Gene symbol: Pink1

Organism: Rattus norvegicus

Summary: Enables protein serine/threonine kinase activity and ubiquitin protein ligase binding activity. Involved in several processes, including cellular response to hydrogen sulfide; negative regulation of cell death; and positive regulation of NMDA glutamate receptor activity. Located in endoplasmic reticulum; growth cone; and mitochondrial envelope. Used to study Parkinson's disease and Parkinsonism. Human ortholog(s) of this gene implicated in Parkinson's disease and Parkinson's disease 6. Orthologous to human PINK1 (PTEN induced kinase 1). [provided by Alliance of Genome Resources, Apr 2022]

NCBI gene ID: 298575 Ensembl:ENSRNOG00000015385 AllianceGenome:RGD:1305769


GO Annotation


Category Term ID Term description
Process GO:0000266 Mitochondrial fission
Process GO:0000422 Autophagy of mitochondrion
Process GO:0000423 Mitophagy
Process GO:0001666 Response to hypoxia
Process GO:0001932 Regulation of protein phosphorylation
Process GO:0001934 Positive regulation of protein phosphorylation
Process GO:0002082 Regulation of oxidative phosphorylation
Process GO:0002376 Immune system process
Process GO:0002520 Immune system development
Process GO:0002931 Response to ischemia
Process GO:0006091 Generation of precursor metabolites and energy
Process GO:0006355 Regulation of transcription, DNA-templated
Process GO:0006417 Regulation of translation
Process GO:0006468 Protein phosphorylation
Process GO:0006793 Phosphorus metabolic process
Process GO:0006796 Phosphate-containing compound metabolic process
Process GO:0006807 Nitrogen compound metabolic process
Process GO:0006810 Transport
Process GO:0006811 Ion transport
Process GO:0006812 Cation transport
Process GO:0006839 Mitochondrial transport
Process GO:0006914 Autophagy
Process GO:0006950 Response to stress
Process GO:0006979 Response to oxidative stress
Process GO:0006996 Organelle organization
Process GO:0007005 Mitochondrion organization
Process GO:0007034 Vacuolar transport
Process GO:0007041 Lysosomal transport
Process GO:0007154 Cell communication
Process GO:0007165 Signal transduction
Process GO:0007267 Cell-cell signaling
Process GO:0007275 Multicellular organism development
Process GO:0008104 Protein localization
Process GO:0008152 Metabolic process
Process GO:0009056 Catabolic process
Process GO:0009628 Response to abiotic stimulus
Process GO:0009636 Response to toxic substance
Process GO:0009889 Regulation of biosynthetic process
Process GO:0009891 Positive regulation of biosynthetic process
Process GO:0009892 Negative regulation of metabolic process
Process GO:0009893 Positive regulation of metabolic process
Process GO:0009894 Regulation of catabolic process
Process GO:0009895 Negative regulation of catabolic process
Process GO:0009896 Positive regulation of catabolic process
Process GO:0009966 Regulation of signal transduction
Process GO:0009967 Positive regulation of signal transduction
Process GO:0009968 Negative regulation of signal transduction
Process GO:0009987 Cellular process
Process GO:0010035 Response to inorganic substance
Process GO:0010310 Regulation of hydrogen peroxide metabolic process
Process GO:0010468 Regulation of gene expression
Process GO:0010469 Regulation of signaling receptor activity
Process GO:0010506 Regulation of autophagy
Process GO:0010507 Negative regulation of autophagy
Process GO:0010508 Positive regulation of autophagy
Process GO:0010556 Regulation of macromolecule biosynthetic process
Process GO:0010557 Positive regulation of macromolecule biosynthetic process
Process GO:0010562 Positive regulation of phosphorus metabolic process
Process GO:0010565 Regulation of cellular ketone metabolic process
Process GO:0010604 Positive regulation of macromolecule metabolic process
Process GO:0010605 Negative regulation of macromolecule metabolic process
Process GO:0010608 Post-transcriptional regulation of gene expression
Process GO:0010628 Positive regulation of gene expression
Process GO:0010629 Negative regulation of gene expression
Process GO:0010638 Positive regulation of organelle organization
Process GO:0010639 Negative regulation of organelle organization
Process GO:0010646 Regulation of cell communication
Process GO:0010647 Positive regulation of cell communication
Process GO:0010648 Negative regulation of cell communication
Process GO:0010821 Regulation of mitochondrion organization
Process GO:0010822 Positive regulation of mitochondrion organization
Process GO:0010823 Negative regulation of mitochondrion organization
Process GO:0010941 Regulation of cell death
Process GO:0014046 Dopamine secretion
Process GO:0014059 Regulation of dopamine secretion
Process GO:0015844 Monoamine transport
Process GO:0015850 Organic hydroxy compound transport
Process GO:0015872 Dopamine transport
Process GO:0015980 Energy derivation by oxidation of organic compounds
Process GO:0016043 Cellular component organization
Process GO:0016192 Vesicle-mediated transport
Process GO:0016236 Macroautophagy
Process GO:0016239 Positive regulation of macroautophagy
Process GO:0016241 Regulation of macroautophagy
Process GO:0016242 Negative regulation of macroautophagy
Process GO:0016310 Phosphorylation
Process GO:0016567 Protein ubiquitination
Process GO:0018105 Peptidyl-serine phosphorylation
Process GO:0018193 Peptidyl-amino acid modification
Process GO:0018209 Peptidyl-serine modification
Process GO:0019216 Regulation of lipid metabolic process
Process GO:0019217 Regulation of fatty acid metabolic process
Process GO:0019219 Regulation of nucleobase-containing compound metabolic process
Process GO:0019220 Regulation of phosphate metabolic process
Process GO:0019222 Regulation of metabolic process
Process GO:0019538 Protein metabolic process
Process GO:0022411 Cellular component disassembly
Process GO:0022603 Regulation of anatomical structure morphogenesis
Process GO:0022898 Regulation of transmembrane transporter activity
Process GO:0022900 Electron transport chain
Process GO:0022904 Respiratory electron transport chain
Process GO:0023051 Regulation of signaling
Process GO:0023052 Signaling
Process GO:0023056 Positive regulation of signaling
Process GO:0023057 Negative regulation of signaling
Process GO:0023061 Signal release
Process GO:0030097 Hemopoiesis
Process GO:0031056 Regulation of histone modification
Process GO:0031058 Positive regulation of histone modification
Process GO:0031063 Regulation of histone deacetylation
Process GO:0031065 Positive regulation of histone deacetylation
Process GO:0031323 Regulation of cellular metabolic process
Process GO:0031324 Negative regulation of cellular metabolic process
Process GO:0031325 Positive regulation of cellular metabolic process
Process GO:0031326 Regulation of cellular biosynthetic process
Process GO:0031328 Positive regulation of cellular biosynthetic process
