Gene symbol: Hspa1a

Also known as: HSP72; Hspa1; HSP70-2; HSP70.1; HSP70.2; Hsp70-1

Organism: Rattus norvegicus

Summary: Enables NF-kappaB binding activity and protease binding activity. Involved in several processes, including negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of vasoconstriction; and positive regulation of T cell mediated cytotoxicity. Located in several cellular components, including apical plasma membrane; basolateral plasma membrane; and membrane raft. Part of protein-containing complex. Human ortholog(s) of this gene implicated in several diseases, including brain ischemia; obesity; toxic shock syndrome; type 2 diabetes mellitus; and urinary tract infection. Orthologous to human HSPA1B (heat shock protein family A (Hsp70) member 1B). [provided by Alliance of Genome Resources, Apr 2022]

NCBI gene ID: 24472 EnsemblRapid:ENSRNOG00000045654 AllianceGenome:RGD:2840


GO Annotation


Category Term ID Term description
Process GO:0000003 Reproduction
Process GO:0000122 Negative regulation of transcription by RNA polymerase II
Process GO:0000723 Telomere maintenance
Process GO:0001558 Regulation of cell growth
Process GO:0001817 Regulation of cytokine production
Process GO:0001819 Positive regulation of cytokine production
Process GO:0001910 Regulation of leukocyte mediated cytotoxicity
Process GO:0001912 Positive regulation of leukocyte mediated cytotoxicity
Process GO:0001914 Regulation of T cell mediated cytotoxicity
Process GO:0001916 Positive regulation of T cell mediated cytotoxicity
Process GO:0001959 Regulation of cytokine-mediated signaling pathway
Process GO:0001961 Positive regulation of cytokine-mediated signaling pathway
Process GO:0002682 Regulation of immune system process
Process GO:0002684 Positive regulation of immune system process
Process GO:0002697 Regulation of immune effector process
Process GO:0002699 Positive regulation of immune effector process
Process GO:0002703 Regulation of leukocyte mediated immunity
Process GO:0002705 Positive regulation of leukocyte mediated immunity
Process GO:0002706 Regulation of lymphocyte mediated immunity
Process GO:0002708 Positive regulation of lymphocyte mediated immunity
Process GO:0002709 Regulation of T cell mediated immunity
Process GO:0002711 Positive regulation of T cell mediated immunity
Process GO:0002819 Regulation of adaptive immune response
Process GO:0002821 Positive regulation of adaptive immune response
Process GO:0002822 Regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
Process GO:0002824 Positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
Process GO:0002931 Response to ischemia
Process GO:0003008 System process
Process GO:0003013 Circulatory system process
Process GO:0003018 Vascular process in circulatory system
Process GO:0006139 Nucleobase-containing compound metabolic process
Process GO:0006163 Purine nucleotide metabolic process
Process GO:0006259 DNA metabolic process
Process GO:0006281 DNA repair
Process GO:0006355 Regulation of transcription, DNA-templated
Process GO:0006357 Regulation of transcription by RNA polymerase II
Process GO:0006401 RNA catabolic process
Process GO:0006402 mRNA catabolic process
Process GO:0006457 Protein folding
Process GO:0006458 De novo protein folding
Process GO:0006725 Cellular aromatic compound metabolic process
Process GO:0006753 Nucleoside phosphate metabolic process
Process GO:0006793 Phosphorus metabolic process
Process GO:0006796 Phosphate-containing compound metabolic process
Process GO:0006807 Nitrogen compound metabolic process
Process GO:0006810 Transport
Process GO:0006839 Mitochondrial transport
Process GO:0006950 Response to stress
Process GO:0006952 Defense response
Process GO:0006974 Cellular response to DNA damage stimulus
Process GO:0006986 Response to unfolded protein
Process GO:0006996 Organelle organization
Process GO:0007005 Mitochondrion organization
Process GO:0007006 Mitochondrial membrane organization
Process GO:0007034 Vacuolar transport
Process GO:0007041 Lysosomal transport
Process GO:0007275 Multicellular organism development
Process GO:0007338 Single fertilization
Process GO:0007339 Binding of sperm to zona pellucida
Process GO:0007399 Nervous system development
Process GO:0008015 Blood circulation
Process GO:0008037 Cell recognition
Process GO:0008152 Metabolic process
Process GO:0008285 Negative regulation of cell population proliferation
Process GO:0009056 Catabolic process
Process GO:0009057 Macromolecule catabolic process
Process GO:0009117 Nucleotide metabolic process
Process GO:0009141 Nucleoside triphosphate metabolic process
Process GO:0009144 Purine nucleoside triphosphate metabolic process
Process GO:0009150 Purine ribonucleotide metabolic process
Process GO:0009199 Ribonucleoside triphosphate metabolic process
Process GO:0009205 Purine ribonucleoside triphosphate metabolic process
Process GO:0009259 Ribonucleotide metabolic process
Process GO:0009266 Response to temperature stimulus
Process GO:0009314 Response to radiation
Process GO:0009408 Response to heat
Process GO:0009566 Fertilization
Process GO:0009605 Response to external stimulus
Process GO:0009612 Response to mechanical stimulus
Process GO:0009628 Response to abiotic stimulus
Process GO:0009889 Regulation of biosynthetic process
Process GO:0009890 Negative regulation of biosynthetic process
Process GO:0009892 Negative regulation of metabolic process
Process GO:0009893 Positive regulation of metabolic process
Process GO:0009894 Regulation of catabolic process
Process GO:0009896 Positive regulation of catabolic process
Process GO:0009966 Regulation of signal transduction
Process GO:0009967 Positive regulation of signal transduction
Process GO:0009968 Negative regulation of signal transduction
Process GO:0009987 Cellular process
Process GO:0009988 Cell-cell recognition
Process GO:0010033 Response to organic substance
Process GO:0010286 Heat acclimation
Process GO:0010466 Negative regulation of peptidase activity
Process GO:0010468 Regulation of gene expression
Process GO:0010556 Regulation of macromolecule biosynthetic process
Process GO:0010558 Negative regulation of macromolecule biosynthetic process
Process GO:0010564 Regulation of cell cycle process
Process GO:0010604 Positive regulation of macromolecule metabolic process
Process GO:0010605 Negative regulation of macromolecule metabolic process
Process GO:0010628 Positive regulation of gene expression
Process GO:0010629 Negative regulation of gene expression
Process GO:0010638 Positive regulation of organelle organization
Process GO:0010639 Negative regulation of organelle organization
Process GO:0010646 Regulation of cell communication
Process GO:0010647 Positive regulation of cell communication
Process GO:0010648 Negative regulation of cell communication
Process GO:0010803 Regulation of tumor necrosis factor-mediated signaling pathway
Process GO:0010821 Regulation of mitochondrion organization
Process GO:0010823 Negative regulation of mitochondrion organization
Process GO:0010941 Regulation of cell death
Process GO:0010951 Negative regulation of endopeptidase activity
