Evidence Details for Calca
PMID Title Journal Year Abstract
2735200 Increased survival of ischaemic musculocutaneous flaps in rats after acupuncture. Acta Physiol Scand. 1989 Apr;135(4):555-8. doi: 10.1111/j.1748-1716.1989.tb08616.x. 1989 Apr The effects of acupuncture on survival of ischaemic musculocutaneous flaps were investigated in the rat. A dorsal cranially based standard flap (2 X 7 cm) was elevated and sutured back in position. The percentage survival of the flaps was estimated after 6 days. Manual acupuncture, electro-acupuncture but not superficial acupuncture significantly increased the survival of the flaps compared to untreated controls. The highest flap survival (92%) was obtained with repeated post-operative high-intensity electro-acupuncture. It is concluded that acupuncture treatment markedly increases experimental flap survival and may be of clinical importance for treatment of local ischaemia."

Evidence Sentence: A release of the neuropeptides substance P and/or calcitonin gene-related peptide (CGRP) may be responsible for this effect (Lembeck & Gamse 1982, Couture & Cuello 1984, Brain & Williams 1985,Brainetal.1985,Gamse&Saria1985).