Gene Information
|
Gene Name
|
POU6F2 |
|
Gene ID
|
11281
|
|
Gene Full Name
|
POU class 6 homeobox 2 |
|
Gene Alias
|
RPF-1|WT5|WTSL |
|
Transcripts
|
ENSG00000106536
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
|
|
Membrane Info
|
Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors |
|
Uniport_ID
|
P78424
|
|
HGNC ID
|
HGNC:21694
|
|
OMIM ID
|
609062 |
|
Summary
|
This gene encodes a member of the POU protein family characterized by the presence of a bipartite DNA binding domain, consisting of a POU-specific domain and a homeodomain, separated by a variable polylinker. The DNA binding domain may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner. The POU family members are transcriptional regulators, many of which are known to control cell type-specific differentiation pathways. This gene is a tumor suppressor involved in Wilms tumor (WT) predisposition. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[provided by RefSeq, Oct 2009] |
Target gene [POU6F2] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6009621 |
chr7 |
25 |
10 |
1 |
36 |
View |
| 6011218 |
chr7 |
9 |
14 |
4 |
27 |
View |
| 6018567 |
chr7 |
6 |
3 |
0 |
9 |
View |
| 6021280 |
chr7 |
6 |
0 |
0 |
6 |
View |
| 6022405 |
chr7 |
4 |
0 |
1 |
5 |
View |
| 6028889 |
chr7 |
1 |
0 |
0 |
1 |
View |
Target gene [POU6F2] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - POU6F2 peak across samples
|
Peak Plot
|
|
|
HTLV1 Target gene Detail Information
