All Curated Mutation Sites in HBV

The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.

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Virus Gene/Protein

Disease

Description

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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BCP

Core Promoter

Core Upstream Regulatory Sequence

Keyword: Hepatitis B, Chronic-23918533

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	23918533	C256G	RT	P	Hepatitis B, Chronic	G C L	View
2	23918533	C256S	RT	P	Hepatitis B, Chronic	G C L	View
3	23918533	D263E	RT	P	Hepatitis B, Chronic	G C L	View
4	23918533	D263S	RT	P	Hepatitis B, Chronic	G C L	View
5	23918533	E271D	RT	P	Hepatitis B, Chronic	G C L	View
6	23918533	F122I	RT	P	Hepatitis B, Chronic	G C L	View
7	23918533	F122L	RT	P	Hepatitis B, Chronic	G C L	View
8	23918533	F122V	RT	P	Hepatitis B, Chronic	G C L	View
9	23918533	H126R	RT	P	Hepatitis B, Chronic	G C L	View
10	23918533	L91I	RT	P	Hepatitis B, Chronic	G C L	View
11	23918533	M129L	RT	P	Hepatitis B, Chronic	G C L	View
12	23918533	Q149K	RT	P	Hepatitis B, Chronic	G C L	View
13	23918533	S135H	RT	P	Hepatitis B, Chronic	G C L	View
14	23918533	S135Y	RT	P	Hepatitis B, Chronic	G C L	View
15	23918533	S259T	RT	P	Hepatitis B, Chronic	G C L	View
16	23918533	Y257W	RT	P	Hepatitis B, Chronic	G C L	View
17	23918533	H248N	RT	P	Hepatitis B, Chronic	G C L	View
18	23918533	A181G	RT	P	Hepatitis B, Chronic	D G C L	View
19	23918533	I233V	RT	P	Hepatitis B, Chronic	D G C L	View
20	23918533	M250I	RT	P	Hepatitis B, Chronic	D G C L	View
21	23918533	S202R	RT	P	Hepatitis B, Chronic	D G C L	View
22	23918533	I224V	RT	P	Hepatitis B, Chronic	G C L	View
23	23918533	H139H	RT	P	Hepatitis B, Chronic	C L	View
24	23918533	N238H	RT	P	Hepatitis B, Chronic	G C L	View
25	23918533	N54H	RT	P	Hepatitis B, Chronic	C L	View
26	23918533	P237H	RT	P	Hepatitis B, Chronic	C L	View
27	23918533	A128V	RT	P	Hepatitis B, Chronic	C L	View
28	23918533	A223S	RT	P	Hepatitis B, Chronic	G C L	View
29	23918533	F151Y	RT	P	Hepatitis B, Chronic	G C L	View
30	23918533	G127R	RT	P	Hepatitis B, Chronic	G C L	View
31	23918533	H124Y	RT	P	Hepatitis B, Chronic	G C L	View
32	23918533	I121N	RT	P	Hepatitis B, Chronic	G C L	View
33	23918533	I169N	RT	P	Hepatitis B, Chronic	G C L	View
34	23918533	I253R	RT	P	Hepatitis B, Chronic	G C L	View
35	23918533	I266K	RT	P	Hepatitis B, Chronic	G C L	View
36	23918533	I266R	RT	P	Hepatitis B, Chronic	G C L	View
37	23918533	I266T	RT	P	Hepatitis B, Chronic	G C L	View
38	23918533	L115V	RT	P	Hepatitis B, Chronic	G C L	View
39	23918533	L180S	RT	P	Hepatitis B, Chronic	G C L	View
40	23918533	L80V	RT	P	Hepatitis B, Chronic	G C L	View
41	23918533	M204G	RT	P	Hepatitis B, Chronic	G C L	View
42	23918533	M204I	RT	P	Hepatitis B, Chronic	D G C L	View
43	23918533	N118T	RT	P	Hepatitis B, Chronic	G C L	View
44	23918533	N139H	RT	P	Hepatitis B, Chronic	G C L	View
45	23918533	N53D	RT	P	Hepatitis B, Chronic	G C L	View
46	23918533	N53E	RT	P	Hepatitis B, Chronic	G C L	View
47	23918533	N76D	RT	P	Hepatitis B, Chronic	G C L	View
48	23918533	P237T	RT	P	Hepatitis B, Chronic	G C L	View
49	23918533	Q215S	RT	P	Hepatitis B, Chronic	G C L	View
50	23918533	Q262H	RT	P	Hepatitis B, Chronic	G C L	View
51	23918533	R289K	RT	P	Hepatitis B, Chronic	G C L	View
52	23918533	S223A	RT	P	Hepatitis B, Chronic	G C L	View
53	23918533	S78T	RT	P	Hepatitis B, Chronic	G C L	View
54	23918533	T128A	RT	P	Hepatitis B, Chronic	G C L	View
55	23918533	V173R	RT	P	Hepatitis B, Chronic	G C L	View
56	23918533	V253I	RT	P	Hepatitis B, Chronic	G C L	View
57	23918533	V286I	RT	P	Hepatitis B, Chronic	G C L	View
58	23918533	W284G	RT	P	Hepatitis B, Chronic	G C L	View
59	23918533	Y54H	RT	P	Hepatitis B, Chronic	G C L	View

Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note

D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.

G
The study mentioned the virus genotype/subtype information.

R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.

S
The study provided sequence information or accession numbers.

L
The study provided the geographic region/country of data origin.

C
The study provided clinical baseline information.

I
The study involved information related to immune.

T
The study involved host target genes.