Process GO:0010968 Regulation of microtubule nucleation
Process GO:0016043 Cellular component organization
Process GO:0016070 RNA metabolic process
Process GO:0016071 mRNA metabolic process
Process GO:0016192 Vesicle-mediated transport
Process GO:0017015 Regulation of transforming growth factor beta receptor signaling pathway
Process GO:0019219 Regulation of nucleobase-containing compound metabolic process
Process GO:0019222 Regulation of metabolic process
Process GO:0019229 Regulation of vasoconstriction
Process GO:0019439 Aromatic compound catabolic process
Process GO:0019637 Organophosphate metabolic process
Process GO:0019693 Ribose phosphate metabolic process
Process GO:0019953 Sexual reproduction
Process GO:0022008 Neurogenesis
Process GO:0022414 Reproductive process
Process GO:0022607 Cellular component assembly
Process GO:0023051 Regulation of signaling
Process GO:0023056 Positive regulation of signaling
Process GO:0023057 Negative regulation of signaling
Process GO:0030154 Cell differentiation
Process GO:0030162 Regulation of proteolysis
Process GO:0030182 Neuron differentiation
Process GO:0030308 Negative regulation of cell growth
Process GO:0030512 Negative regulation of transforming growth factor beta receptor signaling pathway
Process GO:0031110 Regulation of microtubule polymerization or depolymerization
Process GO:0031112 Positive regulation of microtubule polymerization or depolymerization
Process GO:0031113 Regulation of microtubule polymerization
Process GO:0031116 Positive regulation of microtubule polymerization
Process GO:0031323 Regulation of cellular metabolic process
Process GO:0031324 Negative regulation of cellular metabolic process
Process GO:0031325 Positive regulation of cellular metabolic process
Process GO:0031326 Regulation of cellular biosynthetic process
Process GO:0031327 Negative regulation of cellular biosynthetic process
Process GO:0031329 Regulation of cellular catabolic process
Process GO:0031331 Positive regulation of cellular catabolic process
Process GO:0031334 Positive regulation of protein-containing complex assembly
Process GO:0031341 Regulation of cell killing
Process GO:0031343 Positive regulation of cell killing
Process GO:0031396 Regulation of protein ubiquitination
Process GO:0031397 Negative regulation of protein ubiquitination
Process GO:0031399 Regulation of protein modification process
Process GO:0031400 Negative regulation of protein modification process
Process GO:0031647 Regulation of protein stability
Process GO:0032069 Regulation of nuclease activity
Process GO:0032075 Positive regulation of nuclease activity
Process GO:0032200 Telomere organization
Process GO:0032271 Regulation of protein polymerization
Process GO:0032273 Positive regulation of protein polymerization
Process GO:0032434 Regulation of proteasomal ubiquitin-dependent protein catabolic process
Process GO:0032436 Positive regulation of proteasomal ubiquitin-dependent protein catabolic process
Process GO:0032501 Multicellular organismal process
Process GO:0032502 Developmental process
Process GO:0032677 Regulation of interleukin-8 production
Process GO:0032757 Positive regulation of interleukin-8 production
Process GO:0032879 Regulation of localization
Process GO:0032886 Regulation of microtubule-based process
Process GO:0033043 Regulation of organelle organization
Process GO:0033120 Positive regulation of RNA splicing
Process GO:0033554 Cellular response to stress
Process GO:0034605 Cellular response to heat
Process GO:0034620 Cellular response to unfolded protein
Process GO:0034641 Cellular nitrogen compound metabolic process
Process GO:0034655 Nucleobase-containing compound catabolic process
Process GO:0035036 Sperm-egg recognition
Process GO:0035150 Regulation of tube size
Process GO:0035296 Regulation of tube diameter
Process GO:0035795 Negative regulation of mitochondrial membrane permeability
Process GO:0035966 Response to topologically incorrect protein
Process GO:0035967 Cellular response to topologically incorrect protein
Process GO:0040008 Regulation of growth
Process GO:0042026 Protein refolding
Process GO:0042127 Regulation of cell population proliferation
Process GO:0042176 Regulation of protein catabolic process
Process GO:0042221 Response to chemical
Process GO:0042981 Regulation of apoptotic process
Process GO:0043066 Negative regulation of apoptotic process
Process GO:0043067 Regulation of programmed cell death
Process GO:0043069 Negative regulation of programmed cell death
Process GO:0043085 Positive regulation of catalytic activity
Process GO:0043086 Negative regulation of catalytic activity
Process GO:0043154 Negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
Process GO:0043170 Macromolecule metabolic process
Process GO:0043254 Regulation of protein-containing complex assembly
Process GO:0043281 Regulation of cysteine-type endopeptidase activity involved in apoptotic process
Process GO:0043484 Regulation of RNA splicing
Process GO:0043618 Regulation of transcription from RNA polymerase II promoter in response to stress
Process GO:0043620 Regulation of DNA-templated transcription in response to stress
Process GO:0043933 Protein-containing complex organization
Process GO:0044057 Regulation of system process
Process GO:0044085 Cellular component biogenesis
Process GO:0044087 Regulation of cellular component biogenesis
Process GO:0044089 Positive regulation of cellular component biogenesis
Process GO:0044092 Negative regulation of molecular function
Process GO:0044093 Positive regulation of molecular function
Process GO:0044237 Cellular metabolic process
Process GO:0044238 Primary metabolic process
Process GO:0044248 Cellular catabolic process
Process GO:0044260 Cellular macromolecule metabolic process
Process GO:0044265 Cellular macromolecule catabolic process
Process GO:0044270 Cellular nitrogen compound catabolic process
Process GO:0044281 Small molecule metabolic process
Process GO:0045471 Response to ethanol
Process GO:0045595 Regulation of cell differentiation
Process GO:0045597 Positive regulation of cell differentiation
Process GO:0045637 Regulation of myeloid cell differentiation
Process GO:0045639 Positive regulation of myeloid cell differentiation
Process GO:0045646 Regulation of erythrocyte differentiation
Process GO:0045648 Positive regulation of erythrocyte differentiation
Process GO:0045664 Regulation of neuron differentiation
Process GO:0045666 Positive regulation of neuron differentiation
Process GO:0045732 Positive regulation of protein catabolic process
Process GO:0045861 Negative regulation of proteolysis
Process GO:0045862 Positive regulation of proteolysis
Process GO:0045892 Negative regulation of transcription, DNA-templated
Process GO:0045906 Negative regulation of vasoconstriction
Process GO:0045926 Negative regulation of growth
Process GO:0045934 Negative regulation of nucleobase-containing compound metabolic process
Process GO:0045935 Positive regulation of nucleobase-containing compound metabolic process
Process GO:0046034 ATP metabolic process
