- The advantages of acupuncture anesthesia in clinical practice
In clinical practice, acupuncture anesthesia presents a multitude of advantages, pivotal among these being Body System Protection. This technique supports the body's natural defenses, reducing the physiological stress often associated with surgical procedures. By modulating the body's response to pain, acupuncture anesthesia allows for a lower Dosage of Medication, significantly reducing the potential for drug-related side effects. Furthermore, this approach plays a crucial role in Emotion Regulation, helping patients maintain a calm and stable emotional state, which is essential for a positive surgical outcome. The impact of acupuncture on the nervous system not only aids in Pain Relief but also promotes Enhanced Recovery After Surgery. Patients tend to experience faster recuperation times, attributed to the holistic nature of this method. Additionally, acupuncture anesthesia is associated with a Lower Incidence of Side Effects compared to conventional anesthetics. Its ability to modulate and balance the body's responses makes it an invaluable tool in the realm of modern medicine, offering a safer, more patient-centered approach to pain management and recovery.
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Modulation
- Immunity
- Acupuncture anesthesia may enhance the body's immune response, reducing the risk of postoperative infections.
- Blood Flow
- Acupuncture anesthesia can optimize blood flow to tissues, aiding in wound healing and tissue recovery.
- Endocrinology
- Acupuncture anesthesia can influence endocrine function, helping maintain hormonal balance during surgery.
- Circulation
- Acupuncture anesthesia supports overall circulatory health, ensuring adequate oxygen and nutrient delivery to tissues.
- Microcirculation
- Acupuncture anesthesia positively affects microcirculation, benefiting tissue perfusion and healing.
- Blood Pressure
- Acupuncture anesthesia can help stabilize blood pressure, reducing perioperative hypertension risks.
- Heart Rate
- Acupuncture anesthesia can regulate heart rate, promoting cardiovascular stability during surgery.
- Hemodynamics
- Acupuncture anesthesia optimizes hemodynamic parameters, contributing to surgical safety.
- Bleeding
- Acupuncture anesthesia may reduce intraoperative bleeding, enhancing surgical outcomes.
- Skin Temperature
- Acupuncture anesthesia can help maintain stable skin temperature during surgery, preventing hypothermia.
Acupuncture anesthesia for Modulation-Circulation
| PMID | Evidence | Source | Keyword | Type |
|---|---|---|---|---|
| 1581663 | It appears that acupuncture not only provides long-term analgesia but also increases circulation to the affected areas and decreases inflammation. | Probl Vet Med. 1992 Mar;4(1):88-97. | Circulation | Review |
| 17206916 | Bioengineering assessment of acupuncture, part 2: monitoring of microcirculation. | Crit Rev Biomed Eng. 2006;34(4):273-94. doi: 10.1615/critrevbiomedeng.v34.i4.10. | Microcirculation | Review |
| 17206916 | In the second part of the review article, monitoring of microcirculation during acupuncture is described. | Crit Rev Biomed Eng. 2006;34(4):273-94. doi: 10.1615/critrevbiomedeng.v34.i4.10. | Microcirculation | Review |
| 17206916 | Using these types of biomedical equipment, it is possible to quantify and objectify peripheral changes in microcirculation during different methods of acupuncture stimulation (manual needle acupuncture and laserneedle acupuncture). | Crit Rev Biomed Eng. 2006;34(4):273-94. doi: 10.1615/critrevbiomedeng.v34.i4.10. | Microcirculation | Review |
| 17907396 | In the present paper, the authors review the current development of studies on mechanisms of acupuncture treatment of acute ischemic cerebral apoplexy from (1) blood rheology, (2) cerebral microcirculation, 3) metabolism of cerebral tissue, (4) cerebral electrical activity, (5) free radicals and lipid peroxidation reaction, (6) excitatory aminoacid, (7) calcium overload, (8) nitrogen monoxidum, and (9) cerebral apoptosis. | Zhen Ci Yan Jiu. 2007 Aug;32(4):285-8. | Microcirculation | Review |
| 20359125 | Therefore, we vigorously review the relations between SSR and acupuncture-related analgesia so that we can develop a targeted pain therapy where in certain areas of the body undergo site-specific somatic stimulation, which in turn, can adjust the impaired regional blood circulation. | Chin J Physiol. 2009 Nov 30;52(5 Suppl):345-57. doi: 10.4077/cjp.2009.amk043. | Circulation | Review |
| 20633480 | Bonghan circulatory system as an extension of acupuncture meridians. | J Acupunct Meridian Stud. 2009 Jun;2(2):93-106. doi: 10.1016/S2005-2901(09)60041-8. | Circulation | Review |
| 20633480 | The Bonghan system is a newly-discovered circulatory system, which corresponds to classical acupuncture meridians and was discovered in the early 1960s by Bonghan Kim. | J Acupunct Meridian Stud. 2009 Jun;2(2):93-106. doi: 10.1016/S2005-2901(09)60041-8. | Circulation | Review |
| 21090338 | In the present paper, the authors review recent development of experimental researches on the mechanism underlying acupuncture-induced improvement of migraine from: 1) inhibiting neurogenic inflammation, 2) improving cerebro-microcirculation, and 3) regulating vasoactive substances. | Zhen Ci Yan Jiu. 2010 Aug;35(4):315-8. | Microcirculation | Review |
| 22500707 | High-tech acupuncture made in Austria--cerebral circulation. | Zhong Xi Yi Jie He Xue Bao. 2012 Apr;10(4):362-8. doi: 10.3736/jcim20120402. | Circulation | Review |
| 22500707 | Within this review article, a short summary concerning high-tech acupuncture and cerebral circulation, and transcranial Doppler (TCD) sonography is presented. | Zhong Xi Yi Jie He Xue Bao. 2012 Apr;10(4):362-8. doi: 10.3736/jcim20120402. | Circulation | Review |
| 23917395 | EA studies, particularly with low frequency stimulation, are more likely to support the role of endogenous opioid mechanisms than manual acupuncture studies, and opioid release is more likely in the central nervous system than the circulation. | Acupunct Med. 2013 Dec;31(4):409-15. doi: 10.1136/acupmed-2013-010324. Epub 2013 Aug 5. | Circulation | Review |
| 24215922 | Series of clinical trials have shown that acupuncture primarily regulates the release of neurochemicals, hemorheology, cerebral microcirculation, metabolism, neuronal activity, and the function of specific brain region. | Int Rev Neurobiol. 2013;111:159-79. doi: 10.1016/B978-0-12-411545-3.00008-0. | Microcirculation | Review |
| 25219132 | In the present paper, the authors introduce 1) progress of researches on the pathogenesis of hypertension from cellular immune and body fluid immune (multiple immuno-humoral factors); 2) effects of acupuncture intervention on natural killer cell activity, exercise-induced immunosuppression, circulating inflammatory factor levels and balance of cytokines; 3) blood-pressure reduction effect of acupuncture intervention by lowering circulating TNF-alpha, IL-6, matrix metalloproteinases-9, angiotensin convertase and endothelin levels, and up-regulating serum opioid peptide content, etc. | Zhen Ci Yan Jiu. 2014 Aug;39(4):333-6. | Immunity Blood Pressure Circulation | Review |
| 2568074 | Beneficial effects of external Qi Gong treatment given by a Qi Gong practitioner 1 to 3 times for 10-20 seconds each (although most Qi Gong masters take 3-20 minutes per treatment) often resulted in improvement of circulation and lowering of high blood pressure, as well as relaxation of spastic muscles, relief of pain, and enhanced general well-being, all of which resemble acupuncture effects. | Acupunct Electrother Res. 1989;14(1):61-89. doi: 10.3727/036012989816358506. | Pain Relief Blood Pressure Circulation | Review |
| 25854040 | Development on research of acupuncture effects on microcirculation. | Zhongguo Zhen Jiu. 2015 Feb;35(2):203-8. | Microcirculation | Review |
| 25854040 | The Chinese and English published literature regarding the effects of acupuncture on microcirculation in recent years were analyzed, and it was found out that the theory of TCM meridian had subtle connection with microcirculation on structure and function, which could provide a possible breakthrough for the research of meridian essence. | Zhongguo Zhen Jiu. 2015 Feb;35(2):203-8. | Microcirculation | Review |
| 25854040 | Acupuncture, through multiple links, multiple paths and multiple levels, could regulate microcirculation under physiological or pathological condition, which was a bidirectional benign adjustment function, and reflected the characteristic of acupoint specificity. | Zhongguo Zhen Jiu. 2015 Feb;35(2):203-8. | Microcirculation | Review |
| 27141629 | Results indicate that scalp acupuncture intervention can 1) improve cerebral blood circulation to promote regional energy metabolism, 2) up-regulate expression of glial cell-line derived neurotrophic factor (GDNF), etc., possibly promoting proliferation and differentiation of neural stem cells in the focal cerebral cortex and hippocampus, 3) reduce contents of excitatory amino acid and increase level of gamma-aminobutyric acid (GABA) to lower neurogenic toxicity, and relieve cerebral injury, 4) ease cerebral vascular immunoinflammatory reactions, 5) regulate blood lipid metabolism to resist cerebral free radical damage, and 6) inhibit cerebral cortical apoptosis. | Zhen Ci Yan Jiu. 2016 Feb;41(1):87-9, 93. | Immunity Toxic Side Effects Circulation | Review |
| 27535246 | These results suggested that the change in blood circulation of the tendon during acupuncture with up-and-down manipulation was caused by axon reflex, and increase in blood flow in the tendons after the needle removal might be caused through the central nervous system. | Adv Exp Med Biol. 2016;920:27-33. doi: 10.1007/978-3-319-33943-6_3. | Circulation Blood Flow | Review |
| 27535246 | Therefore, these phenomena would be related to the changes in blood circulation of tendons due to heating and acupuncture treatments. | Adv Exp Med Biol. 2016;920:27-33. doi: 10.1007/978-3-319-33943-6_3. | Circulation | Review |
| 2895568 | Basic electrical parameters for safe and effective electro-therapeutics [electro-acupuncture, TES, TENMS (or TEMS), TENS and electro-magnetic field stimulation with or without drug field] for pain, neuromuscular skeletal problems, and circulatory disturbances. | Acupunct Electrother Res. 1987;12(3-4):201-25. doi: 10.3727/036012987816358788. | Circulation | Review |
| 29071952 | In this way, the mechanism of cytokines in multi-targets (such as local joints, peripheral blood circulation, central nervous system) involving the effects of acupuncture in improving RA will be known more. | Zhen Ci Yan Jiu. 2016 Oct 25;41(5):469-73. | Circulation | Review |
