Gene Information
|
Gene Name
|
PALS2 |
|
Gene ID
|
51678
|
|
Gene Full Name
|
protein associated with LIN7 2, MAGUK p55 family member |
|
Gene Alias
|
MPP6|VAM-1|VAM1|p55T |
|
Transcripts
|
ENSG00000105926
|
|
Virus
|
HPV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
|
|
Membrane Info
|
Predicted intracellular proteins |
|
Uniport_ID
|
Q9NZW5
|
|
HGNC ID
|
HGNC:18167
|
|
OMIM ID
|
606959 |
|
Summary
|
Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like (see CASK; MIM 300172), based on their size and the presence of additional domains. MPP6 is a member of the p55-like MAGUK subfamily (Tseng et al., 2001 [PubMed 11311936]).[supplied by OMIM, Mar 2008] |
Target gene [PALS2] related to VISs
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 5002547 |
chr7 |
7 |
3 |
0 |
10 |
View |
Target gene [PALS2] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
C GSE183048
|
Chip-seq |
24 |
Illumina HiSeq 4000 (Homo sapiens) |
|
GSE140662
|
Expression array |
8 |
[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version] |
|
C GSE143026
|
ATAC-seq;Chip-seq;RNA-seq |
30 |
Illumina HiSeq 2500 (Homo sapiens) |
|
GSE181805
|
Expression array |
25 |
[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version] |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE183048 - PALS2 peak across samples
|
Peak Plot
|
> Dataset: GSE143026 - PALS2 peak across samples
|
Peak Plot
|
|
|