Process GO:0046483 Heterocycle metabolic process
Process GO:0046700 Heterocycle catabolic process
Process GO:0046902 Regulation of mitochondrial membrane permeability
Process GO:0046907 Intracellular transport
Process GO:0048518 Positive regulation of biological process
Process GO:0048519 Negative regulation of biological process
Process GO:0048522 Positive regulation of cellular process
Process GO:0048523 Negative regulation of cellular process
Process GO:0048583 Regulation of response to stimulus
Process GO:0048584 Positive regulation of response to stimulus
Process GO:0048585 Negative regulation of response to stimulus
Process GO:0048699 Generation of neurons
Process GO:0048731 System development
Process GO:0048856 Anatomical structure development
Process GO:0048869 Cellular developmental process
Process GO:0050776 Regulation of immune response
Process GO:0050778 Positive regulation of immune response
Process GO:0050789 Regulation of biological process
Process GO:0050790 Regulation of catalytic activity
Process GO:0050793 Regulation of developmental process
Process GO:0050794 Regulation of cellular process
Process GO:0050821 Protein stabilization
Process GO:0050896 Response to stimulus
Process GO:0051049 Regulation of transport
Process GO:0051084 De novo post-translational protein folding
Process GO:0051085 Chaperone cofactor-dependent protein refolding
Process GO:0051090 Regulation of DNA-binding transcription factor activity
Process GO:0051091 Positive regulation of DNA-binding transcription factor activity
Process GO:0051092 Positive regulation of NF-kappaB transcription factor activity
Process GO:0051094 Positive regulation of developmental process
Process GO:0051128 Regulation of cellular component organization
Process GO:0051129 Negative regulation of cellular component organization
Process GO:0051130 Positive regulation of cellular component organization
Process GO:0051131 Chaperone-mediated protein complex assembly
Process GO:0051171 Regulation of nitrogen compound metabolic process
Process GO:0051172 Negative regulation of nitrogen compound metabolic process
Process GO:0051173 Positive regulation of nitrogen compound metabolic process
Process GO:0051179 Localization
Process GO:0051234 Establishment of localization
Process GO:0051239 Regulation of multicellular organismal process
Process GO:0051240 Positive regulation of multicellular organismal process
Process GO:0051241 Negative regulation of multicellular organismal process
Process GO:0051246 Regulation of protein metabolic process
Process GO:0051247 Positive regulation of protein metabolic process
Process GO:0051248 Negative regulation of protein metabolic process
Process GO:0051252 Regulation of RNA metabolic process
Process GO:0051253 Negative regulation of RNA metabolic process
Process GO:0051254 Positive regulation of RNA metabolic process
Process GO:0051276 Chromosome organization
Process GO:0051336 Regulation of hydrolase activity
Process GO:0051345 Positive regulation of hydrolase activity
Process GO:0051346 Negative regulation of hydrolase activity
Process GO:0051493 Regulation of cytoskeleton organization
Process GO:0051495 Positive regulation of cytoskeleton organization
Process GO:0051641 Cellular localization
Process GO:0051649 Establishment of localization in cell
Process GO:0051716 Cellular response to stimulus
Process GO:0051726 Regulation of cell cycle
Process GO:0052547 Regulation of peptidase activity
Process GO:0052548 Regulation of endopeptidase activity
Process GO:0055086 Nucleobase-containing small molecule metabolic process
Process GO:0060236 Regulation of mitotic spindle organization
Process GO:0060255 Regulation of macromolecule metabolic process
Process GO:0060548 Negative regulation of cell death
Process GO:0060699 Regulation of endoribonuclease activity
Process GO:0060700 Regulation of ribonuclease activity
Process GO:0060759 Regulation of response to cytokine stimulus
Process GO:0060760 Positive regulation of response to cytokine stimulus
Process GO:0061024 Membrane organization
Process GO:0061077 Chaperone-mediated protein folding
Process GO:0061136 Regulation of proteasomal protein catabolic process
Process GO:0062207 Regulation of pattern recognition receptor signaling pathway
Process GO:0062208 Positive regulation of pattern recognition receptor signaling pathway
Process GO:0065003 Protein-containing complex assembly
Process GO:0065007 Biological regulation
Process GO:0065008 Regulation of biological quality
Process GO:0065009 Regulation of molecular function
Process GO:0070370 Cellular heat acclimation
Process GO:0070424 Regulation of nucleotide-binding oligomerization domain containing signaling pathway
Process GO:0070426 Positive regulation of nucleotide-binding oligomerization domain containing signaling pathway
Process GO:0070432 Regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
Process GO:0070434 Positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
Process GO:0070507 Regulation of microtubule cytoskeleton organization
Process GO:0070887 Cellular response to chemical stimulus
Process GO:0071310 Cellular response to organic substance
Process GO:0071704 Organic substance metabolic process
Process GO:0071840 Cellular component organization or biogenesis
Process GO:0072521 Purine-containing compound metabolic process
Process GO:0080090 Regulation of primary metabolic process
Process GO:0080134 Regulation of response to stress
Process GO:0080135 Regulation of cellular response to stress
Process GO:0090063 Positive regulation of microtubule nucleation
Process GO:0090066 Regulation of anatomical structure size
Process GO:0090083 Regulation of inclusion body assembly
Process GO:0090084 Negative regulation of inclusion body assembly
Process GO:0090092 Regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
Process GO:0090101 Negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
Process GO:0090169 Regulation of spindle assembly
Process GO:0090224 Regulation of spindle organization
Process GO:0090287 Regulation of cellular response to growth factor stimulus
Process GO:0090304 Nucleic acid metabolic process
Process GO:0090559 Regulation of membrane permeability
Process GO:0097201 Negative regulation of transcription from RNA polymerase II promoter in response to stress
Process GO:0097305 Response to alcohol
Process GO:0097746 Blood vessel diameter maintenance
Process GO:1901028 Regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
Process GO:1901029 Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
Process GO:1901099 Negative regulation of signal transduction in absence of ligand
Process GO:1901135 Carbohydrate derivative metabolic process
Process GO:1901360 Organic cyclic compound metabolic process
Process GO:1901361 Organic cyclic compound catabolic process
Process GO:1901564 Organonitrogen compound metabolic process
Process GO:1901575 Organic substance catabolic process
Process GO:1901673 Regulation of mitotic spindle assembly
Process GO:1901700 Response to oxygen-containing compound
Process GO:1901800 Positive regulation of proteasomal protein catabolic process
