All Curated Mutation Sites in HBV

The Virus Mutation(VM) module provides researchers the annotations of reported pathogenic mutations in HBV related to human diseases. The curated VM information includes mutation site, mutation level, virus gene/protein/region, virus-associated disease, genotype/subtype, literature evidence, etc.

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Virus Gene/Protein

Disease

Description

For highly variable viruses (e.g., HBV, HIV, SARS-CoV-2), ViMIC defaults to displaying mutations in a specific region. Click the green button to search for other regions, or click "Show All" to view all mutations (loading speed may be affected by network conditions).

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BCP

Core Promoter

Core Upstream Regulatory Sequence

Keyword: Hepatitis B, Chronic-36970691

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	36970691	A106C	X	X	Hepatitis B, Chronic	G R L	View
2	36970691	A181T	RT	P	Hepatitis B, Chronic	D G R L	View
3	36970691	A181V	RT	P	Hepatitis B, Chronic	D G R L	View
4	36970691	A194T	RT	P	Hepatitis B, Chronic	D G R L	View
5	36970691	A200V	RT	P	Hepatitis B, Chronic	D G R L	View
6	36970691	A2388C	P	P	Hepatitis B, Chronic	G R L	View
7	36970691	A269T	PreS1	S	Hepatitis B, Chronic	G R L	View
8	36970691	A36P	X	X	Hepatitis B, Chronic	G R L	View
9	36970691	A814G	P	P	Hepatitis B, Chronic	G R L	View
10	36970691	A90V	PreS1	S	Hepatitis B, Chronic	G R L	View
11	36970691	C241A	P	P	Hepatitis B, Chronic	G R L	View
12	36970691	C256G	RT	P	Hepatitis B, Chronic	D G R L	View
13	36970691	D134C	PreS1	S	Hepatitis B, Chronic	G R L	View
14	36970691	D134E	PreS1	S	Hepatitis B, Chronic	G R L	View
15	36970691	D134N	PreS1	S	Hepatitis B, Chronic	G R L	View
16	36970691	E218D	RT	P	Hepatitis B, Chronic	D G R L	View
17	36970691	F166L	RT	P	Hepatitis B, Chronic	D G R L	View
18	36970691	F221Y	RT	P	Hepatitis B, Chronic	D G R L	View
19	36970691	F321L	P	P	Hepatitis B, Chronic	G R L	View
20	36970691	G106C	X	X	Hepatitis B, Chronic	G R L	View
21	36970691	G2388C	P	P	Hepatitis B, Chronic	G R L	View
22	36970691	H126C	RT	P	Hepatitis B, Chronic	D G R L	View
23	36970691	H126Q	RT	P	Hepatitis B, Chronic	D G R L	View
24	36970691	H126Y	RT	P	Hepatitis B, Chronic	D G R L	View
25	36970691	H81N	P	P	Hepatitis B, Chronic	G R L	View
26	36970691	I169L	RT	P	Hepatitis B, Chronic	D G R L	View
27	36970691	I169T	RT	P	Hepatitis B, Chronic	D G R L	View
28	36970691	I224V	RT	P	Hepatitis B, Chronic	G R L	View
29	36970691	I233V	RT	P	Hepatitis B, Chronic	D G R L	View
30	36970691	I91L	RT	P	Hepatitis B, Chronic	D G R L	View
31	36970691	L116V	X	X	Hepatitis B, Chronic	G R L	View
32	36970691	L180M	RT	P	Hepatitis B, Chronic	D G R L	View
33	36970691	L217R	RT	P	Hepatitis B, Chronic	D G R L	View
34	36970691	L229G	RT	P	Hepatitis B, Chronic	D G R L	View
35	36970691	L229V	RT	P	Hepatitis B, Chronic	D G R L	View
36	36970691	L229W	RT	P	Hepatitis B, Chronic	D G R L	View
37	36970691	L80I	RT	P	Hepatitis B, Chronic	D G R L	View
38	36970691	L82M	RT	P	Hepatitis B, Chronic	D G R L	View
39	36970691	L82V	RT	P	Hepatitis B, Chronic	D G R L	View
40	36970691	M204I	RT	P	Hepatitis B, Chronic	D G R L	View
41	36970691	M204V	RT	P	Hepatitis B, Chronic	D G R L	View
42	36970691	M250I	RT	P	Hepatitis B, Chronic	D G R L	View
43	36970691	M250L	RT	P	Hepatitis B, Chronic	D G R L	View
44	36970691	M250V	RT	P	Hepatitis B, Chronic	D G R L	View
