Description bilateral Hegu (LI 4), Neiguan (PC 6), Houxi (SI 3), and Zhigou (TE 6)
Experimental Description
A total of 80 patients were randomized into two groups: the TEAS group and the sham TEAS combined with general anesthesia group.
Sample Count
80
Age
18-64
Control
Sham
sham TEAS combined with general anesthesia group(n=40)
Experiment
TEAS group(n=40)
Indicator
Visual analog scale(VAS)Bispectral index(BIS)Observer's assessment of alertness/sedation(OAAS)Sufentanil consumptionNumber of total and effective attempts of PCIA pump usePostoperative Nausea and Vomiting(PONV)
Auxiliary Medication
After 30 minutes of TEAS or sham‐TEAS, intravenous induction was started with 0.3–0.5 μg/kg sufentanil, 2 mg/kg propofol, and 0.6–1 mg/kg rocuronium bromide. Propofol and sufentanil were infused continuously, while rocuronium bromide was administered intermittently for anesthetic maintenance. Target‐controlled infusion of propofol was performed and the infusion rate of propofol was adjusted based on the BIS (score 40–60). For the target‐controlled infusion of sufentanil, the infusion rate was adjusted based on hemodynamic parameters. At 30 minutes before the end of the procedure, 10 μg sufentanil was administered for analgesia transition. A patient‐controlled intravenous analgesia (PCIA) pump was connected (sufentanil 1.5 μg/mL, priming volume: 0, PCIA dose: 3 mL, background dose: 2 mL/h, interval: 15 minutes, and duration: two days).
Stimulation Method
TEAS
Induction Method
Electroacupuncture Instrument Model
Manufacturer
Frequency
Waveform
Strength
Induction Time
HANS-200A
Nanjing Jisheng Medical Technology Co., Ltd., Nanjing, Jiangsu, China
2/100 Hz
continuous stimulation (30 mA) throughout the surgical procedure, and intermittent stimulations (10–15 mA) for 30 minutes each at six, 24, and 48 hours after the surgery.
10-15 mA(before anesthetic induction/at six, 24, and 48 hours after the surgery);30 mA(throughout the surgical procedure);
Patients in the TEAS group received electrical stimulation for 30 minutes before anesthetic induction, continuous stimulation throughout the surgical procedure, and intermittent stimulations for 30 minutes each at six, 24, and 48 hours after the surgery
Acupuncture_Needle
Needle_Manufacturer
Needle_Depth
-
-
-
Description Patients in the TEAS group received electrical stimulation (10–15 mA) for 30 minutes before anesthetic induction, continuous stimulation (30 mA) throughout the surgical procedure, and intermittent stimulations (10–15 mA) for 30 minutes each at six, 24, and 48 hours after the surgery.
Anesthesia Method
AAA
Clinical Trial Type
random
Effector
Patients in the TEAS group had significantly lower VAS scores at six, 24, and 48 hours after surgery (P < 0.01); lower BIS scores at 10, 20, and 30 minutes before induction (P < 0.01); lower levels of postoperative sufentanil consumption; lower number of PCIA attempts and effective rates (P < 0.01); lower incidences of nausea at 0, six, 24, and 48 hours; and lower incidence of vomiting at 24 hours after surgery (P < 0.05). The postoperative OAAS scores were similar between the groups.
"Efficacy of transcutaneous electrical acupoint stimulation combined with general anesthesia for sedation and postoperative analgesia in minimally invasive lung cancer surgery: A randomized, double-blind, placebo-controlled trial."
Abstract
BACKGROUND: Multimodal opioid-sparing analgesia is a key component of an enhanced recovery pathway after surgery that aims to improve postoperative recovery. Transcutaneous electrical acupoint stimulation (TEAS) is assumed to alleviate pain and anxiety and to modify the autonomic nervous system. This study aimed to determine the efficacy of TEAS for sedation and postoperative analgesia in lung cancer patients undergoing thoracoscopic pulmonary resection. METHODS: A total of 80 patients were randomized into two groups: the TEAS group and the sham TEAS combined with general anesthesia group. Postoperative pain levels at six, 24, 48 hours, and one month after surgery were measured using the visual analogue scale (VAS). Bispectral index (BIS) score during the TEAS prior to anesthetic induction, Observer's Assessment of Alertness/Sedation (OAAS) score, sufentanil consumption during postoperative patient-controlled intravenous analgesia (PCIA), number of total and effective attempts of PCIA pump use, and incidence of postoperative nausea and vomiting were recorded and analyzed statistically. RESULTS: Patients in the TEAS group had significantly lower VAS scores at six, 24, and 48 hours after surgery (P < 0.01); lower BIS scores at 10, 20, and 30 minutes before induction (P < 0.01); lower levels of postoperative sufentanil consumption; lower number of PCIA attempts and effective rates (P < 0.01); lower incidences of nausea at 0, six, 24, and 48 hours; and lower incidence of vomiting at 24 hours after surgery (P < 0.05). The postoperative OAAS scores were similar between the groups. CONCLUSIONS: TEAS could be a feasible approach for sedation and postoperative analgesia in thoracoscopic pulmonary resection."
Souce
Thorac Cancer. 2020 Apr;11(4):928-934. doi: 10.1111/1759-7714.13343. Epub 2020 Feb 16.
