Gene symbol: Clec4e

Also known as: Mincle; Clecsf9

Organism: Rattus norvegicus

Summary: Predicted to enable several functions, including calcium ion binding activity; glycolipid binding activity; and pattern recognition receptor activity. Predicted to be involved in antifungal innate immune response; pattern recognition receptor signaling pathway; and positive regulation of cytokine production. Predicted to act upstream of or within Fc-gamma receptor signaling pathway; T cell differentiation involved in immune response; and defense response to bacterium. Predicted to be located in membrane. Predicted to be active in external side of plasma membrane and phagocytic vesicle membrane. Orthologous to human CLEC4E (C-type lectin domain family 4 member E). [provided by Alliance of Genome Resources, Apr 2022]

NCBI gene ID: 450223 Ensembl:ENSRNOG00000061394 AllianceGenome:RGD:1359298


GO Annotation


Category Term ID Term description
Process GO:0001775 Cell activation
Process GO:0001817 Regulation of cytokine production
Process GO:0001819 Positive regulation of cytokine production
Process GO:0002221 Pattern recognition receptor signaling pathway
Process GO:0002252 Immune effector process
Process GO:0002263 Cell activation involved in immune response
Process GO:0002285 Lymphocyte activation involved in immune response
Process GO:0002286 T cell activation involved in immune response
Process GO:0002292 T cell differentiation involved in immune response
Process GO:0002366 Leukocyte activation involved in immune response
Process GO:0002376 Immune system process
Process GO:0002520 Immune system development
Process GO:0002521 Leukocyte differentiation
Process GO:0002682 Regulation of immune system process
Process GO:0002764 Immune response-regulating signaling pathway
Process GO:0002768 Immune response-regulating cell surface receptor signaling pathway
Process GO:0006950 Response to stress
Process GO:0006952 Defense response
Process GO:0006955 Immune response
Process GO:0007154 Cell communication
Process GO:0007165 Signal transduction
Process GO:0007166 Cell surface receptor signaling pathway
Process GO:0007275 Multicellular organism development
Process GO:0009605 Response to external stimulus
Process GO:0009607 Response to biotic stimulus
Process GO:0009617 Response to bacterium
Process GO:0009620 Response to fungus
Process GO:0009893 Positive regulation of metabolic process
Process GO:0009987 Cellular process
Process GO:0010468 Regulation of gene expression
Process GO:0010604 Positive regulation of macromolecule metabolic process
Process GO:0010628 Positive regulation of gene expression
Process GO:0019222 Regulation of metabolic process
Process GO:0023052 Signaling
Process GO:0030097 Hemopoiesis
Process GO:0030098 Lymphocyte differentiation
Process GO:0030154 Cell differentiation
Process GO:0030217 T cell differentiation
Process GO:0032501 Multicellular organismal process
Process GO:0032502 Developmental process
Process GO:0038093 Fc receptor signaling pathway
Process GO:0038094 Fc-gamma receptor signaling pathway
Process GO:0042110 T cell activation
Process GO:0042742 Defense response to bacterium
Process GO:0043207 Response to external biotic stimulus
Process GO:0044419 Biological process involved in interspecies interaction between organisms
Process GO:0045087 Innate immune response
Process GO:0045321 Leukocyte activation
Process GO:0046649 Lymphocyte activation
Process GO:0048513 Animal organ development
Process GO:0048518 Positive regulation of biological process
Process GO:0048534 Hematopoietic or lymphoid organ development
Process GO:0048583 Regulation of response to stimulus
Process GO:0048731 System development
Process GO:0048856 Anatomical structure development
Process GO:0048869 Cellular developmental process
Process GO:0050776 Regulation of immune response
Process GO:0050789 Regulation of biological process
Process GO:0050794 Regulation of cellular process
Process GO:0050832 Defense response to fungus
Process GO:0050896 Response to stimulus
Process GO:0051239 Regulation of multicellular organismal process
Process GO:0051240 Positive regulation of multicellular organismal process
Process GO:0051707 Response to other organism
Process GO:0051716 Cellular response to stimulus
Process GO:0060255 Regulation of macromolecule metabolic process
Process GO:0061760 Antifungal innate immune response
Process GO:0065007 Biological regulation
Process GO:0098542 Defense response to other organism
Process GO:1903131 Mononuclear cell differentiation
Component GO:0001891 Phagocytic cup
Component GO:0005622 Intracellular anatomical structure
Component GO:0005737 Cytoplasm
Component GO:0005886 Plasma membrane
Component GO:0009897 External side of plasma membrane
Component GO:0009986 Cell surface
Component GO:0012506 Vesicle membrane
Component GO:0016020 Membrane
Component GO:0016021 Integral component of membrane
Component GO:0030139 Endocytic vesicle
Component GO:0030659 Cytoplasmic vesicle membrane
Component GO:0030666 Endocytic vesicle membrane
Component GO:0030670 Phagocytic vesicle membrane
Component GO:0031090 Organelle membrane
Component GO:0031224 Intrinsic component of membrane
Component GO:0031410 Cytoplasmic vesicle
Component GO:0031982 Vesicle
Component GO:0042995 Cell projection
Component GO:0043226 Organelle
Component GO:0043227 Membrane-bounded organelle
Component GO:0043229 Intracellular organelle
Component GO:0043231 Intracellular membrane-bounded organelle
Component GO:0045335 Phagocytic vesicle
Component GO:0071944 Cell periphery
Component GO:0097708 Intracellular vesicle
Component GO:0098552 Side of membrane
Component GO:0098588 Bounding membrane of organelle
Component GO:0110165 Cellular anatomical entity
Function GO:0005488 Binding
Function GO:0005509 Calcium ion binding
Function GO:0008289 Lipid binding
Function GO:0030246 Carbohydrate binding
Function GO:0038023 Signaling receptor activity
Function GO:0038187 Pattern recognition receptor activity
Function GO:0043167 Ion binding
Function GO:0043169 Cation binding
Function GO:0046872 Metal ion binding
Function GO:0051861 Glycolipid binding
Function GO:0060089 Molecular transducer activity
Function GO:0097367 Carbohydrate derivative binding

