All Curated Mutation Sites in HBV

The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.

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Virus Gene/Protein

Disease

Description

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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BCP

Core Promoter

Core Upstream Regulatory Sequence

Keyword: Hepatitis B, Chronic-22170539

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	22170539	A181V	RT	P	Hepatitis B, Chronic	D G R S C L	View
2	22170539	L229F	RT	P	Hepatitis B, Chronic	G R S C L	View
3	22170539	L229V	RT	P	Hepatitis B, Chronic	G R S C L	View
4	22170539	I169L	RT	P	Hepatitis B, Chronic	D G R S C L	View
5	22170539	A181T	RT	P	Hepatitis B, Chronic	D G R S C L	View
6	22170539	N139D	RT	P	Hepatitis B, Chronic	G R S C L	View
7	22170539	N139H	RT	P	Hepatitis B, Chronic	G R S C L	View
8	22170539	N139K	RT	P	Hepatitis B, Chronic	G R S C L	View
9	22170539	L80I	RT	P	Hepatitis B, Chronic	D G R S C L	View
10	22170539	L80V	RT	P	Hepatitis B, Chronic	D G R S C L	View
11	22170539	H126Y	RT	P	Hepatitis B, Chronic	G R S C L	View
12	22170539	L82M	RT	P	Hepatitis B, Chronic	G R S C L	View
13	22170539	N139Q	RT	P	Hepatitis B, Chronic	G R S C L	View
14	22170539	T128N	RT	P	Hepatitis B, Chronic	G R S C L	View
15	22170539	T38K	RT	P	Hepatitis B, Chronic	G R S C L	View
16	22170539	V191I	RT	P	Hepatitis B, Chronic	G R S C L	View
17	22170539	V214A	RT	P	Hepatitis B, Chronic	G R S C L	View
18	22170539	M204I	RT	P	Hepatitis B, Chronic	D G R S C L	View
19	22170539	M204V	RT	P	Hepatitis B, Chronic	D G R S C L	View
20	22170539	N236T	RT	P	Hepatitis B, Chronic	D G R S C L	View
21	22170539	T184S	RT	P	Hepatitis B, Chronic	D G R S C L	View
22	22170539	C256G	RT	P	Hepatitis B, Chronic	G R S C L	View
23	22170539	E218D	RT	P	Hepatitis B, Chronic	G R S C L	View
24	22170539	I233V	RT	P	Hepatitis B, Chronic	G R S C L	View
25	22170539	N139T	RT	P	Hepatitis B, Chronic	G R S C L	View
26	22170539	R153Q	RT	P	Hepatitis B, Chronic	G R S C L	View
27	22170539	R153W	RT	P	Hepatitis B, Chronic	G R S C L	View
28	22170539	R242K	RT	P	Hepatitis B, Chronic	G R S C L	View
29	22170539	R242S	RT	P	Hepatitis B, Chronic	G R S C L	View
30	22170539	S213T	RT	P	Hepatitis B, Chronic	G R S C L	View
31	22170539	S256G	RT	P	Hepatitis B, Chronic	G R S C L	View
32	22170539	T128A	RT	P	Hepatitis B, Chronic	G R S C L	View
33	22170539	T128I	RT	P	Hepatitis B, Chronic	G R S C L	View
34	22170539	T38A	RT	P	Hepatitis B, Chronic	G R S C L	View
35	22170539	V207M	RT	P	Hepatitis B, Chronic	G R S C L	View
36	22170539	L180M	RT	P	Hepatitis B, Chronic	D G R S C L	View
37	22170539	D134E	RT	P	Hepatitis B, Chronic	G R S C L	View
38	22170539	D134I	RT	P	Hepatitis B, Chronic	G R S C L	View
39	22170539	D134N	RT	P	Hepatitis B, Chronic	G R S C L	View
40	22170539	D134S	RT	P	Hepatitis B, Chronic	G R S C L	View
41	22170539	F221F	RT	P	Hepatitis B, Chronic	G R S C L	View
42	22170539	F221Y	RT	P	Hepatitis B, Chronic	G R S C L	View
43	22170539	H238N	RT	P	Hepatitis B, Chronic	G R S C L	View
44	22170539	H238Q	RT	P	Hepatitis B, Chronic	G R S C L	View
45	22170539	H238S	RT	P	Hepatitis B, Chronic	G R S C L	View
46	22170539	H238T	RT	P	Hepatitis B, Chronic	G R S C L	View
47	22170539	I224V	RT	P	Hepatitis B, Chronic	G R S C L	View
48	22170539	I91L	RT	P	Hepatitis B, Chronic	G R S C L	View
49	22170539	L91I	RT	P	Hepatitis B, Chronic	G R S C L	View
50	22170539	N124D	RT	P	Hepatitis B, Chronic	G R S C L	View
51	22170539	N124H	RT	P	Hepatitis B, Chronic	G R S C L	View
52	22170539	N124N	RT	P	Hepatitis B, Chronic	G R S C L	View
53	22170539	N124Y	RT	P	Hepatitis B, Chronic	G R S C L	View
54	22170539	N134D	RT	P	Hepatitis B, Chronic	G R S C L	View
55	22170539	N134E	RT	P	Hepatitis B, Chronic	G R S C L	View
56	22170539	N134I	RT	P	Hepatitis B, Chronic	G R S C L	View
57	22170539	N134N	RT	P	Hepatitis B, Chronic	G R S C L	View
58	22170539	N134S	RT	P	Hepatitis B, Chronic	G R S C L	View
59	22170539	N238H	RT	P	Hepatitis B, Chronic	G R S C L	View
60	22170539	N238N	RT	P	Hepatitis B, Chronic	G R S C L	View
61	22170539	N238Q	RT	P	Hepatitis B, Chronic	G R S C L	View
62	22170539	N238S	RT	P	Hepatitis B, Chronic	G R S C L	View
63	22170539	N238T	RT	P	Hepatitis B, Chronic	G R S C L	View
64	22170539	N53D	RT	P	Hepatitis B, Chronic	G R S C L	View
65	22170539	N53S	RT	P	Hepatitis B, Chronic	G R S C L	View
66	22170539	N53T	RT	P	Hepatitis B, Chronic	G R S C L	View
67	22170539	S53D	RT	P	Hepatitis B, Chronic	G R S C L	View
68	22170539	S53N	RT	P	Hepatitis B, Chronic	G R S C L	View
69	22170539	S53T	RT	P	Hepatitis B, Chronic	G R S C L	View
70	22170539	V224I	RT	P	Hepatitis B, Chronic	G R S C L	View
71	22170539	Y124D	RT	P	Hepatitis B, Chronic	G R S C L	View
72	22170539	Y124H	RT	P	Hepatitis B, Chronic	G R S C L	View
73	22170539	Y124N	RT	P	Hepatitis B, Chronic	G R S C L	View
74	22170539	Y124Y	RT	P	Hepatitis B, Chronic	G R S C L	View
75	22170539	Y221F	RT	P	Hepatitis B, Chronic	G R S C L	View
76	22170539	Y221Y	RT	P	Hepatitis B, Chronic	G R S C L	View

Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note

D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.

G
The study mentioned the virus genotype/subtype information.

R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.

S
The study provided sequence information or accession numbers.

L
The study provided the geographic region/country of data origin.

C
The study provided clinical baseline information.

I
The study involved information related to immune.

T
The study involved host target genes.