| 29071953 | We found that:1) in the past 10 years, the amount of fMRI studies on acupuncture is growing; 2) most of these studies (183) are conducted in healthy subjects, and fewer studies (44) conducted in patients with problems of neurology, psychonosology, gastroenterology, circulation system, pediatrics, myopia and dermatology, or with pain; 3)a larger population of studies are designed to reveal the specificity of responses of acupuncture point stimulation, and fewer focus on analyzing the regularities of acupuncture points combination. | Zhen Ci Yan Jiu. 2016 Oct 25;41(5):474-8. | Circulation | Review |
| 33371816 | The number of clinical publications concerning acupuncture-treated neurological diseases, endocrine and metabolic diseases, circulatory diseases, respiratory diseases, etc. | Am J Chin Med. 2021;49(1):1-23. doi: 10.1142/S0192415X21500014. Epub 2020 Dec 26. | Endocrinology Circulation | Review |
| 8073239 | To establish responders and non-responders, lung function tests and measurement of microcirculation and skin temperature are carried out before and after acupuncture treatment. | Schweiz Med Wochenschr Suppl. 1994;62:39-48. | Microcirculation Skin Temperature | Review |
| 16824230 | Three studies referred to local effects of acupuncture on tissues or nerves or mechanical effects on connective tissue; other studies secondarily referred to changes in circulation, especially vasodilation, or effects on immune function. | BMC Complement Altern Med. 2006 Jul 7;6:25. doi: 10.1186/1472-6882-6-25. | Immunity Circulation | Review |
| 16824230 | However, there were positive findings in 17 of 18 studies (94%) whose outcome of interest measured specific physiologic changes (brain blood flow using fMRI imaging, muscle blood flow, morphologic changes in sperm structure, association of acupuncture response to genotype, effect on leukocyte circulation, heart rate or heart rate variability, blood pressure, sweat rate, tissue impedance, sensations of skin piercing, post-menopausal vasomotor symptoms or ultrasound imaging of tissue morphology.) | BMC Complement Altern Med. 2006 Jul 7;6:25. doi: 10.1186/1472-6882-6-25. | Heart Rate Blood Pressure Circulation Blood Flow | Review |
| 23728665 | indented the skin with a blunt probe and placed over the area a small circular plaster rigged with an acupuncture needle that stuck out; they stated that preliminary trials showed volunteers could not tell the difference. | Cochrane Database Syst Rev. 2013 May 31;2013(5):CD007070. doi: 10.1002/14651858.CD007070.pub2. | Circulation | Review |
| 24073009 | Both circulating and central levels of β-endorphin have been shown to be modulated by acupuncture. | Evid Based Complement Alternat Med. 2013;2013:762615. doi: 10.1155/2013/762615. Epub 2013 Sep 2. | Circulation | Review |
| 24073009 | This is also supported in our recent experimental study where electrical stimulation of the acupuncture needles affected the expression of opioid receptors μ and κ in rat hypothalamus, together with improved cyclicity and reduction of circulating testosterone levels. | Evid Based Complement Alternat Med. 2013;2013:762615. doi: 10.1155/2013/762615. Epub 2013 Sep 2. | Circulation | Review |
| 24073009 | In addition, we found reduced circulating levels of inhibin B after acupuncture, without changes in AMH which was in line with a previous study. | Evid Based Complement Alternat Med. 2013;2013:762615. doi: 10.1155/2013/762615. Epub 2013 Sep 2. | Circulation | Review |
| 24073009 | The major effect accompanying the higher ovulation frequency and reduced circulating inhibin B levels in the acupuncture group was the general decrease in circulating sex steroids, androgen precursors, and glucuronidated androgen metabolites after treatment, pointing towards an effect at ovarian and adrenal levels. | Evid Based Complement Alternat Med. 2013;2013:762615. doi: 10.1155/2013/762615. Epub 2013 Sep 2. | Circulation | Review |
| 24278807 | Regular exercise helps the blood circulation and keeps muscles active, and this also accelerates the results from ongoing acupuncture treatments. | Glob Adv Health Med. 2012 Mar;1(1):102-21. doi: 10.7453/gahmj.2012.1.1.017. | Circulation | Review |
| 24278807 | It helps the blood circulation and keeps muscles active, accelerating the results from ongoing acupuncture treatments. | Glob Adv Health Med. 2012 Mar;1(1):102-21. doi: 10.7453/gahmj.2012.1.1.017. | Circulation | Review |
| 24648850 | The needles produce positive stimulation at local acupuncture points, which can promote the local blood circulation, elevate the metabolic ability, and ameliorate the pathology while promoting inflammation absorption. | Evid Based Complement Alternat Med. 2014;2014:658624. doi: 10.1155/2014/658624. Epub 2014 Feb 4. | Circulation | Review |
| 24809037 | Moreover, acupuncture have been shown to increase glucose uptake and microcirculation. | Transl Med UniSa. 2014 Apr 24;9:56-65. eCollection 2014 Apr. | Microcirculation | Review |
| 24809037 | Furthermore, acupuncture in rats normalizes estrous cyclicity, improves ovarian morphology, reduces circulating concentrations of inhibin B and increases progesterone levels. | Transl Med UniSa. 2014 Apr 24;9:56-65. eCollection 2014 Apr. | Circulation | Review |
| 25614752 | Accordingly, it is believed in TCM that acupuncture achieves its efficacy like pain relief via regulation of qi and blood and promotion of their circulation along the meridians. | Evid Based Complement Alternat Med. 2014;2014:609594. doi: 10.1155/2014/609594. Epub 2014 Dec 29. | Pain Relief Circulation | Review |
| 26124961 | Acupuncture may improve the activities and speed of the rod and cone cells of retina, enhance the neural networks and biological activity of the retina cells, and improve the inner circulation, the metabolic activities of retinal epithelium-photoreceptors complexes, and the damages to visual function. | J Ophthalmol. 2015;2015:421269. doi: 10.1155/2015/421269. Epub 2015 Jun 1. | Circulation | Review |
| 26221180 | The Effects of Acupuncture on Cerebral and Muscular Microcirculation: A Systematic Review of Near-Infrared Spectroscopy Studies | Evid Based Complement Alternat Med. 2015;2015:839470. doi: 10.1155/2015/839470. Epub 2015 Jun 11. | Microcirculation | Review |
| 26221180 | We review the literature investigating the effect of acupuncture on muscular and/or cerebral microcirculation. | Evid Based Complement Alternat Med. 2015;2015:839470. doi: 10.1155/2015/839470. Epub 2015 Jun 11. | Microcirculation | Review |
| 27403201 | Studies demonstrating any type of microcirculation response to manual acupuncture in healthy subjects and patients were included. | Evid Based Complement Alternat Med. 2016;2016:9874207. doi: 10.1155/2016/9874207. Epub 2016 Jun 14. | Microcirculation | Review |
| 27403201 | Of the seven studies in healthy subjects, four reported significant increases in blood flow following acupuncture compared with control, whereas one other study observed reductions in microcirculation immediately after acupuncture needling. | Evid Based Complement Alternat Med. 2016;2016:9874207. doi: 10.1155/2016/9874207. Epub 2016 Jun 14. | Microcirculation Blood Flow | Review |
| 27403201 | Microcirculation is affected by the autonomic nervous system (ANS) and is regarded as a useful method with which to evaluate the peripheral effects of acupuncture. | Evid Based Complement Alternat Med. 2016;2016:9874207. doi: 10.1155/2016/9874207. Epub 2016 Jun 14. | Microcirculation | Review |
| 27403201 | Thus, the primary aims of the present review were to summarize and evaluate the effects of acupuncture on local microcirculation and to compare the blood flow changes induced by acupuncture among five types of typical control groups: no-acupuncture, nonpenetrating acupuncture at same acupoint, superficial acupuncture, acupuncture needling at a nonacupoint, and insertion-only without manipulation. | Evid Based Complement Alternat Med. 2016;2016:9874207. doi: 10.1155/2016/9874207. Epub 2016 Jun 14. | Microcirculation Blood Flow | Review |
| 27403201 | In the studies that assessed patients with fibromyalgia and trapezius myalgia, the sensitivity of microcirculation to acupuncture needling varied according to patient characteristics. | Evid Based Complement Alternat Med. 2016;2016:9874207. doi: 10.1155/2016/9874207. Epub 2016 Jun 14. | Microcirculation | Review |
| 27403201 | The subsequent study from this group revealed that acupuncture performed at GB21 (on the back of the shoulder located on the trapezius muscle), where the trapezius myalgia and fibromyalgia patients suffered pain, produced different patterns of microcirculation. | Evid Based Complement Alternat Med. 2016;2016:9874207. doi: 10.1155/2016/9874207. Epub 2016 Jun 14. | Microcirculation | Review |
| 27403201 | reported a transient reduction in skin microcirculation following acupuncture at a nearby fingertip and the transient effects of acupuncture stimulation on transient sympathetic activation. | Evid Based Complement Alternat Med. 2016;2016:9874207. doi: 10.1155/2016/9874207. Epub 2016 Jun 14. | Microcirculation | Review |
| 27403201 | In the two studies of patients with fibromyalgia or trapezius myalgia, there were significant increases in blood flow in the skin and muscle, but the sensitivity of microcirculation to the acupuncture needling varied depending on the characteristics of disease. | Evid Based Complement Alternat Med. 2016;2016:9874207. doi: 10.1155/2016/9874207. Epub 2016 Jun 14. | Microcirculation Blood Flow | Review |
| 27403201 | Clinical Aspects of Microcirculation Measures: Differences between Healthy Subjects and Patients in Microcirculation Changes after Acupuncture | Evid Based Complement Alternat Med. 2016;2016:9874207. doi: 10.1155/2016/9874207. Epub 2016 Jun 14. | Microcirculation | Review |
| 27403201 | studied whether acupuncture-induced changes in local microcirculation could have a clinical influence and found that the repeated manipulation of LI4 enhanced local microcirculation and increased the analgesic effects compared with single manipulations or insertion-only. | Evid Based Complement Alternat Med. 2016;2016:9874207. doi: 10.1155/2016/9874207. Epub 2016 Jun 14. | Analgesic Effect Microcirculation | Review |
| 27403201 | Additionally, these two parameters were correlated, which indicates that local increases in microcirculation might influence the analgesic effects of acupuncture. | Evid Based Complement Alternat Med. 2016;2016:9874207. doi: 10.1155/2016/9874207. Epub 2016 Jun 14. | Analgesic Effect Microcirculation | Review |
| 27403201 | reported a reduction in skin microcirculation immediately following acupuncture treatment. | Evid Based Complement Alternat Med. 2016;2016:9874207. doi: 10.1155/2016/9874207. Epub 2016 Jun 14. | Microcirculation | Review |
| 27403201 | also reported that acupuncture induced an immediate reduction in microcirculation that returned to normal levels within 1 minute. | Evid Based Complement Alternat Med. 2016;2016:9874207. doi: 10.1155/2016/9874207. Epub 2016 Jun 14. | Microcirculation | Review |
| 27403201 | The studies selected for the present review propose several possible mechanisms that may underlie the changes in microcirculation following acupuncture treatment. | Evid Based Complement Alternat Med. 2016;2016:9874207. doi: 10.1155/2016/9874207. Epub 2016 Jun 14. | Microcirculation | Review |
