All Curated Mutation Sites in HBV 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


Browse Data by Virus Gene/Protein/Region, Disease OR Description
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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

Show All
  
S
  
BCP
  
X
  
C
  
Core Promoter
  
Core Upstream Regulatory Sequence
  
DR1
  
EnhI
  
EnhII
  
PreC
  
P
  
PreC Promoter
  
PreS
  
PreS1
  
PreS1 Promoter
  
PreS2
  
RT
  
S Promoter
  
S1 Promoter
  
S2 Promoter
  
X Promoter
  

Keyword: Hepatitis B, Chronic-24835494
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 24835494 L180M
RT
P
Hepatitis B, Chronic
D
R
S
C
L
View
2 24835494 M204I
RT
P
Hepatitis B, Chronic
D
R
S
C
L
View
3 24835494 M204V
RT
P
Hepatitis B, Chronic
D
R
S
C
L
View
4 24835494 P120T
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
5 24835494 S85A
RT
P
Hepatitis B, Chronic
D
R
S
C
L
View
6 24835494 L80V
RT
P
Hepatitis B, Chronic
R
S
C
L
View
7 24835494 Q215S
RT
P
Hepatitis B, Chronic
R
S
C
L
View
8 24835494 M133T
S
S
Hepatitis B, Chronic
R
S
I
C
L
View
9 24835494 T126S
S
S
Hepatitis B, Chronic
R
S
I
C
L
View
10 24835494 N236T
RT
P
Hepatitis B, Chronic
D
R
S
C
L
View
11 24835494 A128V
S
S
Hepatitis B, Chronic
R
S
I
C
L
View
12 24835494 F134N
S
S
Hepatitis B, Chronic
R
S
I
C
L
View
13 24835494 G119R
S
S
Hepatitis B, Chronic
R
S
I
C
L
View
14 24835494 G130N
S
S
Hepatitis B, Chronic
R
S
I
C
L
View
15 24835494 G130R
S
S
Hepatitis B, Chronic
R
S
I
C
L
View
16 24835494 G130S
S
S
Hepatitis B, Chronic
R
S
I
C
L
View
17 24835494 P127S
S
S
Hepatitis B, Chronic
R
S
I
C
L
View
18 24835494 P127T
S
S
Hepatitis B, Chronic
R
S
I
C
L
View
19 24835494 P135L
S
S
Hepatitis B, Chronic
R
S
I
C
L
View
20 24835494 S143L
S
S
Hepatitis B, Chronic
R
S
I
C
L
View
21 24835494 S143M
S
S
Hepatitis B, Chronic
R
S
I
C
L
View
22 24835494 T118A
S
S
Hepatitis B, Chronic
R
S
I
C
L
View
23 24835494 T118K
S
S
Hepatitis B, Chronic
R
S
I
C
L
View
24 24835494 T118V
S
S
Hepatitis B, Chronic
R
S
I
C
L
View
25 24835494 T125M
S
S
Hepatitis B, Chronic
R
S
I
C
L
View
26 24835494 T126I
S
S
Hepatitis B, Chronic
R
S
I
C
L
View
27 24835494 T143L
S
S
Hepatitis B, Chronic
R
S
I
C
L
View
28 24835494 T143M
S
S
Hepatitis B, Chronic
R
S
I
C
L
View
29 24835494 Y134N
S
S
Hepatitis B, Chronic
R
S
I
C
L
View
Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.