Gene symbol: Mef2c

Also known as: RGD1563119

Organism: Rattus norvegicus

Summary: Enables DNA binding activity and DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in several processes, including cellular response to retinoic acid; dentate gyrus development; and transdifferentiation. Located in nucleus and sarcomere. Used to study myocardial infarction. Biomarker of status epilepticus. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 20. Orthologous to human MEF2C (myocyte enhancer factor 2C). [provided by Alliance of Genome Resources, Apr 2022]

NCBI gene ID: 499497 Ensembl:ENSRNOG00000033134 AllianceGenome:RGD:1563119


GO Annotation


Category Term ID Term description
Process GO:0000122 Negative regulation of transcription by RNA polymerase II
Process GO:0000165 MAPK cascade
Process GO:0000902 Cell morphogenesis
Process GO:0000904 Cell morphogenesis involved in differentiation
Process GO:0001501 Skeletal system development
Process GO:0001503 Ossification
Process GO:0001505 Regulation of neurotransmitter levels
Process GO:0001568 Blood vessel development
Process GO:0001649 Osteoblast differentiation
Process GO:0001655 Urogenital system development
Process GO:0001678 Cellular glucose homeostasis
Process GO:0001709 Cell fate determination
Process GO:0001764 Neuron migration
Process GO:0001775 Cell activation
Process GO:0001776 Leukocyte homeostasis
Process GO:0001782 B cell homeostasis
Process GO:0001822 Kidney development
Process GO:0001932 Regulation of protein phosphorylation
Process GO:0001934 Positive regulation of protein phosphorylation
Process GO:0001936 Regulation of endothelial cell proliferation
Process GO:0001937 Negative regulation of endothelial cell proliferation
Process GO:0001944 Vasculature development
Process GO:0001947 Heart looping
Process GO:0001958 Endochondral ossification
Process GO:0001974 Blood vessel remodeling
Process GO:0002009 Morphogenesis of an epithelium
Process GO:0002062 Chondrocyte differentiation
Process GO:0002237 Response to molecule of bacterial origin
Process GO:0002250 Adaptive immune response
Process GO:0002253 Activation of immune response
Process GO:0002260 Lymphocyte homeostasis
Process GO:0002376 Immune system process
Process GO:0002429 Immune response-activating cell surface receptor signaling pathway
Process GO:0002460 Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
Process GO:0002467 Germinal center formation
Process GO:0002520 Immune system development
Process GO:0002521 Leukocyte differentiation
Process GO:0002573 Myeloid leukocyte differentiation
Process GO:0002634 Regulation of germinal center formation
Process GO:0002682 Regulation of immune system process
Process GO:0002684 Positive regulation of immune system process
Process GO:0002694 Regulation of leukocyte activation
Process GO:0002696 Positive regulation of leukocyte activation
Process GO:0002757 Immune response-activating signal transduction
Process GO:0002764 Immune response-regulating signaling pathway
Process GO:0002768 Immune response-regulating cell surface receptor signaling pathway
Process GO:0002819 Regulation of adaptive immune response
Process GO:0002822 Regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
Process GO:0002931 Response to ischemia
Process GO:0003002 Regionalization
Process GO:0003007 Heart morphogenesis
Process GO:0003008 System process
Process GO:0003012 Muscle system process
Process GO:0003128 Heart field specification
Process GO:0003138 Primary heart field specification
Process GO:0003139 Secondary heart field specification
Process GO:0003143 Embryonic heart tube morphogenesis
Process GO:0003151 Outflow tract morphogenesis
Process GO:0003170 Heart valve development
Process GO:0003172 Sinoatrial valve development
Process GO:0003179 Heart valve morphogenesis
Process GO:0003185 Sinoatrial valve morphogenesis
Process GO:0003205 Cardiac chamber development
Process GO:0003206 Cardiac chamber morphogenesis
Process GO:0003207 Cardiac chamber formation
Process GO:0003208 Cardiac ventricle morphogenesis
Process GO:0003211 Cardiac ventricle formation
Process GO:0003231 Cardiac ventricle development
Process GO:0003299 Muscle hypertrophy in response to stress
Process GO:0003300 Cardiac muscle hypertrophy
Process GO:0006355 Regulation of transcription, DNA-templated
Process GO:0006357 Regulation of transcription by RNA polymerase II
Process GO:0006915 Apoptotic process
Process GO:0006935 Chemotaxis
Process GO:0006950 Response to stress
Process GO:0006955 Immune response
Process GO:0006959 Humoral immune response
Process GO:0007154 Cell communication
Process GO:0007165 Signal transduction
Process GO:0007166 Cell surface receptor signaling pathway
Process GO:0007267 Cell-cell signaling
Process GO:0007268 Chemical synaptic transmission
Process GO:0007275 Multicellular organism development
Process GO:0007368 Determination of left/right symmetry
Process GO:0007389 Pattern specification process
Process GO:0007399 Nervous system development
Process GO:0007409 Axonogenesis
Process GO:0007411 Axon guidance
Process GO:0007417 Central nervous system development
Process GO:0007420 Brain development
Process GO:0007507 Heart development
Process GO:0007517 Muscle organ development
Process GO:0007519 Skeletal muscle tissue development
Process GO:0007521 Muscle cell fate determination
Process GO:0007584 Response to nutrient
Process GO:0007610 Behavior
Process GO:0007611 Learning or memory
Process GO:0008152 Metabolic process
Process GO:0008219 Cell death
Process GO:0008283 Cell population proliferation
Process GO:0008284 Positive regulation of cell population proliferation
Process GO:0008285 Negative regulation of cell population proliferation
Process GO:0009410 Response to xenobiotic stimulus
Process GO:0009605 Response to external stimulus
Process GO:0009607 Response to biotic stimulus
Process GO:0009617 Response to bacterium
Process GO:0009653 Anatomical structure morphogenesis
Process GO:0009719 Response to endogenous stimulus
Process GO:0009725 Response to hormone
Process GO:0009743 Response to carbohydrate
Process GO:0009746 Response to hexose
Process GO:0009749 Response to glucose
Process GO:0009790 Embryo development
Process GO:0009792 Embryo development ending in birth or egg hatching
Process GO:0009799 Specification of symmetry
Process GO:0009855 Determination of bilateral symmetry
Process GO:0009887 Animal organ morphogenesis
Process GO:0009888 Tissue development
Process GO:0009889 Regulation of biosynthetic process
Process GO:0009890 Negative regulation of biosynthetic process
Process GO:0009891 Positive regulation of biosynthetic process
Process GO:0009892 Negative regulation of metabolic process
Process GO:0009893 Positive regulation of metabolic process
Process GO:0009966 Regulation of signal transduction
Process GO:0009967 Positive regulation of signal transduction
Process GO:0009987 Cellular process
Process GO:0009991 Response to extracellular stimulus
Process GO:0010033 Response to organic substance
Process GO:0010035 Response to inorganic substance
Process GO:0010038 Response to metal ion
Process GO:0010092 Specification of animal organ identity
Process GO:0010243 Response to organonitrogen compound
