A double-blind randomised controlled study of acupuncture versus placebo was performed in 81 patients scheduled for day case gynaecological laparoscopic surgery.
Sample Count
81
Control
Placebo
placebo(n=41)
Experiment
acupuncture(n=40)
Indicator
AgeWeightPostoperative Nausea and Vomiting(PONV)Motion sicknessPostoperative administration of morphinePost-operative administration of ondansetronLaparoscopy typeMenstrual phase
Auxiliary Medication
Anaesthesia was induced with propofol 2.5 mg.kg-1 and maintained with nitrous oxide (66%) in oxygen and isoflurane 1%. Muscle relaxation was provided by atracurium 0.3 mg.kg-1 and intermittent positive pressure ventilation of the lungs was provided via a laryngeal mask airway. Following induction and the application of acupuncture in the test group, morphine 0.15 mg.kg-1 was given intramuscularly and diclofenac 100 mg per rectum. Residual neuromuscular blockade was antagonised in all patients with neostigmine 2.5 mg and glycopyrrolate 0.5 mg. Intramuscular morphine was prescribed for postoperative pain and intravenous ondansetron for postoperative nausea or vomiting.
Stimulation Method
MS
Induction Method
Electroacupuncture Instrument Model
Manufacturer
Frequency
Waveform
Strength
Induction Time
-
-
-
-
-
The average time of PC6 acupuncture stimulation was 20 min in the study group.
Acupuncture_Needle
Needle_Manufacturer
Needle_Depth
0.18 mm in diameter
-
5 mm
Description In the study group, after induction of anaesthesia but before the start of surgery and before administration of morphine, a sterile acupuncture needle (0.18mm in diameter) was inserted bilaterally at the PC6 point which is located three fingers breadth proximal to the proximal flexor palmar crease at a depth of 5mm between the tendons of flexor carpi radialis and palmaris longus. The needles were rotated manually for 5s and left in situ for the duration of the surgery. The acupuncture needles were removed at the end of surgery.
Anesthesia Method
AAA
Clinical Trial Type
random
Effector
The use of acupuncture reduced the incidence of postoperative nausea or vomiting in hospital from 65% to 35% compared with placebo and after discharge from 69% to 31% compared with placebo.
Acupuncture in the prevention of postoperative nausea and vomiting.
Abstract
The efficacy of intra-operative acupuncture at the PC6 point in the prevention of postoperative nausea or vomiting was studied. A double-blind randomised controlled study of acupuncture versus placebo was performed in 81 patients scheduled for day case gynaecological laparoscopic surgery. Failure of treatment was defined as the occurrence of nausea or vomiting prior to or within 24 h of discharge. The use of acupuncture reduced the incidence of postoperative nausea or vomiting in hospital from 65% to 35% compared with placebo and after discharge from 69% to 31% compared with placebo.