| 27403201 | It suggested here that the increased blood perfusion induced by acupuncture stimulation might be relevant to the suppression of the sympathetic nerve activity and the vasodilation in local microvascular beds. | Evid Based Complement Alternat Med. 2016;2016:9874207. doi: 10.1155/2016/9874207. Epub 2016 Jun 14. | Microcirculation | Review |
| 28933377 | Thus, more and more attention has been focused on the relationship of acupuncture and circulation. | Medicines (Basel). 2014 Nov 20;1(1):56-63. doi: 10.3390/medicines1010056. | Circulation | Review |
| 28933377 | A schematic diagram of the relationship between acupuncture stimulation, changes of microcirculation and mast cells is presented as result. | Medicines (Basel). 2014 Nov 20;1(1):56-63. doi: 10.3390/medicines1010056. | Microcirculation | Review |
| 28933377 | Thus, more and more attention has been focused on the relationship of acupuncture and circulation. | Medicines (Basel). 2014 Nov 20;1(1):56-63. doi: 10.3390/medicines1010056. | Circulation | Review |
| 28933377 | In the research area of microcirculation, laser Doppler flowmetry (LDF) is widely being used for monitoring the microcirculation due to its advantage of a good frequency response, and is therefore well suited for noninvasive investigations of microvascular responses to acupuncture. | Medicines (Basel). 2014 Nov 20;1(1):56-63. doi: 10.3390/medicines1010056. | Microcirculation | Review |
| 28933377 | It has also been shown that acupuncture cannot only increase general circulation and circulation in specific organs, but it can also change the skin microcirculation as well. | Medicines (Basel). 2014 Nov 20;1(1):56-63. doi: 10.3390/medicines1010056. | Microcirculation Circulation | Review |
| 28933377 | Previous results indicated that acupuncture can regulate microcirculation. | Medicines (Basel). 2014 Nov 20;1(1):56-63. doi: 10.3390/medicines1010056. | Microcirculation | Review |
| 28933377 | However, acupuncture and the circulation response can be related via an intermediate bridge. | Medicines (Basel). 2014 Nov 20;1(1):56-63. doi: 10.3390/medicines1010056. | Circulation | Review |
| 28933377 | Block diagram of the relationship between acupuncture stimulation, changes of microcirculation, and mast cells. | Medicines (Basel). 2014 Nov 20;1(1):56-63. doi: 10.3390/medicines1010056. | Microcirculation | Review |
| 29080196 | According the description of CM, acupoints are located along meridian lines on the body surface, and acupuncture stimulates acupoints through regulation of the environmental balance of circulating the vital energy and blood through meridian system. | Chin J Integr Med. 2017 Nov;23(11):812-815. doi: 10.1007/s11655-017-2789-x. Epub 2017 Oct 28. | Circulation | Review |
| 29080196 | It is postulated that acupuncture stimulation improves local circulation and allows for a flush of algesic or sensitizing substances, leading to pain relief. | Chin J Integr Med. 2017 Nov;23(11):812-815. doi: 10.1007/s11655-017-2789-x. Epub 2017 Oct 28. | Pain Relief Circulation | Review |
| 29080196 | Acupuncture induces an elevation of vasodilator (NO) release over skin regions, and elevated NO improves local circulation, which contribute to local warmness and the beneficial effects of acupuncture such as pain relief, improvements of sweating, and inflammation. | Chin J Integr Med. 2017 Nov;23(11):812-815. doi: 10.1007/s11655-017-2789-x. Epub 2017 Oct 28. | Pain Relief Circulation | Review |
| 29722298 | Acupuncture intervention can significantly reduce the size of the infarcted area, improve cerebral blood circulation to promote regional energy metabolism, regulate blood lipid metabolism to resist cerebral free radical damage, inhibit cerebral cortical apoptosis, reduce the amount of excitatory amino acids to lower neurogenic toxicity, reduce calcium overloading, ease cerebral vascular immune-inflammatory reactions, and upregulate the expression of antiapoptosis genes and neurotrophic factors, thereby promoting the proliferation and differentiation of neural stem cells in the focal cerebral cortex and hippocampus. | Neural Regen Res. 2018 Apr;13(4):573-583. doi: 10.4103/1673-5374.230272. | Immunity Toxic Side Effects Circulation | Review |
| 29729027 | The way to restore energy, circulation, health, and balance is to stimulate the appropriate combination of the estimated 400 traditional meridian acupuncture points on the body. | Cochrane Database Syst Rev. 2018 May 5;5(5):CD013010. doi: 10.1002/14651858.CD013010. | Circulation | Review |
| 29844696 | According to traditional medical theory, acupuncture stimulation facilitates the flow of qi, a life force that is supposedly circulating through the channels called meridians. | J Inflamm Res. 2018 May 17;11:227-237. doi: 10.2147/JIR.S141198. eCollection 2018. | Circulation | Review |
| 29941854 | According to Robinson, acupuncture points BL 23, BL 24 and BL 26 improve circulation to the local tissues and resolve myofascial dysfunction and promote tissue recovery. | Medicines (Basel). 2018 Jun 25;5(3):63. doi: 10.3390/medicines5030063. | Circulation | Review |
| 30050856 | Acupuncture has also been shown to cause vasodilation by increasing the release of vasodilatory peptides such as calcitonin gene-related peptide and vasoactive intestinal polypeptide, which serve to improve circulation and tissue healing. | Vet Med (Auckl). 2017 Aug 24;8:53-58. doi: 10.2147/VMRR.S125609. eCollection 2017. | Circulation | Review |
| 30298094 | Scalp acupuncture has been reported to (1) improve cerebral blood circulation, promoting regional energy metabolism; (2) upregulate expression of glial cell-line derived neurotrophic factor (GDNF), possibly promoting proliferation and differentiation of neural stem cells in the focal cerebral cortex and hippocampus; (3) reduce contents of excitatory amino acid and increase level of GABA, thus lowering neurogenic toxicity; (4) ease cerebral vascular immunoinflammatory reactions; (5) regulate blood lipid metabolism to resist cerebral free radical damage; and (6) inhibit cerebral cortical apoptosis. | Evid Based Complement Alternat Med. 2018 Sep 12;2018:8107508. doi: 10.1155/2018/8107508. eCollection 2018. | Immunity Toxic Side Effects Circulation | Review |
| 30854010 | After acupuncture treatment, the active component such as 5-Hydroxytryptamine (5-HT) and Histamine (HB) in the gastrointestinal microcirculation decreased in obese patients, while prostaglandin E2(PGE2) increased on the effected side. | Evid Based Complement Alternat Med. 2019 Feb 3;2019:5796381. doi: 10.1155/2019/5796381. eCollection 2019. | Microcirculation Side Effects | Review |
| 30854010 | Acupuncture significantly decreased the glucose level with a diet restriction that entailed a 1450 kilocalorie (kcal) diet program once a day for 30 min over 20 days, indicating that acupuncture could regulate the circulation of blood glucose in obese patients. | Evid Based Complement Alternat Med. 2019 Feb 3;2019:5796381. doi: 10.1155/2019/5796381. eCollection 2019. | Circulation | Review |
| 30855351 | Secondly, the rational application of acupuncture during surgery also aids in stabilizing the intraoperative respiratory and circulatory functions and relieving the surgical and anesthesia stress. | Chin Med J (Engl). 2019 Mar 20;132(6):707-715. doi: 10.1097/CM9.0000000000000123. | Circulation | Review |
| 30915143 | Some researchers have shown that electroacupuncture can increase the quantity of CGRP and SP in peripheral tissues and in blood circulation. | Evid Based Complement Alternat Med. 2019 Feb 24;2019:2326867. doi: 10.1155/2019/2326867. eCollection 2019. | Circulation | Review |
| 30984420 | Studies have reported that acupuncture can improve cerebral blood flow and increase microvascular openings in the hippocampus CA1 area by increasing the proportion of Bcl-2/Bax and inhibiting apoptosis, in order to lower BP and prevent target organ damage. | Int J Hypertens. 2019 Mar 7;2019:8676490. doi: 10.1155/2019/8676490. eCollection 2019. | Microcirculation Blood Pressure Blood Flow | Review |
| 31467579 | Current research shows that acupuncture has a definite curative effect on the treatment of cerebral ischemia-reperfusion injury, and it plays an important role in improving microcirculation, improving brain electrical activity, and inhibiting oxygen-free radicals, thereby greatly reducing nerve injury. | Evid Based Complement Alternat Med. 2019 Jul 31;2019:8138017. doi: 10.1155/2019/8138017. eCollection 2019. | Microcirculation | Review |
| 32215037 | Acupuncture therapies were reported significantly decreasing intestinal microvascular permeability and improving microcirculation, protecting intestinal epithelial cells from inflammatory response in sepsis. | Evid Based Complement Alternat Med. 2020 Mar 7;2020:3620741. doi: 10.1155/2020/3620741. eCollection 2020. | Microcirculation | Review |
| 32590807 | They found that acupuncture significantly increased uterine wall thickness and improved uterine blood circulation in rats. | Medicine (Baltimore). 2020 Jun 26;99(26):e20958. doi: 10.1097/MD.0000000000020958. | Circulation | Review |
| 32714268 | Compared with medication, acupuncture showed higher effectiveness with less adverse reactions and improved intracranial blood circulation. | Front Neurol. 2020 Jun 30;11:596. doi: 10.3389/fneur.2020.00596. eCollection 2020. | Adverse Reactions Circulation | Review |
| 32714268 | While acupuncture demonstrably attenuates and prevents migraine, and improves intracranial blood circulation, its curative effect in migraine remains controversial, due to the periodicity of the condition. | Front Neurol. 2020 Jun 30;11:596. doi: 10.3389/fneur.2020.00596. eCollection 2020. | Circulation | Review |
| 33327222 | Based on the principles of traditional medicine, acupuncture regulates energy pathways and controls the balance of energy circulation to alleviate various symptoms of cancer, as evidenced by the changes in neurophysiologic and neurohormonal activities. | Medicine (Baltimore). 2020 Dec 11;99(50):e21820. doi: 10.1097/MD.0000000000021820. | Circulation | Review |
| 34281592 | In these models, TNF-α may be secreted from circulating M1 monocytes or tissue-derived macrophages, thus the SNS and its transmitters may mediate macrophage polarization induced by acupuncture. | Chin Med. 2021 Jul 19;16(1):56. doi: 10.1186/s13020-021-00466-7. | Circulation | Review |
| 34306150 | Based on a large number of clinical and animal experiments, the different mechanisms of acupuncture treatment for dysmenorrhea include relaxation of the meridians and promotion of blood circulation, modulation of immunity, activation of various neurotransmitters, reduction of VEGF, and regulation of abnormal prostaglandins, β-endorphin, dynorphin, electrolytes, and substance P levels in the body. | Evid Based Complement Alternat Med. 2021 Jul 2;2021:6663602. doi: 10.1155/2021/6663602. eCollection 2021. | Immunity Circulation | Review |
