All Curated Mutation Sites in HBV

The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.

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Virus Gene/Protein

Disease

Description

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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BCP

Core Promoter

Core Upstream Regulatory Sequence

Keyword: Hepatitis B, Chronic-27651827

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	27651827	A35E	PreS1	S	Hepatitis B, Chronic	G S C L	View
2	27651827	H44L	PreS1	S	Hepatitis B, Chronic	G S C L	View
3	27651827	K13E	PreS1	S	Hepatitis B, Chronic	G S C L	View
4	27651827	N29K	PreS1	S	Hepatitis B, Chronic	G S C L	View
5	27651827	R38K	PreS1	S	Hepatitis B, Chronic	G S C L	View
6	27651827	S90T	PreS1	S	Hepatitis B, Chronic	G S C L	View
7	27651827	V80I	PreS1	S	Hepatitis B, Chronic	G S C L	View
8	27651827	K85Q	PreS1	S	Hepatitis B, Chronic	G S C L	View
9	27651827	N14K	PreS1	S	Hepatitis B, Chronic	G S C L	View
10	27651827	N19T	PreS1	S	Hepatitis B, Chronic	G S C L	View
11	27651827	P25L	PreS1	S	Hepatitis B, Chronic	G S C L	View
12	27651827	P30Q	PreS1	S	Hepatitis B, Chronic	G S C L	View
13	27651827	P64S	PreS1	S	Hepatitis B, Chronic	G S C L	View
14	27651827	R38G	PreS1	S	Hepatitis B, Chronic	G S C L	View
15	27651827	S100V	PreS1	S	Hepatitis B, Chronic	G S C L	View
16	27651827	T52R	PreS1	S	Hepatitis B, Chronic	G S C L	View
17	27651827	V49A	PreS1	S	Hepatitis B, Chronic	G S C L	View
18	27651827	W42G	PreS1	S	Hepatitis B, Chronic	G S C L	View

Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note

D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.

G
The study mentioned the virus genotype/subtype information.

R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.

S
The study provided sequence information or accession numbers.

L
The study provided the geographic region/country of data origin.

C
The study provided clinical baseline information.

I
The study involved information related to immune.

T
The study involved host target genes.