Description Baihui (GV20), Hegu (LI 4), Neiguan (PC 6), Shenmen (HT 7) and Zusanli (ST 36) at both sides
Experimental Description
Total of 118 elderly patients who underwent gastrointestinal tumor resection in our hospital from June 2018 to March 2021 were selected and divided into the control group (59 cases) and the observation group (59 cases) according to the random number method. General anesthesia was adopted in the control group and EA anesthesia combined with general anesthesia was adopted in the observation group.
Sample Count
118
Age
60-82
Control
Std
General anesthesia(n=59)
Experiment
EA anesthesia combined with general anesthesia(n=59)
Indicator
Fasting venous bloodCortisol(Cor)endothelin(ET)Norepinephrine(NE)Dopamine(DA)TNF-αIL-6IL-1βCD3CD4CD4/CD8Cognitive impairmentNauseaVomitingVisual analog scale(VAS)Patients' agitation during the surgeryPatient's respiratory normalization timeintestinal obstructionintestinal adhesion
Auxiliary Medication
In the control group patients were anesthetized and induced by intravenous midazolam injection (50 µg/kg), phenolphthalein citrate injection (4 µg/kg), propofol emulsion injection (1.5 mg/kg) and vecuronium bromide injection (0.1 mg/kg) before operation. After tracheal intubation, anesthesia was maintained with remifentanil hydrochloride for injection (continuous pumping) and sevoflurane (mask semi-closed inhalation, concentration of 4%, and oxygen flow of 3 L/min).
Stimulation Method
EA
Induction Method
Electroacupuncture Instrument Model
Manufacturer
Frequency
Waveform
Strength
Induction Time
-
-
-
dense wave
adjusted from small to large to the maximum tolerance intensity according to the slow tolerance of the patients
20 min
Acupuncture_Needle
Needle_Manufacturer
Needle_Depth
-
-
-
Description In the observation group the patients were treated with acupuncture at Baihui (GV20), Hegu (LI 4), Neiguan (PC 6), Shenmen (HT 7) and Zusanli (ST 36) at both sides 20 min before anesthesia induction. After twirling to Deqi, they were connected to the electroacupuncture therapeutic apparatus.
Anesthesia Method
AAA
Clinical Trial Type
random
Effector
The VAS score, agitation score and respiratory normalization time in the observation group were lower than those in the control group (p < 0.05). After surgery, the levels of serum Cor, ET, NE and DA in the observation group were lower than those in the control group (p < 0.05). At 24 h after surgery, the levels of serum TNF-α, IL-6 and IL-1β in the observation group were lower than those in the control group (p < 0.05). At 24 h after surgery, the levels of CD3+, CD4+, and CD4+//CD8+ in the two groups were lower than those before surgery, and the levels of CD3+, CD4+, and CD4+//CD8+ in the observation group were higher than those in the control group (p < 0.05). During the hospitalization, the total incidence rate of adverse reactions after anesthesia in the observation group was lower than that in the control group (p < 0.05). EA anesthesia combined with general anesthesia has good anesthesia effect when used for gastrointestinal tumor resection in the elderly. It can stabilize the internal environment of patients, alleviate postoperative stress response and inflammatory response, and regulate the body immune function. Moreover, it has high safety and can significantly reduce the occurrence of postoperative adverse reactions.
Effect Observation of Electro-Acupuncture Anesthesia Combined with General Anesthesia in Elderly Patients Undergoing Gastrointestinal Tumor Resection.
Abstract
OBJECTIVE: To investigate the anesthetic effect of electro-acupuncture (EA) anesthesia combined with general anesthesia in elderly patients undergoing gastrointestinal tumor resection, and to analyze the effects of EA anesthesia on inflammatory factors, stress state and T lymphocyte subsets in elderly patients. METHODS: Total of 118 elderly patients who underwent gastrointestinal tumor resection in our hospital from June 2018 to March 2021 were selected and divided into the control group (59 cases) and the observation group (59 cases) according to the random number method. General anesthesia was adopted in the control group and EA anesthesia combined with general anesthesia was adopted in the observation group. The anesthesia effect, stress state, levels of inflammatory factors, T-lymphocyte subsets and adverse reactions were compared. RESULTS: The VAS score, agitation score and respiratory normalization time in the observation group were lower than those in the control group (p < 0.05). After surgery, the levels of serum Cor, ET, NE and DA in the observation group were lower than those in the control group (p < 0.05). At 24 h after surgery, the levels of serum TNF-alpha, IL-6 and IL-1beta in the observation group were lower than those in the control group (p < 0.05). At 24 h after surgery, the levels of CD3+ , CD4+ , and CD4+//CD8+ in the two groups were lower than those before surgery, and the levels of CD3+ , CD4+ , and CD4+//CD8+ in the observation group were higher than those in the control group (p < 0.05). During the hospitalization, the total incidence rate of adverse reactions after anesthesia in the observation group was lower than that in the control group (p < 0.05). CONCLUSION: EA anesthesia combined with general anesthesia has good anesthesia effect when used for gastrointestinal tumor resection in the elderly. It can stabilize the internal environment of patients, alleviate postoperative stress response and inflammatory response, and regulate the body immune function. Moreover, it has high safety and can significantly reduce the occurrence of postoperative adverse reactions."
Souce
Front Surg. 2022 May 12;9:901638. doi: 10.3389/fsurg.2022.901638. eCollection 2022.