Pathway annotation


Category Term ID Term description
RCTM RNO-168249 Innate Immune System
RCTM RNO-168256 Immune System
RCTM RNO-5621480 Dectin-2 family
RCTM RNO-5621481 C-type lectin receptors (CLRs)
KEGG rno04625 C-type lectin receptor signaling pathway
KEGG rno05152 Tuberculosis

Expression profile of Clec4e in omics data



ID GSE100499
Title Exploring acupuncture mechanism in preconditioning of IRI
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM2685201 MX1 tissue: Myocardium gender: male 5.0028415
GSM2685202 MX2 tissue: Myocardium gender: female 4.9607368
GSM2685203 MX3 tissue: Myocardium gender: female 3.0441332
GSM2685204 MX4 tissue: Myocardium gender: male 4.1162305
GSM2685205 DZ1 tissue: Myocardium gender: male 4.4682207
GSM2685206 DZ2 tissue: Myocardium gender: male 3.6188216
GSM2685207 DZ3 tissue: Myocardium gender: female 3.4126089
GSM2685208 DZ4 tissue: Myocardium gender: female 3.6443737
GSM2685209 JJ1 tissue: Myocardium gender: male 4.182866
GSM2685210 JJ2 tissue: Myocardium gender: female 3.1820915
GSM2685211 JJ3 tissue: Myocardium gender: female 4.317441
GSM2685212 JJ4 tissue: Myocardium gender: male 3.8611147
GSM2685213 NG1 tissue: Myocardium gender: male 3.8855171
GSM2685214 NG2 tissue: Myocardium gender: female 5.8440256
GSM2685215 NG3 tissue: Myocardium gender: male 5.065816
GSM2685216 NG4 tissue: Myocardium gender: female 4.16861
GSM2685217 YL1 tissue: Myocardium gender: male 3.9405658
GSM2685218 YL2 tissue: Myocardium gender: male 5.0242653
GSM2685219 YL3 tissue: Myocardium gender: female 3.5907755
GSM2685220 YL4 tissue: Myocardium gender: female 5.2509174
GSM2685221 QC1 tissue: Myocardium gender: male 4.3212647
GSM2685222 QC2 tissue: Myocardium gender: male 3.7630215
GSM2685223 QC3 tissue: Myocardium gender: female 4.707291
GSM2685224 QC4 tissue: Myocardium gender: female 4.185073

ID GSE126106
Title Identification of candidate genes and pathways in dexmedetomidine-induced cardioprotection in the rat heart by bioinformatics analysis
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM3591631 Control1 treatment: administration of saline strain: Wistar Sex: male tissue: heart heart region: left ventricle 0.0
GSM3591632 Control2 treatment: administration of saline strain: Wistar Sex: male tissue: heart heart region: left ventricle 0.0
GSM3591633 Control3 treatment: administration of saline strain: Wistar Sex: male tissue: heart heart region: left ventricle 0.0
GSM3591634 Control4 treatment: administration of saline strain: Wistar Sex: male tissue: heart heart region: left ventricle 5.0
GSM3591635 Control5 treatment: administration of saline strain: Wistar Sex: male tissue: heart heart region: left ventricle 0.0
GSM3591636 DEX1 treatment: administration of dexmedetomidine strain: Wistar Sex: male tissue: heart heart region: left ventricle 4.0
GSM3591637 DEX2 treatment: administration of dexmedetomidine strain: Wistar Sex: male tissue: heart heart region: left ventricle 0.0
GSM3591638 DEX3 treatment: administration of dexmedetomidine strain: Wistar Sex: male tissue: heart heart region: left ventricle 10.0
GSM3591639 DEX4 treatment: administration of dexmedetomidine strain: Wistar Sex: male tissue: heart heart region: left ventricle 6.0
GSM3591640 DEX5 treatment: administration of dexmedetomidine strain: Wistar Sex: male tissue: heart heart region: left ventricle 7.0
GSM3591641 miRNA_Control1 treatment: administration of saline strain: Wistar Sex: male tissue: heart heart region: left ventricle
GSM3591642 miRNA_Control2 treatment: administration of saline strain: Wistar Sex: male tissue: heart heart region: left ventricle
GSM3591643 miRNA_Control3 treatment: administration of saline strain: Wistar Sex: male tissue: heart heart region: left ventricle
GSM3591644 miRNA_Control4 treatment: administration of saline strain: Wistar Sex: male tissue: heart heart region: left ventricle
GSM3591645 miRNA_Control5 treatment: administration of saline strain: Wistar Sex: male tissue: heart heart region: left ventricle
GSM3591646 miRNA_DEX1 treatment: administration of dexmedetomidine strain: Wistar Sex: male tissue: heart heart region: left ventricle
GSM3591647 miRNA_DEX2 treatment: administration of dexmedetomidine strain: Wistar Sex: male tissue: heart heart region: left ventricle
GSM3591648 miRNA_DEX3 treatment: administration of dexmedetomidine strain: Wistar Sex: male tissue: heart heart region: left ventricle
GSM3591649 miRNA_DEX4 treatment: administration of dexmedetomidine strain: Wistar Sex: male tissue: heart heart region: left ventricle
GSM3591650 miRNA_DEX5 treatment: administration of dexmedetomidine strain: Wistar Sex: male tissue: heart heart region: left ventricle