Process GO:0031329 Regulation of cellular catabolic process
Process GO:0031330 Negative regulation of cellular catabolic process
Process GO:0031331 Positive regulation of cellular catabolic process
Process GO:0031396 Regulation of protein ubiquitination
Process GO:0031399 Regulation of protein modification process
Process GO:0031401 Positive regulation of protein modification process
Process GO:0031647 Regulation of protein stability
Process GO:0031998 Regulation of fatty acid beta-oxidation
Process GO:0031999 Negative regulation of fatty acid beta-oxidation
Process GO:0032225 Regulation of synaptic transmission, dopaminergic
Process GO:0032226 Positive regulation of synaptic transmission, dopaminergic
Process GO:0032386 Regulation of intracellular transport
Process GO:0032409 Regulation of transporter activity
Process GO:0032411 Positive regulation of transporter activity
Process GO:0032412 Regulation of ion transmembrane transporter activity
Process GO:0032414 Positive regulation of ion transmembrane transporter activity
Process GO:0032446 Protein modification by small protein conjugation
Process GO:0032501 Multicellular organismal process
Process GO:0032502 Developmental process
Process GO:0032507 Maintenance of protein location in cell
Process GO:0032879 Regulation of localization
Process GO:0032880 Regulation of protein localization
Process GO:0032940 Secretion by cell
Process GO:0033036 Macromolecule localization
Process GO:0033043 Regulation of organelle organization
Process GO:0033135 Regulation of peptidyl-serine phosphorylation
Process GO:0033138 Positive regulation of peptidyl-serine phosphorylation
Process GO:0033157 Regulation of intracellular protein transport
Process GO:0033365 Protein localization to organelle
Process GO:0033554 Cellular response to stress
Process GO:0033603 Positive regulation of dopamine secretion
Process GO:0033605 Positive regulation of catecholamine secretion
Process GO:0034248 Regulation of cellular amide metabolic process
Process GO:0034250 Positive regulation of cellular amide metabolic process
Process GO:0034599 Cellular response to oxidative stress
Process GO:0034762 Regulation of transmembrane transport
Process GO:0034764 Positive regulation of transmembrane transport
Process GO:0034765 Regulation of ion transmembrane transport
Process GO:0034767 Positive regulation of ion transmembrane transport
Process GO:0035303 Regulation of dephosphorylation
Process GO:0035304 Regulation of protein dephosphorylation
Process GO:0035306 Positive regulation of dephosphorylation
Process GO:0035307 Positive regulation of protein dephosphorylation
Process GO:0035556 Intracellular signal transduction
Process GO:0036211 Protein modification process
Process GO:0036289 Peptidyl-serine autophosphorylation
Process GO:0036293 Response to decreased oxygen levels
Process GO:0036294 Cellular response to decreased oxygen levels
Process GO:0042221 Response to chemical
Process GO:0042325 Regulation of phosphorylation
Process GO:0042327 Positive regulation of phosphorylation
Process GO:0042391 Regulation of membrane potential
Process GO:0042981 Regulation of apoptotic process
Process GO:0043066 Negative regulation of apoptotic process
Process GO:0043067 Regulation of programmed cell death
Process GO:0043069 Negative regulation of programmed cell death
Process GO:0043085 Positive regulation of catalytic activity
Process GO:0043122 Regulation of I-kappaB kinase/NF-kappaB signaling
Process GO:0043123 Positive regulation of I-kappaB kinase/NF-kappaB signaling
Process GO:0043170 Macromolecule metabolic process
Process GO:0043254 Regulation of protein-containing complex assembly
Process GO:0043269 Regulation of ion transport
Process GO:0043270 Positive regulation of ion transport
Process GO:0043412 Macromolecule modification
Process GO:0043457 Regulation of cellular respiration
Process GO:0043467 Regulation of generation of precursor metabolites and energy
Process GO:0043523 Regulation of neuron apoptotic process
Process GO:0043524 Negative regulation of neuron apoptotic process
Process GO:0044087 Regulation of cellular component biogenesis
Process GO:0044088 Regulation of vacuole organization
Process GO:0044093 Positive regulation of molecular function
Process GO:0044237 Cellular metabolic process
Process GO:0044238 Primary metabolic process
Process GO:0044248 Cellular catabolic process
Process GO:0045184 Establishment of protein localization
Process GO:0045185 Maintenance of protein location
Process GO:0045333 Cellular respiration
Process GO:0045727 Positive regulation of translation
Process GO:0045833 Negative regulation of lipid metabolic process
Process GO:0045922 Negative regulation of fatty acid metabolic process
Process GO:0045937 Positive regulation of phosphate metabolic process
Process GO:0046320 Regulation of fatty acid oxidation
Process GO:0046322 Negative regulation of fatty acid oxidation
Process GO:0046777 Protein autophosphorylation
Process GO:0046903 Secretion
Process GO:0046907 Intracellular transport
Process GO:0048285 Organelle fission
Process GO:0048513 Animal organ development
Process GO:0048518 Positive regulation of biological process
Process GO:0048519 Negative regulation of biological process
Process GO:0048522 Positive regulation of cellular process
Process GO:0048523 Negative regulation of cellular process
Process GO:0048534 Hematopoietic or lymphoid organ development
Process GO:0048583 Regulation of response to stimulus
Process GO:0048584 Positive regulation of response to stimulus
Process GO:0048585 Negative regulation of response to stimulus
Process GO:0048731 System development
Process GO:0048856 Anatomical structure development
Process GO:0050432 Catecholamine secretion
Process GO:0050433 Regulation of catecholamine secretion
Process GO:0050789 Regulation of biological process
Process GO:0050790 Regulation of catalytic activity
Process GO:0050793 Regulation of developmental process
Process GO:0050794 Regulation of cellular process
Process GO:0050804 Modulation of chemical synaptic transmission
Process GO:0050806 Positive regulation of synaptic transmission
Process GO:0050821 Protein stabilization
Process GO:0050896 Response to stimulus
Process GO:0050994 Regulation of lipid catabolic process
Process GO:0050995 Negative regulation of lipid catabolic process
Process GO:0051046 Regulation of secretion
Process GO:0051047 Positive regulation of secretion
Process GO:0051049 Regulation of transport
Process GO:0051050 Positive regulation of transport
Process GO:0051090 Regulation of DNA-binding transcription factor activity
Process GO:0051091 Positive regulation of DNA-binding transcription factor activity
Process GO:0051093 Negative regulation of developmental process
Process GO:0051094 Positive regulation of developmental process
Process GO:0051128 Regulation of cellular component organization
