HTLV1 Target gene Detail Information

> KCNMA1 Gene Search Result


Gene Information
Gene Name KCNMA1
Gene ID 3778
Gene Full Name potassium calcium-activated channel subfamily M alpha 1
Gene Alias BKTM|CADEDS|IEG16|KCa1.1|LIWAS|MaxiK|PNKD3|SAKCA|SLO|SLO-ALPHA|SLO1|bA205K10.1|hSlo|mSLO1
Transcripts ENSG00000156113
Virus HTLV1
Gene Type protein-coding
HPA Location Info
Membrane Info Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels
Uniport_ID Q12791
HGNC ID HGNC:6284
OMIM ID 600150
Summary This gene encodes the alpha subunit of calcium-activated BK channel. The encoded protein is involved in several physiological processes including smooth muscle contraction, neurotransmitter release and neuronal excitability. Mutations in this gene are associated with a spectrum of neurological disorders including Paroxysmal Nonkinesigenic Dyskinesia 3, Idiopathic Generalized Epilepsy 16 and Liang-Wang syndrome. [provided by RefSeq, Aug 2022]
Target gene [KCNMA1] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6002544 chr10 64 151 17 232 View
6002726 chr10 174 40 0 214 View
6005250 chr10 23 37 32 92 View
6010253 chr10 17 15 0 32 View
6013158 chr10 15 4 1 20 View
6014043 chr10 6 11 0 17 View
6014227 chr10 11 6 0 17 View
6016065 chr10 2 0 11 13 View
6025622 chr10 2 1 0 3 View

Target gene [KCNMA1] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - KCNMA1 peak across samples

Peak Plot