Process GO:0010467 Gene expression
Process GO:0010468 Regulation of gene expression
Process GO:0010469 Regulation of signaling receptor activity
Process GO:0010556 Regulation of macromolecule biosynthetic process
Process GO:0010557 Positive regulation of macromolecule biosynthetic process
Process GO:0010558 Negative regulation of macromolecule biosynthetic process
Process GO:0010562 Positive regulation of phosphorus metabolic process
Process GO:0010594 Regulation of endothelial cell migration
Process GO:0010596 Negative regulation of endothelial cell migration
Process GO:0010604 Positive regulation of macromolecule metabolic process
Process GO:0010605 Negative regulation of macromolecule metabolic process
Process GO:0010611 Regulation of cardiac muscle hypertrophy
Process GO:0010613 Positive regulation of cardiac muscle hypertrophy
Process GO:0010628 Positive regulation of gene expression
Process GO:0010629 Negative regulation of gene expression
Process GO:0010632 Regulation of epithelial cell migration
Process GO:0010633 Negative regulation of epithelial cell migration
Process GO:0010646 Regulation of cell communication
Process GO:0010647 Positive regulation of cell communication
Process GO:0010692 Regulation of alkaline phosphatase activity
Process GO:0010694 Positive regulation of alkaline phosphatase activity
Process GO:0010921 Regulation of phosphatase activity
Process GO:0010922 Positive regulation of phosphatase activity
Process GO:0010941 Regulation of cell death
Process GO:0010942 Positive regulation of cell death
Process GO:0012501 Programmed cell death
Process GO:0014033 Neural crest cell differentiation
Process GO:0014070 Response to organic cyclic compound
Process GO:0014706 Striated muscle tissue development
Process GO:0014742 Positive regulation of muscle hypertrophy
Process GO:0014743 Regulation of muscle hypertrophy
Process GO:0014887 Cardiac muscle adaptation
Process GO:0014888 Striated muscle adaptation
Process GO:0014896 Muscle hypertrophy
Process GO:0014897 Striated muscle hypertrophy
Process GO:0014898 Cardiac muscle hypertrophy in response to stress
Process GO:0014902 Myotube differentiation
Process GO:0014910 Regulation of smooth muscle cell migration
Process GO:0014912 Negative regulation of smooth muscle cell migration
Process GO:0016043 Cellular component organization
Process GO:0016477 Cell migration
Process GO:0019219 Regulation of nucleobase-containing compound metabolic process
Process GO:0019220 Regulation of phosphate metabolic process
Process GO:0019222 Regulation of metabolic process
Process GO:0019725 Cellular homeostasis
Process GO:0021537 Telencephalon development
Process GO:0021542 Dentate gyrus development
Process GO:0021543 Pallium development
Process GO:0021761 Limbic system development
Process GO:0021766 Hippocampus development
Process GO:0022008 Neurogenesis
Process GO:0022603 Regulation of anatomical structure morphogenesis
Process GO:0022898 Regulation of transmembrane transporter activity
Process GO:0023051 Regulation of signaling
Process GO:0023052 Signaling
Process GO:0023056 Positive regulation of signaling
Process GO:0030030 Cell projection organization
Process GO:0030097 Hemopoiesis
Process GO:0030099 Myeloid cell differentiation
Process GO:0030154 Cell differentiation
Process GO:0030182 Neuron differentiation
Process GO:0030220 Platelet formation
Process GO:0030224 Monocyte differentiation
Process GO:0030278 Regulation of ossification
Process GO:0030279 Negative regulation of ossification
Process GO:0030318 Melanocyte differentiation
Process GO:0030334 Regulation of cell migration
Process GO:0030336 Negative regulation of cell migration
Process GO:0030500 Regulation of bone mineralization
Process GO:0030501 Positive regulation of bone mineralization
Process GO:0030855 Epithelial cell differentiation
Process GO:0030888 Regulation of B cell proliferation
Process GO:0030890 Positive regulation of B cell proliferation
Process GO:0030900 Forebrain development
Process GO:0031175 Neuron projection development
Process GO:0031323 Regulation of cellular metabolic process
Process GO:0031324 Negative regulation of cellular metabolic process
Process GO:0031325 Positive regulation of cellular metabolic process
Process GO:0031326 Regulation of cellular biosynthetic process
Process GO:0031327 Negative regulation of cellular biosynthetic process
Process GO:0031328 Positive regulation of cellular biosynthetic process
Process GO:0031347 Regulation of defense response
Process GO:0031349 Positive regulation of defense response
Process GO:0031399 Regulation of protein modification process
Process GO:0031401 Positive regulation of protein modification process
Process GO:0031667 Response to nutrient levels
Process GO:0032409 Regulation of transporter activity
Process GO:0032412 Regulation of ion transmembrane transporter activity
Process GO:0032496 Response to lipopolysaccharide
Process GO:0032501 Multicellular organismal process
Process GO:0032502 Developmental process
Process GO:0032526 Response to retinoic acid
Process GO:0032835 Glomerulus development
Process GO:0032870 Cellular response to hormone stimulus
Process GO:0032879 Regulation of localization
Process GO:0032943 Mononuclear cell proliferation
Process GO:0032944 Regulation of mononuclear cell proliferation
Process GO:0032946 Positive regulation of mononuclear cell proliferation
Process GO:0032956 Regulation of actin cytoskeleton organization
Process GO:0032970 Regulation of actin filament-based process
Process GO:0032989 Cellular component morphogenesis
Process GO:0032990 Cell part morphogenesis
Process GO:0033032 Regulation of myeloid cell apoptotic process
Process GO:0033034 Positive regulation of myeloid cell apoptotic process
Process GO:0033043 Regulation of organelle organization
Process GO:0033197 Response to vitamin E
Process GO:0033273 Response to vitamin
Process GO:0033500 Carbohydrate homeostasis
Process GO:0033554 Cellular response to stress
Process GO:0033674 Positive regulation of kinase activity
Process GO:0033993 Response to lipid
Process GO:0034284 Response to monosaccharide
Process GO:0034405 Response to fluid shear stress
Process GO:0034762 Regulation of transmembrane transport
Process GO:0034765 Regulation of ion transmembrane transport
Process GO:0035050 Embryonic heart tube development
Process GO:0035051 Cardiocyte differentiation
Process GO:0035239 Tube morphogenesis
Process GO:0035295 Tube development
Process GO:0035303 Regulation of dephosphorylation
Process GO:0035306 Positive regulation of dephosphorylation
Process GO:0035556 Intracellular signal transduction
Process GO:0035850 Epithelial cell differentiation involved in kidney development
Process GO:0035914 Skeletal muscle cell differentiation
Process GO:0035983 Response to trichostatin A
Process GO:0035984 Cellular response to trichostatin A
Process GO:0036075 Replacement ossification
Process GO:0036344 Platelet morphogenesis
Process GO:0040008 Regulation of growth
Process GO:0040011 Locomotion
Process GO:0040012 Regulation of locomotion
Process GO:0040013 Negative regulation of locomotion
Process GO:0042100 B cell proliferation
Process GO:0042113 B cell activation