| 34306150 | Direct stimulation can be carried out on the transtendon point through electric conduction, and the current can reach areas that acupuncture needles cannot reach, which can effectively improve blood circulation. | Evid Based Complement Alternat Med. 2021 Jul 2;2021:6663602. doi: 10.1155/2021/6663602. eCollection 2021. | Circulation | Review |
| 34397828 | Acupuncture stimulates acupuncture points on the patient's body surface and conducts them through the meridians throughout the body to relieve spasm and pain, promote blood circulation and remove blood stasis, and dredge the meridians. | Medicine (Baltimore). 2021 Aug 6;100(31):e26785. doi: 10.1097/MD.0000000000026785. | Circulation | Review |
| 34489662 | Specifically, the main roles of moxibustion at GB34 are to warm the meridians, regulate Qi, and promote blood circulation, to relieve pain, EA at GB34 mainly focused on treating the motor system, and fire acupuncture at GB34 showed both above effects. | Front Hum Neurosci. 2021 Aug 20;15:694919. doi: 10.3389/fnhum.2021.694919. eCollection 2021. | Circulation | Review |
| 34521235 | Finally, since the efficacy of the different control groups is still uncertain, we suggest that in future studies, pneumatic circulation or routine care could be used for comparison in addition to waiting lists or sham acupuncture control. | Integr Cancer Ther. 2021 Jan-Dec;20:15347354211044107. doi: 10.1177/15347354211044107. | Circulation | Review |
| 34992414 | This study comprehensively reviews and presents literature from the last five years, showing that acupuncture indeed exerts strong anti-inflammatory effects in multiple biological systems, namely, the immune, digestive, respiratory, nervous, locomotory, circulatory, endocrine, and genitourinary systems. | J Inflamm Res. 2021 Dec 21;14:7191-7224. doi: 10.2147/JIR.S341581. eCollection 2021. | Immunity Gastrointestinal Tract Endocrinology Circulation | Review |
| 34992414 | Several lines of evidence have confirmed that acupuncture effectively treats circulatory system diseases and adjusts the levels of a variety of chemical components, such as plasma proteins, blood ammonia, electrolytes, enzyme activities, and other biological active substances to regulate vascular function, promote the formation of collateral neovascularization, improve the microcirculation, and enhance the remodeling of ventricular function. | J Inflamm Res. 2021 Dec 21;14:7191-7224. doi: 10.2147/JIR.S341581. eCollection 2021. | Microcirculation Circulation | Review |
| 35002950 | As suggested in this study, the main treatment theories for T2DM in TCM are to invigorate the kidney and promote blood circulation, invigorate Qi, and dissipate blood stasis, which is achieved by taking TCM medicine or external treatments (e.g., acupuncture and moxibustion). | Front Endocrinol (Lausanne). 2021 Dec 23;12:728032. doi: 10.3389/fendo.2021.728032. eCollection 2021. | Kidney Circulation | Review |
| 35241146 | Clinical and laboratory evidence suggests that acupuncture induces multilevel regulation through complex mechanisms against cerebral ischemia, including: (1) neuroprotection, (2) collateral circulation reconstruction, (3) neuro-regeneration, and (4) modulating brain glucose metabolism and brain plasticity. | Stem Cell Res Ther. 2022 Mar 3;13(1):87. doi: 10.1186/s13287-022-02761-y. | Neuroprotection Circulation | Review |
| 35241146 | b Acupuncture intervention may be applied in any stage of stroke with various therapeutic effects that promote the development of collateral circulation and prevent further brain damage at the acute phase and stimulate endogenous neurogenesis at the post-acute phase. | Stem Cell Res Ther. 2022 Mar 3;13(1):87. doi: 10.1186/s13287-022-02761-y. | Circulation | Review |
| 35241146 | Acupuncture has been shown to increase CBF and improve microcirculation, which could potentially explain the beneficial effects of acupuncture on treating cerebral ischemia. | Stem Cell Res Ther. 2022 Mar 3;13(1):87. doi: 10.1186/s13287-022-02761-y. | Microcirculation | Review |
| 35241146 | Both animal and clinical studies have proved that acupuncture can increase the cerebral blood flow and cerebral microcirculation by regulating the expression of angiogenesis-related factors, which result in a more conducive microenvironment for the survival of transplanted stem cells and the regeneration of NVUs at the infarct site. | Stem Cell Res Ther. 2022 Mar 3;13(1):87. doi: 10.1186/s13287-022-02761-y. | Microcirculation Blood Flow | Review |
| 35310023 | The principle of shallow acupuncture is to stimulate the meridian blood circulation through the physical stimulation of the meridian points by the needle tip, adjust the functional balance of the meridians and viscera, and play the role of strengthening the body, eliminating pathology and curing diseases. | Evid Based Complement Alternat Med. 2022 Mar 11;2022:2447529. doi: 10.1155/2022/2447529. eCollection 2022. | Circulation | Review |
| 35399635 | Based on a large number of clinical and animal experiments, the different mechanisms of acupuncture treatment for POI include relaxation of the meridians and promotion of blood circulation, regulation of the hypothalamus-pituitary-ovarian axis, improvement of hormone levels, increasing the production of the antiapoptotic factor Bcl-2, and reducing the production of the proapoptotic factor Bax in ovarian granulosa cells. | Evid Based Complement Alternat Med. 2022 Apr 1;2022:9053930. doi: 10.1155/2022/9053930. eCollection 2022. | Circulation | Review |
| 35399635 | Electroacupuncture can adjust human physiological functions, relieve pain, provide sedation, promote blood circulation, reduce muscle tension, and so on. | Evid Based Complement Alternat Med. 2022 Apr 1;2022:9053930. doi: 10.1155/2022/9053930. eCollection 2022. | Circulation Sedation | Review |
| 35462893 | Acupuncture-induced neuroprotection includes several mechanisms such as reducing oxidative stress, inhibiting the inflammatory response and neuronal apoptosis, alleviating glial scar formation, promoting neural stem cell differentiation, and improving microcirculation within the injured area. | Front Pharmacol. 2022 Apr 7;13:875103. doi: 10.3389/fphar.2022.875103. eCollection 2022. | Neuroprotection Microcirculation | Review |
| 35462893 | Clinical studies conducted in healthy adults demonstrated that acupuncture influences the tortuousness of capillary loops, the diameter of the afferent loop, and capillary refill time, thereby regulating the microcirculation. | Front Pharmacol. 2022 Apr 7;13:875103. doi: 10.3389/fphar.2022.875103. eCollection 2022. | Microcirculation | Review |
| 35462893 | In addition, a study using the intervertebral disc extrusion model revealed that electroacupuncture improves microcirculation characterized by high blood flow, micro-vessel density, and reduced vacuolation within the white matter. | Front Pharmacol. 2022 Apr 7;13:875103. doi: 10.3389/fphar.2022.875103. eCollection 2022. | Microcirculation Blood Flow | Review |
| 35462893 | Acupuncture can also regulate microcirculation and attenuate neurological dysfunction by suppressing the cPLA2 activity and PGE2 level. | Front Pharmacol. 2022 Apr 7;13:875103. doi: 10.3389/fphar.2022.875103. eCollection 2022. | Microcirculation | Review |
| 35462893 | We explained in detail the underlying mechanisms of acupuncture therapy for SCI, including oxidative stress reduction, inflammation and apoptosis inhibition, microcirculation improvement, glial scar formation reduction, and stimulation of NSC differentiation (Figure 1). | Front Pharmacol. 2022 Apr 7;13:875103. doi: 10.3389/fphar.2022.875103. eCollection 2022. | Microcirculation | Review |
| 35462893 | Illustration of the possible mechanism underlying acupuncture therapy in SCI, including oxidative stress reduction, inflammation and apoptosis inhibition, microcirculation improvement, reduction of glial scar formation, and stimulation of NSC differentiation and proliferation. | Front Pharmacol. 2022 Apr 7;13:875103. doi: 10.3389/fphar.2022.875103. eCollection 2022. | Microcirculation | Review |
| 35494482 | Substantial evidence was reported of acupuncture's effect on the cerebral perfusion and angiogenesis promotion in the cerebral ischemic condition, indicating that the boom of collateral circulation which plays as a compensatory part might be a potent pathophysiologic basis. | Neural Plast. 2022 Apr 21;2022:5635596. doi: 10.1155/2022/5635596. eCollection 2022. | Circulation | Review |
| 35570887 | Secondly, electro-acupuncture can circulate the blood flow of the uterus, reduce the resistance of uterine arteries, and increase ovarian blood flow through the ovarian sympathetic nerves. | Front Public Health. 2022 Apr 28;10:858587. doi: 10.3389/fpubh.2022.858587. eCollection 2022. | Circulation Blood Flow | Review |
| 35600949 | Therefore, to explore whether acupuncture can regulate BA circulation and NRs expression and then participate in the disease progression of CD, a new theoretical basis for acupuncture treatment of CD is provided. | Evid Based Complement Alternat Med. 2022 May 13;2022:5814048. doi: 10.1155/2022/5814048. eCollection 2022. | Circulation | Review |
| 35600949 | Therefore, this review is designed to explore the mechanism of NRs in CD in the gut-liver circulation of BAs and the regulatory effect of acupuncture. | Evid Based Complement Alternat Med. 2022 May 13;2022:5814048. doi: 10.1155/2022/5814048. eCollection 2022. | Circulation | Review |
| 35600949 | Acupuncture and moxibustion have the functions of dredging meridians, anti-inflammatory and analgesic, warming meridians, warming and dispersing cold evil, eliminating swelling and knot, promoting blood circulation, and removing blood stasis. | Evid Based Complement Alternat Med. 2022 May 13;2022:5814048. doi: 10.1155/2022/5814048. eCollection 2022. | Circulation Inflammatory Pain | Review |
| 35600949 | It is confirmed from the above limited research has confirmed that acupuncture and moxibustion can regulate the liver-intestinal circulation of cholesterol and participate in related pathways mediated by NRs. | Evid Based Complement Alternat Med. 2022 May 13;2022:5814048. doi: 10.1155/2022/5814048. eCollection 2022. | Circulation | Review |
| 35600949 | Combined with the study of the therapeutic mechanism of acupuncture and moxibustion, and the related role of BAs-NRs in gut-liver circulation, we speculate that in the treatment of CD, acupuncture and moxibustion cause the increase of BAs synthesis in the liver by stimulating local acupoints and through the signal input of nervous and humor system. | Evid Based Complement Alternat Med. 2022 May 13;2022:5814048. doi: 10.1155/2022/5814048. eCollection 2022. | Circulation | Review |
| 35600949 | Therefore, exploring whether acupuncture and moxibustion can participate in the disease progression of CD by regulating BA circulation and the expression of NRs can provide a new theoretical basis for acupuncture and moxibustion in the treatment of CD. | Evid Based Complement Alternat Med. 2022 May 13;2022:5814048. doi: 10.1155/2022/5814048. eCollection 2022. | Circulation | Review |
