HIV Target gene Detail Information

> WARS1 Gene Search Result


Gene Information
Gene Name WARS1
Gene ID 7453
Gene Full Name tryptophanyl-tRNA synthetase 1
Gene Alias GAMMA-2|HMN9|HMND9|IFI53|IFP53|NEDMSBA|WARS
Transcripts ENSG00000140105
Virus HIV
Gene Type protein-coding
HPA Location Info Cytosol;
Membrane Info Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins
Uniport_ID P23381
HGNC ID HGNC:12729
OMIM ID 191050
Summary Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. Tryptophanyl-tRNA synthetase (WARS) catalyzes the aminoacylation of tRNA(trp) with tryptophan and is induced by interferon. Tryptophanyl-tRNA synthetase belongs to the class I tRNA synthetase family. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Target gene [WARS1] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4001404 chr14 158 11 0 169 View

Target gene [WARS1] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE220859 		Chip-seq 11 Illumina NovaSeq 6000 (Homo sapiens)
GSE128121 RNA-seq 16 Illumina HiSeq 4000 (Homo sapiens)
GSE165708 RNA-seq 100 Illumina HiSeq 4000 (Homo sapiens)
E
 
C
  GSE211651 		Chip-seq;RNA-seq;PRO-seq 39 Illumina NextSeq 500 (Homo sapiens);Illumina NovaSeq 6000 (Homo sapiens)
GSE162914 RNA-seq 211 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE221688 		Chip-seq;scATAC-Seq;scRNA-Seq 12 Illumina NovaSeq 6000 (Homo sapiens)
E
  GSE144332 		RNA-seq 75 NextSeq 550 (Homo sapiens)
GSE68028 MeDIP-chip 1 NimbleGen Human DNA Methylation 2.1M Deluxe Promoter Array [100929_HG19_Deluxe_Prom_Meth_HX1]
C
  GSE100376 		ATAC-seq 24 Illumina NextSeq 500 (Homo sapiens)
C
  GSE165705 		Chip-seq 30 Illumina NovaSeq 6000 (Homo sapiens)
C
  GSE144329 		ATAC-seq 96 NextSeq 550 (Homo sapiens)
GSE205204 RNA-seq 14 Illumina NovaSeq 6000 (Homo sapiens)
GSE167211 RNA-seq 1 Illumina HiSeq 2000 (Homo sapiens)
GSE246082 RNA-seq 6 Illumina HiSeq 4000 (Homo sapiens)
C
  GSE165703 		ATAC-seq 82 Illumina HiSeq 4000 (Homo sapiens)
C
  GSE100266 		ATAC-seq;Chip-seq;RNA-seq 32 Illumina HiSeq 2500 (Homo sapiens)
GSE125686 RNA-seq 62 Illumina HiSeq 2000 (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens);Illumina NextSeq 500 (Homo sapiens)
GSE164264 RNA-seq 6 BGISEQ-500 (Homo sapiens)


When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.


> Dataset: GSE211651 - WARS1 expression across samples

Volcano Plot

Bar Plot

> Dataset: GSE144332 - WARS1 expression across samples

Volcano Plot

Bar Plot