ID GSE136833
Title Effects of lidocaine on the expression of rat spinal cord
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM4058984 Control_1 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 2.187190144
GSM4058985 Control_2 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 2.003271513
GSM4058986 Control_3 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 2.087019049
GSM4058987 Lidocaine_1 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 4.878591807
GSM4058988 Lidocaine_2 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 4.548737849
GSM4058989 Lidocaine_3 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 2.847979854

ID GSE138454
Title Impact of inflammation on hepatic subcellular energetics in anesthetized rats
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM4108997 Sample 1 Isoflurane sepsis anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 11.0
GSM4108998 Sample 2 Isoflurane sepsis anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 12.0
GSM4108999 Sample 3 Isoflurane sepsis anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 23.0
GSM4109000 Sample 4 Isoflurane sepsis anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 12.0
GSM4109001 Sample 5 Isoflurane control anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 7.0
GSM4109002 Sample 6 Isoflurane control anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 8.0
GSM4109003 Sample 7 Isoflurane control anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 6.0
GSM4109004 Sample 8 Isoflurane control anesthetic background: Isoflurane strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 11.0
GSM4109005 Sample9 Propofol sepsis anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 20.0
GSM4109006 Sample10 Propofol sepsis anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 20.0
GSM4109007 Sample11 Propofol sepsis anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 7.0
GSM4109008 Sample12 Propofol sepsis anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: sepsis gender: male 33.0
GSM4109009 Sample13 Propofol control anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 11.0
GSM4109010 Sample14 Propofol control anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 1.0
GSM4109011 Sample 15 Propofol control anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 7.0
GSM4109012 Sample16 Propofol control anesthetic background: Propofol strain: Sprague-Dawley age: 10 weeks old sepsis/control: control gender: male 6.0

ID GSE139220
Title Expression data from sevoflurane anesthesia treated rat
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM4134285 Brain_Control_rep1 strain: Sprague-Dawley age: 18-month old treatment: control tissue: hippocampus 4.60717
GSM4134286 Brain_Control_rep2 strain: Sprague-Dawley age: 18-month old treatment: control tissue: hippocampus 4.671986
GSM4134287 Brain_Control_rep3 strain: Sprague-Dawley age: 18-month old treatment: control tissue: hippocampus 4.70726
GSM4134288 Brain_Sevoflurane_rep1 strain: Sprague-Dawley age: 18-month old treatment: sevoflurane anesthesia tissue: hippocampus 4.838123
GSM4134289 Brain_Sevoflurane_rep2 strain: Sprague-Dawley age: 18-month old treatment: sevoflurane anesthesia tissue: hippocampus 4.564044
GSM4134290 Brain_Sevoflurane_rep3 strain: Sprague-Dawley age: 18-month old treatment: sevoflurane anesthesia tissue: hippocampus 4.776978

ID GSE143895
Title GPR160 de-orphanization reveals critical roles in neuropathic pain in rodents
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM4276356 dhsc01 strain: Sprague Dawley tissue: DHSC treatment: CCI 0.425
GSM4276357 dhsc03 strain: Sprague Dawley tissue: DHSC treatment: CCI 4.657
GSM4276358 dhsc05 strain: Sprague Dawley tissue: DHSC treatment: CCI 2.078
GSM4276359 dhsc13 strain: Sprague Dawley tissue: DHSC treatment: SHAM 0.0
GSM4276360 dhsc15 strain: Sprague Dawley tissue: DHSC treatment: SHAM 0.0