Process GO:1902115 Regulation of organelle assembly
Process GO:1902235 Regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
Process GO:1902236 Negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
Process GO:1902380 Positive regulation of endoribonuclease activity
Process GO:1902531 Regulation of intracellular signal transduction
Process GO:1902532 Negative regulation of intracellular signal transduction
Process GO:1902533 Positive regulation of intracellular signal transduction
Process GO:1902679 Negative regulation of RNA biosynthetic process
Process GO:1902903 Regulation of supramolecular fiber organization
Process GO:1902905 Positive regulation of supramolecular fiber organization
Process GO:1903050 Regulation of proteolysis involved in protein catabolic process
Process GO:1903052 Positive regulation of proteolysis involved in protein catabolic process
Process GO:1903265 Positive regulation of tumor necrosis factor-mediated signaling pathway
Process GO:1903320 Regulation of protein modification by small protein conjugation or removal
Process GO:1903321 Negative regulation of protein modification by small protein conjugation or removal
Process GO:1903506 Regulation of nucleic acid-templated transcription
Process GO:1903507 Negative regulation of nucleic acid-templated transcription
Process GO:1903522 Regulation of blood circulation
Process GO:1903573 Negative regulation of response to endoplasmic reticulum stress
Process GO:1903706 Regulation of hemopoiesis
Process GO:1903844 Regulation of cellular response to transforming growth factor beta stimulus
Process GO:1905709 Negative regulation of membrane permeability
Process GO:1905897 Regulation of response to endoplasmic reticulum stress
Process GO:2000026 Regulation of multicellular organismal development
Process GO:2000058 Regulation of ubiquitin-dependent protein catabolic process
Process GO:2000060 Positive regulation of ubiquitin-dependent protein catabolic process
Process GO:2000116 Regulation of cysteine-type endopeptidase activity
Process GO:2000117 Negative regulation of cysteine-type endopeptidase activity
Process GO:2001141 Regulation of RNA biosynthetic process
Process GO:2001233 Regulation of apoptotic signaling pathway
Process GO:2001234 Negative regulation of apoptotic signaling pathway
Process GO:2001236 Regulation of extrinsic apoptotic signaling pathway
Process GO:2001237 Negative regulation of extrinsic apoptotic signaling pathway
Process GO:2001239 Regulation of extrinsic apoptotic signaling pathway in absence of ligand
Process GO:2001240 Negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
Process GO:2001242 Regulation of intrinsic apoptotic signaling pathway
Process GO:2001243 Negative regulation of intrinsic apoptotic signaling pathway
Component GO:0002199 Zona pellucida receptor complex
Component GO:0005576 Extracellular region
Component GO:0005622 Intracellular anatomical structure
Component GO:0005634 Nucleus
Component GO:0005654 Nucleoplasm
Component GO:0005737 Cytoplasm
Component GO:0005739 Mitochondrion
Component GO:0005813 Centrosome
Component GO:0005814 Centriole
Component GO:0005815 Microtubule organizing center
Component GO:0005829 Cytosol
Component GO:0005856 Cytoskeleton
Component GO:0005886 Plasma membrane
Component GO:0009925 Basal plasma membrane
Component GO:0015630 Microtubule cytoskeleton
Component GO:0016020 Membrane
Component GO:0016234 Inclusion body
Component GO:0016235 Aggresome
Component GO:0016323 Basolateral plasma membrane
Component GO:0016324 Apical plasma membrane
Component GO:0016604 Nuclear body
Component GO:0016607 Nuclear speck
Component GO:0031974 Membrane-enclosed lumen
Component GO:0031981 Nuclear lumen
Component GO:0032991 Protein-containing complex
Component GO:0043226 Organelle
Component GO:0043227 Membrane-bounded organelle
Component GO:0043228 Non-membrane-bounded organelle
Component GO:0043229 Intracellular organelle
Component GO:0043231 Intracellular membrane-bounded organelle
Component GO:0043232 Intracellular non-membrane-bounded organelle
Component GO:0043233 Organelle lumen
Component GO:0044297 Cell body
Component GO:0045121 Membrane raft
Component GO:0045177 Apical part of cell
Component GO:0045178 Basal part of cell
Component GO:0048471 Perinuclear region of cytoplasm
Component GO:0070013 Intracellular organelle lumen
Component GO:0071944 Cell periphery
Component GO:0098590 Plasma membrane region
Component GO:0098857 Membrane microdomain
Component GO:0110165 Cellular anatomical entity
Component GO:1990904 Ribonucleoprotein complex
Function GO:0000166 Nucleotide binding
Function GO:0001664 G protein-coupled receptor binding
Function GO:0002020 Protease binding
Function GO:0003712 Transcription coregulator activity
Function GO:0003714 Transcription corepressor activity
Function GO:0003824 Catalytic activity
Function GO:0005102 Signaling receptor binding
Function GO:0005488 Binding
Function GO:0005515 Protein binding
Function GO:0005524 ATP binding
Function GO:0008134 Transcription factor binding
Function GO:0016462 Pyrophosphatase activity
Function GO:0016787 Hydrolase activity
Function GO:0016817 Hydrolase activity, acting on acid anhydrides
Function GO:0016818 Hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
Function GO:0016887 ATP hydrolysis activity
Function GO:0017076 Purine nucleotide binding
Function GO:0017111 Nucleoside-triphosphatase activity
Function GO:0019899 Enzyme binding
Function GO:0019904 Protein domain specific binding
Function GO:0030554 Adenyl nucleotide binding
Function GO:0031072 Heat shock protein binding
Function GO:0031249 Denatured protein binding
Function GO:0031625 Ubiquitin protein ligase binding
Function GO:0032553 Ribonucleotide binding
Function GO:0032555 Purine ribonucleotide binding
Function GO:0032559 Adenyl ribonucleotide binding
Function GO:0035639 Purine ribonucleoside triphosphate binding
Function GO:0036094 Small molecule binding
Function GO:0042826 Histone deacetylase binding
Function GO:0043167 Ion binding
Function GO:0043168 Anion binding
Function GO:0044183 Protein folding chaperone
Function GO:0044389 Ubiquitin-like protein ligase binding
Function GO:0047485 Protein N-terminus binding
Function GO:0051059 NF-kappaB binding
Function GO:0051082 Unfolded protein binding
Function GO:0051787 Misfolded protein binding
Function GO:0055131 C3HC4-type RING finger domain binding
Function GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding
Function GO:0097159 Organic cyclic compound binding
Function GO:0097367 Carbohydrate derivative binding
Function GO:0097718 Disordered domain specific binding
Function GO:0140110 Transcription regulator activity
Function GO:0140297 DNA-binding transcription factor binding
Function GO:0140545 ATP-dependent protein disaggregase activity
Function GO:0140657 ATP-dependent activity
Function GO:0140662 ATP-dependent protein folding chaperone
Function GO:0140776 Protein-containing complex destabilizing activity
Function GO:1901265 Nucleoside phosphate binding
Function GO:1901363 Heterocyclic compound binding