Process GO:0051129 Negative regulation of cellular component organization
Process GO:0051130 Positive regulation of cellular component organization
Process GO:0051171 Regulation of nitrogen compound metabolic process
Process GO:0051173 Positive regulation of nitrogen compound metabolic process
Process GO:0051174 Regulation of phosphorus metabolic process
Process GO:0051179 Localization
Process GO:0051223 Regulation of protein transport
Process GO:0051234 Establishment of localization
Process GO:0051235 Maintenance of location
Process GO:0051246 Regulation of protein metabolic process
Process GO:0051247 Positive regulation of protein metabolic process
Process GO:0051252 Regulation of RNA metabolic process
Process GO:0051336 Regulation of hydrolase activity
Process GO:0051345 Positive regulation of hydrolase activity
Process GO:0051641 Cellular localization
Process GO:0051649 Establishment of localization in cell
Process GO:0051651 Maintenance of location in cell
Process GO:0051716 Cellular response to stimulus
Process GO:0051881 Regulation of mitochondrial membrane potential
Process GO:0051937 Catecholamine transport
Process GO:0051952 Regulation of amine transport
Process GO:0051954 Positive regulation of amine transport
Process GO:0060255 Regulation of macromolecule metabolic process
Process GO:0060341 Regulation of cellular localization
Process GO:0060548 Negative regulation of cell death
Process GO:0061726 Mitochondrion disassembly
Process GO:0061912 Selective autophagy
Process GO:0061919 Process utilizing autophagic mechanism
Process GO:0062012 Regulation of small molecule metabolic process
Process GO:0062014 Negative regulation of small molecule metabolic process
Process GO:0062197 Cellular response to chemical stress
Process GO:0065007 Biological regulation
Process GO:0065008 Regulation of biological quality
Process GO:0065009 Regulation of molecular function
Process GO:0070201 Regulation of establishment of protein localization
Process GO:0070482 Response to oxygen levels
Process GO:0070585 Protein localization to mitochondrion
Process GO:0070647 Protein modification by small protein conjugation or removal
Process GO:0070727 Cellular macromolecule localization
Process GO:0070887 Cellular response to chemical stimulus
Process GO:0071453 Cellular response to oxygen levels
Process GO:0071456 Cellular response to hypoxia
Process GO:0071702 Organic substance transport
Process GO:0071704 Organic substance metabolic process
Process GO:0071705 Nitrogen compound transport
Process GO:0071840 Cellular component organization or biogenesis
Process GO:0072594 Establishment of protein localization to organelle
Process GO:0072595 Maintenance of protein localization in organelle
Process GO:0072655 Establishment of protein localization to mitochondrion
Process GO:0072656 Maintenance of protein location in mitochondrion
Process GO:0080090 Regulation of primary metabolic process
Process GO:0080134 Regulation of response to stress
Process GO:0080135 Regulation of cellular response to stress
Process GO:0090045 Positive regulation of deacetylase activity
Process GO:0090140 Regulation of mitochondrial fission
Process GO:0090141 Positive regulation of mitochondrial fission
Process GO:0090199 Regulation of release of cytochrome c from mitochondria
Process GO:0090200 Positive regulation of release of cytochrome c from mitochondria
Process GO:0090258 Negative regulation of mitochondrial fission
Process GO:0090311 Regulation of protein deacetylation
Process GO:0090312 Positive regulation of protein deacetylation
Process GO:0097237 Cellular response to toxic substance
Process GO:0098779 Positive regulation of mitophagy in response to mitochondrial depolarization
Process GO:0098780 Response to mitochondrial depolarisation
Process GO:0099074 Mitochondrion to lysosome transport
Process GO:0099075 Mitochondrion-derived vesicle mediated transport
Process GO:0099177 Regulation of trans-synaptic signaling
Process GO:0099601 Regulation of neurotransmitter receptor activity
Process GO:0140352 Export from cell
Process GO:0150065 Regulation of deacetylase activity
Process GO:1900037 Regulation of cellular response to hypoxia
Process GO:1900038 Negative regulation of cellular response to hypoxia
Process GO:1900407 Regulation of cellular response to oxidative stress
Process GO:1901031 Regulation of response to reactive oxygen species
Process GO:1901032 Negative regulation of response to reactive oxygen species
Process GO:1901214 Regulation of neuron death
Process GO:1901215 Negative regulation of neuron death
Process GO:1901298 Regulation of hydrogen peroxide-mediated programmed cell death
Process GO:1901299 Negative regulation of hydrogen peroxide-mediated programmed cell death
Process GO:1901524 Regulation of mitophagy
Process GO:1901525 Negative regulation of mitophagy
Process GO:1901564 Organonitrogen compound metabolic process
Process GO:1901725 Regulation of histone deacetylase activity
Process GO:1901727 Positive regulation of histone deacetylase activity
Process GO:1901857 Positive regulation of cellular respiration
Process GO:1902115 Regulation of organelle assembly
Process GO:1902116 Negative regulation of organelle assembly
Process GO:1902175 Regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
Process GO:1902176 Negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
Process GO:1902531 Regulation of intracellular signal transduction
Process GO:1902532 Negative regulation of intracellular signal transduction
Process GO:1902533 Positive regulation of intracellular signal transduction
Process GO:1902882 Regulation of response to oxidative stress
Process GO:1902883 Negative regulation of response to oxidative stress
Process GO:1902902 Negative regulation of autophagosome assembly
Process GO:1902956 Regulation of mitochondrial electron transport, NADH to ubiquinone
Process GO:1902958 Positive regulation of mitochondrial electron transport, NADH to ubiquinone
Process GO:1903008 Organelle disassembly
Process GO:1903146 Regulation of autophagy of mitochondrion
Process GO:1903147 Negative regulation of autophagy of mitochondrion
Process GO:1903201 Regulation of oxidative stress-induced cell death
Process GO:1903202 Negative regulation of oxidative stress-induced cell death
Process GO:1903203 Regulation of oxidative stress-induced neuron death
Process GO:1903204 Negative regulation of oxidative stress-induced neuron death
Process GO:1903205 Regulation of hydrogen peroxide-induced cell death
Process GO:1903206 Negative regulation of hydrogen peroxide-induced cell death
Process GO:1903207 Regulation of hydrogen peroxide-induced neuron death
Process GO:1903208 Negative regulation of hydrogen peroxide-induced neuron death
Process GO:1903214 Regulation of protein targeting to mitochondrion
Process GO:1903297 Regulation of hypoxia-induced intrinsic apoptotic signaling pathway