ID GSE192399
Title Gene expression of brain regions activated by sevoflurane and propofol
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM5746332 LHb, Sevoflurane, 60mins brain region: the lateral habenula (LHb) treatment: Sevoflurane 5.50729
GSM5746333 LHb, O2, 60mins brain region: the lateral habenula (LHb) treatment: O2 5.52332
GSM5746334 MHb, Sevoflurane, 60mins brain region: the medial habenula (MHb) treatment: Sevoflurane 5.78366
GSM5746335 MHb, O2, 60mins brain region: the medial habenula (MHb) treatment: O2 5.57811
GSM5746336 Sol, Sevoflurane, 60mins brain region: the solitary nucleus (Sol) treatment: Sevoflurane 5.35742
GSM5746337 Sol, O2, 60mins brain region: the solitary nucleus (Sol) treatment: O2 5.17322
GSM5746338 Mve, Sevoflurane, 60mins brain region: the medial vestibular nucleus (MVe) treatment: Sevoflurane 5.96367
GSM5746339 Mve, O2, 60mins brain region: the medial vestibular nucleus (MVe) treatment: O2 6.66168
GSM5746340 LHb, Propofol, 60mins brain region: the lateral habenula (LHb) treatment: Propofol 5.4382
GSM5746341 LHb, Intralipos, 60mins brain region: the lateral habenula (LHb) treatment: Intralipos 5.53577
GSM5746342 MHb, Propofol, 60mins brain region: the medial habenula (MHb) treatment: Propofol 5.31605
GSM5746343 MHb, Intralipos, 60mins brain region: the medial habenula (MHb) treatment: Intralipos 4.96238
GSM5746344 Sol, Propofol, 60mins brain region: the solitary nucleus (Sol) treatment: Propofol 5.70618
GSM5746345 Sol, Intralipos, 60mins brain region: the solitary nucleus (Sol) treatment: Intralipos 5.45907
GSM5746346 MVe, Propofol, 60mins brain region: the medial vestibular nucleus (MVe) treatment: Propofol 5.17895
GSM5746347 MVe, Intralipos, 60mins brain region: the medial vestibular nucleus (MVe) treatment: Intralipos 5.6952

ID GSE21258
Title Transcript Profiling of Spinal Dorsal Horn in Response to Electroacupuncture on Rats at 1h
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM531353 2Hz_HR_1h_DH1 rat time point: 1h strain: Sprague-Dawley tissue type: spinal dorsal horn frequency: 2Hz group: high responder (HR) rats;strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation. 0.676
GSM531354 2Hz_HR_1h_DH2 rat time point: 1h strain: Sprague-Dawley tissue type: spinal dorsal horn frequency: 2Hz group: high responder (HR) rats;strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation. 0.637
GSM531355 2Hz_HR_1h_DH3 rat time point: 1h strain: Sprague-Dawley tissue type: spinal dorsal horn frequency: 2Hz group: high responder (HR) rats;strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation. 0.719
GSM531356 2Hz_HR_1h_DH4 rat time point: 1h strain: Sprague-Dawley tissue type: spinal dorsal horn frequency: 2Hz group: high responder (HR) rats;strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation. 1.036
GSM531357 2Hz_HR_1h_DH5 rat time point: 1h strain: Sprague-Dawley tissue type: spinal dorsal horn frequency: 2Hz group: high responder (HR) rats;strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation. 0.787
GSM531358 2Hz_LR_1h_DH1 rat time point: 1h strain: Sprague-Dawley tissue type: spinal dorsal horn frequency: 2Hz group: low responder (LR) rats;strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation. 0.862
GSM531359 2Hz_LR_1h_DH2 rat time point: 1h strain: Sprague-Dawley tissue type: spinal dorsal horn frequency: 2Hz group: low responder (LR) rats;strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation. 0.324
GSM531360 2Hz_LR_1h_DH3 rat time point: 1h strain: Sprague-Dawley tissue type: spinal dorsal horn frequency: 2Hz group: low responder (LR) rats;strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation. 0.667
GSM531361 2Hz_LR_1h_DH4 rat time point: 1h strain: Sprague-Dawley tissue type: spinal dorsal horn frequency: 2Hz group: low responder (LR) rats;strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation. 0.493
GSM531362 100Hz_HR_1h_DH1 rat time point: 1h strain: Sprague-Dawley tissue type: spinal dorsal horn frequency: 100Hz group: high responder (HR) rats;strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation. 1.014
GSM531363 100Hz_HR_1h_DH2 rat time point: 1h strain: Sprague-Dawley tissue type: spinal dorsal horn frequency: 100Hz group: high responder (HR) rats;strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation. 0.727
GSM531364 100Hz_HR_1h_DH3 rat time point: 1h strain: Sprague-Dawley tissue type: spinal dorsal horn frequency: 100Hz group: high responder (HR) rats;strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation. 0.903
GSM531365 100Hz_HR_1h_DH4 rat time point: 1h strain: Sprague-Dawley tissue type: spinal dorsal horn frequency: 100Hz group: high responder (HR) rats;strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation. 0.554
GSM531366 100Hz_HR_1h_DH5 rat time point: 1h strain: Sprague-Dawley tissue type: spinal dorsal horn frequency: 100Hz group: high responder (HR) rats;strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation. 0.967
GSM531367 100Hz_LR_1h_DH1 rat time point: 1h;strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation. strain: Sprague-Dawley tissue type: spinal dorsal horn frequency: 100Hz group: low responder (LR) rats 0.182
GSM531368 100Hz_LR_1h_DH2 rat time point: 1h strain: Sprague-Dawley tissue type: spinal dorsal horn frequency: 100Hz group: low responder (LR) rats;strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation. -0.159
GSM531369 100Hz_LR_1h_DH3 rat time point: 1h strain: Sprague-Dawley tissue type: spinal dorsal horn frequency: 100Hz group: low responder (LR) rats;strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation. 0.488
GSM531370 100Hz_LR_1h_DH4 rat time point: 1h strain: Sprague-Dawley tissue type: spinal dorsal horn frequency: 100Hz group: low responder (LR) rats;strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation. 0.73
GSM531371 100Hz_LR_1h_DH5 rat time point: 1h strain: Sprague-Dawley tissue type: spinal dorsal horn frequency: 100Hz group: low responder (LR) rats;strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation. 0.41

