All Curated Mutation Sites in HBV 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

Show All
  
S
  
BCP
  
X
  
C
  
Core Promoter
  
Core Upstream Regulatory Sequence
  
DR1
  
EnhI
  
EnhII
  
PreC
  
P
  
PreC Promoter
  
PreS
  
PreS1
  
PreS1 Promoter
  
PreS2
  
RT
  
S Promoter
  
S1 Promoter
  
S2 Promoter
  
X Promoter
  

Keyword: Hepatitis B, Chronic-21784687
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 21784687 L180M
RT
P
Hepatitis B, Chronic
D
G
C
L
View
2 21784687 L80I
RT
P
Hepatitis B, Chronic
D
G
C
L
View
3 21784687 Q215S
RT
P
Hepatitis B, Chronic
D
G
C
L
View
4 21784687 S202C
RT
P
Hepatitis B, Chronic
D
G
C
L
View
5 21784687 V214P
RT
P
Hepatitis B, Chronic
D
G
C
L
View
6 21784687 A181T
RT
P
Hepatitis B, Chronic
D
G
C
L
View
7 21784687 A181V
RT
P
Hepatitis B, Chronic
D
G
C
L
View
8 21784687 E164D
S
S
Hepatitis B, Chronic
D
G
C
L
View
9 21784687 I195M
S
S
Hepatitis B, Chronic
D
G
C
L
View
10 21784687 L173F
S
S
Hepatitis B, Chronic
D
G
C
L
View
11 21784687 M204I
RT
P
Hepatitis B, Chronic
D
G
C
L
View
12 21784687 M204V
RT
P
Hepatitis B, Chronic
D
G
C
L
View
13 21784687 V173L
RT
P
Hepatitis B, Chronic
D
G
C
L
View
14 21784687 W172X
S
S
Hepatitis B, Chronic
D
G
C
L
View
15 21784687 W172L
S
S
Hepatitis B, Chronic
D
G
C
L
View
16 21784687 W196L
S
S
Hepatitis B, Chronic
D
G
C
L
View
17 21784687 W196S
S
S
Hepatitis B, Chronic
D
G
C
L
View
18 21784687 F161H
S
S
Hepatitis B, Chronic
D
G
C
L
View
19 21784687 F161L
S
S
Hepatitis B, Chronic
D
G
C
L
View
20 21784687 L175F
S
S
Hepatitis B, Chronic
D
G
C
L
View
21 21784687 L176V
S
S
Hepatitis B, Chronic
D
G
C
L
View
22 21784687 S193F
S
S
Hepatitis B, Chronic
D
G
C
L
View
23 21784687 S193L
S
S
Hepatitis B, Chronic
D
G
C
L
View
24 21784687 S194F
S
S
Hepatitis B, Chronic
D
G
C
L
View
25 21784687 S194S
S
S
Hepatitis B, Chronic
D
G
C
L
View
26 21784687 S202G
RT
P
Hepatitis B, Chronic
D
G
C
L
View
27 21784687 T184C
RT
P
Hepatitis B, Chronic
D
G
C
L
View
28 21784687 T184G
RT
P
Hepatitis B, Chronic
D
G
C
L
View
29 21784687 T184L
RT
P
Hepatitis B, Chronic
D
G
C
L
View
30 21784687 T184M
RT
P
Hepatitis B, Chronic
D
G
C
L
View
31 21784687 T184S
RT
P
Hepatitis B, Chronic
D
G
C
L
View
32 21784687 V191I
RT
P
Hepatitis B, Chronic
D
G
C
L
View
33 21784687 W182X
S
S
Hepatitis B, Chronic
D
G
C
L
View
Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.