HBV Target gene Detail Information

> VKORC1L1 Gene Search Result


Gene Information
Gene Name VKORC1L1
Gene ID 154807
Gene Full Name vitamin K epoxide reductase complex subunit 1 like 1
Gene Alias -
Transcripts ENSG00000196715
Virus HBV
Gene Type protein-coding
HPA Location Info Endoplasmic reticulum;
Membrane Info Enzymes, FDA approved drug targets, Predicted membrane proteins
Uniport_ID Q8N0U8
HGNC ID HGNC:21492
OMIM ID 608838
Summary This gene encodes an enzyme important in the vitamin K cycle, which is involved in the carboxylation of glutamate residues present in vitamin K-dependent proteins. The encoded enzyme catalyzes the de-epoxidation of vitamin K 2,3-epoxide. Oxidative stress may upregulate expression of this gene and the encoded protein may protect cells and membrane proteins form oxidative damage. This gene and a related gene (Gene ID: 79001) may have arisen by gene duplication of an ancestral gene. [provided by RefSeq, Oct 2016]
Target gene [VKORC1L1] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1015379 chr7 2 0 0 2 View
1016117 chr7 2 0 0 2 View
1016474 chr7 1 0 0 1 View
1041528 chr7 313 245 812 1370 View

Target gene [VKORC1L1] related to Omics data
Data ID Experiment type Sample number Platform
GSE236281 RNA-seq 12 Illumina MiSeq (Homo sapiens)
C
  GSE35465 		Chip-seq;RNA-seq 6 Illumina HiSeq 2000 (Homo sapiens)
C
  GSE68402 		Chip-seq 26 Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens)
TCGA_LIHC_HBV DNA methylation sequencing;RNA-seq 97 TCGA
C
  GSE270130 		Chip-seq 27 Illumina NovaSeq 6000 (Homo sapiens)
GSE224901 RNA-seq 21 Illumina NovaSeq 6000 (Homo sapiens)
GSE100400 Chip-seq;RNA-seq;4C_cccDNA 31 Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897 RNA-seq 95 Illumina HiSeq 4000 (Homo sapiens)
GSE262515 RNA-seq 21 Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus)
GSE110345 RNA-seq 4 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE131257 		ATAC-seq;RNA-seq 19 Illumina HiSeq 2500 (Homo sapiens)
GSE94660 RNA-seq 42 Illumina HiSeq 2500 (Homo sapiens)


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE35465 - VKORC1L1 peak across samples

Peak Plot

> Dataset: GSE68402 - VKORC1L1 peak across samples

Peak Plot

> Dataset: GSE270130 - VKORC1L1 peak across samples

Peak Plot

> Dataset: GSE131257 - VKORC1L1 peak across samples

Peak Plot