All Curated Mutation Sites in HBV 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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S
  
BCP
  
X
  
C
  
Core Promoter
  
Core Upstream Regulatory Sequence
  
DR1
  
EnhI
  
EnhII
  
PreC
  
P
  
PreC Promoter
  
PreS
  
PreS1
  
PreS1 Promoter
  
PreS2
  
RT
  
S Promoter
  
S1 Promoter
  
S2 Promoter
  
X Promoter
  

Keyword: Hepatitis B, Chronic-23710315
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 23710315 M204I
RT
P
Hepatitis B, Chronic
D
G
R
C
View
2 23710315 I169L
P
P
Hepatitis B, Chronic
D
G
R
C
View
3 23710315 N236H
P
P
Hepatitis B, Chronic
D
G
R
C
View
4 23710315 S202G
P
P
Hepatitis B, Chronic
D
G
R
C
View
5 23710315 V84I
P
P
Hepatitis B, Chronic
D
G
R
C
View
6 23710315 M204V
P
P
Hepatitis B, Chronic
D
G
R
C
View
7 23710315 L80I
P
P
Hepatitis B, Chronic
G
R
C
View
8 23710315 L80V
P
P
Hepatitis B, Chronic
G
R
C
View
9 23710315 W153Q
P
P
Hepatitis B, Chronic
G
R
C
View
10 23710315 A181V
P
P
Hepatitis B, Chronic
D
G
R
C
View
11 23710315 Q215H
P
P
Hepatitis B, Chronic
G
R
C
View
12 23710315 T128N
P
P
Hepatitis B, Chronic
G
R
C
View
13 23710315 L180M
P
P
Hepatitis B, Chronic
D
G
R
C
View
14 23710315 V173L
P
P
Hepatitis B, Chronic
G
R
C
View
15 23710315 E164D
S
S
Hepatitis B, Chronic
G
R
C
View
16 23710315 F161H
S
S
Hepatitis B, Chronic
G
R
C
View
17 23710315 G145R
S
S
Hepatitis B, Chronic
G
R
C
View
18 23710315 I195M
S
S
Hepatitis B, Chronic
G
R
C
View
19 23710315 H55R
P
P
Hepatitis B, Chronic
G
R
C
View
20 23710315 E271Q
P
P
Hepatitis B, Chronic
G
R
C
View
21 23710315 H55A
P
P
Hepatitis B, Chronic
G
R
C
View
22 23710315 T38A
P
P
Hepatitis B, Chronic
G
R
C
View
23 23710315 D134E
P
P
Hepatitis B, Chronic
G
R
C
View
24 23710315 N76D
P
P
Hepatitis B, Chronic
G
R
C
View
25 23710315 W196L
S
S
Hepatitis B, Chronic
G
R
C
View
26 23710315 A181T
P
P
Hepatitis B, Chronic
D
G
R
C
View
27 23710315 L173F
S
S
Hepatitis B, Chronic
G
R
C
View
28 23710315 R242A
P
P
Hepatitis B, Chronic
G
R
C
View
29 23710315 L175F
S
S
Hepatitis B, Chronic
G
R
C
View
30 23710315 S207R
S
S
Hepatitis B, Chronic
G
R
C
View
Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.