Process GO:1903298 Negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway
Process GO:1903320 Regulation of protein modification by small protein conjugation or removal
Process GO:1903376 Regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
Process GO:1903377 Negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
Process GO:1903383 Regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway
Process GO:1903384 Negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway
Process GO:1903506 Regulation of nucleic acid-templated transcription
Process GO:1903530 Regulation of secretion by cell
Process GO:1903532 Positive regulation of secretion by cell
Process GO:1903533 Regulation of protein targeting
Process GO:1903715 Regulation of aerobic respiration
Process GO:1903747 Regulation of establishment of protein localization to mitochondrion
Process GO:1903750 Regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide
Process GO:1903751 Negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide
Process GO:1903850 Regulation of cristae formation
Process GO:1903852 Positive regulation of cristae formation
Process GO:1904062 Regulation of cation transmembrane transport
Process GO:1904064 Positive regulation of cation transmembrane transport
Process GO:1904783 Positive regulation of NMDA glutamate receptor activity
Process GO:1904880 Response to hydrogen sulfide
Process GO:1904881 Cellular response to hydrogen sulfide
Process GO:1904923 Regulation of autophagy of mitochondrion in response to mitochondrial depolarization
Process GO:1904925 Positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization
Process GO:2000112 Regulation of cellular macromolecule biosynthetic process
Process GO:2000273 Positive regulation of signaling receptor activity
Process GO:2000310 Regulation of NMDA receptor activity
Process GO:2000377 Regulation of reactive oxygen species metabolic process
Process GO:2000378 Negative regulation of reactive oxygen species metabolic process
Process GO:2000785 Regulation of autophagosome assembly
Process GO:2001141 Regulation of RNA biosynthetic process
Process GO:2001233 Regulation of apoptotic signaling pathway
Process GO:2001234 Negative regulation of apoptotic signaling pathway
Process GO:2001242 Regulation of intrinsic apoptotic signaling pathway
Process GO:2001243 Negative regulation of intrinsic apoptotic signaling pathway
Process GO:2001257 Regulation of cation channel activity
Process GO:2001259 Positive regulation of cation channel activity
Component GO:0000785 Chromatin
Component GO:0005622 Intracellular anatomical structure
Component GO:0005634 Nucleus
Component GO:0005694 Chromosome
Component GO:0005737 Cytoplasm
Component GO:0005739 Mitochondrion
Component GO:0005740 Mitochondrial envelope
Component GO:0005741 Mitochondrial outer membrane
Component GO:0005743 Mitochondrial inner membrane
Component GO:0005758 Mitochondrial intermembrane space
Component GO:0005783 Endoplasmic reticulum
Component GO:0005829 Cytosol
Component GO:0005856 Cytoskeleton
Component GO:0012505 Endomembrane system
Component GO:0016020 Membrane
Component GO:0016021 Integral component of membrane
Component GO:0019866 Organelle inner membrane
Component GO:0019867 Outer membrane
Component GO:0030424 Axon
Component GO:0030426 Growth cone
Component GO:0030427 Site of polarized growth
Component GO:0031090 Organelle membrane
Component GO:0031224 Intrinsic component of membrane
Component GO:0031300 Intrinsic component of organelle membrane
Component GO:0031301 Integral component of organelle membrane
Component GO:0031306 Intrinsic component of mitochondrial outer membrane
Component GO:0031307 Integral component of mitochondrial outer membrane
Component GO:0031966 Mitochondrial membrane
Component GO:0031967 Organelle envelope
Component GO:0031968 Organelle outer membrane
Component GO:0031970 Organelle envelope lumen
Component GO:0031974 Membrane-enclosed lumen
Component GO:0031975 Envelope
Component GO:0032592 Integral component of mitochondrial membrane
Component GO:0042995 Cell projection
Component GO:0043005 Neuron projection
Component GO:0043226 Organelle
Component GO:0043227 Membrane-bounded organelle
Component GO:0043228 Non-membrane-bounded organelle
Component GO:0043229 Intracellular organelle
Component GO:0043231 Intracellular membrane-bounded organelle
Component GO:0043232 Intracellular non-membrane-bounded organelle
Component GO:0043233 Organelle lumen
Component GO:0044297 Cell body
Component GO:0048471 Perinuclear region of cytoplasm
Component GO:0070013 Intracellular organelle lumen
Component GO:0097386 Glial cell projection
Component GO:0097449 Astrocyte projection
Component GO:0098573 Intrinsic component of mitochondrial membrane
Component GO:0098588 Bounding membrane of organelle
Component GO:0110165 Cellular anatomical entity
Component GO:0120025 Plasma membrane bounded cell projection
Component GO:0150034 Distal axon
Function GO:0000166 Nucleotide binding
Function GO:0000287 Magnesium ion binding
Function GO:0002020 Protease binding
Function GO:0003824 Catalytic activity
Function GO:0004672 Protein kinase activity
Function GO:0004674 Protein serine/threonine kinase activity
Function GO:0005488 Binding
Function GO:0005515 Protein binding
Function GO:0005524 ATP binding
Function GO:0010857 Calcium-dependent protein kinase activity
Function GO:0016301 Kinase activity
Function GO:0016740 Transferase activity
Function GO:0016772 Transferase activity, transferring phosphorus-containing groups
Function GO:0016773 Phosphotransferase activity, alcohol group as acceptor
Function GO:0017076 Purine nucleotide binding
Function GO:0019899 Enzyme binding
Function GO:0019900 Kinase binding
Function GO:0019901 Protein kinase binding
Function GO:0019904 Protein domain specific binding
Function GO:0030554 Adenyl nucleotide binding
Function GO:0031625 Ubiquitin protein ligase binding
Function GO:0032553 Ribonucleotide binding
Function GO:0032555 Purine ribonucleotide binding
Function GO:0032559 Adenyl ribonucleotide binding
Function GO:0035639 Purine ribonucleoside triphosphate binding
Function GO:0036094 Small molecule binding
Function GO:0043167 Ion binding
Function GO:0043168 Anion binding
Function GO:0043169 Cation binding
Function GO:0043422 Protein kinase B binding
Function GO:0044389 Ubiquitin-like protein ligase binding
Function GO:0044877 Protein-containing complex binding
Function GO:0046872 Metal ion binding
Function GO:0055131 C3HC4-type RING finger domain binding
Function GO:0097159 Organic cyclic compound binding
Function GO:0097367 Carbohydrate derivative binding
Function GO:0106310 Protein serine kinase activity
Function GO:0140096 Catalytic activity, acting on a protein
Function GO:1901265 Nucleoside phosphate binding
Function GO:1901363 Heterocyclic compound binding
Function GO:1904841 TORC2 complex binding

