All Curated Mutation Sites in HBV

The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.

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Virus Gene/Protein

Disease

Description

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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BCP

Core Promoter

Core Upstream Regulatory Sequence

Keyword: Hepatitis B, Chronic-28300730

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	28300730	A128V	S	S	Hepatitis B, Chronic	S I C L	View
2	28300730	P120T	S	S	Hepatitis B, Chronic	S I C L	View
3	28300730	M204I	RT	P	Hepatitis B, Chronic	S C L	View
4	28300730	M204S	RT	P	Hepatitis B, Chronic	S C L	View
5	28300730	M204V	RT	P	Hepatitis B, Chronic	S C L	View
6	28300730	E164D	S	S	Hepatitis B, Chronic	S C L	View
7	28300730	A181V	P	P	Hepatitis B, Chronic	S C L	View
8	28300730	I169V	P	P	Hepatitis B, Chronic	S C L	View
9	28300730	L173F	S	S	Hepatitis B, Chronic	S I C L	View
10	28300730	L175F	S	S	Hepatitis B, Chronic	S I C L	View
11	28300730	M250L	P	P	Hepatitis B, Chronic	S C L	View
12	28300730	N236T	P	P	Hepatitis B, Chronic	S C L	View
13	28300730	S202G	P	P	Hepatitis B, Chronic	S C L	View
14	28300730	W172S	S	S	Hepatitis B, Chronic	S I C L	View
15	28300730	D131E	P	P	Hepatitis B, Chronic	S C L	View
16	28300730	D134E	P	P	Hepatitis B, Chronic	S C L	View
17	28300730	F134R	S	S	Hepatitis B, Chronic	S I C L	View
18	28300730	G130D	S	S	Hepatitis B, Chronic	S I C L	View
19	28300730	G130N	S	S	Hepatitis B, Chronic	S I C L	View
20	28300730	G130R	S	S	Hepatitis B, Chronic	S I C L	View
21	28300730	G145A	S	S	Hepatitis B, Chronic	S I C L	View
22	28300730	G145R	S	S	Hepatitis B, Chronic	S I C L	View
23	28300730	H126Q	P	P	Hepatitis B, Chronic	S C L	View
24	28300730	I126N	S	S	Hepatitis B, Chronic	S I C L	View
25	28300730	I126S	S	S	Hepatitis B, Chronic	S I C L	View
26	28300730	M133I	S	S	Hepatitis B, Chronic	S I C L	View
27	28300730	M133L	S	S	Hepatitis B, Chronic	S I C L	View
28	28300730	M133T	S	S	Hepatitis B, Chronic	S I C L	View
29	28300730	N131S	P	P	Hepatitis B, Chronic	S C L	View
30	28300730	P120A	S	S	Hepatitis B, Chronic	S I C L	View
31	28300730	Q125H	P	P	Hepatitis B, Chronic	S C L	View
32	28300730	Q129R	S	S	Hepatitis B, Chronic	S I C L	View
33	28300730	R138K	P	P	Hepatitis B, Chronic	S C L	View
34	28300730	R153Q	P	P	Hepatitis B, Chronic	S C L	View
35	28300730	S117T	S	S	Hepatitis B, Chronic	S I C L	View
36	28300730	T118R	S	S	Hepatitis B, Chronic	S I C L	View
37	28300730	T123A	S	S	Hepatitis B, Chronic	S I C L	View
38	28300730	T123N	S	S	Hepatitis B, Chronic	S I C L	View
39	28300730	T128N	P	P	Hepatitis B, Chronic	S C L	View
40	28300730	T128S	P	P	Hepatitis B, Chronic	S C L	View
41	28300730	V142A	P	P	Hepatitis B, Chronic	S C L	View
42	28300730	V142I	P	P	Hepatitis B, Chronic	S C L	View
43	28300730	Y141F	P	P	Hepatitis B, Chronic	S C L	View
44	28300730	L180M	RT	P	Hepatitis B, Chronic	S C L	View
45	28300730	T184L	RT	P	Hepatitis B, Chronic	S C L	View
46	28300730	A181T	RT	P	Hepatitis B, Chronic	D S C L	View
47	28300730	W172X	S	S	Hepatitis B, Chronic	S I C L	View
48	28300730	T184S	RT	P	Hepatitis B, Chronic	S C L	View
49	28300730	V173L	RT	P	Hepatitis B, Chronic	S C L	View
50	28300730	I195M	S	S	Hepatitis B, Chronic	S I C L	View
51	28300730	W196L	S	S	Hepatitis B, Chronic	S I C L	View
52	28300730	W196V	S	S	Hepatitis B, Chronic	S I C L	View

Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note

D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.

G
The study mentioned the virus genotype/subtype information.

R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.

S
The study provided sequence information or accession numbers.

L
The study provided the geographic region/country of data origin.

C
The study provided clinical baseline information.

I
The study involved information related to immune.

T
The study involved host target genes.