Overview of HIV associated Cell line (Mutation)

ID Literature Title Group
1 10620603 The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore
Mutation
2 11181702 Control of mitochondrial membrane permeabilization by adenine nucleotide translocator interacting with HIV-1 viral protein rR and Bcl-2
Mutation
3 15737233 Phosphorylation of HIV Tat by PKR increases interaction with TAR RNA and enhances transcription
Mutation
4 16723431 Analysis of HIV-1 replication block due to substitutions at F61 residue of reverse transcriptase reveals additional defects involving the RNase H function
Mutation
5 16870786 Alkoxyalkyl esters of (S)-9-[3-hydroxy-2-(phosphonomethoxy)propyl]adenine are potent inhibitors of the replication of wild-type and drug-resistant human immunodeficiency virus type 1 in vitro
Mutation
6 17005036 Construction of doxycyline-dependent mini-HIV-1 variants for the development of a virotherapy against leukemias
Mutation
7 17083724 Phosphorylation of HIV-1 Tat by CDK2 in HIV-1 transcription
Mutation
8 17087820 Human TRIM5alpha mediated restriction of different HIV-1 subtypes and Lv2 sensitive and insensitive HIV-2 variants
Mutation
9 17134507 Second site escape of a T20-dependent HIV-1 variant by a single amino acid change in the CD4 binding region of the envelope glycoprotein
Mutation
10 17140287 HIV-1 Vpr-induced apoptosis is cell cycle dependent and requires Bax but not ANT
Mutation
11 17176473 PRMT6 diminishes HIV-1 Rev binding to and export of viral RNA
Mutation
12 17225856 Recruitment and activation of RSK2 by HIV-1 Tat
Mutation
13 17227139 A novel substrate-based HIV-1 protease inhibitor drug resistance mechanism
Mutation
14 17371591 Mutation in the loop C-terminal to the cyclophilin A binding site of HIV-1 capsid protein disrupts proper virus assembly and infectivity
Mutation
15 17559673 HIV-1 Vpr activates the G2 checkpoint through manipulation of the ubiquitin proteasome system
Mutation
16 17967060 Evidence for direct involvement of the capsid protein in HIV infection of nondividing cells
Mutation
17 18039376 Localization of HIV-1 Vpr to the nuclear envelope: impact on Vpr functions and virus replication in macrophages
Mutation
18 18237398 The carbohydrate at asparagine 386 on HIV-1 gp120 is not essential for protein folding and function but is involved in immune evasion
Mutation
19 18445273 14-3-3 theta binding to cell cycle regulatory factors is enhanced by HIV-1 Vpr
Mutation
20 18808682 Direct Vpr-Vpr interaction in cells monitored by two photon fluorescence correlation spectroscopy and fluorescence lifetime imaging
Mutation
21 18837996 The V1-V3 region of a brain-derived HIV-1 envelope glycoprotein determines macrophage tropism, low CD4 dependence, increased fusogenicity and altered sensitivity to entry inhibitors
Mutation
22 19300491 Gag mutations strongly contribute to HIV-1 resistance to protease inhibitors in highly drug-experienced patients besides compensating for fitness loss
Mutation
23 20010074 N348I in HIV-1 reverse transcriptase decreases susceptibility to tenofovir and etravirine in combination with other resistance mutations
Mutation
24 21237475 BST-2 is rapidly down-regulated from the cell surface by the HIV-1 protein Vpu: evidence for a post-ER mechanism of Vpu-action
Mutation
25 22333046 The HR2 polymorphism N140I in the HIV-1 gp41 combined with the HR1 V38A mutation is associated with a less cytopathic phenotype
Mutation
26 22651890 Overlapping effector interfaces define the multiple functions of the HIV-1 Nef polyproline helix
Mutation
27 23011758 HIV-1 Env gp120 structural determinants for peptide triazole dual receptor site antagonism
Mutation
28 24415937 In vivo functions of CPSF6 for HIV-1 as revealed by HIV-1 capsid evolution in HLA-B27-positive subjects
Mutation
29 24418540 Defining HIV-1 Vif residues that interact with CBFbeta by site-directed mutagenesis
Mutation
30 24422669 HIV-1 Vif N-terminal motif is required for recruitment of Cul5 to suppress APOBEC3
Mutation
31 24758333 Impact of amino acid substitutions in the V2 and C2 regions of human immunodeficiency virus type 1 CRF01_AE envelope glycoprotein gp120 on viral neutralization susceptibility to broadly neutralizing antibodies specific for the CD4 binding site
Mutation
32 24884783 Differential binding of neutralizing and non-neutralizing antibodies to native-like soluble HIV-1 Env trimers, uncleaved Env proteins, and monomeric subunits
Mutation
