Gene Name	KIRREL3
Gene ID	84623
Gene Full Name	kirre like nephrin family adhesion molecule 3
Gene Alias	KIRRE|MRD4|NEPH2|PRO4502
Transcripts	ENSG00000149571
Virus	HBV
Gene Type	protein-coding
HPA Location Info	Intracellular and membrane;
Membrane Info	Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins
Uniport_ID	Q8IZU9
HGNC ID	HGNC:23204
OMIM ID	607761
Summary	The protein encoded by this gene is a member of the nephrin-like protein family. These proteins are expressed in fetal and adult brain, and also in podocytes of kidney glomeruli. The cytoplasmic domains of these proteins interact with the C-terminus of podocin, also expressed in the podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. The protein encoded by this gene is a synaptic cell adhesion molecule with multiple extracellular immunoglobulin-like domains and a cytoplasmic PDZ domain-binding motif. Mutations in this gene are associated with several neurological and cognitive disorders. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2017]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1007695	chr11	21	4	0	25	View
1010544	chr11	2	9	1	12	View
1011409	chr11	9	0	0	9	View
1012341	chr11	4	3	0	7	View
1024163	chr11	7	0	0	7	View
1024256	chr11	0	0	0	0	View
1041938	chr11	10	3	3	16	View

Data ID	Experiment type	Sample number	Platform
GSE252863	scRNA-seq	10	Illumina HiSeq 2500 (Homo sapiens)
GSE236281	RNA-seq	12	Illumina MiSeq (Homo sapiens)
C   GSE35465	Chip-seq;RNA-seq	6	Illumina HiSeq 2000 (Homo sapiens)
C   GSE68402	Chip-seq	26	Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens)
GSE247322	scRNA-seq	27	Illumina NovaSeq 6000 (Homo sapiens)
TCGA_LIHC_HBV	DNA methylation sequencing;RNA-seq	97	TCGA
C   GSE270130	Chip-seq	27	Illumina NovaSeq 6000 (Homo sapiens)
GSE224901	RNA-seq	21	Illumina NovaSeq 6000 (Homo sapiens)
C   GSE100400	Chip-seq;RNA-seq;4C_cccDNA	31	Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897	RNA-seq	95	Illumina HiSeq 4000 (Homo sapiens)
GSE262515	RNA-seq	21	Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus)
GSE110345	RNA-seq	4	Illumina HiSeq 2500 (Homo sapiens)
C   GSE131257	ATAC-seq;RNA-seq	19	Illumina HiSeq 2500 (Homo sapiens)
GSE94660	RNA-seq	42	Illumina HiSeq 2500 (Homo sapiens)

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE35465 - KIRREL3 peak across samples

Peak Plot

> Dataset: GSE68402 - KIRREL3 peak across samples

Peak Plot

> Dataset: GSE270130 - KIRREL3 peak across samples

Peak Plot

> Dataset: GSE100400 - KIRREL3 peak across samples

Peak Plot

> Dataset: GSE131257 - KIRREL3 peak across samples

Peak Plot