ID GSE21733
Title Transcript Profiling of Spinal Dorsal Horn in Response to Electroacupuncture on Rats at 24h
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM542196 2Hz_HR_24h_DH1 rat time point: 24h strain: Sprague-Dawley electroacupuncture frequency: 2Hz group: high responder (HR) rats tissue type: dorsal horn (DH); strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation tissue type: dorsal horn (DH) -0.075592285
GSM542197 2Hz_HR_24h_DH2 rat time point: 24h strain: Sprague-Dawley electroacupuncture frequency: 2Hz group: high responder (HR) rats tissue type: dorsal horn (DH); strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation tissue type: dorsal horn (DH) 0.903043808
GSM542198 2Hz_HR_24h_DH3 rat time point: 24h strain: Sprague-Dawley electroacupuncture frequency: 2Hz group: high responder (HR) rats tissue type: dorsal horn (DH); strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation tissue type: dorsal horn (DH) -0.744232274
GSM542199 2Hz_HR_24h_DH4 rat time point: 24h strain: Sprague-Dawley electroacupuncture frequency: 2Hz group: high responder (HR) rats tissue type: dorsal horn (DH); strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation tissue type: dorsal horn (DH) 0.501031617
GSM542200 2Hz_HR_24h_DH5 rat time point: 24h strain: Sprague-Dawley electroacupuncture frequency: 2Hz group: high responder (HR) rats tissue type: dorsal horn (DH);strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation tissue type: dorsal horn (DH) 0.036606288
GSM542201 2Hz_LR_24h_DH1 rat time point: 24h strain: Sprague-Dawley electroacupuncture frequency: 2Hz group: low responder (LR) rats tissue type: dorsal horn (DH);strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation tissue type: dorsal horn (DH) 0.946042717
GSM542202 2Hz_LR_24h_DH2 rat time point: 24h strain: Sprague-Dawley electroacupuncture frequency: 2Hz group: low responder (LR) rats tissue type: dorsal horn (DH);strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation tissue type: dorsal horn (DH) 0.463496688
GSM542203 2Hz_LR_24h_DH3 rat time point: 24h strain: Sprague-Dawley electroacupuncture frequency: 2Hz group: low responder (LR) rats tissue type: dorsal horn (DH);strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation tissue type: dorsal horn (DH) 1.129570497
GSM542204 2Hz_LR_24h_DH4 rat time point: 24h strain: Sprague-Dawley electroacupuncture frequency: 2Hz group: low responder (LR) rats tissue type: dorsal horn (DH);strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation tissue type: dorsal horn (DH) 1.013146406
GSM542205 2Hz_LR_24h_DH5 rat time point: 24h strain: Sprague-Dawley electroacupuncture frequency: 2Hz group: low responder (LR) rats tissue type: dorsal horn (DH);strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation tissue type: dorsal horn (DH) -0.740310283
GSM542206 100Hz_HR_24h_DH1 rat time point: 24h strain: Sprague-Dawley electroacupuncture frequency: 100Hz group: high responder (HR) rats tissue type: dorsal horn (DH);strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation tissue type: dorsal horn (DH) -0.580328195
GSM542207 100Hz_HR_24h_DH2 rat time point: 24h strain: Sprague-Dawley electroacupuncture frequency: 100Hz group: high responder (HR) rats tissue type: dorsal horn (DH);strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation tissue type: dorsal horn (DH) -0.115262632
GSM542208 100Hz_HR_24h_DH3 rat time point: 24h strain: Sprague-Dawley electroacupuncture frequency: 100Hz group: high responder (HR) rats tissue type: dorsal horn (DH);strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation tissue type: dorsal horn (DH) -0.572074211
GSM542209 100Hz_HR_24h_DH4 rat time point: 24h strain: Sprague-Dawley electroacupuncture frequency: 100Hz group: high responder (HR) rats tissue type: dorsal horn (DH);strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation tissue type: dorsal horn (DH) 0.564055346
GSM542210 100Hz_HR_24h_DH5 rat time point: 24h strain: Sprague-Dawley electroacupuncture frequency: 100Hz group: high responder (HR) rats tissue type: dorsal horn (DH);strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation tissue type: dorsal horn (DH) 0.686862028
GSM542211 100Hz_LR_24h_DH1 rat time point: 24h strain: Sprague-Dawley electroacupuncture frequency: 100Hz group: low responder (LR) rats tissue type: dorsal horn (DH);strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation tissue type: dorsal horn (DH) 0.690119839
GSM542212 100Hz_LR_24h_DH2 rat time point: 24h strain: Sprague-Dawley electroacupuncture frequency: 100Hz group: low responder (LR) rats tissue type: dorsal horn (DH);strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation tissue type: dorsal horn (DH) 0.248728283
GSM542213 100Hz_LR_24h_DH3 rat time point: 24h strain: Sprague-Dawley electroacupuncture frequency: 100Hz group: low responder (LR) rats tissue type: dorsal horn (DH);strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation tissue type: dorsal horn (DH) -0.016025089
GSM542214 100Hz_LR_24h_DH4 rat time point: 24h strain: Sprague-Dawley electroacupuncture frequency: 100Hz group: low responder (LR) rats tissue type: dorsal horn (DH);strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation tissue type: dorsal horn (DH) -0.797882885
GSM542215 100Hz_LR_24h_DH5 rat time point: 24h strain: Sprague-Dawley electroacupuncture frequency: 100Hz group: low responder (LR) rats tissue type: dorsal horn (DH);strain: Sprague-Dawley reference: rats sacrificed after stayed in their home cages without receiving electroacupuncture stimulation tissue type: dorsal horn (DH) 1.113606652