45	36970691	N139D	RT	P	Hepatitis B, Chronic	D G R L	View
46	36970691	N139H	PreS1	S	Hepatitis B, Chronic	G R L	View
47	36970691	N139K	PreS1	S	Hepatitis B, Chronic	G R L	View
48	36970691	N236T	RT	P	Hepatitis B, Chronic	D G R L	View
49	36970691	N238D	RT	P	Hepatitis B, Chronic	D G R L	View
50	36970691	N238H	RT	P	Hepatitis B, Chronic	D G R L	View
51	36970691	N238S	RT	P	Hepatitis B, Chronic	D G R L	View
52	36970691	P237H	RT	P	Hepatitis B, Chronic	D G R L	View
53	36970691	Q215H	RT	P	Hepatitis B, Chronic	D G R L	View
54	36970691	Q215P	RT	P	Hepatitis B, Chronic	D G R L	View
55	36970691	Q215S	RT	P	Hepatitis B, Chronic	D G R L	View
56	36970691	R242A	RT	P	Hepatitis B, Chronic	G R L	View
57	36970691	RW153Q	RT	P	Hepatitis B, Chronic	D G R L	View
58	36970691	S202C	RT	P	Hepatitis B, Chronic	D G R L	View
59	36970691	S202G	RT	P	Hepatitis B, Chronic	D G R L	View
60	36970691	S202I	RT	P	Hepatitis B, Chronic	D G R L	View
61	36970691	S213T	RT	P	Hepatitis B, Chronic	D G R L	View
62	36970691	S314P	P	P	Hepatitis B, Chronic	G R L	View
63	36970691	S36P	X	X	Hepatitis B, Chronic	G R L	View
64	36970691	S53N	RT	P	Hepatitis B, Chronic	D G R L	View
65	36970691	S85A	RT	P	Hepatitis B, Chronic	D G R L	View
66	36970691	SC256G	RT	P	Hepatitis B, Chronic	D G R L	View
67	36970691	T106C	X	X	Hepatitis B, Chronic	G R L	View
68	36970691	T128I	RT	P	Hepatitis B, Chronic	D G R L	View
69	36970691	T128N	RT	P	Hepatitis B, Chronic	D G R L	View
70	36970691	T1614C	RT	P	Hepatitis B, Chronic	G R L	View
71	36970691	T1719G	X	X	Hepatitis B, Chronic	G R L	View
72	36970691	T184A	RT	P	Hepatitis B, Chronic	D G R L	View
73	36970691	T184C	RT	P	Hepatitis B, Chronic	D G R L	View
74	36970691	T184F	RT	P	Hepatitis B, Chronic	D G R L	View
75	36970691	T272A	P	P	Hepatitis B, Chronic	G R L	View
76	36970691	T36P	X	X	Hepatitis B, Chronic	G R L	View
77	36970691	T38A	PreS2	S	Hepatitis B, Chronic	G R L	View
78	36970691	T54N	RT	P	Hepatitis B, Chronic	D G R L	View
79	36970691	T551C	S	S	Hepatitis B, Chronic	G R L	View
80	36970691	T588C	RT	P	Hepatitis B, Chronic	G R L	View
81	36970691	T940C	P	P	Hepatitis B, Chronic	G R L	View
82	36970691	T961C	P	P	Hepatitis B, Chronic	G R L	View
83	36970691	V184A	S	S	Hepatitis B, Chronic	G R L	View
84	36970691	V191D	RT	P	Hepatitis B, Chronic	D G R L	View
85	36970691	V191I	RT	P	Hepatitis B, Chronic	D G R L	View
86	36970691	V207I	RT	P	Hepatitis B, Chronic	D G R L	View
87	36970691	V214A	RT	P	Hepatitis B, Chronic	D G R L	View
88	36970691	V84I	RT	P	Hepatitis B, Chronic	D G R L	View
89	36970691	V84M	RT	P	Hepatitis B, Chronic	D G R L	View
90	36970691	W153Q	RT	P	Hepatitis B, Chronic	D G R L	View
91	36970691	Y124H	PreS1	S	Hepatitis B, Chronic	G R L	View
92	36970691	Y245H	RT	P	Hepatitis B, Chronic	D G R L	View

Contents
Description

The table shows all curated mutation sites of HBV in each literature

Table Description Column Note

D
The study mentioned a certain treatment method, such as drug resistance caused by mutations.

G
The study mentioned the virus genotype/subtype information.

R
The study mentioned the reference sequence used for comparison, or the original strain of the virus used for site-directed mutagenesis.

S
The study provided sequence information or accession numbers.

L
The study provided the geographic region/country of data origin.

C
The study provided clinical baseline information.

I
The study involved information related to immune.

T
The study involved host target genes.