33 25144636 Azvudine, a novel nucleoside reverse transcriptase inhibitor showed good drug combination features and better inhibition on drug-resistant strains than lamivudine in vitro
Mutation
34 25174000 A broad HIV-1 inhibitor blocks envelope glycoprotein transitions critical for entry
Mutation
35 25217711 Deletions in the fifth alpha helix of HIV-1 matrix block virus release
Mutation
36 25393958 Function-based mutation-resistant synthetic signaling device activated by HIV-1 proteolysis
Mutation
37 25524645 Re-visiting the functional Relevance of the highly conserved Serine 40 Residue within HIV-1 p6(Gag)
Mutation
38 25849367 Effects of the I559P gp41 change on the conformation and function of the human immunodeficiency virus (HIV-1) membrane envelope glycoprotein trimer
Mutation
39 27130466 Effect on HIV-1 viral replication capacity of DTG-resistance mutations in NRTI/NNRTI resistant viruses
Mutation
40 27181553 CD8 Encephalitis Caused by Persistently Detectable Drug-resistant HIV
Mutation
41 27754450 Single Amino Acid Substitution N659D in HIV-2 Envelope Glycoprotein (Env) Impairs Viral Release and Hampers BST-2 Antagonism
Mutation
42 28100611 The Envelope Gene of Transmitted HIV-1 Resists a Late Interferon Gamma-Induced Block
Mutation
43 29666292 Human Immunodeficiency Virus Tat Protein Aids V Region Somatic Hypermutation in Human B Cells
Mutation
44 29677220 HIV-1 adaptation studies reveal a novel Env-mediated homeostasis mechanism for evading lethal hypermutation by APOBEC3G
Mutation
45 29792216 HIV-1 Tat phosphorylation on Ser-16 residue modulates HIV-1 transcription
Mutation
46 30029500 The HIV-1 Reverse Transcriptase A62V Mutation Influences Replication Fidelity and Viral Fitness in the Context of Multi-Drug-Resistant Mutations
Mutation
47 30327442 Identification of a Structural Element in HIV-1 Gag Required for Virus Particle Assembly and Maturation
Mutation
48 30543749 Structural Adaptation of Darunavir Analogues against Primary Mutations in HIV-1 Protease
Mutation
49 30566493 Guiding the humoral response against HIV-1 toward a MPER adjacent region by immunization with a VLP-formulated antibody-selected envelope variant
Mutation
50 30696772 HIV-1 anchor inhibitors and membrane fusion inhibitors target distinct but overlapping steps in virus entry
Mutation
51 30709739 An Antigenic Atlas of HIV-1 Escape from Broadly Neutralizing Antibodies Distinguishes Functional and Structural Epitopes
Mutation
52 30769947 Induction of Tier 1 HIV Neutralizing Antibodies by Envelope Trimers Incorporated into a Replication Competent Vesicular Stomatitis Virus Vector
Mutation
53 30808702 HIV-1 Escape from Small-Molecule Antagonism of Vif
Mutation
54 30814513 Rationally designed carbohydrate-occluded epitopes elicit HIV-1 Env-specific antibodies
Mutation
55 30824746 A Naturally Occurring Polymorphism in the HIV-1 Tat Basic Domain Inhibits Uptake by Bystander Cells and Leads to Reduced Neuroinflammation
Mutation
56 30862755 Novel Intersubunit Interaction Critical for HIV-1 Core Assembly Defines a Potentially Targetable Inhibitor Binding Pocket
Mutation
57 30914719 Highly Mutable Linker Regions Regulate HIV-1 Rev Function and Stability
Mutation
58 31025011 Role of co-expressed APOBEC3F and APOBEC3G in inducing HIV-1 drug resistance
Mutation
59 31120420 HIV-1 integrase tetramers are the antiviral target of pyridine-based allosteric integrase inhibitors
Mutation
60 31186327 Potent Enhancement of HIV-1 Replication by Nef in the Absence of SERINC3 and SERINC5
Mutation
61 31242909 NNRTI-induced HIV-1 protease-mediated cytotoxicity induces rapid death of CD4 T cells during productive infection and latency reversal
Mutation
62 31266880 Resistance to the Tat Inhibitor Didehydro-Cortistatin A Is Mediated by Heightened Basal HIV-1 Transcription
Mutation
63 31409143 Kinetic and thermodynamic characterisation of HIV-protease inhibitors against E35D upward arrowG upward arrowS mutant in the South African HIV-1 subtype C protease
Mutation
64 31511380 Multiple Pathways To Avoid Beta Interferon Sensitivity of HIV-1 by Mutations in Capsid
Mutation
65 31527908 Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies
Mutation
66 33374603 Extended Interactions between HIV-1 Viral RNA and tRNA(Lys3) Are Important to Maintain Viral RNA Integrity
Mutation
Contents
Description
Disease Group Note
  • The label in Group indicates that the disease is mentioned in mutation or integration research. Click the eye label to view the corresponding module information.