| 35600949 | Effects of acupuncture and moxibustion on gut-liver circulation of BAs and the mechanism of regulating NRs. | Evid Based Complement Alternat Med. 2022 May 13;2022:5814048. doi: 10.1155/2022/5814048. eCollection 2022. | Circulation | Review |
| 35737304 | Physiologically, all acupuncture points share the same effects including fibroblast mechanotransduction, fascial interaction, neuromodulation leading to analgesia, fluid motion modulation and the manipulation of the microvascular environment.. Some points may specifically cause immune modulation, affect the autonomic nervous system, visceral organs, or the brain, modulate lymphatic flow or cause neuromuscular effects. | Vet Sci. 2022 May 26;9(6):252. doi: 10.3390/vetsci9060252. | Immunity Microcirculation | Review |
| 35737304 | The segmental effects of acupuncture can provide pain relief, improve circulation and healing, and increase mobilization. | Vet Sci. 2022 May 26;9(6):252. doi: 10.3390/vetsci9060252. | Pain Relief Circulation | Review |
| 35800002 | Cerebral Blood Flow Velocity Modulation and Clinical Efficacy of Acupuncture for Posterior Circulation Infarction Vertigo: A Systematic Review and Meta-Analysis | Evid Based Complement Alternat Med. 2022 Jun 28;2022:3740856. doi: 10.1155/2022/3740856. eCollection 2022. | Circulation Blood Flow | Review |
| 35800002 | Acupuncture is demonstrated to have a beneficial effect on posterior circulation infarction vertigo (PCIV). | Evid Based Complement Alternat Med. 2022 Jun 28;2022:3740856. doi: 10.1155/2022/3740856. eCollection 2022. | Circulation | Review |
| 35800002 | A total of 20 eligible RCTs (1541 participants) were included in this review, which compared acupuncture therapy (1 RCT) or acupuncture combined with pharmaceutical therapy (19 RCTs) to pharmaceutical therapy in patients with posterior circulation infarction vertigo. | Evid Based Complement Alternat Med. 2022 Jun 28;2022:3740856. doi: 10.1155/2022/3740856. eCollection 2022. | Circulation | Review |
| 35800002 | This study shows that acupuncture therapy is useful in improving the blood flow velocity of vertebrobasilar arteries and Clinical Effective Rate in patients with posterior circulation infarction vertigo. | Evid Based Complement Alternat Med. 2022 Jun 28;2022:3740856. doi: 10.1155/2022/3740856. eCollection 2022. | Circulation Blood Flow | Review |
| 35800002 | The results of our research provided the following implications for clinical practice and further studies: Firstly, this study proved that compared to pharmaceutic therapy, acupuncture therapy alone or acupuncture combined with pharmaceutic therapy was more effective in the treatment of posterior circulation infarction vertigo. | Evid Based Complement Alternat Med. 2022 Jun 28;2022:3740856. doi: 10.1155/2022/3740856. eCollection 2022. | Circulation | Review |
| 35800002 | Modern medical research indicates that acupuncture GB 20 can improve cerebral posterior circulation. | Evid Based Complement Alternat Med. 2022 Jun 28;2022:3740856. doi: 10.1155/2022/3740856. eCollection 2022. | Circulation | Review |
| 35800002 | This study suggests that acupuncture therapy improves the blood flow velocity of vertebrobasilar arteries and Clinical Effective Rate in patients with posterior circulation infarction vertigo. | Evid Based Complement Alternat Med. 2022 Jun 28;2022:3740856. doi: 10.1155/2022/3740856. eCollection 2022. | Circulation Blood Flow | Review |
| 35800002 | However, double-blind, sham-controlled trials with large sample sizes are required to further verify acupuncture's therapeutic efficacy in posterior circulation infarction vertigo. | Evid Based Complement Alternat Med. 2022 Jun 28;2022:3740856. doi: 10.1155/2022/3740856. eCollection 2022. | Circulation | Review |
| 35884060 | Research indicates acupuncture may have local and distal actions, as well as influences on human biochemistry, the nervous system, circulatory system, immune system, and fascial networks. | Children (Basel). 2022 Jul 19;9(7):1076. doi: 10.3390/children9071076. | Immunity Circulation | Review |
| 35922617 | The inhibitory effect of acupuncture on nausea and vomiting may be through the following mechanisms: (1) blocking the transmission of 5-HT3 and increasing the release of endogenous β-endorphins in the cerebrospinal fluid; (2) regulating the function of the vagus nerve, the secretion of hormones, and the blood circulation of the gastrointestinal tract; and (3) playing an indirect preventive effect by reducing the application of opioid analgesics. | Pain Ther. 2022 Dec;11(4):1095-1112. doi: 10.1007/s40122-022-00415-8. Epub 2022 Aug 3. | Gastrointestinal Tract Nausea and Vomiting Circulation | Review |
| 35968313 | Evidence has shown that acupuncture improves cerebral circulation, relieves pain, and modulates neural function. | Front Neurol. 2022 Jul 22;13:930753. doi: 10.3389/fneur.2022.930753. eCollection 2022. | Circulation | Review |
| 35968313 | ST36 acupuncture is popular for analgesia, cognitive function and cerebral circulation improvement, and gastrointestinal disease regulation in modern practices. | Front Neurol. 2022 Jul 22;13:930753. doi: 10.3389/fneur.2022.930753. eCollection 2022. | Cognitive Function Circulation | Review |
| 35983251 | Meanwhile, they also mentioned that acupuncture can dredge the meridians and collaterals of spasms of upper limbs, make the blood circulation of the affected limbs smooth, and thus enhance the spasmodic state of the affected limbs. | Biomed Res Int. 2022 Aug 9;2022:8663356. doi: 10.1155/2022/8663356. eCollection 2022. | Circulation | Review |
| 35983251 | Acupuncture can obviously protect against cerebral ischemic injury, improve cerebral blood flow, promote the establishment of collateral circulation in cerebral necrotic area, activate nerve cell and nerve fiber regeneration, enhance brain cell ischemia and hypoxia, and finally affect the smooth flow of memory loop. | Biomed Res Int. 2022 Aug 9;2022:8663356. doi: 10.1155/2022/8663356. eCollection 2022. | Circulation Blood Flow | Review |
| 36313493 | Acupuncture therapies were used alone or combined with conventional therapy (CT, including recanalization treatments, controlling vascular risk factors, improving blood circulation, and protecting brain cells). | Front Neurol. 2022 Oct 13;13:1005819. doi: 10.3389/fneur.2022.1005819. eCollection 2022. | Brain Protection Circulation | Review |
| 36353235 | Evidence has shown that acupuncture elevates the level of β-endorphin not only in the central endocrine system but also in the peripheral circulation, which is associated with both direct and indirect tonic inhibitions of GnRH and subsequent LH release. | Front Endocrinol (Lausanne). 2022 Oct 24;13:1035929. doi: 10.3389/fendo.2022.1035929. eCollection 2022. | Endocrinology Circulation | Review |
| 36388196 | Scalp acupuncture inhibited the increase of peripheral plasma ET-1 in patients with cerebral infarction, contributing to the improvement of vascular elasticity and cerebral blood circulation as well as the reduction of the disability rate (Figure 2 and Table 2). | Front Neurol. 2022 Oct 28;13:1030747. doi: 10.3389/fneur.2022.1030747. eCollection 2022. | Circulation | Review |
| 36388196 | Acupuncture modulates microcirculation | Front Neurol. 2022 Oct 28;13:1030747. doi: 10.3389/fneur.2022.1030747. eCollection 2022. | Microcirculation | Review |
| 36388196 | Furthermore, acupuncture effectively dilated the diameter of microvessels and augmented the blood flow of the leptomeningeal microcirculation (Table 4). | Front Neurol. 2022 Oct 28;13:1030747. doi: 10.3389/fneur.2022.1030747. eCollection 2022. | Microcirculation Blood Flow | Review |
| 36388196 | Therefore, it is reasonable to infer that acupuncture may enhance microcirculation through the regulation of key enzymes in cell metabolism, thereby improving neurological function prognosis in ischemic stroke. | Front Neurol. 2022 Oct 28;13:1030747. doi: 10.3389/fneur.2022.1030747. eCollection 2022. | Microcirculation | Review |
| 36388196 | In the meantime, acupuncture improved microcirculation, enhancing energy metabolism of brain tissues and ameliorating neurological function prognosis (Figure 6). | Front Neurol. 2022 Oct 28;13:1030747. doi: 10.3389/fneur.2022.1030747. eCollection 2022. | Microcirculation | Review |
| 36482537 | Acupoint therapies such as acupuncture, massage, and moxibustion modify the operation of the meridians by acting on the acupoints to adjust Qi-blood circulation of the body and treat diseases. | Medicine (Baltimore). 2022 Dec 2;101(48):e32058. doi: 10.1097/MD.0000000000032058. | Circulation | Review |
| 36607887 | CPBA frequently and significantly increases the heart rate, and existing studies show that acupuncture anesthesia excites the vagus nerve, dilates blood vessels, reduces peripheral circulation resistance. | Medicine (Baltimore). 2023 Jan 6;102(1):e32582. doi: 10.1097/MD.0000000000032582. | Heart Rate Circulation | Review |
| 36670425 | reported that acupuncture at GV20 improved cognitive dysfunction induced by scopolamine, alleviated the decline in hippocampal ChAT levels, and restored the expression of the hippocampal choline transporter 1 and vesicular acetylcholine transporter, suggesting that acupuncture may regulate ACh metabolism, and may contribute to the circulation of choline from the synaptic cleft back to the presynaptic terminal, and improve the efficiency of vesicle filling. | Chin Med. 2023 Jan 20;18(1):8. doi: 10.1186/s13020-023-00707-x. | Cognitive Function Circulation | Review |
| 36684056 | The role of acupuncture in HCC is to regulate the ying and yang, as well as improve body circulation. | World J Gastrointest Oncol. 2023 Jan 15;15(1):19-35. doi: 10.4251/wjgo.v15.i1.19. | Circulation | Review |
| 36684056 | Meanwhile, a randomized controlled trial by Wei et al studied 72 cases who received acupuncture on RN 8 and RN 12, reporting improved portal circulation. | World J Gastrointest Oncol. 2023 Jan 15;15(1):19-35. doi: 10.4251/wjgo.v15.i1.19. | Circulation | Review |
| 36684056 | Taken together, these studies indicate that acupuncture may enhance circulation in the liver and portal area and decrease HCC progression. | World J Gastrointest Oncol. 2023 Jan 15;15(1):19-35. doi: 10.4251/wjgo.v15.i1.19. | Circulation | Review |
| 36698826 | Objective outcome indicators, such as time to complete pain relief, episodes of renal colic during treatment and adverse effects as well as circulating prostaglandin E2 concentration, may be included in future studies to provide more accurate information for elucidating the beneficial effects of acupuncture in this clinical setting. | Front Med (Lausanne). 2023 Jan 9;9:1100014. doi: 10.3389/fmed.2022.1100014. eCollection 2022. | Pain Relief Adverse Reactions Kidney Circulation | Review |
| 36845424 | Especially in scalp acupuncture, some special acupoints, such as DU-20 and X-HN1, may expand the blood vessels of the corresponding brain areas or promote collateral circulation. | Front Neurosci. 2023 Feb 8;17:1097477. doi: 10.3389/fnins.2023.1097477. eCollection 2023. | Circulation | Review |
