HTLV1 Target gene Detail Information

> KCTD1 Gene Search Result


Gene Information
Gene Name KCTD1
Gene ID 284252
Gene Full Name potassium channel tetramerization domain containing 1
Gene Alias C18orf5
Transcripts ENSG00000134504
Virus HTLV1
Gene Type protein-coding
HPA Location Info Nucleoplasm;Nucleoli, Cytokinetic bridge, Centriolar satellite;
Membrane Info Disease related genes, Predicted intracellular proteins
Uniport_ID Q719H9
HGNC ID HGNC:18249
OMIM ID 613420
Summary This gene encodes a protein containing a BTB (Broad-complex, tramtrack and bric a brac), also known as a POZ (POxvirus and zinc finger) protein-protein interaction domain. The encoded protein negatively regulates the AP-2 family of transcription factors and the Wnt signaling pathway. A mechanism for the modulation of Wnt signaling has been proposed in which the encoded protein enhances ubiquitination and degradation of the beta-catenin protein. Mutations in this gene have been identified in Scalp-ear-nipple (SEN) syndrome. [provided by RefSeq, May 2017]
Target gene [KCTD1] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6002085 chr18 15 272 2 289 View
6017053 chr18 0 0 11 11 View
6017622 chr18 2 7 1 10 View
6026907 chr18 0 2 0 2 View

Target gene [KCTD1] related to Omics data
Data ID Experiment type Sample number Platform
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE224047 RNA-seq 10 Illumina NextSeq 500 (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - KCTD1 peak across samples

Peak Plot