All Curated Mutation Sites in HBV

The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.

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Virus Gene/Protein

Disease

Description

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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BCP

Core Promoter

Core Upstream Regulatory Sequence

Keyword: Hepatitis B, Chronic-28859616

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	28859616	G1896A	PreC	C	Hepatitis B, Chronic	G S C L	View
2	28859616	G1764T	BCP		Hepatitis B, Chronic	G S C L	View
3	28859616	A1762T	BCP		Hepatitis B, Chronic	G S C L	View
4	28859616	G1764A	BCP		Hepatitis B, Chronic	G S C L	View
5	28859616	A2962G	PreS1	S	Hepatitis B, Chronic	G S C L	View
6	28859616	C2964A	PreS1	S	Hepatitis B, Chronic	G S C L	View
7	28859616	G145R	S	S	Hepatitis B, Chronic	G S I C L	View
8	28859616	I126A	S	S	Hepatitis B, Chronic	G S I C L	View
9	28859616	I126S	S	S	Hepatitis B, Chronic	G S I C L	View
10	28859616	M133L	S	S	Hepatitis B, Chronic	G S I C L	View
11	28859616	M133T	S	S	Hepatitis B, Chronic	G S I C L	View
12	28859616	P120S	S	S	Hepatitis B, Chronic	G S I C L	View
13	28859616	P120T	S	S	Hepatitis B, Chronic	G S I C L	View
14	28859616	T126A	S	S	Hepatitis B, Chronic	G S I C L	View
15	28859616	T126S	S	S	Hepatitis B, Chronic	G S I C L	View
16	28859616	C1766G	BCP		Hepatitis B, Chronic	G S C L	View
17	28859616	G1757A	BCP		Hepatitis B, Chronic	G S C L	View
18	28859616	T1753C	BCP		Hepatitis B, Chronic	G S C L	View
19	28859616	N3S	PreS2	S	Hepatitis B, Chronic	G S C L	View
20	28859616	M1I	PreS2	S	Hepatitis B, Chronic	G S C L	View
21	28859616	M1T	PreS2	S	Hepatitis B, Chronic	G S C L	View
22	28859616	M1V	PreS2	S	Hepatitis B, Chronic	G S C L	View
23	28859616	G1899A	PreC	C	Hepatitis B, Chronic	G S C L	View
24	28859616	A162G	PreS2	S	Hepatitis B, Chronic	G S C L	View
25	28859616	A60E	PreS1	S	Hepatitis B, Chronic	G S C L	View
26	28859616	A60V	PreS1	S	Hepatitis B, Chronic	G S C L	View
27	28859616	A706C	S	S	Hepatitis B, Chronic	G S I C L	View
28	28859616	C3026A	PreS1	S	Hepatitis B, Chronic	G S C L	View
29	28859616	C3026T	PreS1	S	Hepatitis B, Chronic	G S C L	View
30	28859616	F22I	PreS2	S	Hepatitis B, Chronic	G S C L	View
31	28859616	F22L	PreS2	S	Hepatitis B, Chronic	G S C L	View
32	28859616	L126S	PreS2	S	Hepatitis B, Chronic	G S C L	View
33	28859616	L126T	PreS2	S	Hepatitis B, Chronic	G S C L	View
34	28859616	N38E	PreS1	S	Hepatitis B, Chronic	G S C L	View
35	28859616	N38K	PreS1	S	Hepatitis B, Chronic	G S C L	View
36	28859616	S204R	S	S	Hepatitis B, Chronic	G S I C L	View
37	28859616	T531C	PreS2	S	Hepatitis B, Chronic	G S C L	View
38	28859616	T531G	PreS2	S	Hepatitis B, Chronic	G S C L	View
39	28859616	T53C	PreS2	S	Hepatitis B, Chronic	G S C L	View
40	28859616	T766A	S	S	Hepatitis B, Chronic	G S I C L	View
41	28859616	V184A	S	S	Hepatitis B, Chronic	G S I C L	View
42	28859616	A2159G	PreC;C	C	Hepatitis B, Chronic	G S C L	View
43	28859616	A2189C	PreC;C	C	Hepatitis B, Chronic	G S C L	View
44	28859616	C1653T	BCP		Hepatitis B, Chronic	G S C L	View
45	28859616	G2203A	PreC;C	C	Hepatitis B, Chronic	G S C L	View
46	28859616	G2203T	PreC;C	C	Hepatitis B, Chronic	G S C L	View
47	28859616	T1768A	BCP		Hepatitis B, Chronic	G S C L	View
48	28859616	I126I	S	S	Hepatitis B, Chronic	G S I C L	View
49	28859616	I126N	S	S	Hepatitis B, Chronic	G S I C L	View
50	28859616	T126I	S	S	Hepatitis B, Chronic	G S I C L	View
51	28859616	T126N	S	S	Hepatitis B, Chronic	G S I C L	View

Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note

D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.

G
The study mentioned the virus genotype/subtype information.

R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.

S
The study provided sequence information or accession numbers.

L
The study provided the geographic region/country of data origin.

C
The study provided clinical baseline information.

I
The study involved information related to immune.

T
The study involved host target genes.