Process GO:0042127 Regulation of cell population proliferation
Process GO:0042221 Response to chemical
Process GO:0042325 Regulation of phosphorylation
Process GO:0042327 Positive regulation of phosphorylation
Process GO:0042330 Taxis
Process GO:0042391 Regulation of membrane potential
Process GO:0042592 Homeostatic process
Process GO:0042593 Glucose homeostasis
Process GO:0042692 Muscle cell differentiation
Process GO:0042693 Muscle cell fate commitment
Process GO:0042981 Regulation of apoptotic process
Process GO:0043009 Chordate embryonic development
Process GO:0043065 Positive regulation of apoptotic process
Process GO:0043066 Negative regulation of apoptotic process
Process GO:0043067 Regulation of programmed cell death
Process GO:0043068 Positive regulation of programmed cell death
Process GO:0043069 Negative regulation of programmed cell death
Process GO:0043085 Positive regulation of catalytic activity
Process GO:0043170 Macromolecule metabolic process
Process GO:0043207 Response to external biotic stimulus
Process GO:0043269 Regulation of ion transport
Process GO:0043405 Regulation of MAP kinase activity
Process GO:0043406 Positive regulation of MAP kinase activity
Process GO:0043408 Regulation of MAPK cascade
Process GO:0043410 Positive regulation of MAPK cascade
Process GO:0043473 Pigmentation
Process GO:0043500 Muscle adaptation
Process GO:0043502 Regulation of muscle adaptation
Process GO:0043523 Regulation of neuron apoptotic process
Process GO:0043524 Negative regulation of neuron apoptotic process
Process GO:0043535 Regulation of blood vessel endothelial cell migration
Process GO:0043537 Negative regulation of blood vessel endothelial cell migration
Process GO:0043549 Regulation of kinase activity
Process GO:0044057 Regulation of system process
Process GO:0044087 Regulation of cellular component biogenesis
Process GO:0044093 Positive regulation of molecular function
Process GO:0044419 Biological process involved in interspecies interaction between organisms
Process GO:0045165 Cell fate commitment
Process GO:0045321 Leukocyte activation
Process GO:0045595 Regulation of cell differentiation
Process GO:0045597 Positive regulation of cell differentiation
Process GO:0045637 Regulation of myeloid cell differentiation
Process GO:0045652 Regulation of megakaryocyte differentiation
Process GO:0045661 Regulation of myoblast differentiation
Process GO:0045663 Positive regulation of myoblast differentiation
Process GO:0045664 Regulation of neuron differentiation
Process GO:0045666 Positive regulation of neuron differentiation
Process GO:0045667 Regulation of osteoblast differentiation
Process GO:0045669 Positive regulation of osteoblast differentiation
Process GO:0045778 Positive regulation of ossification
Process GO:0045859 Regulation of protein kinase activity
Process GO:0045860 Positive regulation of protein kinase activity
Process GO:0045892 Negative regulation of transcription, DNA-templated
Process GO:0045893 Positive regulation of transcription, DNA-templated
Process GO:0045927 Positive regulation of growth
Process GO:0045934 Negative regulation of nucleobase-containing compound metabolic process
Process GO:0045935 Positive regulation of nucleobase-containing compound metabolic process
Process GO:0045937 Positive regulation of phosphate metabolic process
Process GO:0045944 Positive regulation of transcription by RNA polymerase II
Process GO:0046620 Regulation of organ growth
Process GO:0046622 Positive regulation of organ growth
Process GO:0046649 Lymphocyte activation
Process GO:0046651 Lymphocyte proliferation
Process GO:0046677 Response to antibiotic
Process GO:0046928 Regulation of neurotransmitter secretion
Process GO:0048066 Developmental pigmentation
Process GO:0048167 Regulation of synaptic plasticity
Process GO:0048468 Cell development
Process GO:0048513 Animal organ development
Process GO:0048518 Positive regulation of biological process
Process GO:0048519 Negative regulation of biological process
Process GO:0048520 Positive regulation of behavior
Process GO:0048522 Positive regulation of cellular process
Process GO:0048523 Negative regulation of cellular process
Process GO:0048534 Hematopoietic or lymphoid organ development
Process GO:0048562 Embryonic organ morphogenesis
Process GO:0048568 Embryonic organ development
Process GO:0048583 Regulation of response to stimulus
Process GO:0048584 Positive regulation of response to stimulus
Process GO:0048598 Embryonic morphogenesis
Process GO:0048638 Regulation of developmental growth
Process GO:0048639 Positive regulation of developmental growth
Process GO:0048641 Regulation of skeletal muscle tissue development
Process GO:0048643 Positive regulation of skeletal muscle tissue development
Process GO:0048645 Animal organ formation
Process GO:0048646 Anatomical structure formation involved in morphogenesis
Process GO:0048660 Regulation of smooth muscle cell proliferation
Process GO:0048662 Negative regulation of smooth muscle cell proliferation
Process GO:0048666 Neuron development
Process GO:0048667 Cell morphogenesis involved in neuron differentiation
Process GO:0048699 Generation of neurons
Process GO:0048701 Embryonic cranial skeleton morphogenesis
Process GO:0048703 Embryonic viscerocranium morphogenesis
Process GO:0048704 Embryonic skeletal system morphogenesis
Process GO:0048705 Skeletal system morphogenesis
Process GO:0048706 Embryonic skeletal system development
Process GO:0048729 Tissue morphogenesis
Process GO:0048731 System development
Process GO:0048738 Cardiac muscle tissue development
Process GO:0048762 Mesenchymal cell differentiation
Process GO:0048771 Tissue remodeling
Process GO:0048812 Neuron projection morphogenesis
Process GO:0048856 Anatomical structure development
Process GO:0048858 Cell projection morphogenesis
Process GO:0048863 Stem cell differentiation
Process GO:0048869 Cellular developmental process
Process GO:0048870 Cell motility
Process GO:0048872 Homeostasis of number of cells
Process GO:0048878 Chemical homeostasis
Process GO:0050670 Regulation of lymphocyte proliferation
Process GO:0050671 Positive regulation of lymphocyte proliferation
Process GO:0050673 Epithelial cell proliferation
Process GO:0050678 Regulation of epithelial cell proliferation
Process GO:0050680 Negative regulation of epithelial cell proliferation
Process GO:0050776 Regulation of immune response
Process GO:0050778 Positive regulation of immune response
Process GO:0050789 Regulation of biological process
Process GO:0050790 Regulation of catalytic activity
Process GO:0050793 Regulation of developmental process
Process GO:0050794 Regulation of cellular process
Process GO:0050795 Regulation of behavior
Process GO:0050803 Regulation of synapse structure or activity
Process GO:0050804 Modulation of chemical synaptic transmission
Process GO:0050807 Regulation of synapse organization
Process GO:0050851 Antigen receptor-mediated signaling pathway
Process GO:0050853 B cell receptor signaling pathway
Process GO:0050864 Regulation of B cell activation
Process GO:0050865 Regulation of cell activation
Process GO:0050867 Positive regulation of cell activation
Process GO:0050871 Positive regulation of B cell activation
