Gene Name	FBH1
Gene ID	84893
Gene Full Name	F-box DNA helicase 1
Gene Alias	FBXO18|Fbx18|hFBH1
Transcripts	ENSG00000134452
Virus	HTLV1
Gene Type	protein-coding
HPA Location Info
Membrane Info	Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted membrane proteins
Uniport_ID	Q8NFZ0
HGNC ID	HGNC:13620
OMIM ID	607222
Summary	This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbx class. It contains an F-box motif and seven conserved helicase motifs, and has both DNA-dependent ATPase and DNA unwinding activities. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6001150	chr10	448	99	18	565	View

Data ID	Experiment type	Sample number	Platform
GSE52244	Expression array	15	[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE224047	RNA-seq	10	Illumina NextSeq 500 (Homo sapiens)
C   GSE94732	Chip-seq	24	Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE94732 - FBH1 peak across samples

Peak Plot