Pathway annotation


Category Term ID Term description
RCTM RNO-1632852 Macroautophagy
RCTM RNO-5205647 Mitophagy
RCTM RNO-5205685 PINK1-PRKN Mediated Mitophagy
RCTM RNO-9612973 Autophagy
RCTM RNO-9663891 Selective autophagy

Expression profile of Pink1 in omics data



ID GSE100499
Title Exploring acupuncture mechanism in preconditioning of IRI
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM2685201 MX1 tissue: Myocardium gender: male 15.7693935
GSM2685202 MX2 tissue: Myocardium gender: female 15.8994805
GSM2685203 MX3 tissue: Myocardium gender: female 16.33072
GSM2685204 MX4 tissue: Myocardium gender: male 15.8253675
GSM2685205 DZ1 tissue: Myocardium gender: male 15.8089205
GSM2685206 DZ2 tissue: Myocardium gender: male 15.915149500000002
GSM2685207 DZ3 tissue: Myocardium gender: female 16.095166
GSM2685208 DZ4 tissue: Myocardium gender: female 15.920184500000001
GSM2685209 JJ1 tissue: Myocardium gender: male 15.69106575
GSM2685210 JJ2 tissue: Myocardium gender: female 15.79900925
GSM2685211 JJ3 tissue: Myocardium gender: female 16.0796705
GSM2685212 JJ4 tissue: Myocardium gender: male 15.6416885
GSM2685213 NG1 tissue: Myocardium gender: male 15.76915825
GSM2685214 NG2 tissue: Myocardium gender: female 15.785387499999999
GSM2685215 NG3 tissue: Myocardium gender: male 15.9258445
GSM2685216 NG4 tissue: Myocardium gender: female 15.8514695
GSM2685217 YL1 tissue: Myocardium gender: male 15.787873
GSM2685218 YL2 tissue: Myocardium gender: male 15.6978995
GSM2685219 YL3 tissue: Myocardium gender: female 16.201110999999997
GSM2685220 YL4 tissue: Myocardium gender: female 16.133582
GSM2685221 QC1 tissue: Myocardium gender: male 15.5919705
GSM2685222 QC2 tissue: Myocardium gender: male 15.6538395
GSM2685223 QC3 tissue: Myocardium gender: female 16.072669
GSM2685224 QC4 tissue: Myocardium gender: female 16.189703

ID GSE136833
Title Effects of lidocaine on the expression of rat spinal cord
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM4058984 Control_1 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 7.789570556
GSM4058985 Control_2 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 7.694983276
GSM4058986 Control_3 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 7.710884434
GSM4058987 Lidocaine_1 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 7.820099006
GSM4058988 Lidocaine_2 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 7.810103467
GSM4058989 Lidocaine_3 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 7.308921761

ID GSE138454
Title Impact of inflammation on hepatic subcellular energetics in anesthetized rats
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM4108997 Sample 1 Isoflurane sepsis anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 447.0
GSM4108998 Sample 2 Isoflurane sepsis anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 356.0
GSM4108999 Sample 3 Isoflurane sepsis anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 421.0
GSM4109000 Sample 4 Isoflurane sepsis anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 289.0
GSM4109001 Sample 5 Isoflurane control anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 582.0
GSM4109002 Sample 6 Isoflurane control anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 638.0
GSM4109003 Sample 7 Isoflurane control anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 785.0
GSM4109004 Sample 8 Isoflurane control anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 1446.0
GSM4109005 Sample9 Propofol sepsis anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 356.0
GSM4109006 Sample10 Propofol sepsis anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 434.0
GSM4109007 Sample11 Propofol sepsis anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 361.0
GSM4109008 Sample12 Propofol sepsis anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 663.0
GSM4109009 Sample13 Propofol control anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 295.0
GSM4109010 Sample14 Propofol control anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 408.0
GSM4109011 Sample 15 Propofol control anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 524.0
GSM4109012 Sample16 Propofol control anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 483.0

ID GSE139220
Title Expression data from sevoflurane anesthesia treated rat
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM4134285 Brain_Control_rep1 strain: Sprague-Dawley age: 18-month old treatment: control tissue: hippocampus 9.043847
GSM4134286 Brain_Control_rep2 strain: Sprague-Dawley age: 18-month old treatment: control tissue: hippocampus 9.210818
GSM4134287 Brain_Control_rep3 strain: Sprague-Dawley age: 18-month old treatment: control tissue: hippocampus 9.173994
GSM4134288 Brain_Sevoflurane_rep1 strain: Sprague-Dawley age: 18-month old treatment: sevoflurane anesthesia tissue: hippocampus 9.277544
GSM4134289 Brain_Sevoflurane_rep2 strain: Sprague-Dawley age: 18-month old treatment: sevoflurane anesthesia tissue: hippocampus 9.213962
GSM4134290 Brain_Sevoflurane_rep3 strain: Sprague-Dawley age: 18-month old treatment: sevoflurane anesthesia tissue: hippocampus 9.252635

ID GSE143895
Title GPR160 de-orphanization reveals critical roles in neuropathic pain in rodents
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM4276356 dhsc01 strain: Sprague Dawley tissue: DHSC treatment: CCI 206.686
GSM4276357 dhsc03 strain: Sprague Dawley tissue: DHSC treatment: CCI 189.69
GSM4276358 dhsc05 strain: Sprague Dawley tissue: DHSC treatment: CCI 185.93
GSM4276359 dhsc13 strain: Sprague Dawley tissue: DHSC treatment: SHAM 224.072
GSM4276360 dhsc15 strain: Sprague Dawley tissue: DHSC treatment: SHAM 218.834

ID GSE157924
Title Regulation of acupuncture on genes in brain stem
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM4780973 Rattus_JSSZ(Sham) tissue: Rattus brainstem of modeling treatment: Sham 10.70162662
GSM4780974 Rattus_JXZ(Hand Acu) tissue: Rattus brainstem of modeling treatment: Hand Acu 10.57925632
GSM4780975 Rattus_MXZ(TBI) tissue: Rattus brainstem of modeling treatment: TBI 10.71592542

ID GSE1779
Title Effect of Isoflurane and LTM on basolateral amygdala
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM30790 baseline control 01 male, 275-300g 1728.6
GSM30791 baseline control 02 male, 275-300g 1929.7
GSM30792 baseline control 03 male, 275-300g 2156.7
GSM30793 baseline control 04 male, 275-300g 1703.6
GSM30794 baseline control 05 male, 275-300g 2269.5
GSM30795 baseline control 06 male, 275-300g 1936.5
GSM30796 baseline control 07 male, 275-300g 2107.2
GSM30797 baseline control 08 male, 275-300g 2445.7
GSM30798 baseline control 09 male, 275-300g 2064.3
GSM30799 pain 01 2131.3
GSM30800 pain 02 1918.9
GSM30801 pain 03 1673.1
GSM30802 pain 04 2025.2
GSM30803 pain 05 1714.8
GSM30804 FC 01 1968.1
GSM30805 FC 02 2127.1
GSM30806 FC 03 1836.3
GSM30807 FC 04 1850.9
GSM30808 FC 05 1831.2
GSM30809 IFC 01 1914.5
GSM30810 IFC 02 2014.4
GSM30811 IFC 03 2126.2
GSM30812 IFC 04 1765.5
GSM30813 IFC 05 1744.4
GSM99800 isoflurane 01 male, 275-300g 1768.1
GSM99801 isoflurane 02 male, 275-300g 1374.4
GSM99802 isoflurane 03 male, 275-300g 1788.2
GSM99803 isoflurane 04 male, 275-300g 1606.7
GSM99804 isoflurane 05 male, 275-300g 2047.6

