All Curated Mutation Sites in HBV 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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S
  
BCP
  
X
  
C
  
Core Promoter
  
Core Upstream Regulatory Sequence
  
DR1
  
EnhI
  
EnhII
  
PreC
  
P
  
PreC Promoter
  
PreS
  
PreS1
  
PreS1 Promoter
  
PreS2
  
RT
  
S Promoter
  
S1 Promoter
  
S2 Promoter
  
X Promoter
  

Keyword: Hepatitis B, Chronic-16928212
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 16928212 T1753A
Core Promoter
Hepatitis B, Chronic
L
View
2 16928212 C221G
P
P
Hepatitis B, Chronic
L
View
3 16928212 E164D
S
S
Hepatitis B, Chronic
L
View
4 16928212 F219S
S
S
Hepatitis B, Chronic
L
View
5 16928212 F220L
S
S
Hepatitis B, Chronic
L
View
6 16928212 S193L
S
S
Hepatitis B, Chronic
L
View
7 16928212 S207R
S
S
Hepatitis B, Chronic
L
View
8 16928212 T115A
S
S
Hepatitis B, Chronic
L
View
9 16928212 W182X
S
S
Hepatitis B, Chronic
L
View
10 16928212 A80G
C
C
Hepatitis B, Chronic
L
View
11 16928212 G1896A
PreC
C
Hepatitis B, Chronic
L
View
12 16928212 W28X
PreC
C
Hepatitis B, Chronic
L
View
13 16928212 E64D
C
C
Hepatitis B, Chronic
L
View
14 16928212 P130T
C
C
Hepatitis B, Chronic
L
View
15 16928212 T67S
C
C
Hepatitis B, Chronic
L
View
16 16928212 M133T
S
S
Hepatitis B, Chronic
L
View
17 16928212 P127A
S
S
Hepatitis B, Chronic
L
View
18 16928212 P127S
S
S
Hepatitis B, Chronic
L
View
19 16928212 S143L
S
S
Hepatitis B, Chronic
L
View
20 16928212 T1753C
Core Promoter
Hepatitis B, Chronic
L
View
21 16928212 A128V
S
S
Hepatitis B, Chronic
L
View
22 16928212 P120S
S
S
Hepatitis B, Chronic
L
View
23 16928212 G185Q
S
S
Hepatitis B, Chronic
L
View
24 16928212 T118V
S
S
Hepatitis B, Chronic
L
View
25 16928212 A1752T
Core Promoter
Hepatitis B, Chronic
L
View
26 16928212 M204V
RT
P
Hepatitis B, Chronic
D
L
View
27 16928212 I195M
S
S
Hepatitis B, Chronic
L
View
28 16928212 W196X
S
S
Hepatitis B, Chronic
L
View
29 16928212 W196L
S
S
Hepatitis B, Chronic
L
View
30 16928212 C1766G
Core Promoter
Hepatitis B, Chronic
L
View
31 16928212 G1764T
Core Promoter
Hepatitis B, Chronic
L
View
32 16928212 A1762T
Core Promoter
Hepatitis B, Chronic
L
View
33 16928212 G1764A
Core Promoter
Hepatitis B, Chronic
L
View
34 16928212 M204I
RT
P
Hepatitis B, Chronic
D
L
View
Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.