ID GSE30365
Title Transcript Profiling of Arcuate Nucleus in Response to Electroacupuncture on Rats
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM753495 2Hz_HR_Arc1 rat strain: Sprague-Dawley electroacupuncture: 2Hz responder: high;strain: Sprague-Dawley sample type: control 0.0
GSM753496 2Hz_HR_Arc2 rat strain: Sprague-Dawley electroacupuncture: 2Hz responder: high;strain: Sprague-Dawley sample type: control 0.0
GSM753497 2Hz_HR_Arc3 rat strain: Sprague-Dawley electroacupuncture: 2Hz responder: high;strain: Sprague-Dawley sample type: control 0.0
GSM753498 2Hz_NR_Arc1 rat strain: Sprague-Dawley electroacupuncture: 2Hz responder: no; strain: Sprague-Dawley sample type: control 0.0
GSM753499 2Hz_NR_Arc2 rat strain: Sprague-Dawley electroacupuncture: 2Hz responder: no; strain: Sprague-Dawley sample type: control 0.0
GSM753500 2Hz_NR_Arc3 rat strain: Sprague-Dawley electroacupuncture: 2Hz responder: no; strain: Sprague-Dawley sample type: control 0.0
GSM753501 100Hz_HR_Arc1 rat strain: Sprague-Dawley electroacupuncture: 100Hz responder: high;strain: Sprague-Dawley sample type: control -0.6772
GSM753502 100Hz_HR_Arc2 rat strain: Sprague-Dawley electroacupuncture: 100Hz responder: high;strain: Sprague-Dawley sample type: control 0.0
GSM753503 100Hz_HR_Arc3 rat strain: Sprague-Dawley electroacupuncture: 100Hz responder: high;strain: Sprague-Dawley sample type: control 0.5735
GSM753504 100Hz_NR_Arc1 rat strain: Sprague-Dawley electroacupuncture: 100Hz responder: no;strain: Sprague-Dawley sample type: control -1.848
GSM753505 100Hz_NR_Arc2 rat strain: Sprague-Dawley electroacupuncture: 100Hz responder: no;strain: Sprague-Dawley sample type: control 0.0
GSM753506 100Hz_NR_Arc3 rat strain: Sprague-Dawley electroacupuncture: 100Hz responder: no;strain: Sprague-Dawley sample type: control 0.0

ID GSE53897
Title Genome-wide analysis of dorsal root ganglion (DRG) gene expression after morphine or oxycodone treatment
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM1303240 DRG RVM1 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.64528
GSM1303241 DRG RVM2 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.743217
GSM1303242 DRG RVM3 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.760195
GSM1303243 DRG RVM7 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.679418
GSM1303244 DRG RVOx2 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.833022
GSM1303245 DRG RVOx3 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.556578
GSM1303246 DRG RVOx5 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.727714
GSM1303247 DRG RVOx7 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.796685
GSM1303248 DRG RVS4 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.838288
GSM1303249 DRG RVS5 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.61431
GSM1303250 DRG RVS6 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.679547
GSM1303251 DRG RVS7 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.718521
GSM1303252 DRG RSM1 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.711758
GSM1303253 DRG RSM2 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.751981
GSM1303254 DRG RSM4 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.68844
GSM1303255 DRG RSM5 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.687442
GSM1303256 DRG RSOx1 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.635727
GSM1303257 DRG RSOx2 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.785876
GSM1303258 DRG RSOx3 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.622757
GSM1303259 DRG RSOx4 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.623827
GSM1303260 DRG RSS1 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.671149
GSM1303261 DRG RSS2 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.802926
GSM1303262 DRG RSS3 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.724983
GSM1303263 DRG RSS6 strain: sprague-dawley age: 3 months tissue: dorsal root ganglion 5.826091