ID GSE190472
Title Study on VEGF regulation mechanism of acupuncture improving endometrial receptivity in IVF-ET
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM5724271 model 21 Sex: female tissue: Uterine tissue condition: model 109.226
GSM5724272 model 22 Sex: female tissue: Uterine tissue condition: model 110.9617
GSM5724273 model 23 Sex: female tissue: Uterine tissue condition: model 109.3597
GSM5724274 treatment31 Sex: female tissue: Uterine tissue condition: treatment 78.3659
GSM5724275 treatment32 Sex: female tissue: Uterine tissue condition: treatment 74.961
GSM5724276 treatment33 Sex: female tissue: Uterine tissue condition: treatment 117.8783
GSM5724277 control 41 Sex: female tissue: Uterine tissue condition: control 77.3051
GSM5724278 control 42 Sex: female tissue: Uterine tissue condition: control 75.1714
GSM5724279 control 43 Sex: female tissue: Uterine tissue condition: control 97.7222

ID GSE192399
Title Gene expression of brain regions activated by sevoflurane and propofol
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM5746332 LHb, Sevoflurane, 60mins brain region: the lateral habenula (LHb) treatment: Sevoflurane 9.50563
GSM5746333 LHb, O2, 60mins brain region: the lateral habenula (LHb) treatment: O2 9.46796
GSM5746334 MHb, Sevoflurane, 60mins brain region: the medial habenula (MHb) treatment: Sevoflurane 8.22735
GSM5746335 MHb, O2, 60mins brain region: the medial habenula (MHb) treatment: O2 8.18276
GSM5746336 Sol, Sevoflurane, 60mins brain region: the solitary nucleus (Sol) treatment: Sevoflurane 10.4904
GSM5746337 Sol, O2, 60mins brain region: the solitary nucleus (Sol) treatment: O2 10.3005
GSM5746338 Mve, Sevoflurane, 60mins brain region: the medial vestibular nucleus (MVe) treatment: Sevoflurane 11.1514
GSM5746339 Mve, O2, 60mins brain region: the medial vestibular nucleus (MVe) treatment: O2 11.0341
GSM5746340 LHb, Propofol, 60mins brain region: the lateral habenula (LHb) treatment: Propofol 9.49382
GSM5746341 LHb, Intralipos, 60mins brain region: the lateral habenula (LHb) treatment: Intralipos 10.1214
GSM5746342 MHb, Propofol, 60mins brain region: the medial habenula (MHb) treatment: Propofol 8.88196
GSM5746343 MHb, Intralipos, 60mins brain region: the medial habenula (MHb) treatment: Intralipos 8.62804
GSM5746344 Sol, Propofol, 60mins brain region: the solitary nucleus (Sol) treatment: Propofol 10.1391
GSM5746345 Sol, Intralipos, 60mins brain region: the solitary nucleus (Sol) treatment: Intralipos 9.49826
GSM5746346 MVe, Propofol, 60mins brain region: the medial vestibular nucleus (MVe) treatment: Propofol 10.9337
GSM5746347 MVe, Intralipos, 60mins brain region: the medial vestibular nucleus (MVe) treatment: Intralipos 10.7967

ID GSE232804
Title EGR3 regulates opioid-related nociception and motivation in male rats
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM7383519 ww01_Saline_Saline tissue: Brain / mPFC pain: Saline drug: Salin 554.0
GSM7383520 ww02_Saline_Saline tissue: Brain / mPFC pain: Saline drug: Saline 601.0
GSM7383521 ww03_Saline_Saline tissue: Brain / mPFC pain: Saline drug: Salin 536.0
GSM7383522 ww05_Saline_Saline tissue: Brain / mPFC pain: Saline drug: Saline 574.0
GSM7383523 ww06_Saline_Saline tissue: Brain / mPFC pain: Saline drug: Salin 607.0
GSM7383524 ww07_Saline_Saline tissue: Brain / mPFC pain: Saline drug: Saline 592.0
GSM7383525 ww08_Saline_Saline tissue: Brain / mPFC pain: Saline drug: Salin 530.0
GSM7383526 ww10_Saline_Saline tissue: Brain / mPFC pain: Saline drug: Saline 560.0
GSM7383527 ww12_Saline_OXY tissue: Brain / mPFC pain: Saline drug: OXY 486.0
GSM7383528 ww13_Saline_OXY tissue: Brain / mPFC pain: Saline drug: OXY 727.0
GSM7383529 ww14_Saline_OXY tissue: Brain / mPFC pain: Saline drug: OXY 566.0
GSM7383530 ww15_Saline_OXY tissue: Brain / mPFC pain: Saline drug: OXY 669.0
GSM7383531 ww16_Saline_OXY tissue: Brain / mPFC pain: Saline drug: OXY 583.0
GSM7383532 ww17_Saline_OXY tissue: Brain / mPFC pain: Saline drug: OXY 722.0
GSM7383533 ww18_Saline_OXY tissue: Brain / mPFC pain: Saline drug: OXY 745.0
GSM7383534 ww20_Saline_OXY tissue: Brain / mPFC pain: Saline drug: OXY 415.0
GSM7383535 ww21_CFA_Saline tissue: Brain / mPFC pain: CFA drug: Saline 657.0
GSM7383536 ww22_CFA_Saline tissue: Brain / mPFC pain: CFA drug: Saline 573.0
GSM7383537 ww23_CFA_Saline tissue: Brain / mPFC pain: CFA drug: Saline 494.0
GSM7383538 ww24_CFA_Saline tissue: Brain / mPFC pain: CFA drug: Saline 531.0
GSM7383539 ww26_CFA_Saline tissue: Brain / mPFC pain: CFA drug: Saline 572.0
GSM7383540 ww27_CFA_Saline tissue: Brain / mPFC pain: CFA drug: Saline 892.0
GSM7383541 ww28_CFA_Saline tissue: Brain / mPFC pain: CFA drug: Saline 841.0
GSM7383542 ww30_CFA_Saline tissue: Brain / mPFC pain: CFA drug: Saline 689.0
GSM7383543 ww31_CFA_OXY tissue: Brain / mPFC pain: CFA drug: OXY 580.0
GSM7383544 ww32_CFA_OXY tissue: Brain / mPFC pain: CFA drug: OXY 458.0
GSM7383545 ww34_CFA_OXY tissue: Brain / mPFC pain: CFA drug: OXY 654.0
GSM7383546 ww35_CFA_OXY tissue: Brain / mPFC pain: CFA drug: OXY 719.0
GSM7383547 ww36_CFA_OXY tissue: Brain / mPFC pain: CFA drug: OXY 744.0
GSM7383548 ww37_CFA_OXY tissue: Brain / mPFC pain: CFA drug: OXY 764.0
GSM7383549 ww38_CFA_OXY tissue: Brain / mPFC pain: CFA drug: OXY 637.0
GSM7383550 www09_Saline_Saline tissue: Brain / mPFC pain: Saline drug: Saline 796.0
GSM7383551 www19_Saline_OXY tissue: Brain / mPFC pain: Saline drug: OXY 767.0
GSM7383552 www29_CFA_Saline tissue: Brain / mPFC pain: CFA drug: Saline 666.0
GSM7383553 www33_CFA_OXY tissue: Brain / mPFC pain: CFA drug: OXY 688.0
GSM7383554 www39_CFA_OXY tissue: Brain / mPFC pain: CFA drug: OXY 457.0

