Gene Information
|
Gene Name
|
KAT6B |
|
Gene ID
|
23522
|
|
Gene Full Name
|
lysine acetyltransferase 6B |
|
Gene Alias
|
GTPTS|MORF|MOZ2|MYST4|ZC2HC6B|qkf|querkopf |
|
Transcripts
|
ENSG00000156650
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Nucleoplasm, Nuclear bodies; 
|
|
Membrane Info
|
Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors |
|
Uniport_ID
|
Q8WYB5
|
|
HGNC ID
|
HGNC:17582
|
|
OMIM ID
|
605880 |
|
Summary
|
The protein encoded by this gene is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012] |
Target gene [KAT6B] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6001363 |
chr10 |
310 |
87 |
67 |
464 |
View |
| 6012521 |
chr10 |
18 |
4 |
0 |
22 |
View |
Target gene [KAT6B] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - KAT6B peak across samples
|
Peak Plot
|
|
|
HTLV1 Target gene Detail Information
