All Curated Mutation Sites in HBV 
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 The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.


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For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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S
  
BCP
  
X
  
C
  
Core Promoter
  
Core Upstream Regulatory Sequence
  
DR1
  
EnhI
  
EnhII
  
PreC
  
P
  
PreC Promoter
  
PreS
  
PreS1
  
PreS1 Promoter
  
PreS2
  
RT
  
S Promoter
  
S1 Promoter
  
S2 Promoter
  
X Promoter
  

Keyword: Hepatitis B, Chronic-33836203
ID PMID Mutation Gene/Protein/Region Encoding Gene/Protein Disease Description Detail
1 33836203 D144A
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
2 33836203 S143L
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
3 33836203 T125M
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
4 33836203 G130E
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
5 33836203 M103T
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
6 33836203 Y124H
RT
P
Hepatitis B, Chronic
G
R
S
C
L
View
7 33836203 Y124N
RT
P
Hepatitis B, Chronic
G
R
S
C
L
View
8 33836203 L42X Hepatitis B, Chronic
G
R
S
I
C
L
View
9 33836203 Y206N
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
10 33836203 F220C
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
11 33836203 Q101H
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
12 33836203 Q101R
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
13 33836203 R169H
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
14 33836203 E271R
RT
P
Hepatitis B, Chronic
G
R
S
C
L
View
15 33836203 G127R
RT
P
Hepatitis B, Chronic
G
R
S
C
L
View
16 33836203 I169L
RT
P
Hepatitis B, Chronic
G
R
S
C
L
View
17 33836203 L164M
RT
P
Hepatitis B, Chronic
G
R
S
C
L
View
18 33836203 M129V
RT
P
Hepatitis B, Chronic
G
R
S
C
L
View
19 33836203 N123D
RT
P
Hepatitis B, Chronic
G
R
S
C
L
View
20 33836203 N76D
RT
P
Hepatitis B, Chronic
G
R
S
C
L
View
21 33836203 R110G
RT
P
Hepatitis B, Chronic
G
R
S
C
L
View
22 33836203 R51W
RT
P
Hepatitis B, Chronic
G
R
S
C
L
View
23 33836203 S213T
RT
P
Hepatitis B, Chronic
G
R
S
C
L
View
24 33836203 S219A
RT
P
Hepatitis B, Chronic
G
R
S
C
L
View
25 33836203 P127T
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
26 33836203 A166G
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
27 33836203 K160N
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
28 33836203 N238H
RT
P
Hepatitis B, Chronic
G
R
S
C
L
View
29 33836203 D263E
RT
P
Hepatitis B, Chronic
G
R
S
C
L
View
30 33836203 A168V
S
S
Hepatitis B, Chronic
G
R
S
I
C
L
View
Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note
D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.
G
The study mentioned the virus genotype/subtype information.
R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.
S
The study provided sequence information or accession numbers.
L
The study provided the geographic region/country of data origin.
C
The study provided clinical baseline information.
I
The study involved information related to immune.
T
The study involved host target genes.