ID GSE244436
Title Similarity and dissimilarity in alteration of gene expression profile associated with inhalational anesthesia between sevoflurane and desflurane
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM7816143 Liver, Control for SevoAnes tissue: liver genotype: wild type treatment: Control for SevoAnes 122.531212
GSM7816144 Liver, Anesthetized with sevoflurane for 6 h tissue: liver genotype: wild type treatment: Anesthetized with sevoflurane for 6 h 102.906197
GSM7816145 Liver, Control for DesAnes tissue: liver genotype: wild type treatment: Control for DesAnes 88.112831
GSM7816146 Liver, Anesthetized with desflurane for 6 h tissue: liver genotype: wild type treatment: Anesthetized with desflurane for 6 h 133.975723

ID GSE2982
Title Effect of inhaled anesthetic to cultured cortical neurons
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM61779 Cell Culture Exposure (control1) Cy3 label;Cy5; 0.0196
GSM61796 Cell Culture Exposure (control2) Cy3; Cy5 -0.127
GSM61797 Cell Culture Exposure (control3) Cy3; Cy5 -0.0172
GSM61798 Cell Culture Exposure (1MAC Halo1) Cy3; Cy5 -0.21
GSM61799 Cell Culture Exposure (1MAC Halo2) Cy3; Cy5 -0.057
GSM61800 Cell Culture Exposure (1MAC Halo3) Cy3; Cy5 0.015
GSM61801 Cell Culture Exposure (3MAC Halo1) Cy3; Cy5 -0.233
GSM61802 Cell Culture Exposure (3MAC Halo2) Cy3; Cy5 -0.211
GSM61803 Cell Culture Exposure (3MAC Halo3) Cy3; Cy5 -0.226
GSM61804 Cell Culture Exposure (3MAC ISO1) Cy3; Cy5 0.00355
GSM61805 Cell Culture Exposure (3MAC ISO2) Cy3; Cy5 -0.0978
GSM61806 Cell Culture Exposure (3MAC ISO3) Cy3; Cy5 -0.0325

ID GSE48025
Title Affymetrix Chip Data of the Transcriptome of the Rheumatoid Arthritis Rat Model Treated with Acupuncture (Affymetrix, mRNA, batch1)
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM1165929 RAT_NORA_T0_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats before therapy 9.366207397
GSM1165930 RAT_NORA_T0_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats before therapy 9.730934681
GSM1165931 RAT_RA_T0_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats before therapy 9.68521679
GSM1165932 RAT_RA_T0_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats before therapy 9.09648575
GSM1165933 RAT_NORA_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 1 hour after therapy 9.278695747
GSM1165934 RAT_NORA_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 1 hour after therapy 10.2975547
GSM1165935 RAT_AP_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour acupuncture therapy 11.16358058
GSM1165936 RAT_AP_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour acupuncture therapy 9.422181051
GSM1165937 RAT_MTX_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour MTX therapy 9.789616504
GSM1165938 RAT_MTX_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour MTX therapy 9.259617769
GSM1165939 RAT_ANE_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour ANE therapy 10.76146789
GSM1165940 RAT_ANE_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour ANE therapy 9.888815352
GSM1165941 RAT_PLA_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour placebo therapy 9.724644335
GSM1165942 RAT_PLA_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour placebo therapy 10.74208364
GSM1165943 RAT_NORA_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 34 days after therapy 9.791677197
GSM1165944 RAT_NORA_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 34 days after therapy 10.11333907
GSM1165945 RAT_AP_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days acupuncture therapy 11.56851924
GSM1165946 RAT_AP_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days acupuncture therapy 10.42461999
GSM1165947 RAT_MTX_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days MTX therapy 10.44261573
GSM1165948 RAT_MTX_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days MTX therapy 9.62701789
GSM1165949 RAT_ANE_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days ANE therapy 10.18067569
GSM1165950 RAT_ANE_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days ANE therapy 9.507096108
GSM1165951 RAT_PLA_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days placebo therapy 9.48748907
GSM1165952 RAT_PLA_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days placebo therapy 9.448684446

ID GSE53897
Title Genome-wide analysis of dorsal root ganglion (DRG) gene expression after morphine or oxycodone treatment
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM1303240 DRG RVM1 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 8.224142
GSM1303241 DRG RVM2 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 8.228255
GSM1303242 DRG RVM3 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 8.052994
GSM1303243 DRG RVM7 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 8.353187
GSM1303244 DRG RVOx2 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 8.50119
GSM1303245 DRG RVOx3 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 8.044691
GSM1303246 DRG RVOx5 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 8.263607
GSM1303247 DRG RVOx7 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 8.141349
GSM1303248 DRG RVS4 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 8.046633
GSM1303249 DRG RVS5 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 8.386512
GSM1303250 DRG RVS6 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 8.393488
GSM1303251 DRG RVS7 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 8.20405
GSM1303252 DRG RSM1 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 8.463569
GSM1303253 DRG RSM2 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 8.112111
GSM1303254 DRG RSM4 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 8.295771
GSM1303255 DRG RSM5 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 8.22951
GSM1303256 DRG RSOx1 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 8.54456
GSM1303257 DRG RSOx2 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 8.231985
GSM1303258 DRG RSOx3 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 8.088827
GSM1303259 DRG RSOx4 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 8.035515
GSM1303260 DRG RSS1 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 8.346463
GSM1303261 DRG RSS2 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 8.090805
GSM1303262 DRG RSS3 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 8.273424
GSM1303263 DRG RSS6 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 8.222492

ID GSE55573
Title Using DNA microarray to screen intracellular signal pathways of hypoglycemic activity by electroacupuncture of Zusanli (ST36) acupoints in streptozotocin-induced rats with diabetes
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM1339443 Mock skeletal muscle strain: Wistar age: 8-10 week-old gender: Male 3091.448
GSM1339444 EA (electroacupuncture) skeletal muscle strain: Wistar age: 8-10 week-old gender: Male 2179.977

