Gene Name	MAP3K13
Gene ID	9175
Gene Full Name	mitogen-activated protein kinase kinase kinase 13
Gene Alias	LZK|MEKK13|MLK
Transcripts	ENSG00000073803
Virus	HPV
Gene Type	protein-coding
HPA Location Info	Centriolar satellite;Nucleoplasm, Cytosol;
Membrane Info	Cancer-related genes, Enzymes, Predicted intracellular proteins
Uniport_ID	O43283
HGNC ID	HGNC:6852
OMIM ID	604915
Summary	The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase contains a dual leucine-zipper motif, and has been shown to form dimers/oligomers through its leucine-zipper motif. This kinase can phosphorylate and activate MAPK8/JNK, MAP2K7/MKK7, which suggests a role in the JNK signaling pathway. [provided by RefSeq, Jul 2008]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5000641	chr3	105	5	3	113	View
5000645	chr3	103	5	3	111	View
5000647	chr3	103	4	3	110	View
5000665	chr3	101	2	3	106	View
5000677	chr3	101	2	1	104	View
5000716	chr3	88	6	2	96	View
5000729	chr3	91	2	1	94	View
5000746	chr3	80	8	3	91	View
5000805	chr3	80	1	1	82	View
5000878	chr3	72	1	1	74	View
5000908	chr3	66	2	1	69	View
5001102	chr3	49	2	1	52	View
5005275	chr3	53	47	14	114	View
5015875	chr3	252	13	10	275	View

Data ID	Experiment type	Sample number	Platform
C   GSE183048	Chip-seq	24	Illumina HiSeq 4000 (Homo sapiens)
GSE226620	scRNA-seq	30	HiSeq X Ten (Homo sapiens)
GSE139324	scRNA-seq	63	Illumina NextSeq 500 (Homo sapiens)
GSE169622	Methylation profiling (Array)	9	Infinium MethylationEPIC
GSE65858	Expression array	270	Illumina HumanHT-12 V4.0 expression beadchip
GSE181805	Expression array	25	[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE196215	RNA-seq	8	Illumina NovaSeq 6000 (Homo sapiens)
S   GSE164690	scRNA-seq	51	Illumina NextSeq 500 (Homo sapiens)
GSE138080	Expression array	35	Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version)
GSE140662	Expression array	8	[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE55542	Expression array	36	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
C   GSE143026	ATAC-seq;Chip-seq;RNA-seq	30	Illumina HiSeq 2500 (Homo sapiens)
TCGA_CESC	DNA methylation sequencing;RNA-seq	288	TCGA
GSE51993	Expression array	48	Illumina Human v2 MicroRNA expression beadchip;Illumina HumanHT-12 V4.0 expression beadchip
GSE197461	scRNA-seq	16	Illumina NovaSeq 6000 (Homo sapiens)
GSE55550	Expression array	155	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
GSE165883	RNA-seq	20	Illumina NextSeq 500 (Homo sapiens)

• scRNA data
• Genome binding/occupancy profiling

When the query gene is differentially changed in the dataset, a feature/violin plot will be displayed.

> Dataset: GSE164690 - Gene expression in cell subsets