| 36864974 | In terms of centrality, Clin Exp Hypertens (Clinical and Experimental Hypertension) (0.19) ranks highest, with Acupunct Med (Acupuncture in Medicine) (0.13), Acupuncture Electro (Acupuncture & Electro-Therapeutics Research) (0.11), Am J Physiol-Heart C (American Journal of Physiology-Heart and Circulatory Physiology) (0.11) and Am J Cardiol (American Journal of Cardiology) (0.11) rankings second to fifth in the order. | Cardiovasc Diagn Ther. 2023 Feb 28;13(1):67-82. doi: 10.21037/cdt-22-480. Epub 2022 Dec 15. | Circulation | Review |
| 36865050 | Regarding the time point of acupuncture for CPCR, since neurological impairment is initiated during circulatory interruption and accentuated during the reperfusion phase, while the recovery time of ROSC was independently related to brain injury and the neurological function prognosis at discharge. | Integr Med Res. 2023 Mar;12(1):100925. doi: 10.1016/j.imr.2023.100925. Epub 2023 Feb 5. | Circulation | Review |
| 37038228 | Acupuncture is mainly recommended for diseases involving the digestive system, circulatory system, and neurodevelopmental disorders, with studies showing that its efficacy is superior to conventional treatment. | Chin Med. 2023 Apr 10;18(1):38. doi: 10.1186/s13020-023-00743-7. | Gastrointestinal Tract Circulation | Review |
| 37091130 | Acupuncture therapy can reduce whole blood viscosity to increase the elasticity of cerebral arteries, reduce vascular tension, and improve blood viscosity and aggregation to improve cerebral blood flow and promote blood circulation. | Behav Neurol. 2023 Apr 12;2023:9445381. doi: 10.1155/2023/9445381. eCollection 2023. | Circulation Blood Flow | Review |
| 37091130 | We reviewed previous research and found that, based on two models of aphasia, the research on the mechanism of acupuncture treatment in PSA mainly concerns: (1) the single acupoint for the activation of different cortical areas in aphasia patients; and (2) acupuncture improves blood circulation, increases cerebral blood flow, restores the blood supply of damaged brain tissue, and improves hemorheology. | Behav Neurol. 2023 Apr 12;2023:9445381. doi: 10.1155/2023/9445381. eCollection 2023. | Circulation Blood Flow | Review |
| 37139070 | Due to their capacity to stimulate the repair and regeneration of injured nerves, enhance local blood circulation in the treated area, and lessen postoperative pain, acupuncture and tui na are widely used in traditional Chinese medicine to treat brachial plexus nerve injury. | Front Neurol. 2023 Apr 17;14:1084223. doi: 10.3389/fneur.2023.1084223. eCollection 2023. | Circulation | Review |
| 37397457 | In addition, acupuncture can increase intracranial blood flow rate and blood flow, improve cerebral circulation, reduce inflammatory reactions, increase brain energy metabolism, increase functional connectivity in brain regions, and thus improve cognitive level. | Front Neurosci. 2023 Jun 15;17:1211044. doi: 10.3389/fnins.2023.1211044. eCollection 2023. | Circulation Blood Flow | Review |
| 37405111 | With respect to psychological balance, acupuncture studies have been designed to relieve anxiety and depression through the regulation of circulating β-endorphins and androgens in patients with PCOS. | J Pharmacopuncture. 2023 Jun 30;26(2):105-123. doi: 10.3831/KPI.2023.26.2.105. | Anxiety Depression Circulation | Review |
| 37417606 | Furthermore, the practice of electroacupuncture to induce ovulation has been associated with circulating levels of beta-endorphin immunoactive substances and pituitary gonadotropin secretion. | Medicine (Baltimore). 2023 Jul 7;102(27):e34310. doi: 10.1097/MD.0000000000034310. | Immunity Circulation | Review |
| 37449100 | Moxibustion, a traditional Chinese medicine approach, stimulates blood circulation by burning wormwood at acupuncture points and is frequently used in conjunction with acupuncture for managing knee osteoarthritis. | Heliyon. 2023 Jul 4;9(7):e17805. doi: 10.1016/j.heliyon.2023.e17805. eCollection 2023 Jul. | Circulation | Review |
| 37449100 | Moxibustion, a traditional Chinese medicine practice, promotes blood circulation by burning wormwood at acupuncture points and is commonly used alongside acupuncture to manage musculoskeletal disorders. | Heliyon. 2023 Jul 4;9(7):e17805. doi: 10.1016/j.heliyon.2023.e17805. eCollection 2023 Jul. | Circulation | Review |
| 37467569 | The Ayurveda treatments when administered with yoga and acupuncture, help in better recovery in symptom score, and pain through improving local blood circulation, strengthening local tissues, and preserving nerve degeneration. | J Ayurveda Integr Med. 2023 Jul-Aug;14(4):100749. doi: 10.1016/j.jaim.2023.100749. Epub 2023 Jul 17. | Circulation | Review |
| 37644765 | Acupuncture can enhance cerebral blood circulation, aid in restoring brain tissue excitability, heighten the sensitivity of diverse afferent nerve impulses, thereby enhancing neural function. | Libyan J Med. 2023 Dec;18(1):2251640. doi: 10.1080/19932820.2023.2251640. | Circulation | Review |
| 37650106 | In a meta-analysis study, the effect of acupuncture was measured on the posterior circulation infarction vertigo (PCIV) that included 20 RCTs (1,541 participants). | Front Neurosci. 2023 Aug 15;17:1210537. doi: 10.3389/fnins.2023.1210537. eCollection 2023. | Circulation | Review |
| 38189090 | First, promoting blood circulation: acupuncture can stimulate the nerves and tissues around acupoints, thus increasing blood flow and microcirculation, which helps to improve the blood supply to the kidneys. | Ren Fail. 2024 Dec;46(1):2301504. doi: 10.1080/0886022X.2023.2301504. Epub 2024 Jan 8. | Microcirculation Circulation Blood Flow | Review |
| 311153 | In 800 patients studied using this type of combination of anesthetic techniques, it was found that this procedure can be successful for cardiac surgery and that it allows light planes of anesthesia with less interference to circulatory regulation. | Am J Chin Med. 1979 Spring;7(1):77-90. doi: 10.1142/s0192415x79000064. | Circulation | Clinic |
| 9387365 | During operation the patient's breathing and circulation function were stable. | Zhen Ci Yan Jiu. 1996;21(2):8-10. | Circulation | Clinic |
| 18476416 | CONCLUSION: The acupuncture-general anesthesia shows a bi-directional effect for diminishing the fluctuation of hemodynamics and stabilizing the blood circulation, and also can reduce the consumption of narcotics during operation, so it has an extensive value in clinical practice. | Zhongguo Zhong Xi Yi Jie He Za Zhi. 2008 Mar;28(3):206-8. | Hemodynamics Circulation | Clinic |
| 21739700 | The feelings of pain, circulatory index and operation effect were observed and compared. | Zhongguo Zhen Jiu. 2011 Jun;31(6):543-6. | Circulation | Clinic |
| 6662343 | The present study tests the possibility that the widespread and prolonged cutaneous vasodilation which can be produced by low-frequency TNS in patients with peripheral circulatory insufficiency is similarly dependent on a central serotonergic pathway leading to sympatho-inhibition. | Gen Pharmacol. 1983;14(6):635-41. doi: 10.1016/0306-3623(83)90160-x. | Circulation | Clinic |
| 25152761 | The Weizhong acupoint is capable of recuperating the urinary bladder from qi transformation and modulating the functioning of lower-jiao qi activity (ä¸ç¦æ°£æ©) as well as producing a quick response pain relief through fluid circulation of qi. | Evid Based Complement Alternat Med. 2014;2014:592319. doi: 10.1155/2014/592319. Epub 2014 Jul 23. | Pain Relief Circulation | Clinic |
| 29391879 | Systematic and bidirectional regulation on multiple organs can be realized via electro-acupuncture stimulation, which can not only mobilize pain suppression but also suppress physiological disorders and reduce stress responses to inhibit the inflammatory responses and maintain stable circulation. | Oncol Lett. 2018 Jan;15(1):189-194. doi: 10.3892/ol.2017.7262. Epub 2017 Oct 24. | Stress Response Circulation | Clinic |
| 29391879 | Furthermore, acupuncture combined with drugs can effectively suppress the central nervous system, improve microcirculation and oxygen metabolism of brain tissues, increase cerebral blood supply, relieve cerebral edema, and reduce inflammatory responses in the hippocampus caused by inflammatory factors crossing the blood-brain barrier. | Oncol Lett. 2018 Jan;15(1):189-194. doi: 10.3892/ol.2017.7262. Epub 2017 Oct 24. | Microcirculation | Clinic |
| 22611431 | In animal studies, electroacupuncture at the Neiguan (PC-6) and Jianshi (PC-5) points affects the circulatory and sympathetic nervous system, especially electroacupuncture at the PC-6 point increases haemodynamics and makes bleeding-induced hypotension less severe. | Evid Based Complement Alternat Med. 2012;2012:727121. doi: 10.1155/2012/727121. Epub 2012 Jan 31. | Bleeding Circulation | Clinic |
| 23573118 | According to a well-known part of classical Chinese medical theoryxe2x80x94the Shang Han Lunxe2x80x94which is systematized in the xe2x80x9cAlgor Laedens Theoryxe2x80x9d of the xe2x80x9cHeidelberg model of TCMxe2x80x9d, severe postoperative pain arises from xe2x80x9cxue stasisxe2x80x9d (relative hypoxis of a tissue arising from a disrupted microcirculation) due to xe2x80x9cpost-traumatic algorxe2x80x9d (reduced microcirculation of a tissue following a trauma due to vasospasmic reflexes and immunological reactions). | Evid Based Complement Alternat Med. 2013;2013:219817. doi: 10.1155/2013/219817. Epub 2013 Mar 14. | Immunity Microcirculation | Clinic |
| 15937559 | Some patients had transitory circulatory complications. | Evid Based Complement Alternat Med. 2005 Jun;2(2):185-189. doi: 10.1093/ecam/neh097. Epub 2005 May 11. | Circulation | Clinic |
| 30425466 | The bloodxe2x80x93brain barrier (BBB) is a multicellular vascular structure that separates the central nervous system (CNS) from the peripheral blood circulation. | Clin Interv Aging. 2018 Oct 24;13:2127-2134. doi: 10.2147/CIA.S183698. eCollection 2018. | Circulation | Clinic |
| 30425466 | Intraoperative circulatory system was maintained by adjusting the anesthesia depth (controlling BIS, 40xe2x80x9360) and administering transfusions or cardiovascular agents as necessary. | Clin Interv Aging. 2018 Oct 24;13:2127-2134. doi: 10.2147/CIA.S183698. eCollection 2018. | Cardiovascular Circulation | Clinic |
| 22337865 | Both low-frequency electro-acupuncture (EA) and manual acupuncture improve menstrual frequency and decrease circulating androgens in women with polycystic ovary syndrome (PCOS). | Exp Physiol. 2012 May;97(5):651-62. doi: 10.1113/expphysiol.2011.063131. Epub 2012 Feb 15. | Circulation | Mechanism |
| 16224585 | We studied the effect of acupuncture analgesia on the expression of ppENKmRNA, MEK-IR, and Dyn-IR in circulating mouse lymphocytes. | Bull Exp Biol Med. 2005 Jun;139(6):698-9. doi: 10.1007/s10517-005-0382-3. | Circulation | Mechanism |
| 25185370 | Effect of zusanli (ST 36) moxibustion on rat mesenteric microvascular system. | J Tradit Chin Med. 2014 Aug;34(4):491-7. doi: 10.1016/s0254-6272(15)30052-2. | Microcirculation | Mechanism |