Pathway annotation


Category Term ID Term description
RCTM RNO-168249 Innate Immune System
RCTM RNO-168256 Immune System
RCTM RNO-2262752 Cellular responses to stress
RCTM RNO-3371453 Regulation of HSF1-mediated heat shock response
RCTM RNO-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
RCTM RNO-3371556 Cellular response to heat stress
RCTM RNO-3371568 Attenuation phase
RCTM RNO-3371571 HSF1-dependent transactivation
RCTM RNO-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA
RCTM RNO-450531 Regulation of mRNA stability by proteins that bind AU-rich elements
RCTM RNO-6798695 Neutrophil degranulation
RCTM RNO-8953854 Metabolism of RNA
RCTM RNO-8953897 Cellular responses to stimuli
WikiPathways WP487 Apoptosis modulation by HSP70
WikiPathways WP590 Cardiovascular signaling

Expression profile of Hspa1a in omics data



ID GSE138454
Title Impact of inflammation on hepatic subcellular energetics in anesthetized rats
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM4108997 Sample 1 Isoflurane sepsis anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 0.0
GSM4108998 Sample 2 Isoflurane sepsis anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 0.0
GSM4108999 Sample 3 Isoflurane sepsis anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 0.0
GSM4109000 Sample 4 Isoflurane sepsis anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 0.0
GSM4109001 Sample 5 Isoflurane control anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 0.0
GSM4109002 Sample 6 Isoflurane control anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 0.0
GSM4109003 Sample 7 Isoflurane control anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 0.0
GSM4109004 Sample 8 Isoflurane control anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 0.0
GSM4109005 Sample9 Propofol sepsis anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 0.0
GSM4109006 Sample10 Propofol sepsis anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 0.0
GSM4109007 Sample11 Propofol sepsis anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 0.0
GSM4109008 Sample12 Propofol sepsis anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 0.0
GSM4109009 Sample13 Propofol control anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 0.0
GSM4109010 Sample14 Propofol control anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 0.0
GSM4109011 Sample 15 Propofol control anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 0.0
GSM4109012 Sample16 Propofol control anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 0.0

ID GSE139220
Title Expression data from sevoflurane anesthesia treated rat
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM4134285 Brain_Control_rep1 strain: Sprague-Dawley age: 18-month old treatment: control tissue: hippocampus 5.259378
GSM4134286 Brain_Control_rep2 strain: Sprague-Dawley age: 18-month old treatment: control tissue: hippocampus 5.2910895
GSM4134287 Brain_Control_rep3 strain: Sprague-Dawley age: 18-month old treatment: control tissue: hippocampus 5.1735925
GSM4134288 Brain_Sevoflurane_rep1 strain: Sprague-Dawley age: 18-month old treatment: sevoflurane anesthesia tissue: hippocampus 5.458795
GSM4134289 Brain_Sevoflurane_rep2 strain: Sprague-Dawley age: 18-month old treatment: sevoflurane anesthesia tissue: hippocampus 5.248908
GSM4134290 Brain_Sevoflurane_rep3 strain: Sprague-Dawley age: 18-month old treatment: sevoflurane anesthesia tissue: hippocampus 5.12542

ID GSE143895
Title GPR160 de-orphanization reveals critical roles in neuropathic pain in rodents
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM4276356 dhsc01 strain: Sprague Dawley tissue: DHSC treatment: CCI 0.403
GSM4276357 dhsc03 strain: Sprague Dawley tissue: DHSC treatment: CCI 0.515
GSM4276358 dhsc05 strain: Sprague Dawley tissue: DHSC treatment: CCI 0.757
GSM4276359 dhsc13 strain: Sprague Dawley tissue: DHSC treatment: SHAM 0.749
GSM4276360 dhsc15 strain: Sprague Dawley tissue: DHSC treatment: SHAM 0.508

ID GSE157924
Title Regulation of acupuncture on genes in brain stem
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM4780973 Rattus_JSSZ(Sham) tissue: Rattus brainstem of modeling treatment: Sham 7.4508602669999995
GSM4780974 Rattus_JXZ(Hand Acu) tissue: Rattus brainstem of modeling treatment: Hand Acu 7.5949137865
GSM4780975 Rattus_MXZ(TBI) tissue: Rattus brainstem of modeling treatment: TBI 7.5468631955

ID GSE1616
Title Genomics of preconditioning
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM27484 APC_a (anesthetic-preconditioning, 1st replicate) 19722.4
GSM27485 APC_b (anesthetic-preconditioning, 2nd replicate) 20818.9
GSM27486 APC_c (anesthetic-preconditioning, 3rd replicate) 13739.5
GSM27487 APC_d (anesthetic-preconditioning, 4th replicate) 14611.7
GSM27488 APC_e (anesthetic-preconditioning, 5th replicate) 14589.4
GSM27489 APC_TRI_a (trigger of anesthetic-preconditioning, 1st replicate) 1245.3
GSM27490 APC_TRI_b (trigger of anesthetic-preconditioning, 2nd replicate) 2168.5
GSM27491 APC_TRI_c (trigger of anesthetic-preconditioning, 3rd replicate) 2450.3
GSM27492 APC_TRI_d (trigger of anesthetic-preconditioning, 4th replicate) 1992.0
GSM27493 APC_TRI_e (trigger of anesthetic-preconditioning, 5th replicate) 2609.7
GSM27494 CTL_a (control, 1st replicate) 2363.4
GSM27495 CTL_b (control, 2nd replicate) 4667.7
GSM27496 CTL_c (control, 3rd replicate) 10208.1
GSM27497 CTL_d (control, 4th replicate) 4622.8
GSM27498 CTL_e (control, 5th replicate) 4991.7
GSM27499 IPC_a (ischemic preconditioning, 1st replicate) 17066.6
GSM27500 IPC_b (ischemic preconditioning, 2nd replicate) 17247.3
GSM27501 IPC_c (ischemic preconditioning, 3rd replicate) 14828.0
GSM27502 IPC_d (ischemic preconditioning, 4th replicate) 19380.2
GSM27503 IPC_e (ischemic preconditioning, 5th replicate) 16567.5
GSM27504 IPC_TRI_a (trigger of ischemic preconditioning, 1st replicate) 7063.9
GSM27505 IPC_TRI_b (trigger of ischemic preconditioning, 2nd replicate) 5261.1
GSM27506 IPC_TRI_c (trigger of ischemic preconditioning, 3rd replicate) 7305.5
GSM27507 IPC_TRI_d (trigger of ischemic preconditioning, 4th replicate) 4960.4
GSM27508 IPC_TRI_e (trigger of ischemic preconditioning, 5th replicate) 1407.3
GSM27509 ISCH_a (ischemia, 1st replicate) 25032.9
GSM27510 ISCH_b (ischemia, 2nd replicate) 24667.0
GSM27511 ISCH_c (ischemia, 3rd replicate) 27806.3
GSM27512 ISCH_d (ischemia, 4th replicate) 24256.6
GSM27513 ISCH_e (ischemia, 5th replicate) 14602.2

ID GSE1779
Title Effect of Isoflurane and LTM on basolateral amygdala
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM30790 baseline control 01 male, 275-300g 328.4
GSM30791 baseline control 02 male, 275-300g 311.0
GSM30792 baseline control 03 male, 275-300g 259.4
GSM30793 baseline control 04 male, 275-300g 211.0
GSM30794 baseline control 05 male, 275-300g 270.2
GSM30795 baseline control 06 male, 275-300g 173.9
GSM30796 baseline control 07 male, 275-300g 191.9
GSM30797 baseline control 08 male, 275-300g 209.3
GSM30798 baseline control 09 male, 275-300g 207.1
GSM30799 pain 01 301.7
GSM30800 pain 02 339.7
GSM30801 pain 03 335.0
GSM30802 pain 04 186.9
GSM30803 pain 05 263.9
GSM30804 FC 01 270.9
GSM30805 FC 02 223.4
GSM30806 FC 03 214.9
GSM30807 FC 04 274.7
GSM30808 FC 05 265.7
GSM30809 IFC 01 267.0
GSM30810 IFC 02 240.4
GSM30811 IFC 03 230.5
GSM30812 IFC 04 160.9
GSM30813 IFC 05 253.7
GSM99800 isoflurane 01 male, 275-300g 204.3
GSM99801 isoflurane 02 male, 275-300g 321.2
GSM99802 isoflurane 03 male, 275-300g 319.3
GSM99803 isoflurane 04 male, 275-300g 238.3
GSM99804 isoflurane 05 male, 275-300g 277.1