ID GSE58803
Title Transcript Profiling of Periaqueductal Gray in Response to Electroacupuncture on Rats
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM1419812 2Hz_HR_1h_PAG1 rat strain: Sprague-Dawley tissue: PAG treatment: 2Hz electroacupuncture responder type: high responder(HR) time: 1h;strain: Sprague-Dawley treatment: control tissue: PAG -0.085807938
GSM1419813 2Hz_HR_1h_PAG2 rat strain: Sprague-Dawley tissue: PAG treatment: 2Hz electroacupuncture responder type: high responder(HR) time: 1h;strain: Sprague-Dawley treatment: control tissue: PAG 0.309399826
GSM1419814 2Hz_HR_1h_PAG3 rat strain: Sprague-Dawley tissue: PAG treatment: 2Hz electroacupuncture responder type: high responder(HR) time: 1h; strain: Sprague-Dawley treatment: control tissue: PAG 0.073273954
GSM1419815 2Hz_HR_1h_PAG4 rat strain: Sprague-Dawley tissue: PAG treatment: 2Hz electroacupuncture responder type: high responder(HR) time: 1h;strain: Sprague-Dawley treatment: control tissue: PAG -0.064725415
GSM1419816 2Hz_HR_1h_PAG5 rat strain: Sprague-Dawley tissue: PAG treatment: 2Hz electroacupuncture responder type: high responder(HR) time: 1h;strain: Sprague-Dawley treatment: control tissue: PAG -0.011213742
GSM1419817 2Hz_NR_1h_PAG1 rat strain: Sprague-Dawley tissue: PAG treatment: 2Hz electroacupuncture responder type: low responder(NR) time: 1h;strain: Sprague-Dawley treatment: control tissue: PAG 0.113754526
GSM1419818 2Hz_NR_1h_PAG2 rat strain: Sprague-Dawley tissue: PAG treatment: 2Hz electroacupuncture responder type: low responder(NR) time: 1h;strain: Sprague-Dawley treatment: control tissue: PAG -0.295700337
GSM1419819 2Hz_NR_1h_PAG3 rat strain: Sprague-Dawley tissue: PAG treatment: 2Hz electroacupuncture responder type: low responder(NR) time: 1h;strain: Sprague-Dawley treatment: control tissue: PAG 0.06203515
GSM1419820 2Hz_NR_1h_PAG4 rat strain: Sprague-Dawley tissue: PAG treatment: 2Hz electroacupuncture responder type: low responder(NR) time: 1h;strain: Sprague-Dawley treatment: control tissue: PAG 1.164320716
GSM1419821 100Hz_HR_1h_PAG1 rat strain: Sprague-Dawley tissue: PAG treatment: 100Hz electroacupuncture responder type: high responder(HR) time: 1h;strain: Sprague-Dawley treatment: control tissue: PAG -0.119590998
GSM1419822 100Hz_HR_1h_PAG2 rat strain: Sprague-Dawley tissue: PAG treatment: 100Hz electroacupuncture responder type: high responder(HR) time: 1h;strain: Sprague-Dawley treatment: control tissue: PAG -0.056052959
GSM1419823 100Hz_HR_1h_PAG3 rat strain: Sprague-Dawley tissue: PAG treatment: 100Hz electroacupuncture responder type: high responder(HR) time: 1h;strain: Sprague-Dawley treatment: control tissue: PAG -0.10371113
GSM1419824 100Hz_HR_1h_PAG4 rat strain: Sprague-Dawley tissue: PAG treatment: 100Hz electroacupuncture responder type: high responder(HR) time: 1h;strain: Sprague-Dawley treatment: control tissue: PAG -0.101405772
GSM1419825 100Hz_HR_1h_PAG5 rat strain: Sprague-Dawley tissue: PAG treatment: 100Hz electroacupuncture responder type: high responder(HR) time: 1h;strain: Sprague-Dawley treatment: control tissue: PAG 0.022842739
GSM1419826 100Hz_NR_1h_PAG1 rat strain: Sprague-Dawley tissue: PAG treatment: 100Hz electroacupuncture responder type: low responder(NR) time: 1h; strain: Sprague-Dawley treatment: control tissue: PAG 0.058561285
GSM1419827 100Hz_NR_1h_PAG2 rat strain: Sprague-Dawley tissue: PAG treatment: 100Hz electroacupuncture responder type: low responder(NR) time: 1h; strain: Sprague-Dawley treatment: control tissue: PAG 0.564161362
GSM1419828 100Hz_NR_1h_PAG3 rat strain: Sprague-Dawley tissue: PAG treatment: 100Hz electroacupuncture responder type: low responder(NR) time: 1h; strain: Sprague-Dawley treatment: control tissue: PAG 0.066711404
GSM1419829 100Hz_NR_1h_PAG4 rat strain: Sprague-Dawley tissue: PAG treatment: 100Hz electroacupuncture responder type: low responder(NR) time: 1h;strain: Sprague-Dawley treatment: control tissue: PAG -0.288905949
GSM1419830 100Hz_NR_1h_PAG5 rat strain: Sprague-Dawley tissue: PAG treatment: 100Hz electroacupuncture responder type: low responder(NR) time: 1h;strain: Sprague-Dawley treatment: control tissue: PAG -0.084831717
