Gene Information
|
Gene Name
|
MX1 |
|
Gene ID
|
4599
|
|
Gene Full Name
|
MX dynamin like GTPase 1 |
|
Gene Alias
|
IFI-78K|IFI78|MX|MxA|lncMX1-215 |
|
Transcripts
|
ENSG00000157601
|
|
Virus
|
IV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Nuclear membrane, Cytosol; 
|
|
Membrane Info
|
Predicted intracellular proteins |
|
Uniport_ID
|
P20591
|
|
HGNC ID
|
HGNC:7532
|
|
OMIM ID
|
147150 |
|
Summary
|
This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that participates in the cellular antiviral response. The encoded protein is induced by type I and type II interferons and antagonizes the replication process of several different RNA and DNA viruses. There is a related gene located adjacent to this gene on chromosome 21, and there are multiple pseudogenes located in a cluster on chromosome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] |
Target gene [MX1] related to virus gene/protein/region 
Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section
Target gene [MX1] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
S GSE243629
|
scRNA-seq |
11 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
C GSE225706
|
Chip-seq |
6 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
E GSE135069
|
RNA-seq |
10 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
C GSE113702
|
Chip-seq |
52 |
Illumina NextSeq 500 (Homo sapiens);Illumina HiSeq 4000 (Homo sapiens) |
|
S GSE162632
|
scRNA-seq |
292 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
GSE191176
|
scRNA-seq |
6 |
Illumina HiSeq 4000 (Homo sapiens) |
|
C GSE225704
|
ATAC-seq |
3 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
E C GSE156060
|
Chip-seq;RNA-seq |
28 |
Illumina NovaSeq 6000 (Homo sapiens) |
When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.
> Dataset: GSE135069 - MX1 expression across samples
|
Volcano Plot
|
Bar Plot
|
> Dataset: GSE156060 - MX1 expression across samples
|
Volcano Plot
|
Bar Plot
|
|
|
IV Target gene Detail Information