ID GSE58456
Title Affymetrix Chip Data of the Transcriptome of the Rheumatoid Arthritis Rat Model Treated with Acupuncture (Affymetrix, mRNA, batch 2)
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM1693996 Peripheral blood mononuclear cells from NORA before therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats before therapy 1546.08301
GSM1693997 Peripheral blood mononuclear cells from NORA before therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats before therapy 2731.573036
GSM1693998 Peripheral blood mononuclear cells from NORA before therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats before therapy 5879.259355
GSM1693999 Peripheral blood mononuclear cells from RA before therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats before therapy 1054.344753
GSM1694000 Peripheral blood mononuclear cells from RA before therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats before therapy 1722.222819
GSM1694001 Peripheral blood mononuclear cells from HAP after 34 days acupuncture therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats after 34 days acupuncture therapy 1944.800116
GSM1694002 Peripheral blood mononuclear cells from HAP after 34 days acupuncture therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats after 34 days acupuncture therapy 1907.329398
GSM1694003 Peripheral blood mononuclear cells from HAP after 34 days acupuncture therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats after 34 days acupuncture therapy 1942.725403
GSM1694004 Peripheral blood mononuclear cells from AP after 34 days acupuncture therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days acupuncture therapy 1773.912044
GSM1694005 Peripheral blood mononuclear cells from AP after 34 days acupuncture therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days acupuncture therapy 2627.154265
GSM1694006 Peripheral blood mononuclear cells from AP after 34 days acupuncture therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days acupuncture therapy 2390.975743
GSM1694007 Peripheral blood mononuclear cells from MTXAP after 34 days MTX&acupuncture therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days methotrexate & acupuncture therapy 2803.825697
GSM1694008 Peripheral blood mononuclear cells from MTXAP after 34 days MTX&acupuncture therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days methotrexate & acupuncture therapy 2923.796358
GSM1694009 Peripheral blood mononuclear cells from MTXAP after 34 days MTX&acupuncture therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days methotrexate & acupuncture therapy 825.6259567

ID GSE58460
Title Rheumatoid Arthritis Rat Model Treated with Acupuncture
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM1165929 RAT_NORA_T0_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats before therapy 9.366207397
GSM1165930 RAT_NORA_T0_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats before therapy 9.730934681
GSM1165931 RAT_RA_T0_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats before therapy 9.68521679
GSM1165932 RAT_RA_T0_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats before therapy 9.09648575
GSM1165933 RAT_NORA_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 1 hour after therapy 9.278695747
GSM1165934 RAT_NORA_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 1 hour after therapy 10.2975547
GSM1165935 RAT_AP_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour acupuncture therapy 11.16358058
GSM1165936 RAT_AP_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour acupuncture therapy 9.422181051
GSM1165937 RAT_MTX_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour MTX therapy 9.789616504
GSM1165938 RAT_MTX_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour MTX therapy 9.259617769
GSM1165939 RAT_ANE_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour ANE therapy 10.76146789
GSM1165940 RAT_ANE_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour ANE therapy 9.888815352
GSM1165941 RAT_PLA_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour placebo therapy 9.724644335
GSM1165942 RAT_PLA_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour placebo therapy 10.74208364
GSM1165943 RAT_NORA_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 34 days after therapy 9.791677197
GSM1165944 RAT_NORA_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 34 days after therapy 10.11333907
GSM1165945 RAT_AP_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days acupuncture therapy 11.56851924
GSM1165946 RAT_AP_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days acupuncture therapy 10.42461999
GSM1165947 RAT_MTX_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days MTX therapy 10.44261573
GSM1165948 RAT_MTX_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days MTX therapy 9.62701789
GSM1165949 RAT_ANE_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days ANE therapy 10.18067569
GSM1165950 RAT_ANE_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days ANE therapy 9.507096108
GSM1165951 RAT_PLA_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days placebo therapy 9.48748907
GSM1165952 RAT_PLA_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days placebo therapy 9.448684446
GSM1412003 RAT_NORA_T0_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412004 RAT_NORA_T0_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412005 RAT_RA_T0_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412006 RAT_RA_T0_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412007 RAT_NORA_1h_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412008 RAT_NORA_1h_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412009 RAT_AP_1h_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412010 RAT_AP_1h_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412011 RAT_MTX_1h_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412012 RAT_MTX_1h_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412013 RAT_ANE_1h_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412014 RAT_ANE_1h_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412015 RAT_PLA_1h_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412016 RAT_PLA_1h_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412017 RAT_NORA_34d_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412018 RAT_NORA_34d_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412019 RAT_AP_34d_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412020 RAT_AP_34d_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412021 RAT_MTX_34d_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412022 RAT_MTX_34d_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412023 RAT_ANE_34d_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412024 RAT_ANE_34d_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412025 RAT_PLA_34d_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412026 RAT_PLA_34d_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412027 RAT_RA_T0_1 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412028 RAT_RA_T0_2 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412029 RAT_AP_1h_1 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412030 RAT_AP_1h_2 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412031 RAT_PLA_1h_1 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412032 RAT_PLA_1h_2 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412033 RAT_AP_34d_1 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412034 RAT_AP_34d_2 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412035 RAT_PLA_34d_1 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412036 RAT_PLA_34d_2 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1693996 Peripheral blood mononuclear cells from NORA before therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats before therap 1546.08301
GSM1693997 Peripheral blood mononuclear cells from NORA before therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats before therapy 2731.573036
GSM1693998 Peripheral blood mononuclear cells from NORA before therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats before therapy 5879.259355
GSM1693999 Peripheral blood mononuclear cells from RA before therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats before therapy 1054.344753
GSM1694000 Peripheral blood mononuclear cells from RA before therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats before therapy 1722.222819
GSM1694001 Peripheral blood mononuclear cells from HAP after 34 days acupuncture therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats after 34 days acupuncture therapy 1944.800116
GSM1694002 Peripheral blood mononuclear cells from HAP after 34 days acupuncture therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats after 34 days acupuncture therap 1907.329398
GSM1694003 Peripheral blood mononuclear cells from HAP after 34 days acupuncture therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats after 34 days acupuncture therapy 1942.725403
GSM1694004 Peripheral blood mononuclear cells from AP after 34 days acupuncture therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days acupuncture therapy 1773.912044
GSM1694005 Peripheral blood mononuclear cells from AP after 34 days acupuncture therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days acupuncture therapy 2627.154265
GSM1694006 Peripheral blood mononuclear cells from AP after 34 days acupuncture therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days acupuncture therapy 2390.975743
GSM1694007 Peripheral blood mononuclear cells from MTXAP after 34 days MTX&acupuncture therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days methotrexate & acupuncture therapy 2803.825697
GSM1694008 Peripheral blood mononuclear cells from MTXAP after 34 days MTX&acupuncture therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days methotrexate & acupuncture therapy 2923.796358
GSM1694009 Peripheral blood mononuclear cells from MTXAP after 34 days MTX&acupuncture therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days methotrexate & acupuncture therapy 825.6259567

ID GSE8911
Title Skeletal muscle after fine needle stimulation
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM225891 Skeletal muscle sample from fine needle-stimulated hindlimb Strain: Lewis, Gender: Male, Body Weight: 275g, Tissue: Skeletal muscle sample from fine nnedle-stimulated hindlimb 1486.06
GSM225892 Skeletal muscle sample from control hindlimb Strain: Lewis, Gender: Male, Body weight: 275g, Tissue: skeletal muscle sample from non fine needle-stimulated hindlimb 1562.46