Process GO:0050877 Nervous system process
Process GO:0050890 Cognition
Process GO:0050896 Response to stimulus
Process GO:0050931 Pigment cell differentiation
Process GO:0051046 Regulation of secretion
Process GO:0051049 Regulation of transport
Process GO:0051094 Positive regulation of developmental process
Process GO:0051128 Regulation of cellular component organization
Process GO:0051145 Smooth muscle cell differentiation
Process GO:0051146 Striated muscle cell differentiation
Process GO:0051147 Regulation of muscle cell differentiation
Process GO:0051149 Positive regulation of muscle cell differentiation
Process GO:0051153 Regulation of striated muscle cell differentiation
Process GO:0051155 Positive regulation of striated muscle cell differentiation
Process GO:0051171 Regulation of nitrogen compound metabolic process
Process GO:0051172 Negative regulation of nitrogen compound metabolic process
Process GO:0051173 Positive regulation of nitrogen compound metabolic process
Process GO:0051174 Regulation of phosphorus metabolic process
Process GO:0051216 Cartilage development
Process GO:0051239 Regulation of multicellular organismal process
Process GO:0051240 Positive regulation of multicellular organismal process
Process GO:0051241 Negative regulation of multicellular organismal process
Process GO:0051246 Regulation of protein metabolic process
Process GO:0051247 Positive regulation of protein metabolic process
Process GO:0051249 Regulation of lymphocyte activation
Process GO:0051251 Positive regulation of lymphocyte activation
Process GO:0051252 Regulation of RNA metabolic process
Process GO:0051253 Negative regulation of RNA metabolic process
Process GO:0051254 Positive regulation of RNA metabolic process
Process GO:0051336 Regulation of hydrolase activity
Process GO:0051338 Regulation of transferase activity
Process GO:0051345 Positive regulation of hydrolase activity
Process GO:0051347 Positive regulation of transferase activity
Process GO:0051493 Regulation of cytoskeleton organization
Process GO:0051588 Regulation of neurotransmitter transport
Process GO:0051592 Response to calcium ion
Process GO:0051707 Response to other organism
Process GO:0051716 Cellular response to stimulus
Process GO:0051963 Regulation of synapse assembly
Process GO:0051966 Regulation of synaptic transmission, glutamatergic
Process GO:0055007 Cardiac muscle cell differentiation
Process GO:0055012 Ventricular cardiac muscle cell differentiation
Process GO:0055021 Regulation of cardiac muscle tissue growth
Process GO:0055023 Positive regulation of cardiac muscle tissue growth
Process GO:0055082 Cellular chemical homeostasis
Process GO:0060021 Roof of mouth development
Process GO:0060025 Regulation of synaptic activity
Process GO:0060043 Regulation of cardiac muscle cell proliferation
Process GO:0060045 Positive regulation of cardiac muscle cell proliferation
Process GO:0060078 Regulation of postsynaptic membrane potential
Process GO:0060079 Excitatory postsynaptic potential
Process GO:0060255 Regulation of macromolecule metabolic process
Process GO:0060290 Transdifferentiation
Process GO:0060297 Regulation of sarcomere organization
Process GO:0060322 Head development
Process GO:0060348 Bone development
Process GO:0060349 Bone morphogenesis
Process GO:0060350 Endochondral bone morphogenesis
Process GO:0060420 Regulation of heart growth
Process GO:0060421 Positive regulation of heart growth
Process GO:0060429 Epithelium development
Process GO:0060485 Mesenchyme development
Process GO:0060536 Cartilage morphogenesis
Process GO:0060537 Muscle tissue development
Process GO:0060538 Skeletal muscle organ development
Process GO:0060548 Negative regulation of cell death
Process GO:0060562 Epithelial tube morphogenesis
Process GO:0060914 Heart formation
Process GO:0060998 Regulation of dendritic spine development
Process GO:0061005 Cell differentiation involved in kidney development
Process GO:0061061 Muscle structure development
Process GO:0061326 Renal tubule development
Process GO:0061333 Renal tubule morphogenesis
Process GO:0061371 Determination of heart left/right asymmetry
Process GO:0061448 Connective tissue development
Process GO:0061564 Axon development
Process GO:0065007 Biological regulation
Process GO:0065008 Regulation of biological quality
Process GO:0065009 Regulation of molecular function
Process GO:0070167 Regulation of biomineral tissue development
Process GO:0070169 Positive regulation of biomineral tissue development
Process GO:0070661 Leukocyte proliferation
Process GO:0070663 Regulation of leukocyte proliferation
Process GO:0070665 Positive regulation of leukocyte proliferation
Process GO:0070848 Response to growth factor
Process GO:0070887 Cellular response to chemical stimulus
Process GO:0071107 Response to parathyroid hormone
Process GO:0071216 Cellular response to biotic stimulus
Process GO:0071219 Cellular response to molecule of bacterial origin
Process GO:0071222 Cellular response to lipopolysaccharide
Process GO:0071236 Cellular response to antibiotic
Process GO:0071241 Cellular response to inorganic substance
Process GO:0071248 Cellular response to metal ion
Process GO:0071277 Cellular response to calcium ion
Process GO:0071300 Cellular response to retinoic acid
Process GO:0071310 Cellular response to organic substance
Process GO:0071322 Cellular response to carbohydrate stimulus
Process GO:0071326 Cellular response to monosaccharide stimulus
Process GO:0071331 Cellular response to hexose stimulus
Process GO:0071333 Cellular response to glucose stimulus
Process GO:0071363 Cellular response to growth factor stimulus
Process GO:0071374 Cellular response to parathyroid hormone stimulus
Process GO:0071396 Cellular response to lipid
Process GO:0071407 Cellular response to organic cyclic compound
Process GO:0071417 Cellular response to organonitrogen compound
Process GO:0071466 Cellular response to xenobiotic stimulus
Process GO:0071495 Cellular response to endogenous stimulus
Process GO:0071498 Cellular response to fluid shear stress
Process GO:0071526 Semaphorin-plexin signaling pathway
Process GO:0071559 Response to transforming growth factor beta
Process GO:0071560 Cellular response to transforming growth factor beta stimulus
Process GO:0071704 Organic substance metabolic process
Process GO:0071840 Cellular component organization or biogenesis
Process GO:0071863 Regulation of cell proliferation in bone marrow
Process GO:0071864 Positive regulation of cell proliferation in bone marrow
Process GO:0071900 Regulation of protein serine/threonine kinase activity
Process GO:0071902 Positive regulation of protein serine/threonine kinase activity
Process GO:0072001 Renal system development
Process GO:0072006 Nephron development
Process GO:0072009 Nephron epithelium development
Process GO:0072073 Kidney epithelium development
Process GO:0072080 Nephron tubule development
Process GO:0072102 Glomerulus morphogenesis
Process GO:0072160 Nephron tubule epithelial cell differentiation
Process GO:0072359 Circulatory system development
Process GO:0080090 Regulation of primary metabolic process
Process GO:0080134 Regulation of response to stress