| 25185370 | OBJECTIVE: To investigate the effect of moxibustion on Zusanli (ST 36) on visceral-mesenteric vessels by observing circulation. | J Tradit Chin Med. 2014 Aug;34(4):491-7. doi: 10.1016/s0254-6272(15)30052-2. | Circulation | Mechanism |
| 25185370 | We continuously monitored mesenteric microvascular changes with in vivo microscopic video. | J Tradit Chin Med. 2014 Aug;34(4):491-7. doi: 10.1016/s0254-6272(15)30052-2. | Microcirculation | Mechanism |
| 22884518 | The blood and lymphatic systems are the two well-established circulatory systems. | Cytokine. 2012 Nov;60(2):587-92. doi: 10.1016/j.cyto.2012.07.016. Epub 2012 Aug 10. | Circulation | Mechanism |
| 22884518 | The existence of a third circulatory system representing acupuncture meridians was claimed in the 1960s. | Cytokine. 2012 Nov;60(2):587-92. doi: 10.1016/j.cyto.2012.07.016. Epub 2012 Aug 10. | Circulation | Mechanism |
| 22884518 | Our results reveal a potential circulatory system whose anatomical structure and cellular content differ from the blood and lymph systems, and which may be involved in the transport of secretory granules. | Cytokine. 2012 Nov;60(2):587-92. doi: 10.1016/j.cyto.2012.07.016. Epub 2012 Aug 10. | Circulation | Mechanism |
| 2469996 | The circulatory border was estimated before and after treatment. | Neurosci Lett. 1989 Feb 27;97(3):305-9. doi: 10.1016/0304-3940(89)90615-0. | Circulation | Mechanism |
| 2469996 | It was shown that treatment with EA increased the blood flow moving the circulatory border distally 66% after a treatment. | Neurosci Lett. 1989 Feb 27;97(3):305-9. doi: 10.1016/0304-3940(89)90615-0. | Circulation Blood Flow | Mechanism |
| 2469996 | Injection of NaCl into the dorsal central vein of the flap resulted in no increase in blood flow whereas SP 10(-9) M and CGRP 10(-9) M increased the blood flow so that the circulatory border moved distally 31% and 49%, respectively. | Neurosci Lett. 1989 Feb 27;97(3):305-9. doi: 10.1016/0304-3940(89)90615-0. | Circulation Blood Flow | Mechanism |
| 19151301 | BACKGROUND: Acupuncture stimulation and phototherapy have been reported to have analgesic effects and improve the microcirculation. | Anesth Analg. 2009 Feb;108(2):635-40. doi: 10.1213/ane.0b013e31819317bc. | Analgesic Effect Microcirculation | Mechanism |
| 19151301 | Acupuncture stimulation and phototherapy, associated with minimal systemic and local side effects, can enhance the microcirculation and may be a useful supportive treatment for diseases caused by poor peripheral blood flow. | Anesth Analg. 2009 Feb;108(2):635-40. doi: 10.1213/ane.0b013e31819317bc. | Microcirculation Side Effects Blood Flow | Mechanism |
| 2883836 | Effects of acupuncture needle application upon cutaneous microcirculation of rabbit ear lobe. | Acupunct Electrother Res. 1987;12(1):45-51. doi: 10.3727/036012987816951121. | Microcirculation | Mechanism |
| 2883836 | Although no striking findings were obtained during the needle application for a period of 30 minutes, it was clearly observed that the microvascular blood flow increases gradually in parallel with augmenting spontaneous rhythmic fluctuation of the vessel diameter, namely vasomotion, throughout a continuous observation period longer than 2 hours following release from the needle application. | Acupunct Electrother Res. 1987;12(1):45-51. doi: 10.3727/036012987816951121. | Microcirculation Blood Flow | Mechanism |
| 2883836 | The clinical efficacy of acupuncture was suggested to be explained at least in part by the increased rhythmic microvascular blood flow in parallel with vasomotion, from the physiological point of view based on the previous investigations. | Acupunct Electrother Res. 1987;12(1):45-51. doi: 10.3727/036012987816951121. | Microcirculation Blood Flow | Mechanism |
| 24474333 | The results indicated that acupuncture has a synergistic effect on the pharmacokinetics and tissue distribution of the three lignans, which could postpone their elimination, resulting in a longer blood circulating time in rat plasma and prolonged residence time in target tissues, leading to higher tissue concentration. | Biomed Chromatogr. 2014 Aug;28(8):1075-83. doi: 10.1002/bmc.3122. Epub 2014 Jan 29. | Circulation | Mechanism |
| 20546685 | Recent data have also shown that angiogenesis indeed brings benefit to cerebral circulation and behavior improvement. | Neurol Res. 2011 Jan;33(1):101-7. doi: 10.1179/016164110X12714125204317. Epub 2010 Jun 11. | Circulation | Mechanism |
| 23386059 | Finally, EA effect on peripheral and adrenal SNS hormones (norepinephrine (NE) and neuropeptide Y (NPY) respectively) was examined, with no significant difference noted in adrenal tyrosine hydroxylase or circulating NE in any of the groups. | J Endocrinol. 2013 Mar 15;217(1):95-104. doi: 10.1530/JOE-12-0404. Print 2013 Apr. | Circulation | Mechanism |
| 20813156 | EA stimulation could increase local blood circulation and improve motor function in HIBD rats. | Neurosci Lett. 2010 Nov 12;485(1):74-8. doi: 10.1016/j.neulet.2010.08.068. Epub 2010 Sep 9. | Circulation Motor Function | Mechanism |
| 24170631 | Indices of neurobehavioral scores, cerebral blood flow, infarction rate, microcirculation, and light microscope, etc. | Chin J Integr Med. 2013 Nov;19(11):853-8. doi: 10.1007/s11655-013-1530-7. Epub 2013 Oct 30. | Microcirculation Blood Flow | Mechanism |
| 25963796 | Circulating gonadotropins and ovarian adiponectin system are modulated by acupuncture independently of sex steroid or beta-adrenergic action in a female hyperandrogenic rat model of polycystic ovary syndrome. | Mol Cell Endocrinol. 2015 Sep 5;412:159-69. doi: 10.1016/j.mce.2015.04.026. Epub 2015 May 8. | Circulation | Mechanism |
| 25963796 | Low-frequency EA induced estrous-cycle changes, decreased high levels of circulating luteinizing hormone (LH) and the LH/follicle-stimulating hormone (FSH) ratio, decreased high ovarian gene expression of adiponectin receptor 2, and increased expression of adiponectin receptor 2 protein and phosphorylation of ERK1/2. | Mol Cell Endocrinol. 2015 Sep 5;412:159-69. doi: 10.1016/j.mce.2015.04.026. Epub 2015 May 8. | Circulation | Mechanism |
| 25963796 | Estradiol decreased circulating LH, induced estrous cycle changes, and decreased ovarian expression of Adipor1, Foxo3, and Pik3r1. | Mol Cell Endocrinol. 2015 Sep 5;412:159-69. doi: 10.1016/j.mce.2015.04.026. Epub 2015 May 8. | Circulation | Mechanism |
| 25963796 | Thus, EA modulates the circulating gonadotropin levels independently of sex steroids or beta-adrenergic action and affects the expression of ovarian adiponectin system. | Mol Cell Endocrinol. 2015 Sep 5;412:159-69. doi: 10.1016/j.mce.2015.04.026. Epub 2015 May 8. | Circulation | Mechanism |
| 24619238 | Neurobehavioral scores, cerebral blood flow, infarction rate, microcirculation, light microscopy, etc. | Chin J Integr Med. 2014 Feb;20(2):130-5. doi: 10.1007/s11655-013-1584-6. Epub 2014 Mar 6. | Microcirculation Blood Flow | Mechanism |
| 28483183 | Therefore, the application of low-frequency TENS at the thoracolumbar sympathetic ganglions was more effective in increasing peripheral blood circulation than stimulation at acupuncture points. | J Acupunct Meridian Stud. 2017 Apr;10(2):120-124. doi: 10.1016/j.jams.2017.01.003. Epub 2017 Jan 12. | Circulation | Mechanism |
| 635615 | Possible mechanisms to explain alleged acupuncture-induced arousal may include vasodilatory effects caused by smypathetic stimulation which leads to an augmentation of cerebral microcirculation and thereby improves oxygen supply to the brain tissue. | South Med J. 1978 Apr;71(4):392-5, 398. doi: 10.1097/00007611-197804000-00015. | Microcirculation | Mechanism |
| 34553631 | BACKGROUND: A hyperdynamic circulation and impaired vascular responsiveness to vasoconstrictors are observed in portal hypertension (PHT) rats. | Acupunct Med. 2022 Feb;40(1):68-77. doi: 10.1177/09645284211039230. Epub 2021 Sep 23. | Circulation | Mechanism |
| 34553631 | Inflammation is a major contributor to the hyperdynamic circulation state in murine models of PHT. | Acupunct Med. 2022 Feb;40(1):68-77. doi: 10.1177/09645284211039230. Epub 2021 Sep 23. | Circulation | Mechanism |
| 27790765 | All treatments increased circulating levels of low-density lipoprotein-cholesterol. | Exp Physiol. 2017 Jan 1;102(1):113-127. doi: 10.1113/EP085983. | Circulation | Mechanism |
| 608334 | Possible mechanisms to explain alleged acupuncture-induced arousal may include vasodilatory effects caused by sympathetic stimulation which leads to an augmentation of cerebral microcirculation and thereby improves oxygen supply to the brain tissue. | Comp Med East West. 1977 Summer;5(2):147-54. doi: 10.1142/s0147291777000210. | Microcirculation | Mechanism |
| 35216533 | Here, the efficacy of electroacupuncture (EA) with respect to regulation of microvascular remodeling induced by VEGF/PI3K/Akt was evaluated in a rat model of COPD. | Acupunct Med. 2022 Aug;40(4):389-400. doi: 10.1177/09645284221078873. Epub 2022 Feb 25. | Microcirculation | Mechanism |
| 484537 | Cross circulation was performed between the femoral arteries and veins of paired rabbits that were entirely conscious. | Am J Chin Med. 1979 Summer;7(2):143-8. doi: 10.1142/s0192415x79000118. | Circulation | Mechanism |
| 34562596 | Adiponectin regulates electroacupuncture-produced analgesic effects in association with a crosstalk between the peripheral circulation and the spinal cord. | Brain Behav Immun. 2022 Jan;99:43-52. doi: 10.1016/j.bbi.2021.09.010. Epub 2021 Sep 22. | Analgesic Effect Circulation | Mechanism |
| 34562596 | Adiponectin (APN), a circulating adipokine, shows analgesic effects. | Brain Behav Immun. 2022 Jan;99:43-52. doi: 10.1016/j.bbi.2021.09.010. Epub 2021 Sep 22. | Analgesic Effect Circulation | Mechanism |
| 34562596 | The immunofluorescence staining analysis showed that EA increased the APN accumulation in spinal cord through the blood circulation. | Brain Behav Immun. 2022 Jan;99:43-52. doi: 10.1016/j.bbi.2021.09.010. Epub 2021 Sep 22. | Immunity Circulation | Mechanism |
| 33360522 | After that, immunocytochemical and immunofluorescence staining was used to quantify the angiogenesis and compensatory circulation, which including the analysis of microvessel density, field/ microvessel area ratio, and microvessel diameter. | J Stroke Cerebrovasc Dis. 2021 Mar;30(3):105165. doi: 10.1016/j.jstrokecerebrovasdis.2020.105165. Epub 2020 Dec 24. | Immunity Circulation | Mechanism |
| 17322780 | The first formula was chosen to expel wind and dampness, enhance kidney and liver energy, help Qi/Xue circulation and alleviate pain. | J Vet Sci. 2007 Mar;8(1):95-8. doi: 10.4142/jvs.2007.8.1.95. | Kidney Circulation | Mechanism |
| 30883553 | Moreover, the modulation of the immune system and microcirculation are also considered important effects in acupoint activation and acupuncture mechanisms. | PLoS One. 2019 Mar 18;14(3):e0211341. doi: 10.1371/journal.pone.0211341. eCollection 2019. | Immunity Microcirculation | Mechanism |
