Gene Information
|
Gene Name
|
ASIC2 |
|
Gene ID
|
40
|
|
Gene Full Name
|
acid sensing ion channel subunit 2 |
|
Gene Alias
|
ACCN|ACCN1|ASIC2a|BNC1|BNaC1|MDEG|hBNaC1 |
|
Transcripts
|
ENSG00000108684
|
|
Virus
|
HBV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
|
|
Membrane Info
|
Plasma proteins, Predicted membrane proteins |
|
Uniport_ID
|
Q16515
|
|
HGNC ID
|
HGNC:99
|
|
OMIM ID
|
601784 |
|
Summary
|
This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 3 has been observed to co-assemble into proton-gated channels sensitive to gadolinium. Alternative splicing has been observed at this locus and two variants, encoding distinct isoforms, have been identified. [provided by RefSeq, Feb 2012] |
Target gene [ASIC2] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 1009736 |
chr17 |
14 |
0 |
0 |
14 |
View |
| 1011941 |
chr17 |
8 |
0 |
0 |
8 |
View |
| 1022884 |
chr17 |
14 |
0 |
0 |
14 |
View |
| 1024055 |
chr17 |
67 |
25 |
4 |
96 |
View |
| 1042263 |
chr17 |
3 |
1 |
0 |
4 |
View |
Target gene [ASIC2] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE236281
|
RNA-seq |
12 |
Illumina MiSeq (Homo sapiens) |
|
C GSE68402
|
Chip-seq |
26 |
Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens) |
|
TCGA_LIHC_HBV
|
DNA methylation sequencing;RNA-seq |
97 |
TCGA |
|
GSE224901
|
RNA-seq |
21 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
C GSE100400
|
Chip-seq;RNA-seq;4C_cccDNA |
31 |
Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus) |
|
GSE173897
|
RNA-seq |
95 |
Illumina HiSeq 4000 (Homo sapiens) |
|
GSE262515
|
RNA-seq |
21 |
Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus) |
|
GSE110345
|
RNA-seq |
4 |
Illumina HiSeq 2500 (Homo sapiens) |
|
GSE131257
|
ATAC-seq;RNA-seq |
19 |
Illumina HiSeq 2500 (Homo sapiens) |
|
GSE94660
|
RNA-seq |
42 |
Illumina HiSeq 2500 (Homo sapiens) |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE68402 - ASIC2 peak across samples
|
Peak Plot
|
> Dataset: GSE100400 - ASIC2 peak across samples
|
Peak Plot
|
|
|
HBV Target gene Detail Information
