All Curated Mutation Sites in HBV

The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.

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Virus Gene/Protein

Disease

Description

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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BCP

Core Promoter

Core Upstream Regulatory Sequence

Keyword: Hepatitis B, Chronic-17258721

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	17258721	M204I	P	P	Hepatitis B, Chronic	G R C	View
2	17258721	L180M	RT	P	Hepatitis B, Chronic	G R C	View
3	17258721	M204V	RT	P	Hepatitis B, Chronic	G R C	View
4	17258721	P120A	S	S	Hepatitis B, Chronic	G R C	View
5	17258721	A136G	PreS1	S	Hepatitis B, Chronic	G R C	View
6	17258721	A166G	PreS1	S	Hepatitis B, Chronic	G R C	View
7	17258721	A167G	PreS1	S	Hepatitis B, Chronic	G R C	View
8	17258721	A167T	PreS1	S	Hepatitis B, Chronic	G R C	View
9	17258721	A62S	PreS1	S	Hepatitis B, Chronic	G R C	View
10	17258721	C121X	S	S	Hepatitis B, Chronic	G R C	View
11	17258721	C157G	PreS1	S	Hepatitis B, Chronic	G R C	View
12	17258721	C158G	PreS1	S	Hepatitis B, Chronic	G R C	View
13	17258721	C193G	PreS1	S	Hepatitis B, Chronic	G R C	View
14	17258721	C27A	PreS2	S	Hepatitis B, Chronic	G R C	View
15	17258721	C358G	S	S	Hepatitis B, Chronic	G R C	View
16	17258721	C363A	S	S	Hepatitis B, Chronic	G R C	View
17	17258721	C428T	S	S	Hepatitis B, Chronic	G R C	View
18	17258721	C4A	PreS2	S	Hepatitis B, Chronic	G R C	View
19	17258721	D42E	PreS1	S	Hepatitis B, Chronic	G R C	View
20	17258721	F134I	S	S	Hepatitis B, Chronic	G R C	View
21	17258721	F63V	PreS1	S	Hepatitis B, Chronic	G R C	View
22	17258721	G184T	PreS1	S	Hepatitis B, Chronic	G R C	View
23	17258721	G338A	PreS1	S	Hepatitis B, Chronic	G R C	View
24	17258721	G53A	PreS2	S	Hepatitis B, Chronic	G R C	View
25	17258721	H9Q	PreS2	S	Hepatitis B, Chronic	G R C	View
26	17258721	L8R	PreS1	S	Hepatitis B, Chronic	G R C	View
27	17258721	N46D	PreS1	S	Hepatitis B, Chronic	G R C	View
28	17258721	N56D	PreS1	S	Hepatitis B, Chronic	G R C	View
29	17258721	N56I	PreS1	S	Hepatitis B, Chronic	G R C	View
30	17258721	N56S	PreS1	S	Hepatitis B, Chronic	G R C	View
31	17258721	P53A	PreS1	S	Hepatitis B, Chronic	G R C	View
32	17258721	P53R	PreS1	S	Hepatitis B, Chronic	G R C	View
33	17258721	P65A	PreS1	S	Hepatitis B, Chronic	G R C	View
34	17258721	Q2K	PreS2	S	Hepatitis B, Chronic	G R C	View
35	17258721	R113K	PreS1	S	Hepatitis B, Chronic	G R C	View
36	17258721	R18K	PreS2	S	Hepatitis B, Chronic	G R C	View
37	17258721	S29P	PreS2	S	Hepatitis B, Chronic	G R C	View
38	17258721	S85P	PreS2	S	Hepatitis B, Chronic	G R C	View
39	17258721	T126A	PreS1	S	Hepatitis B, Chronic	G R C	View
40	17258721	T127A	PreS1	S	Hepatitis B, Chronic	G R C	View
41	17258721	T143M	S	S	Hepatitis B, Chronic	G R C	View
42	17258721	T187G	PreS1	S	Hepatitis B, Chronic	G R C	View
43	17258721	T23G	PreS1	S	Hepatitis B, Chronic	G R C	View
44	17258721	T400A	S	S	Hepatitis B, Chronic	G R C	View
45	17258721	T85C	PreS2	S	Hepatitis B, Chronic	G R C	View
46	17258721	W43G	PreS1	S	Hepatitis B, Chronic	G R C	View
47	17258721	W43R	PreS1	S	Hepatitis B, Chronic	G R C	View

Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note

D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.

G
The study mentioned the virus genotype/subtype information.

R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.

S
The study provided sequence information or accession numbers.

L
The study provided the geographic region/country of data origin.

C
The study provided clinical baseline information.

I
The study involved information related to immune.

T
The study involved host target genes.