Gene Information
|
Gene Name
|
ARNT2 |
|
Gene ID
|
9915
|
|
Gene Full Name
|
aryl hydrocarbon receptor nuclear translocator 2 |
|
Gene Alias
|
WEDAS|bHLHe1 |
|
Transcripts
|
ENSG00000172379
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Nucleoplasm; 
|
|
Membrane Info
|
Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors |
|
Uniport_ID
|
Q9HBZ2
|
|
HGNC ID
|
HGNC:16876
|
|
OMIM ID
|
606036 |
|
Summary
|
This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting additional roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively. [provided by RefSeq, Dec 2013] |
Target gene [ARNT2] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6004098 |
chr15 |
124 |
5 |
0 |
129 |
View |
| 6013551 |
chr15 |
12 |
7 |
0 |
19 |
View |
| 6015153 |
chr15 |
12 |
2 |
1 |
15 |
View |
| 6019033 |
chr15 |
2 |
2 |
4 |
8 |
View |
| 6023916 |
chr15 |
0 |
3 |
1 |
4 |
View |
Target gene [ARNT2] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - ARNT2 peak across samples
|
Peak Plot
|
|
|
HTLV1 Target gene Detail Information