Process GO:0090257 Regulation of muscle system process
Process GO:0097485 Neuron projection guidance
Process GO:0097492 Sympathetic neuron axon guidance
Process GO:0098916 Anterograde trans-synaptic signaling
Process GO:0099177 Regulation of trans-synaptic signaling
Process GO:0099536 Synaptic signaling
Process GO:0099537 Trans-synaptic signaling
Process GO:0099565 Chemical synaptic transmission, postsynaptic
Process GO:0099601 Regulation of neurotransmitter receptor activity
Process GO:0110020 Regulation of actomyosin structure organization
Process GO:0110149 Regulation of biomineralization
Process GO:0110151 Positive regulation of biomineralization
Process GO:0120036 Plasma membrane bounded cell projection organization
Process GO:0120039 Plasma membrane bounded cell projection morphogenesis
Process GO:1901214 Regulation of neuron death
Process GO:1901215 Negative regulation of neuron death
Process GO:1901698 Response to nitrogen compound
Process GO:1901699 Cellular response to nitrogen compound
Process GO:1901700 Response to oxygen-containing compound
Process GO:1901701 Cellular response to oxygen-containing compound
Process GO:1901861 Regulation of muscle tissue development
Process GO:1901863 Positive regulation of muscle tissue development
Process GO:1901888 Regulation of cell junction assembly
Process GO:1902285 Semaphorin-plexin signaling pathway involved in neuron projection guidance
Process GO:1902287 Semaphorin-plexin signaling pathway involved in axon guidance
Process GO:1902531 Regulation of intracellular signal transduction
Process GO:1902533 Positive regulation of intracellular signal transduction
Process GO:1902679 Negative regulation of RNA biosynthetic process
Process GO:1902680 Positive regulation of RNA biosynthetic process
Process GO:1902903 Regulation of supramolecular fiber organization
Process GO:1903131 Mononuclear cell differentiation
Process GO:1903365 Regulation of fear response
Process GO:1903367 Positive regulation of fear response
Process GO:1903506 Regulation of nucleic acid-templated transcription
Process GO:1903507 Negative regulation of nucleic acid-templated transcription
Process GO:1903508 Positive regulation of nucleic acid-templated transcription
Process GO:1903530 Regulation of secretion by cell
Process GO:1903706 Regulation of hemopoiesis
Process GO:1904062 Regulation of cation transmembrane transport
Process GO:1904705 Regulation of vascular associated smooth muscle cell proliferation
Process GO:1904706 Negative regulation of vascular associated smooth muscle cell proliferation
Process GO:1904752 Regulation of vascular associated smooth muscle cell migration
Process GO:1904753 Negative regulation of vascular associated smooth muscle cell migration
Process GO:1904888 Cranial skeletal system development
Process GO:1905114 Cell surface receptor signaling pathway involved in cell-cell signaling
Process GO:1905207 Regulation of cardiocyte differentiation
Process GO:1905209 Positive regulation of cardiocyte differentiation
Process GO:1905562 Regulation of vascular endothelial cell proliferation
Process GO:1905563 Negative regulation of vascular endothelial cell proliferation
Process GO:2000026 Regulation of multicellular organismal development
Process GO:2000106 Regulation of leukocyte apoptotic process
Process GO:2000108 Positive regulation of leukocyte apoptotic process
Process GO:2000109 Regulation of macrophage apoptotic process
Process GO:2000111 Positive regulation of macrophage apoptotic process
Process GO:2000145 Regulation of cell motility
Process GO:2000146 Negative regulation of cell motility
Process GO:2000310 Regulation of NMDA receptor activity
Process GO:2000311 Regulation of AMPA receptor activity
Process GO:2000725 Regulation of cardiac muscle cell differentiation
Process GO:2000727 Positive regulation of cardiac muscle cell differentiation
Process GO:2000822 Regulation of behavioral fear response
Process GO:2000987 Positive regulation of behavioral fear response
Process GO:2001013 Epithelial cell proliferation involved in renal tubule morphogenesis
Process GO:2001014 Regulation of skeletal muscle cell differentiation
Process GO:2001016 Positive regulation of skeletal muscle cell differentiation
Process GO:2001141 Regulation of RNA biosynthetic process
Process GO:2001257 Regulation of cation channel activity
Component GO:0005622 Intracellular anatomical structure
Component GO:0005634 Nucleus
Component GO:0005654 Nucleoplasm
Component GO:0005737 Cytoplasm
Component GO:0005829 Cytosol
Component GO:0016528 Sarcoplasm
Component GO:0016604 Nuclear body
Component GO:0016607 Nuclear speck
Component GO:0030016 Myofibril
Component GO:0030017 Sarcomere
Component GO:0030054 Cell junction
Component GO:0031974 Membrane-enclosed lumen
Component GO:0031981 Nuclear lumen
Component GO:0032991 Protein-containing complex
Component GO:0043226 Organelle
Component GO:0043227 Membrane-bounded organelle
Component GO:0043228 Non-membrane-bounded organelle
Component GO:0043229 Intracellular organelle
Component GO:0043231 Intracellular membrane-bounded organelle
Component GO:0043232 Intracellular non-membrane-bounded organelle
Component GO:0043233 Organelle lumen
Component GO:0043292 Contractile fiber
Component GO:0045202 Synapse
Component GO:0070013 Intracellular organelle lumen
Component GO:0098794 Postsynapse
Component GO:0099080 Supramolecular complex
Component GO:0099081 Supramolecular polymer
Component GO:0099512 Supramolecular fiber
Component GO:0110165 Cellular anatomical entity
Function GO:0000217 DNA secondary structure binding
Function GO:0000976 Transcription cis-regulatory region binding
Function GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
Function GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
Function GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
Function GO:0000987 Cis-regulatory region sequence-specific DNA binding
Function GO:0001067 Transcription regulatory region nucleic acid binding
Function GO:0001216 DNA-binding transcription activator activity
Function GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
Function GO:0003676 Nucleic acid binding
Function GO:0003677 DNA binding
Function GO:0003680 Minor groove of adenine-thymine-rich DNA binding
Function GO:0003682 Chromatin binding
Function GO:0003690 Double-stranded DNA binding
Function GO:0003700 DNA-binding transcription factor activity
Function GO:0005488 Binding
Function GO:0005515 Protein binding
Function GO:0008134 Transcription factor binding
Function GO:0019899 Enzyme binding
Function GO:0019904 Protein domain specific binding
Function GO:0042826 Histone deacetylase binding
Function GO:0043565 Sequence-specific DNA binding
Function GO:0046982 Protein heterodimerization activity
Function GO:0046983 Protein dimerization activity
Function GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding
Function GO:0071837 HMG box domain binding
Function GO:0097159 Organic cyclic compound binding
Function GO:0140110 Transcription regulator activity
Function GO:0140297 DNA-binding transcription factor binding
Function GO:1901363 Heterocyclic compound binding
Function GO:1990837 Sequence-specific double-stranded DNA binding