ID GSE190472
Title Study on VEGF regulation mechanism of acupuncture improving endometrial receptivity in IVF-ET
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM5724271 model 21 Sex: female tissue: Uterine tissue condition: model 483.458
GSM5724272 model 22 Sex: female tissue: Uterine tissue condition: model 430.50975000000005
GSM5724273 model 23 Sex: female tissue: Uterine tissue condition: model 461.30885
GSM5724274 treatment31 Sex: female tissue: Uterine tissue condition: treatment 530.35605
GSM5724275 treatment32 Sex: female tissue: Uterine tissue condition: treatment 679.115
GSM5724276 treatment33 Sex: female tissue: Uterine tissue condition: treatment 385.69725
GSM5724277 control 41 Sex: female tissue: Uterine tissue condition: control 318.5232
GSM5724278 control 42 Sex: female tissue: Uterine tissue condition: control 557.52865
GSM5724279 control 43 Sex: female tissue: Uterine tissue condition: control 227.06735

ID GSE192399
Title Gene expression of brain regions activated by sevoflurane and propofol
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM5746332 LHb, Sevoflurane, 60mins brain region: the lateral habenula (LHb) treatment: Sevoflurane 5.15412
GSM5746333 LHb, O2, 60mins brain region: the lateral habenula (LHb) treatment: O2 4.80057
GSM5746334 MHb, Sevoflurane, 60mins brain region: the medial habenula (MHb) treatment: Sevoflurane 4.93741
GSM5746335 MHb, O2, 60mins brain region: the medial habenula (MHb) treatment: O2 4.24034
GSM5746336 Sol, Sevoflurane, 60mins brain region: the solitary nucleus (Sol) treatment: Sevoflurane 4.79045
GSM5746337 Sol, O2, 60mins brain region: the solitary nucleus (Sol) treatment: O2 5.50732
GSM5746338 Mve, Sevoflurane, 60mins brain region: the medial vestibular nucleus (MVe) treatment: Sevoflurane 4.73182
GSM5746339 Mve, O2, 60mins brain region: the medial vestibular nucleus (MVe) treatment: O2 5.50132
GSM5746340 LHb, Propofol, 60mins brain region: the lateral habenula (LHb) treatment: Propofol 4.83259
GSM5746341 LHb, Intralipos, 60mins brain region: the lateral habenula (LHb) treatment: Intralipos 6.09465
GSM5746342 MHb, Propofol, 60mins brain region: the medial habenula (MHb) treatment: Propofol 4.32627
GSM5746343 MHb, Intralipos, 60mins brain region: the medial habenula (MHb) treatment: Intralipos 4.55397
GSM5746344 Sol, Propofol, 60mins brain region: the solitary nucleus (Sol) treatment: Propofol 4.67067
GSM5746345 Sol, Intralipos, 60mins brain region: the solitary nucleus (Sol) treatment: Intralipos 5.0793
GSM5746346 MVe, Propofol, 60mins brain region: the medial vestibular nucleus (MVe) treatment: Propofol 4.36813
GSM5746347 MVe, Intralipos, 60mins brain region: the medial vestibular nucleus (MVe) treatment: Intralipos 5.05225

ID GSE232804
Title EGR3 regulates opioid-related nociception and motivation in male rats
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM7383519 ww01_Saline_Saline tissue: Brain / mPFC pain: Saline drug: Salin 8.0
GSM7383520 ww02_Saline_Saline tissue: Brain / mPFC pain: Saline drug: Saline 5.0
GSM7383521 ww03_Saline_Saline tissue: Brain / mPFC pain: Saline drug: Salin 5.0
GSM7383522 ww05_Saline_Saline tissue: Brain / mPFC pain: Saline drug: Saline 7.0
GSM7383523 ww06_Saline_Saline tissue: Brain / mPFC pain: Saline drug: Salin 10.0
GSM7383524 ww07_Saline_Saline tissue: Brain / mPFC pain: Saline drug: Saline 7.0
GSM7383525 ww08_Saline_Saline tissue: Brain / mPFC pain: Saline drug: Salin 7.0
GSM7383526 ww10_Saline_Saline tissue: Brain / mPFC pain: Saline drug: Saline 6.0
GSM7383527 ww12_Saline_OXY tissue: Brain / mPFC pain: Saline drug: OXY 9.0
GSM7383528 ww13_Saline_OXY tissue: Brain / mPFC pain: Saline drug: OXY 17.0
GSM7383529 ww14_Saline_OXY tissue: Brain / mPFC pain: Saline drug: OXY 37.0
GSM7383530 ww15_Saline_OXY tissue: Brain / mPFC pain: Saline drug: OXY 19.0
GSM7383531 ww16_Saline_OXY tissue: Brain / mPFC pain: Saline drug: OXY 5.0
GSM7383532 ww17_Saline_OXY tissue: Brain / mPFC pain: Saline drug: OXY 21.0
GSM7383533 ww18_Saline_OXY tissue: Brain / mPFC pain: Saline drug: OXY 21.0
GSM7383534 ww20_Saline_OXY tissue: Brain / mPFC pain: Saline drug: OXY 22.0
GSM7383535 ww21_CFA_Saline tissue: Brain / mPFC pain: CFA drug: Saline 9.0
GSM7383536 ww22_CFA_Saline tissue: Brain / mPFC pain: CFA drug: Saline 10.0
GSM7383537 ww23_CFA_Saline tissue: Brain / mPFC pain: CFA drug: Saline 1.0
GSM7383538 ww24_CFA_Saline tissue: Brain / mPFC pain: CFA drug: Saline 4.0
GSM7383539 ww26_CFA_Saline tissue: Brain / mPFC pain: CFA drug: Saline 6.0
GSM7383540 ww27_CFA_Saline tissue: Brain / mPFC pain: CFA drug: Saline 12.0
GSM7383541 ww28_CFA_Saline tissue: Brain / mPFC pain: CFA drug: Saline 5.0
GSM7383542 ww30_CFA_Saline tissue: Brain / mPFC pain: CFA drug: Saline 4.0
GSM7383543 ww31_CFA_OXY tissue: Brain / mPFC pain: CFA drug: OXY 33.0
GSM7383544 ww32_CFA_OXY tissue: Brain / mPFC pain: CFA drug: OXY 16.0
GSM7383545 ww34_CFA_OXY tissue: Brain / mPFC pain: CFA drug: OXY 61.0
GSM7383546 ww35_CFA_OXY tissue: Brain / mPFC pain: CFA drug: OXY 31.0
GSM7383547 ww36_CFA_OXY tissue: Brain / mPFC pain: CFA drug: OXY 26.0
GSM7383548 ww37_CFA_OXY tissue: Brain / mPFC pain: CFA drug: OXY 10.0
GSM7383549 ww38_CFA_OXY tissue: Brain / mPFC pain: CFA drug: OXY 8.0
GSM7383550 www09_Saline_Saline tissue: Brain / mPFC pain: Saline drug: Saline 4.0
GSM7383551 www19_Saline_OXY tissue: Brain / mPFC pain: Saline drug: OXY 43.0
GSM7383552 www29_CFA_Saline tissue: Brain / mPFC pain: CFA drug: Saline 4.0
GSM7383553 www33_CFA_OXY tissue: Brain / mPFC pain: CFA drug: OXY 25.0
GSM7383554 www39_CFA_OXY tissue: Brain / mPFC pain: CFA drug: OXY 4.0

