All Curated Mutation Sites in HBV

The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.

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Virus Gene/Protein

Disease

Description

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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BCP

Core Promoter

Core Upstream Regulatory Sequence

Keyword: Hepatitis B, Chronic-28303969

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	28303969	H124N	RT	P	Hepatitis B, Chronic	D G R L	View
2	28303969	A181T	RT	P	Hepatitis B, Chronic	G R L	View
3	28303969	M204V	RT	P	Hepatitis B, Chronic	G R L	View
4	28303969	F122L	RT	P	Hepatitis B, Chronic	G R L	View
5	28303969	H122L	RT	P	Hepatitis B, Chronic	G R L	View
6	28303969	Q130P	RT	P	Hepatitis B, Chronic	G R L	View
7	28303969	N131D	RT	P	Hepatitis B, Chronic	G R L	View
8	28303969	A219S	RT	P	Hepatitis B, Chronic	G R L	View
9	28303969	H248N	RT	P	Hepatitis B, Chronic	G R L	View
10	28303969	S256C	RT	P	Hepatitis B, Chronic	G R L	View
11	28303969	R266I	RT	P	Hepatitis B, Chronic	G R L	View
12	28303969	H267Q	RT	P	Hepatitis B, Chronic	G R L	View
13	28303969	L267Q	RT	P	Hepatitis B, Chronic	G R L	View
14	28303969	A113T	S	S	Hepatitis B, Chronic	G R I L	View
15	28303969	A128V	S	S	Hepatitis B, Chronic	G R I L	View
16	28303969	A194V	S	S	Hepatitis B, Chronic	G R I L	View
17	28303969	I195M	S	S	Hepatitis B, Chronic	G R I L	View
18	28303969	I4T	S	S	Hepatitis B, Chronic	G R I L	View
19	28303969	K160R	S	S	Hepatitis B, Chronic	G R I L	View
20	28303969	L49P	S	S	Hepatitis B, Chronic	G R I L	View
21	28303969	M204I	RT	P	Hepatitis B, Chronic	G R L	View
22	28303969	N131T	S	S	Hepatitis B, Chronic	G R I L	View
23	28303969	N143S	S	S	Hepatitis B, Chronic	G R I L	View
24	28303969	N3S	S	S	Hepatitis B, Chronic	G R I L	View
25	28303969	P127T	S	S	Hepatitis B, Chronic	G R I L	View
26	28303969	R210N	S	S	Hepatitis B, Chronic	G R I L	View
27	28303969	S113T	S	S	Hepatitis B, Chronic	G R I L	View
28	28303969	S161F	S	S	Hepatitis B, Chronic	G R I L	View
29	28303969	S45A	S	S	Hepatitis B, Chronic	G R I L	View
30	28303969	S53L	S	S	Hepatitis B, Chronic	G R I L	View
31	28303969	T114S	S	S	Hepatitis B, Chronic	G R I L	View
32	28303969	T118V	S	S	Hepatitis B, Chronic	G R I L	View
33	28303969	T126I	S	S	Hepatitis B, Chronic	G R I L	View
34	28303969	V47T	S	S	Hepatitis B, Chronic	G R I L	View
35	28303969	W196L	S	S	Hepatitis B, Chronic	G R I L	View
36	28303969	Y161F	S	S	Hepatitis B, Chronic	G R I L	View
37	28303969	V278I	RT	P	Hepatitis B, Chronic	G R L	View
38	28303969	I68A	S	S	Hepatitis B, Chronic	G R I L	View
39	28303969	I68T	S	S	Hepatitis B, Chronic	G R I L	View
40	28303969	P46T	S	S	Hepatitis B, Chronic	G R I L	View
41	28303969	S202G	RT	P	Hepatitis B, Chronic	G R L	View
42	28303969	T118N	RT	P	Hepatitis B, Chronic	G R L	View
43	28303969	T125M	S	S	Hepatitis B, Chronic	G R I L	View
44	28303969	L80I	RT	P	Hepatitis B, Chronic	G R L	View
45	28303969	L180M	RT	P	Hepatitis B, Chronic	G R L	View
46	28303969	N53D	RT	P	Hepatitis B, Chronic	G R L	View
47	28303969	Y54H	RT	P	Hepatitis B, Chronic	G R L	View
48	28303969	L91I	RT	P	Hepatitis B, Chronic	G R L	View
49	28303969	I121L	RT	P	Hepatitis B, Chronic	G R L	View

Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note

D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.

G
The study mentioned the virus genotype/subtype information.

R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.

S
The study provided sequence information or accession numbers.

L
The study provided the geographic region/country of data origin.

C
The study provided clinical baseline information.

I
The study involved information related to immune.

T
The study involved host target genes.