Pathway annotation


Category Term ID Term description
RCTM RNO-1266738 Developmental Biology
RCTM RNO-525793 Myogenesis
WikiPathways WP155 Adipogenesis
WikiPathways WP358 MAPK signaling pathway
KEGG rno04010 MAPK signaling pathway
KEGG rno04022 cGMP-PKG signaling pathway
KEGG rno04371 Apelin signaling pathway
KEGG rno04921 Oxytocin signaling pathway
KEGG rno04928 Parathyroid hormone synthesis, secretion and action
KEGG rno05202 Transcriptional misregulation in cancer
KEGG rno05418 Fluid shear stress and atherosclerosis

Expression profile of Mef2c in omics data



ID GSE100499
Title Exploring acupuncture mechanism in preconditioning of IRI
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM2685201 MX1 tissue: Myocardium gender: male 10.696095
GSM2685202 MX2 tissue: Myocardium gender: female 10.62367
GSM2685203 MX3 tissue: Myocardium gender: female 10.783744
GSM2685204 MX4 tissue: Myocardium gender: male 11.06103
GSM2685205 DZ1 tissue: Myocardium gender: male 11.090402
GSM2685206 DZ2 tissue: Myocardium gender: male 11.251188
GSM2685207 DZ3 tissue: Myocardium gender: female 11.092463
GSM2685208 DZ4 tissue: Myocardium gender: female 10.970137
GSM2685209 JJ1 tissue: Myocardium gender: male 10.743188
GSM2685210 JJ2 tissue: Myocardium gender: female 10.928397
GSM2685211 JJ3 tissue: Myocardium gender: female 11.047695
GSM2685212 JJ4 tissue: Myocardium gender: male 11.003157
GSM2685213 NG1 tissue: Myocardium gender: male 10.769562
GSM2685214 NG2 tissue: Myocardium gender: female 11.065304
GSM2685215 NG3 tissue: Myocardium gender: male 10.898088
GSM2685216 NG4 tissue: Myocardium gender: female 10.885638
GSM2685217 YL1 tissue: Myocardium gender: male 10.911165
GSM2685218 YL2 tissue: Myocardium gender: male 10.892843
GSM2685219 YL3 tissue: Myocardium gender: female 10.972378
GSM2685220 YL4 tissue: Myocardium gender: female 10.885638
GSM2685221 QC1 tissue: Myocardium gender: male 11.067155
GSM2685222 QC2 tissue: Myocardium gender: male 10.711282
GSM2685223 QC3 tissue: Myocardium gender: female 10.403049
GSM2685224 QC4 tissue: Myocardium gender: female 10.5210905

ID GSE136833
Title Effects of lidocaine on the expression of rat spinal cord
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM4058984 Control_1 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 5.583956851
GSM4058985 Control_2 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 5.710759149
GSM4058986 Control_3 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 5.594841826
GSM4058987 Lidocaine_1 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 5.812129511
GSM4058988 Lidocaine_2 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 5.572219175
GSM4058989 Lidocaine_3 strain: Sprague-Dawley tissue: Lumbar segment of spinal cord 6.037830281

ID GSE157924
Title Regulation of acupuncture on genes in brain stem
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM4780973 Rattus_JSSZ(Sham) tissue: Rattus brainstem of modeling treatment: Sham 10.3113039605
GSM4780974 Rattus_JXZ(Hand Acu) tissue: Rattus brainstem of modeling treatment: Hand Acu 10.68159317
GSM4780975 Rattus_MXZ(TBI) tissue: Rattus brainstem of modeling treatment: TBI 9.9472766775

ID GSE1779
Title Effect of Isoflurane and LTM on basolateral amygdala
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM30790 baseline control 01 male, 275-300g 3742.25
GSM30791 baseline control 02 male, 275-300g 1025.15
GSM30792 baseline control 03 male, 275-300g 1242.45
GSM30793 baseline control 04 male, 275-300g 3025.4
GSM30794 baseline control 05 male, 275-300g 2213.8
GSM30795 baseline control 06 male, 275-300g 2400.95
GSM30796 baseline control 07 male, 275-300g 1291.8
GSM30797 baseline control 08 male, 275-300g 1439.6999999999998
GSM30798 baseline control 09 male, 275-300g 1773.8
GSM30799 pain 01 1888.5500000000002
GSM30800 pain 02 1746.3000000000002
GSM30801 pain 03 1453.9499999999998
GSM30802 pain 04 2722.8500000000004
GSM30803 pain 05 1873.8
GSM30804 FC 01 2118.9
GSM30805 FC 02 1662.75
GSM30806 FC 03 3030.55
GSM30807 FC 04 1439.85
GSM30808 FC 05 1999.0
GSM30809 IFC 01 1731.0
GSM30810 IFC 02 2454.25
GSM30811 IFC 03 2611.05
GSM30812 IFC 04 3047.05
GSM30813 IFC 05 2481.35
GSM99800 isoflurane 01 male, 275-300g 2348.1499999999996
GSM99801 isoflurane 02 male, 275-300g 2880.55
GSM99802 isoflurane 03 male, 275-300g 1818.7
GSM99803 isoflurane 04 male, 275-300g 2182.45
GSM99804 isoflurane 05 male, 275-300g 3160.5

ID GSE190472
Title Study on VEGF regulation mechanism of acupuncture improving endometrial receptivity in IVF-ET
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM5724271 model 21 Sex: female tissue: Uterine tissue condition: model 53.9426
GSM5724272 model 22 Sex: female tissue: Uterine tissue condition: model 86.2478
GSM5724273 model 23 Sex: female tissue: Uterine tissue condition: model 65.8983
GSM5724274 treatment31 Sex: female tissue: Uterine tissue condition: treatment 50.473600000000005
GSM5724275 treatment32 Sex: female tissue: Uterine tissue condition: treatment 26.34095
GSM5724276 treatment33 Sex: female tissue: Uterine tissue condition: treatment 45.32835
GSM5724277 control 41 Sex: female tissue: Uterine tissue condition: control 32.66915
GSM5724278 control 42 Sex: female tissue: Uterine tissue condition: control 43.1822
GSM5724279 control 43 Sex: female tissue: Uterine tissue condition: control 66.83065

