Gene Information
|
Gene Name
|
PPIB |
|
Gene ID
|
5479
|
|
Gene Full Name
|
peptidylprolyl isomerase B |
|
Gene Alias
|
CYP-S1|CYPB|HEL-S-39|OI9|SCYLP |
|
Transcripts
|
ENSG00000166794
|
|
Virus
|
HCV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Endoplasmic reticulum;Nucleoplasm;Secreted to blood; 
|
|
Membrane Info
|
Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins |
|
Uniport_ID
|
P23284
|
|
HGNC ID
|
HGNC:9255
|
|
OMIM ID
|
123841 |
|
Summary
|
The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta. [provided by RefSeq, Oct 2009] |
Target gene [PPIB] related to virus gene/protein/region 
Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section
| ID |
PMID |
Mutation |
Gene/Protein/Region |
Encoding Gene/Protein |
Disease |
Description |
Detail |
| 1 |
17376913 |
I432V |
NS5B
|
NS5B
|
HCV Infection
|
D
T
|
View |
Target gene [PPIB] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
TCGA_LIHC_HCV
|
DNA methylation sequencing;RNA-seq |
97 |
TCGA |
|
GSE126831
|
RNA-seq |
63 |
Illumina NextSeq 500 (Homo sapiens) |
|
GSE212871
|
RNA-seq |
128 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
GSE103730
|
Chip-seq;RNA-seq |
42 |
Illumina HiSeq 2500 (Homo sapiens) |
|
C GSE103728
|
Chip-seq |
24 |
Illumina HiSeq 2500 (Homo sapiens) |
|
GSE67848
|
RNA-seq |
12 |
Illumina HiSeq 2500 (Homo sapiens) |
|
GSE211161
|
RNA-seq |
4 |
Illumina HiSeq 2500 (Homo sapiens) |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE103728 - PPIB peak across samples
|
Peak Plot
|
|
|
HCV Target gene Detail Information
