Gene Name	VRK2
Gene ID	7444
Gene Full Name	VRK serine/threonine kinase 2
Gene Alias	-
Transcripts	ENSG00000028116
Virus	HPV
Gene Type	protein-coding
HPA Location Info	Endoplasmic reticulum;
Membrane Info	Enzymes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q86Y07
HGNC ID	HGNC:12719
OMIM ID	602169
Summary	This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. The encoded protein acts as an effector of signaling pathways that regulate apoptosis and tumor cell growth. Variants in this gene have been associated with schizophrenia. Alternative splicing results in multiple transcript variants that differ in their subcellular localization and biological activity. [provided by RefSeq, Jan 2014]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5004890	chr2	4	0	1	5	View
5005217	chr2	1	3	0	4	View
5005451	chr2	0	0	0	0	View
5015470	chr2	61	1	0	62	View
5015471	chr2	43	2	2	47	View
5015472	chr2	323	8	1	332	View
5015473	chr2	291	59	2	352	View
5015474	chr2	80	5	0	85	View
5015475	chr2	135	2	0	137	View
5015476	chr2	150	7	3	160	View
5015477	chr2	60	1	1	62	View
5015478	chr2	31	188	53	272	View
5015479	chr2	82	10	1	93	View
5015480	chr2	2	1	0	3	View
5015481	chr2	2	1	0	3	View
5015482	chr2	15	49	12	76	View
5015483	chr2	0	4	0	4	View
5015484	chr2	55	20	2	77	View
5015485	chr2	17	0	0	17	View

Data ID	Experiment type	Sample number	Platform
C   GSE183048	Chip-seq	24	Illumina HiSeq 4000 (Homo sapiens)
GSE226620	scRNA-seq	30	HiSeq X Ten (Homo sapiens)
GSE40774	Expression array	134	Agilent-026652 Whole Human Genome Microarray 4x44K v2 (Probe Name version)
GSE169622	Methylation profiling (Array)	9	Infinium MethylationEPIC
GSE65858	Expression array	270	Illumina HumanHT-12 V4.0 expression beadchip
GSE181805	Expression array	25	[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE196215	RNA-seq	8	Illumina NovaSeq 6000 (Homo sapiens)
GSE138080	Expression array	35	Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version)
GSE140662	Expression array	8	[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
GSE55542	Expression array	36	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
C   GSE143026	ATAC-seq;Chip-seq;RNA-seq	30	Illumina HiSeq 2500 (Homo sapiens)
TCGA_CESC	DNA methylation sequencing;RNA-seq	288	TCGA
GSE51993	Expression array	48	Illumina Human v2 MicroRNA expression beadchip;Illumina HumanHT-12 V4.0 expression beadchip
GSE197461	scRNA-seq	16	Illumina NovaSeq 6000 (Homo sapiens)
GSE55550	Expression array	155	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)
GSE165883	RNA-seq	20	Illumina NextSeq 500 (Homo sapiens)

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE183048 - VRK2 peak across samples

Peak Plot

> Dataset: GSE143026 - VRK2 peak across samples

Peak Plot