ID GSE205202
Title Hepatic responses of mice and rats to equivalent acetaminophen (APAP) insult [rat]
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM6208507 Rat_Baseline_0h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: Untreated hours after treatment: 0 5.688603
GSM6208508 Rat_Baseline_0h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: Untreated hours after treatment: 0 5.467016
GSM6208509 Rat_Baseline_0h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: Untreated hours after treatment: 0 5.592036
GSM6208510 Rat_Baseline_0h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: Untreated hours after treatment: 0 5.551114
GSM6208511 Rat_Baseline_0h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: Untreated hours after treatment: 0 5.757484
GSM6208512 Rat_Vehicle_03h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 3 5.706859
GSM6208513 Rat_Vehicle_03h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 3 5.623615
GSM6208514 Rat_Vehicle_03h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 3 5.666978
GSM6208515 Rat_Vehicle_03h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 3 5.685168
GSM6208516 Rat_Vehicle_03h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 3 5.534362
GSM6208517 Rat_Vehicle_06h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 6 5.608539
GSM6208518 Rat_Vehicle_06h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 6 5.824584
GSM6208519 Rat_Vehicle_06h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 6 5.793106
GSM6208520 Rat_Vehicle_06h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 6 5.801579
GSM6208521 Rat_Vehicle_06h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 6 5.677513
GSM6208522 Rat_Vehicle_09h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 9 5.575625
GSM6208523 Rat_Vehicle_09h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 9 5.820011
GSM6208524 Rat_Vehicle_09h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 9 5.72518
GSM6208525 Rat_Vehicle_09h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 9 5.796902
GSM6208526 Rat_Vehicle_09h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 9 5.893195
GSM6208527 Rat_Vehicle_24h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 24 5.29833
GSM6208528 Rat_Vehicle_24h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 24 5.890778
GSM6208529 Rat_Vehicle_24h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 24 5.665028
GSM6208530 Rat_Vehicle_24h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 24 5.824239
GSM6208531 Rat_Vehicle_24h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: Vehicle (1% [w/v] hydroxyethylcellulose, o.g.) hours after treatment: 24 5.331405
GSM6208532 Rat_APAP_03h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 3 5.68217
GSM6208533 Rat_APAP_03h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 3 5.53049
GSM6208534 Rat_APAP_03h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 3 5.236389
GSM6208535 Rat_APAP_03h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 3 5.316818
GSM6208536 Rat_APAP_03h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 3 5.573738
GSM6208537 Rat_APAP_06h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 6 5.322801
GSM6208538 Rat_APAP_06h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 6 5.478791
GSM6208539 Rat_APAP_06h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 6 5.271702
GSM6208540 Rat_APAP_06h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 6 5.618503
GSM6208541 Rat_APAP_06h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 6 5.451995
GSM6208542 Rat_APAP_09h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 9 5.523987
GSM6208543 Rat_APAP_09h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 9 5.308203
GSM6208544 Rat_APAP_09h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 9 5.472286
GSM6208545 Rat_APAP_09h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 9 5.503928
GSM6208546 Rat_APAP_09h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 9 5.457133
GSM6208547 Rat_APAP_24h_1 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 24 5.566051
GSM6208548 Rat_APAP_24h_2 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 24 5.261436
GSM6208549 Rat_APAP_24h_3 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 24 5.418613
GSM6208550 Rat_APAP_24h_4 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 24 5.378021
GSM6208551 Rat_APAP_24h_5 tissue: liver strain: Sprague-Dawley Sex: male treatment: 1000 mg/kg acetamnophen (o.g.) hours after treatment: 24 5.539701

ID GSE48025
Title Affymetrix Chip Data of the Transcriptome of the Rheumatoid Arthritis Rat Model Treated with Acupuncture (Affymetrix, mRNA, batch1)
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM1165929 RAT_NORA_T0_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats before therapy 8.608140474
GSM1165930 RAT_NORA_T0_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats before therapy 8.799457005499999
GSM1165931 RAT_RA_T0_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats before therapy 7.820375283
GSM1165932 RAT_RA_T0_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats before therapy 7.9725870615
GSM1165933 RAT_NORA_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 1 hour after therapy 8.0074712815
GSM1165934 RAT_NORA_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 1 hour after therapy 8.025652793999999
GSM1165935 RAT_AP_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour acupuncture therapy 8.367697655499999
GSM1165936 RAT_AP_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour acupuncture therapy 8.0793620525
GSM1165937 RAT_MTX_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour MTX therapy 7.930944054
GSM1165938 RAT_MTX_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour MTX therapy 8.0860877265
GSM1165939 RAT_ANE_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour ANE therapy 7.31753705
GSM1165940 RAT_ANE_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour ANE therapy 7.281139289
GSM1165941 RAT_PLA_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour placebo therapy 7.5870267285
GSM1165942 RAT_PLA_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour placebo therapy 7.658381566999999
GSM1165943 RAT_NORA_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 34 days after therapy 7.365070226
GSM1165944 RAT_NORA_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 34 days after therapy 7.1461537995
GSM1165945 RAT_AP_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days acupuncture therapy 8.905142573500001
GSM1165946 RAT_AP_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days acupuncture therapy 7.115615483499999
GSM1165947 RAT_MTX_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days MTX therapy 7.666297288000001
GSM1165948 RAT_MTX_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days MTX therapy 7.0913255495000005
GSM1165949 RAT_ANE_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days ANE therapy 7.9443105855
GSM1165950 RAT_ANE_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days ANE therapy 8.131835564500001
GSM1165951 RAT_PLA_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days placebo therapy 7.344844082
GSM1165952 RAT_PLA_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days placebo therapy 7.1826872295

ID GSE58456
Title Affymetrix Chip Data of the Transcriptome of the Rheumatoid Arthritis Rat Model Treated with Acupuncture (Affymetrix, mRNA, batch 2)
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM1693996 Peripheral blood mononuclear cells from NORA before therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats before therapy 468.6868545
GSM1693997 Peripheral blood mononuclear cells from NORA before therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats before therapy 1206.73409
GSM1693998 Peripheral blood mononuclear cells from NORA before therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats before therapy 994.7900443
GSM1693999 Peripheral blood mononuclear cells from RA before therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats before therapy 1100.20067415
GSM1694000 Peripheral blood mononuclear cells from RA before therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats before therapy 715.3019532999999
GSM1694001 Peripheral blood mononuclear cells from HAP after 34 days acupuncture therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats after 34 days acupuncture therapy 1240.8535418000001
GSM1694002 Peripheral blood mononuclear cells from HAP after 34 days acupuncture therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats after 34 days acupuncture therapy 736.0590683
GSM1694003 Peripheral blood mononuclear cells from HAP after 34 days acupuncture therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats after 34 days acupuncture therapy 1368.3148015
GSM1694004 Peripheral blood mononuclear cells from AP after 34 days acupuncture therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days acupuncture therapy 1681.687648
GSM1694005 Peripheral blood mononuclear cells from AP after 34 days acupuncture therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days acupuncture therapy 1139.5331124
GSM1694006 Peripheral blood mononuclear cells from AP after 34 days acupuncture therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days acupuncture therapy 986.92860935
GSM1694007 Peripheral blood mononuclear cells from MTXAP after 34 days MTX&acupuncture therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days methotrexate & acupuncture therapy 472.51770045
GSM1694008 Peripheral blood mononuclear cells from MTXAP after 34 days MTX&acupuncture therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days methotrexate & acupuncture therapy 786.3745554500001
GSM1694009 Peripheral blood mononuclear cells from MTXAP after 34 days MTX&acupuncture therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days methotrexate & acupuncture therapy 930.65297715