ID GSE244436
Title Similarity and dissimilarity in alteration of gene expression profile associated with inhalational anesthesia between sevoflurane and desflurane
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM7816143 Liver, Control for SevoAnes tissue: liver genotype: wild type treatment: Control for SevoAnes 0.027751
GSM7816144 Liver, Anesthetized with sevoflurane for 6 h tissue: liver genotype: wild type treatment: Anesthetized with sevoflurane for 6 h 0.512917
GSM7816145 Liver, Control for DesAnes tissue: liver genotype: wild type treatment: Control for DesAnes 0.060919
GSM7816146 Liver, Anesthetized with desflurane for 6 h tissue: liver genotype: wild type treatment: Anesthetized with desflurane for 6 h 0.24749

ID GSE2982
Title Effect of inhaled anesthetic to cultured cortical neurons
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM61779 Cell Culture Exposure (control1) Cy3 label;Cy5; 0.0681
GSM61796 Cell Culture Exposure (control2) Cy3; Cy5 -0.0778
GSM61797 Cell Culture Exposure (control3) Cy3; Cy5 0.0988
GSM61798 Cell Culture Exposure (1MAC Halo1) Cy3; Cy5 -0.00401
GSM61799 Cell Culture Exposure (1MAC Halo2) Cy3; Cy5 0.1
GSM61800 Cell Culture Exposure (1MAC Halo3) Cy3; Cy5 0.116
GSM61801 Cell Culture Exposure (3MAC Halo1) Cy3; Cy5 -0.0293
GSM61802 Cell Culture Exposure (3MAC Halo2) Cy3; Cy5 -0.0376
GSM61803 Cell Culture Exposure (3MAC Halo3) Cy3; Cy5 -0.0243
GSM61804 Cell Culture Exposure (3MAC ISO1) Cy3; Cy5 0.188
GSM61805 Cell Culture Exposure (3MAC ISO2) Cy3; Cy5 0.0401
GSM61806 Cell Culture Exposure (3MAC ISO3) Cy3; Cy5 0.112

ID GSE359
Title Isoflurane Single Exposures
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM5120 Isoflurane single exposure control-1 32.4
GSM5121 Isoflurane single exposure control-2 55.8
GSM5122 Isoflurane single exposure control-3 10.7
GSM5124 Isoflurane single exposure 1 hr-1 54.6
GSM5126 Isoflurane single exposure 1 hr-2 16.0
GSM5127 Isoflurane single exposure 2 hr-1 57.0
GSM5130 Isoflurane single exposure 2 hr-2 47.0
GSM5131 Isoflurane single exposure 2 hr-3 28.1

ID GSE48025
Title Affymetrix Chip Data of the Transcriptome of the Rheumatoid Arthritis Rat Model Treated with Acupuncture (Affymetrix, mRNA, batch1)
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM1165929 RAT_NORA_T0_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats before therapy 5.491497333
GSM1165930 RAT_NORA_T0_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats before therapy 5.6471242749999995
GSM1165931 RAT_RA_T0_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats before therapy 5.14575245875
GSM1165932 RAT_RA_T0_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats before therapy 5.239439614
GSM1165933 RAT_NORA_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 1 hour after therapy 5.5160844542500005
GSM1165934 RAT_NORA_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 1 hour after therapy 5.262785886750001
GSM1165935 RAT_AP_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour acupuncture therapy 5.448961387500001
GSM1165936 RAT_AP_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour acupuncture therapy 4.9989793237499995
GSM1165937 RAT_MTX_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour MTX therapy 5.337530077749999
GSM1165938 RAT_MTX_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour MTX therapy 5.07527876425
GSM1165939 RAT_ANE_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour ANE therapy 5.751503989250001
GSM1165940 RAT_ANE_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour ANE therapy 5.4152783105
GSM1165941 RAT_PLA_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour placebo therapy 5.257232464
GSM1165942 RAT_PLA_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour placebo therapy 5.58591553625
GSM1165943 RAT_NORA_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 34 days after therapy 5.2147423495
GSM1165944 RAT_NORA_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 34 days after therapy 5.42704042375
GSM1165945 RAT_AP_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days acupuncture therapy 5.3573654694999995
GSM1165946 RAT_AP_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days acupuncture therapy 5.01430937475
GSM1165947 RAT_MTX_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days MTX therapy 5.4478649597499995
GSM1165948 RAT_MTX_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days MTX therapy 5.33932810825
GSM1165949 RAT_ANE_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days ANE therapy 5.630683753
GSM1165950 RAT_ANE_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days ANE therapy 5.68200688425
GSM1165951 RAT_PLA_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days placebo therapy 5.1393755505000005
GSM1165952 RAT_PLA_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days placebo therapy 5.08770893225

ID GSE58456
Title Affymetrix Chip Data of the Transcriptome of the Rheumatoid Arthritis Rat Model Treated with Acupuncture (Affymetrix, mRNA, batch 2)
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM1693996 Peripheral blood mononuclear cells from NORA before therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats before therapy 129.95223585
GSM1693997 Peripheral blood mononuclear cells from NORA before therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats before therapy 105.43395720000001
GSM1693998 Peripheral blood mononuclear cells from NORA before therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats before therapy 204.016602425
GSM1693999 Peripheral blood mononuclear cells from RA before therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats before therapy 77.88348783
GSM1694000 Peripheral blood mononuclear cells from RA before therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats before therapy 98.3926301525
GSM1694001 Peripheral blood mononuclear cells from HAP after 34 days acupuncture therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats after 34 days acupuncture therapy 234.4652904
GSM1694002 Peripheral blood mononuclear cells from HAP after 34 days acupuncture therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats after 34 days acupuncture therapy 147.05473497499997
GSM1694003 Peripheral blood mononuclear cells from HAP after 34 days acupuncture therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats after 34 days acupuncture therapy 244.481604225
GSM1694004 Peripheral blood mononuclear cells from AP after 34 days acupuncture therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days acupuncture therapy 158.63496495
GSM1694005 Peripheral blood mononuclear cells from AP after 34 days acupuncture therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days acupuncture therapy 425.31610939999996
GSM1694006 Peripheral blood mononuclear cells from AP after 34 days acupuncture therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days acupuncture therapy 166.59274255
GSM1694007 Peripheral blood mononuclear cells from MTXAP after 34 days MTX&acupuncture therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days methotrexate & acupuncture therapy 149.2776879
GSM1694008 Peripheral blood mononuclear cells from MTXAP after 34 days MTX&acupuncture therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days methotrexate & acupuncture therapy 104.67748828250001
GSM1694009 Peripheral blood mononuclear cells from MTXAP after 34 days MTX&acupuncture therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days methotrexate & acupuncture therapy 258.91075595