GSM1419831 2Hz_HR_24h_PAG1 rat strain: Sprague-Dawley tissue: PAG treatment: 2Hz electroacupuncture responder type: high responder(HR) time: 24h;strain: Sprague-Dawley treatment: control tissue: PAG -0.139811983
GSM1419832 2Hz_HR_24h_PAG2 rat strain: Sprague-Dawley tissue: PAG treatment: 2Hz electroacupuncture responder type: high responder(HR) time: 24h;strain: Sprague-Dawley treatment: control tissue: PAG 0.208476019
GSM1419833 2Hz_HR_24h_PAG3 rat strain: Sprague-Dawley tissue: PAG treatment: 2Hz electroacupuncture responder type: high responder(HR) time: 24h; strain: Sprague-Dawley treatment: control tissue: PAG 0.004368796
GSM1419834 2Hz_HR_24h_PAG4 rat strain: Sprague-Dawley tissue: PAG treatment: 2Hz electroacupuncture responder type: high responder(HR) time: 24h;strain: Sprague-Dawley treatment: control tissue: PAG -0.360423793
GSM1419835 2Hz_HR_24h_PAG5 rat strain: Sprague-Dawley tissue: PAG treatment: 2Hz electroacupuncture responder type: high responder(HR) time: 24h;strain: Sprague-Dawley treatment: control tissue: PAG -0.405744491
GSM1419836 2Hz_NR_24h_PAG1 rat strain: Sprague-Dawley tissue: PAG treatment: 2Hz electroacupuncture responder type: low responder(NR) time: 24h;strain: Sprague-Dawley treatment: control tissue: PAG 0.275087969
GSM1419837 2Hz_NR_24h_PAG2 rat strain: Sprague-Dawley tissue: PAG treatment: 2Hz electroacupuncture responder type: low responder(NR) time: 24h;strain: Sprague-Dawley treatment: control tissue: PAG -0.188909053
GSM1419838 2Hz_NR_24h_PAG3 rat strain: Sprague-Dawley tissue: PAG treatment: 2Hz electroacupuncture responder type: low responder(NR) time: 24h;strain: Sprague-Dawley treatment: control tissue: PAG 0.109878277
GSM1419839 2Hz_NR_24h_PAG4 rat strain: Sprague-Dawley tissue: PAG treatment: 2Hz electroacupuncture responder type: low responder(NR) time: 24h;strain: Sprague-Dawley treatment: control tissue: PAG 0.038884547
GSM1419840 2Hz_NR_24h_PAG5 rat strain: Sprague-Dawley tissue: PAG treatment: 2Hz electroacupuncture responder type: low responder(NR) time: 24h;strain: Sprague-Dawley treatment: control tissue: PAG -0.17144909
GSM1419841 100Hz_HR_24h_PAG1 rat strain: Sprague-Dawley tissue: PAG treatment: 100Hz electroacupuncture responder type: high responder(HR) time: 24h;strain: Sprague-Dawley treatment: control tissue: PAG 0.181580469
GSM1419842 100Hz_HR_24h_PAG2 rat strain: Sprague-Dawley tissue: PAG treatment: 100Hz electroacupuncture responder type: high responder(HR) time: 24h;strain: Sprague-Dawley treatment: control tissue: PAG 0.479385808
GSM1419843 100Hz_HR_24h_PAG3 rat strain: Sprague-Dawley tissue: PAG treatment: 100Hz electroacupuncture responder type: high responder(HR) time: 24h;strain: Sprague-Dawley treatment: control tissue: PAG 0.138576848
GSM1419844 100Hz_HR_24h_PAG4 rat strain: Sprague-Dawley tissue: PAG treatment: 100Hz electroacupuncture responder type: high responder(HR) time: 24h;strain: Sprague-Dawley treatment: control tissue: PAG 0.271510251
GSM1419845 100Hz_HR_24h_PAG5 rat strain: Sprague-Dawley tissue: PAG treatment: 100Hz electroacupuncture responder type: high responder(HR) time: 24h;strain: Sprague-Dawley treatment: control tissue: PAG 0.110078983
GSM1419846 100Hz_NR_24h_PAG1 rat strain: Sprague-Dawley tissue: PAG treatment: 100Hz electroacupuncture responder type: low responder(NR) time: 24h;strain: Sprague-Dawley treatment: control tissue: PAG -0.240105276
GSM1419847 100Hz_NR_24h_PAG2 rat strain: Sprague-Dawley tissue: PAG treatment: 100Hz electroacupuncture responder type: low responder(NR) time: 24h;strain: Sprague-Dawley treatment: control tissue: PAG -0.379076135
GSM1419848 100Hz_NR_24h_PAG3 rat strain: Sprague-Dawley tissue: PAG treatment: 100Hz electroacupuncture responder type: low responder(NR) time: 24h;strain: Sprague-Dawley treatment: control tissue: PAG -0.074239126
GSM1419849 100Hz_NR_24h_PAG4 rat strain: Sprague-Dawley tissue: PAG treatment: 100Hz electroacupuncture responder type: low responder(NR) time: 24h;strain: Sprague-Dawley treatment: control tissue: PAG -0.313008723
GSM1419850 100Hz_NR_24h_PAG5 rat strain: Sprague-Dawley tissue: PAG treatment: 100Hz electroacupuncture responder type: low responder(NR) time: 24h;strain: Sprague-Dawley treatment: control tissue: PAG -0.146759682