Gene Name	ASIC2
Gene ID	40
Gene Full Name	acid sensing ion channel subunit 2
Gene Alias	ACCN|ACCN1|ASIC2a|BNC1|BNaC1|MDEG|hBNaC1
Transcripts	ENSG00000108684
Virus	HPV
Gene Type	protein-coding
HPA Location Info
Membrane Info	Plasma proteins, Predicted membrane proteins
Uniport_ID	Q16515
HGNC ID	HGNC:99
OMIM ID	601784
Summary	This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 3 has been observed to co-assemble into proton-gated channels sensitive to gadolinium. Alternative splicing has been observed at this locus and two variants, encoding distinct isoforms, have been identified. [provided by RefSeq, Feb 2012]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5001014	chr17	39	16	4	59	View
5001015	chr17	39	16	4	59	View
5001042	chr17	36	16	4	56	View
5001219	chr17	25	11	7	43	View
5001220	chr17	25	11	7	43	View
5001266	chr17	26	8	7	41	View
5001339	chr17	22	6	10	38	View
5001412	chr17	31	4	0	35	View
5002513	chr17	7	3	0	10	View
5003373	chr17	3	1	0	4	View
5003579	chr17	3	0	0	3	View
5003580	chr17	3	0	0	3	View
5003581	chr17	2	1	0	3	View
5003604	chr17	3	0	0	3	View
5004212	chr17	1	0	0	1	View
5009113	chr17	4	0	0	4	View
5012027	chr17	24	0	0	24	View
5015157	chr17	8	7	98	113	View

Data ID	Experiment type	Sample number	Platform
GSE169622	Methylation profiling (Array)	9	Infinium MethylationEPIC
GSE181805	Expression array	25	[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE196215	RNA-seq	8	Illumina NovaSeq 6000 (Homo sapiens)
GSE138080	Expression array	35	Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version)
GSE140662	Expression array	8	[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
C   GSE143026	ATAC-seq;Chip-seq;RNA-seq	30	Illumina HiSeq 2500 (Homo sapiens)
E   TCGA_CESC	DNA methylation sequencing;RNA-seq	288	TCGA
GSE51993	Expression array	48	Illumina Human v2 MicroRNA expression beadchip;Illumina HumanHT-12 V4.0 expression beadchip
GSE165883	RNA-seq	20	Illumina NextSeq 500 (Homo sapiens)

• Expression profiling
• Genome binding/occupancy profiling

When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.

> Dataset: TCGA_CESC - ASIC2 expression across samples

Volcano Plot

Bar Plot