ID GSE58460
Title Rheumatoid Arthritis Rat Model Treated with Acupuncture
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM1165929 RAT_NORA_T0_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats before therapy 8.608140474
GSM1165930 RAT_NORA_T0_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats before therapy 8.799457005499999
GSM1165931 RAT_RA_T0_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats before therapy 7.820375283
GSM1165932 RAT_RA_T0_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats before therapy 7.9725870615
GSM1165933 RAT_NORA_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 1 hour after therapy 8.0074712815
GSM1165934 RAT_NORA_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 1 hour after therapy 8.025652793999999
GSM1165935 RAT_AP_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour acupuncture therapy 8.367697655499999
GSM1165936 RAT_AP_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour acupuncture therapy 8.0793620525
GSM1165937 RAT_MTX_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour MTX therapy 7.930944054
GSM1165938 RAT_MTX_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour MTX therapy 8.0860877265
GSM1165939 RAT_ANE_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour ANE therapy 7.31753705
GSM1165940 RAT_ANE_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour ANE therapy 7.281139289
GSM1165941 RAT_PLA_1h_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour placebo therapy 7.5870267285
GSM1165942 RAT_PLA_1h_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 1 hour placebo therapy 7.658381566999999
GSM1165943 RAT_NORA_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 34 days after therapy 7.365070226
GSM1165944 RAT_NORA_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: healthy rats at 34 days after therapy 7.1461537995
GSM1165945 RAT_AP_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days acupuncture therapy 8.905142573500001
GSM1165946 RAT_AP_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days acupuncture therapy 7.115615483499999
GSM1165947 RAT_MTX_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days MTX therapy 7.666297288000001
GSM1165948 RAT_MTX_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days MTX therapy 7.0913255495000005
GSM1165949 RAT_ANE_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days ANE therapy 7.9443105855
GSM1165950 RAT_ANE_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days ANE therapy 8.131835564500001
GSM1165951 RAT_PLA_34d_1 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days placebo therapy 7.344844082
GSM1165952 RAT_PLA_34d_2 gender: Female tissue: RAT Peripheral blood mononuclear cells strain: Wistar rat subject group: RA rats after 34 days placebo therapy 7.1826872295
GSM1412003 RAT_NORA_T0_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412004 RAT_NORA_T0_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412005 RAT_RA_T0_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412006 RAT_RA_T0_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412007 RAT_NORA_1h_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412008 RAT_NORA_1h_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412009 RAT_AP_1h_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412010 RAT_AP_1h_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412011 RAT_MTX_1h_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412012 RAT_MTX_1h_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412013 RAT_ANE_1h_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412014 RAT_ANE_1h_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412015 RAT_PLA_1h_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412016 RAT_PLA_1h_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412017 RAT_NORA_34d_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412018 RAT_NORA_34d_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412019 RAT_AP_34d_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412020 RAT_AP_34d_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412021 RAT_MTX_34d_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412022 RAT_MTX_34d_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412023 RAT_ANE_34d_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412024 RAT_ANE_34d_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412025 RAT_PLA_34d_1 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412026 RAT_PLA_34d_2 strain: Wistar gender: Female tissue: RAT Peripheral blood mononuclear cells
GSM1412027 RAT_RA_T0_1 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412028 RAT_RA_T0_2 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412029 RAT_AP_1h_1 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412030 RAT_AP_1h_2 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412031 RAT_PLA_1h_1 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412032 RAT_PLA_1h_2 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412033 RAT_AP_34d_1 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412034 RAT_AP_34d_2 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412035 RAT_PLA_34d_1 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1412036 RAT_PLA_34d_2 strain: Wistar gender: Female tissue: RAT Sub-epidermidis muscle tissue
GSM1693996 Peripheral blood mononuclear cells from NORA before therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats before therap 468.6868545
GSM1693997 Peripheral blood mononuclear cells from NORA before therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats before therapy 1206.73409
GSM1693998 Peripheral blood mononuclear cells from NORA before therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats before therapy 994.7900443
GSM1693999 Peripheral blood mononuclear cells from RA before therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats before therapy 1100.20067415
GSM1694000 Peripheral blood mononuclear cells from RA before therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats before therapy 715.3019532999999
GSM1694001 Peripheral blood mononuclear cells from HAP after 34 days acupuncture therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats after 34 days acupuncture therapy 1240.8535418000001
GSM1694002 Peripheral blood mononuclear cells from HAP after 34 days acupuncture therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats after 34 days acupuncture therap 736.0590683
GSM1694003 Peripheral blood mononuclear cells from HAP after 34 days acupuncture therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: healthy rats after 34 days acupuncture therapy 1368.3148015
GSM1694004 Peripheral blood mononuclear cells from AP after 34 days acupuncture therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days acupuncture therapy 1681.687648
GSM1694005 Peripheral blood mononuclear cells from AP after 34 days acupuncture therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days acupuncture therapy 1139.5331124
GSM1694006 Peripheral blood mononuclear cells from AP after 34 days acupuncture therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days acupuncture therapy 986.92860935
GSM1694007 Peripheral blood mononuclear cells from MTXAP after 34 days MTX&acupuncture therapy, replicate 1 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days methotrexate & acupuncture therapy 472.51770045
GSM1694008 Peripheral blood mononuclear cells from MTXAP after 34 days MTX&acupuncture therapy, replicate 2 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days methotrexate & acupuncture therapy 786.3745554500001
GSM1694009 Peripheral blood mononuclear cells from MTXAP after 34 days MTX&acupuncture therapy, replicate 3 strain/background: Wistar gender: female cell type: peripheral blood mononuclear cells subject group: rheumatoid arthritis rats after 34 days methotrexate & acupuncture therapy 930.65297715

ID GSE8911
Title Skeletal muscle after fine needle stimulation
Organism Rattus norvegicus
GSM Sample info Characteristics Value
GSM225891 Skeletal muscle sample from fine needle-stimulated hindlimb Strain: Lewis, Gender: Male, Body Weight: 275g, Tissue: Skeletal muscle sample from fine nnedle-stimulated hindlimb 2366.585
GSM225892 Skeletal muscle sample from control hindlimb Strain: Lewis, Gender: Male, Body weight: 275g, Tissue: skeletal muscle sample from non fine needle-stimulated hindlimb 2491.66