"	"USA"	"USA"	"USA"	"USA"	"USA"	"USA"	"USA"	"USA"
!Sample_data_row_count	"0"	"0"	"0"	"0"	"0"	"0"	"0"	"0"	"0"	"0"	"0"	"0"
!Sample_instrument_model	"Illumina HiSeq 2500"	"Illumina HiSeq 2500"	"Illumina HiSeq 2500"	"Illumina HiSeq 2500"	"Illumina HiSeq 2500"	"Illumina HiSeq 2500"	"Illumina HiSeq 2500"	"Illumina HiSeq 2500"	"Illumina HiSeq 2500"	"Illumina HiSeq 2500"	"Illumina HiSeq 2500"	"Illumina HiSeq 2500"
!Sample_library_selection	"cDNA"	"cDNA"	"cDNA"	"cDNA"	"cDNA"	"cDNA"	"cDNA"	"cDNA"	"cDNA"	"cDNA"	"cDNA"	"cDNA"
!Sample_library_source	"transcriptomic"	"transcriptomic"	"transcriptomic"	"transcriptomic"	"transcriptomic"	"transcriptomic"	"transcriptomic"	"transcriptomic"	"transcriptomic"	"transcriptomic"	"transcriptomic"	"transcriptomic"
!Sample_library_strategy	"RNA-Seq"	"RNA-Seq"	"RNA-Seq"	"RNA-Seq"	"RNA-Seq"	"RNA-Seq"	"RNA-Seq"	"RNA-Seq"	"RNA-Seq"	"RNA-Seq"	"RNA-Seq"	"RNA-Seq"
!Sample_relation	"BioSample: https://www.ncbi.nlm.nih.gov/biosample/SAMN35557981"	"BioSample: https://www.ncbi.nlm.nih.gov/biosample/SAMN35557980"	"BioSample: https://www.ncbi.nlm.nih.gov/biosample/SAMN35557979"	"BioSample: https://www.ncbi.nlm.nih.gov/biosample/SAMN35557978"	"BioSample: https://www.ncbi.nlm.nih.gov/biosample/SAMN35557977"	"BioSample: https://www.ncbi.nlm.nih.gov/biosample/SAMN35557976"	"BioSample: https://www.ncbi.nlm.nih.gov/biosample/SAMN35557975"	"BioSample: https://www.ncbi.nlm.nih.gov/biosample/SAMN35557974"	"BioSample: https://www.ncbi.nlm.nih.gov/biosample/SAMN35557973"	"BioSample: https://www.ncbi.nlm.nih.gov/biosample/SAMN35557972"	"BioSample: https://www.ncbi.nlm.nih.gov/biosample/SAMN35557971"	"BioSample: https://www.ncbi.nlm.nih.gov/biosample/SAMN35557970"
!Sample_relation	"SRA: https://www.ncbi.nlm.nih.gov/sra?term=SRX20568383"	"SRA: https://www.ncbi.nlm.nih.gov/sra?term=SRX20568384"	"SRA: https://www.ncbi.nlm.nih.gov/sra?term=SRX20568385"	"SRA: https://www.ncbi.nlm.nih.gov/sra?term=SRX20568386"	"SRA: https://www.ncbi.nlm.nih.gov/sra?term=SRX20568387"	"SRA: https://www.ncbi.nlm.nih.gov/sra?term=SRX20568388"	"SRA: https://www.ncbi.nlm.nih.gov/sra?term=SRX20568389"	"SRA: https://www.ncbi.nlm.nih.gov/sra?term=SRX20568390"	"SRA: https://www.ncbi.nlm.nih.gov/sra?term=SRX20568391"	"SRA: https://www.ncbi.nlm.nih.gov/sra?term=SRX20568392"	"SRA: https://www.ncbi.nlm.nih.gov/sra?term=SRX20568393"	"SRA: https://www.ncbi.nlm.nih.gov/sra?term=SRX20568394"
!Sample_supplementary_file_1	"NONE"	"NONE"	"NONE"	"NONE"	"NONE"	"NONE"	"NONE"	"NONE"	"NONE"	"NONE"	"NONE"	"NONE"
!series_matrix_table_begin
"ID_REF"	"GSM7439114"	"GSM7439115"	"GSM7439116"	"GSM7439117"	"GSM7439118"	"GSM7439119"	"GSM7439120"	"GSM7439121"	"GSM7439122"	"GSM7439123"	"GSM7439124"	"GSM7439125"
!series_matrix_table_end
