| 12834907 |
Electroacupuncture induces the expression of Fos in rat dorsal horn via capsaicin-insensitive afferents. |
Brain Res. 2003 Jul 18;978(1-2):136-40. doi: 10.1016/s0006-8993(03)02800-2. |
2003 Jul 18 |
Fos is expressed in rat dorsal horn neurons after electroacupuncture (E-acupuncture), but it is unclear which types of afferent fibers are involved in the expression. It is thought that the Fos expression is induced via Adelta afferents rather than C afferents, since the threshold of Adelta afferents to electrical stimulation is much lower than that of unmyelinated ones. Therefore, neonatally capsaicin treated rats lacking many C afferents were examined to clarify this. Fos expression in the dorsal horn after injection of formalin into the hindpaw was severely attenuated by neonatal capsaicin treatment. However, Fos expression after E-acupuncture to the pads of the hindpaw was unaffected by the same treatment. These results suggest that E-acupuncture induces the expression of Fos in the dorsal horn neurons via capsaicin-insensitive afferents, presumably Adelta afferents."
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