ID GSE58460
Title Rheumatoid Arthritis Rat Model Treated with Acupuncture
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM1165929 RAT_NORA_T0_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats before therapy 5.491497333
GSM1165930 RAT_NORA_T0_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats before therapy 5.6471242749999995
GSM1165931 RAT_RA_T0_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats before therapy 5.14575245875
GSM1165932 RAT_RA_T0_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats before therapy 5.239439614
GSM1165933 RAT_NORA_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 1 hour after therapy 5.5160844542500005
GSM1165934 RAT_NORA_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 1 hour after therapy 5.262785886750001
GSM1165935 RAT_AP_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour acupuncture therapy 5.448961387500001
GSM1165936 RAT_AP_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour acupuncture therapy 4.9989793237499995
GSM1165937 RAT_MTX_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour MTX therapy 5.337530077749999
GSM1165938 RAT_MTX_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour MTX therapy 5.07527876425
GSM1165939 RAT_ANE_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour ANE therapy 5.751503989250001
GSM1165940 RAT_ANE_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour ANE therapy 5.4152783105
GSM1165941 RAT_PLA_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour placebo therapy 5.257232464
GSM1165942 RAT_PLA_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour placebo therapy 5.58591553625
GSM1165943 RAT_NORA_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 34 days after therapy 5.2147423495
GSM1165944 RAT_NORA_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 34 days after therapy 5.42704042375
GSM1165945 RAT_AP_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days acupuncture therapy 5.3573654694999995
GSM1165946 RAT_AP_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days acupuncture therapy 5.01430937475
GSM1165947 RAT_MTX_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days MTX therapy 5.4478649597499995
GSM1165948 RAT_MTX_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days MTX therapy 5.33932810825
GSM1165949 RAT_ANE_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days ANE therapy 5.630683753
GSM1165950 RAT_ANE_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days ANE therapy 5.68200688425
GSM1165951 RAT_PLA_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days placebo therapy 5.1393755505000005
GSM1165952 RAT_PLA_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days placebo therapy 5.08770893225
GSM1412003 RAT_NORA_T0_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412004 RAT_NORA_T0_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412005 RAT_RA_T0_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412006 RAT_RA_T0_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412007 RAT_NORA_1h_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412008 RAT_NORA_1h_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412009 RAT_AP_1h_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412010 RAT_AP_1h_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412011 RAT_MTX_1h_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412012 RAT_MTX_1h_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412013 RAT_ANE_1h_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412014 RAT_ANE_1h_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412015 RAT_PLA_1h_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412016 RAT_PLA_1h_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412017 RAT_NORA_34d_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412018 RAT_NORA_34d_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412019 RAT_AP_34d_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412020 RAT_AP_34d_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412021 RAT_MTX_34d_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412022 RAT_MTX_34d_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412023 RAT_ANE_34d_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412024 RAT_ANE_34d_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412025 RAT_PLA_34d_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412026 RAT_PLA_34d_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412027 RAT_RA_T0_1 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412028 RAT_RA_T0_2 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412029 RAT_AP_1h_1 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412030 RAT_AP_1h_2 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412031 RAT_PLA_1h_1 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412032 RAT_PLA_1h_2 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412033 RAT_AP_34d_1 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412034 RAT_AP_34d_2 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412035 RAT_PLA_34d_1 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412036 RAT_PLA_34d_2 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1693996 Peripheral blood mononuclear cells from NORA before therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats before therap 129.95223585
GSM1693997 Peripheral blood mononuclear cells from NORA before therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats before therapy 105.43395720000001
GSM1693998 Peripheral blood mononuclear cells from NORA before therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats before therapy 204.016602425
GSM1693999 Peripheral blood mononuclear cells from RA before therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats before therapy 77.88348783
GSM1694000 Peripheral blood mononuclear cells from RA before therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats before therapy 98.3926301525
GSM1694001 Peripheral blood mononuclear cells from HAP after 34 days acupuncture therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats after 34 days acupuncture therapy 234.4652904
GSM1694002 Peripheral blood mononuclear cells from HAP after 34 days acupuncture therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats after 34 days acupuncture therap 147.05473497499997
GSM1694003 Peripheral blood mononuclear cells from HAP after 34 days acupuncture therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats after 34 days acupuncture therapy 244.481604225
GSM1694004 Peripheral blood mononuclear cells from AP after 34 days acupuncture therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days acupuncture therapy 158.63496495
GSM1694005 Peripheral blood mononuclear cells from AP after 34 days acupuncture therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days acupuncture therapy 425.31610939999996
GSM1694006 Peripheral blood mononuclear cells from AP after 34 days acupuncture therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days acupuncture therapy 166.59274255
GSM1694007 Peripheral blood mononuclear cells from MTXAP after 34 days MTX&acupuncture therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days methotrexate & acupuncture therapy 149.2776879
GSM1694008 Peripheral blood mononuclear cells from MTXAP after 34 days MTX&acupuncture therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days methotrexate & acupuncture therapy 104.67748828250001
GSM1694009 Peripheral blood mononuclear cells from MTXAP after 34 days MTX&acupuncture therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days methotrexate & acupuncture therapy 258.91075595

ID GSE752
Title Halothane/Isoflurane Repetitive Exposures
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM5082 Control 1 29.7
GSM5084 Control 2 34.2
GSM5085 Control 3 37.8
GSM5086 Control 4 47.9
GSM5087 Control 5 53.9
GSM5090 Control 6 40.7
GSM5105 Control 7 62.4
GSM5106 Control 8 35.3
GSM5107 Control 9 47.6
GSM5108 Halothane 10 exposure-1 25.8
GSM5109 Halothane 10 exposures-2 38.3
GSM5110 Halothane 10 exposures-3 48.4
GSM5111 Halothane 5 exposures-1 45.2
GSM5112 Halothane 5 exposures-2 34.5
GSM5113 Halothane 5 exposures-3 63.4
GSM5114 Isoflurane 10 exposures-1 29.5
GSM5115 Isoflurane 10 exposures-2 59.5
GSM5116 Isoflurane 10 exposures-3 37.8
GSM5117 Isoflurane 5 exposures-1 39.0
GSM5118 Isoflurane 5 exposures-2 49.5
GSM5119 Isoflurane 5 exposures-3 42.6
GSM11379 Control 10 66.6
GSM11380 Control 11 62.7
GSM11381 Control 12 35.9

ID GSE8911
Title Skeletal muscle after fine needle stimulation
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM225891 Skeletal muscle sample from fine needle-stimulated hindlimb Strain: Lewis, Gender: Male, Body Weight: 275g, Tissue: Skeletal muscle sample from fine nnedle-stimulated hindlimb 249.969
GSM225892 Skeletal muscle sample from control hindlimb Strain: Lewis, Gender: Male, Body weight: 275g, Tissue: skeletal muscle sample from non fine needle-stimulated hindlimb 150.609