| 30883553 | Previous results indicated the mean blood flow was larger at the acupoints than in their surrounding tissues, indicating when an acupoint was stimulated adequately, the blood perfusion of this point continued to increase and improve local microcirculation in specific organs and tissues. | PLoS One. 2019 Mar 18;14(3):e0211341. doi: 10.1371/journal.pone.0211341. eCollection 2019. | Microcirculation Blood Flow | Mechanism |
| 30883553 | The immune cells, mast cells, may play a crucial role in mediating the establishment of networks among the circulatory, nervous and immune system at the acupoints. | PLoS One. 2019 Mar 18;14(3):e0211341. doi: 10.1371/journal.pone.0211341. eCollection 2019. | Immunity Circulation | Mechanism |
| 30883553 | This is probably because LA can promote local microcirculation to increase waste removal and adequate nutrient delivery to chondrocytes. | PLoS One. 2019 Mar 18;14(3):e0211341. doi: 10.1371/journal.pone.0211341. eCollection 2019. | Microcirculation | Mechanism |
| 25139460 | The first-line treatments for patients with endotoxic shock, such as antibiotics, source control, and resuscitation with intravenous fluids to optimize circulation and organ perfusion, are largely limited to persistent hypo-perfusion and end-organ dysfunctions. | Med Sci Monit. 2014 Aug 16;20:1452-60. doi: 10.12659/MSM.890736. | Toxic Side Effects Circulation | Mechanism |
| 32761882 | Animals were placed in a black circular and 160 cm diameter pool (depth 40 cm) which was filled with water at 23 ± 1°C. | Brain Behav. 2020 Oct;10(10):e01781. doi: 10.1002/brb3.1781. Epub 2020 Aug 6. | Circulation | Mechanism |
| 32761882 | In these studies, manipulation strengthened the effect of acupuncture in changing skin temperature, increasing the blood circulation, exciting the sympathetic nerves, and promoting metabolism of the tissues. | Brain Behav. 2020 Oct;10(10):e01781. doi: 10.1002/brb3.1781. Epub 2020 Aug 6. | Skin Temperature Circulation | Mechanism |
| 25282142 | However, the self-regulation effects of acupuncture from these acupoints on the healthy body, which is an ongoing maintenance of balance and harmony in the circulation of Qi, are not known. | BMC Complement Altern Med. 2014 Oct 5;14:375. doi: 10.1186/1472-6882-14-375. | Circulation | Mechanism |
| 30740905 | We proposed that acupoint sensitization may not be associated with the structural changes in microcirculation and that the microcirculatory changes during acupoint sensitization are more likely to be functional. | J Biophotonics. 2019 Jun;12(6):e201800458. doi: 10.1002/jbio.201800458. Epub 2019 Mar 6. | Microcirculation | Mechanism |
| 30740905 | Therefore, the structural changes and functional characteristics of microcirculation during acupoint sensitization need to be clarified to improve diagnostic and treatment capabilities, as well as better understand of acupoint connotation. | J Biophotonics. 2019 Jun;12(6):e201800458. doi: 10.1002/jbio.201800458. Epub 2019 Mar 6. | Microcirculation | Mechanism |
| 30740905 | Microcirculation plays a pivotal role in metabolic supply and metabolism, regulating blood flow and maintaining homeostasis. | J Biophotonics. 2019 Jun;12(6):e201800458. doi: 10.1002/jbio.201800458. Epub 2019 Mar 6. | Microcirculation Blood Flow | Mechanism |
| 30740905 | Local microcirculation has been identified as an important target of acupuncture and is closely associated with the acupuncture effects 11. | J Biophotonics. 2019 Jun;12(6):e201800458. doi: 10.1002/jbio.201800458. Epub 2019 Mar 6. | Microcirculation | Mechanism |
| 30740905 | However, the structural and functional characteristics of microcirculation during the sensitization have been neglected to some extent. | J Biophotonics. 2019 Jun;12(6):e201800458. doi: 10.1002/jbio.201800458. Epub 2019 Mar 6. | Microcirculation | Mechanism |
| 30740905 | In the present study, we aimed to characterize the structural changes in microcirculation at several acupoints such as Yanglingquan (GB34) and Zusanli (ST36) by using PAI. | J Biophotonics. 2019 Jun;12(6):e201800458. doi: 10.1002/jbio.201800458. Epub 2019 Mar 6. | Microcirculation | Mechanism |
| 30740905 | Our findings can be added to the debate on the microcirculatory characteristics of sensitized acupoints and support the negative structural changes in microcirculation during acupoint sensitization. | J Biophotonics. 2019 Jun;12(6):e201800458. doi: 10.1002/jbio.201800458. Epub 2019 Mar 6. | Microcirculation | Mechanism |
| 30740905 | Quantitative analysis of microvascular morphological parameters | J Biophotonics. 2019 Jun;12(6):e201800458. doi: 10.1002/jbio.201800458. Epub 2019 Mar 6. | Microcirculation | Mechanism |
| 30740905 | A dedicated microvascular quantification algorithm, as described previously 20, 28, was used to quantitatively analyze the changes in microcirculatory structure at the GB34, ST36 and nonacupoint sites. | J Biophotonics. 2019 Jun;12(6):e201800458. doi: 10.1002/jbio.201800458. Epub 2019 Mar 6. | Microcirculation | Mechanism |
| 30740905 | No significant differences in the microvascular changes of the GB34, ST36 and nonacupoint sites were found on days 0, 7 and 21 among the N, NS and OA groups. | J Biophotonics. 2019 Jun;12(6):e201800458. doi: 10.1002/jbio.201800458. Epub 2019 Mar 6. | Microcirculation | Mechanism |
| 30740905 | These two acupoints were selected as the target acupoints in this study to better clarify the structural changes of microcirculation during acupoint sensitization. | J Biophotonics. 2019 Jun;12(6):e201800458. doi: 10.1002/jbio.201800458. Epub 2019 Mar 6. | Microcirculation | Mechanism |
| 30740905 | Based on these findings, we hypothesized that acupoint sensitization primarily contribute to the functional changes in microcirculation. | J Biophotonics. 2019 Jun;12(6):e201800458. doi: 10.1002/jbio.201800458. Epub 2019 Mar 6. | Microcirculation | Mechanism |
| 30740905 | Moreover, it was speculated that the acupoint sensitization on microcirculation is more likely to be functional and thus displays a functional characteristic. | J Biophotonics. 2019 Jun;12(6):e201800458. doi: 10.1002/jbio.201800458. Epub 2019 Mar 6. | Microcirculation | Mechanism |
| 30740905 | The functional changes in the microcirculation during acupoint sensitization such as hemoglobin oxygen saturation, blood flow and rate of oxygen metabolism should be investigated. | J Biophotonics. 2019 Jun;12(6):e201800458. doi: 10.1002/jbio.201800458. Epub 2019 Mar 6. | Microcirculation Blood Flow | Mechanism |
| 30740905 | To the best of our knowledge, this study is the first time that acupoint sensitization in knee OA has been shown to have no association with the structural changes in microcirculation, suggesting that microcirculatory changes during acupoint sensitization are more likely to be functional. | J Biophotonics. 2019 Jun;12(6):e201800458. doi: 10.1002/jbio.201800458. Epub 2019 Mar 6. | Microcirculation | Mechanism |
| 30740905 | It is suggested that the structural changes in microcirculation lag behind functional changes and are closely associated with disease severity. | J Biophotonics. 2019 Jun;12(6):e201800458. doi: 10.1002/jbio.201800458. Epub 2019 Mar 6. | Microcirculation | Mechanism |
| 30740905 | In an experimental knee OA mouse model, structural changes in the microcirculation were dynamically observed during acupoint sensitization. | J Biophotonics. 2019 Jun;12(6):e201800458. doi: 10.1002/jbio.201800458. Epub 2019 Mar 6. | Microcirculation | Mechanism |
| 30740905 | This study preliminarily confirmed that acupoint sensitization in knee OA is not associated with structural changes in microcirculation at the ST36, GB34 and nonacupoints sites. | J Biophotonics. 2019 Jun;12(6):e201800458. doi: 10.1002/jbio.201800458. Epub 2019 Mar 6. | Microcirculation | Mechanism |
| 30740905 | Further research should focus on the functional changes in the microcirculation during acupoint sensitization such as hemoglobin oxygen saturation, blood flow and rate of oxygen metabolism. | J Biophotonics. 2019 Jun;12(6):e201800458. doi: 10.1002/jbio.201800458. Epub 2019 Mar 6. | Microcirculation Blood Flow | Mechanism |
| 37435647 | Studies have shown that CRH secreted by neurons of the PVN small-cell population activated the HPA axis, which released ACTH into circulation through the portal system. | J Neurophysiol. 2023 Aug 1;130(2):380-391. doi: 10.1152/jn.00156.2023. Epub 2023 Jul 12. | Circulation | Mechanism |
| 24828425 | The BBB facilitates selective, diffusion-mediated exchange of membrane-permeant molecules between the circulating blood and the central nervous system, and in this manner protects the brain from extraneous compounds and neurotoxic substances. | PLoS One. 2014 May 14;9(5):e97488. doi: 10.1371/journal.pone.0097488. eCollection 2014. | Toxic Side Effects Circulation | Mechanism |
| 35704659 | Ghrelin, an orexigenic hormone, is mainly produced by stomach and released to circulation. | PLoS One. 2022 Jun 15;17(6):e0259609. doi: 10.1371/journal.pone.0259609. eCollection 2022. | Circulation | Mechanism |
| 35704659 | Levels of circulating GAL during puberty have been discovered to be significantly higher than those in pre-puberty in patients with type 1 diabetes mellitus, while levels of ghrelin were significantly lower. | PLoS One. 2022 Jun 15;17(6):e0259609. doi: 10.1371/journal.pone.0259609. eCollection 2022. | Circulation | Mechanism |
| 23349861 | Because the sample volume was limited, we could not measure circulating glucagon. | PLoS One. 2013;8(1):e54357. doi: 10.1371/journal.pone.0054357. Epub 2013 Jan 18. | Circulation | Mechanism |
| 21796340 | A second cell model was murine microvascular endothelial cell line H5V. | Pflugers Arch. 2011 Oct;462(4):587-97. doi: 10.1007/s00424-011-0993-7. Epub 2011 Jul 28. | Microcirculation | Mechanism |
| 29123119 | CGRP released by activation of small fibre sensory nerve terminals causes neurogenic inflammation in the skin by activating vasodilation, axon reflex flare, and microvascular plasma extravasation. | Sci Rep. 2017 Nov 9;7(1):15214. doi: 10.1038/s41598-017-14359-z. | Microcirculation | Mechanism |
| 24722278 | Past records indicate that needling at Neiguan (PC6) acupoint exerts cardioprotective effects on several kinds of ischemic heart injuries, including cardiac surgery, myocardial ischemia-reperfusion, and acute myocardial ischemia by improving hemodynamics, microcirculation and energy metabolism, as well as decreasing susceptibility to ventricular tachycardia. | PLoS One. 2014 Apr 10;9(4):e94604. doi: 10.1371/journal.pone.0094604. eCollection 2014. | Microcirculation Hemodynamics | Mechanism |
| 24722278 | Circulating endothelial progenitor cells (cEPCs) were identified by CD34 antibody, smooth muscle cells were identified by α-SMA, and endothelial cells were identified by VEGF. | PLoS One. 2014 Apr 10;9(4):e94604. doi: 10.1371/journal.pone.0094604. eCollection 2014. | Circulation | Mechanism |
| 24722278 | CD34-, α-SMA- and VEGF- positive cells were presented to the circulating endothelial progenitor cells (cEPCs), vascular smooth muscle cells, and endothelial cells, respectively. | PLoS One. 2014 Apr 10;9(4):e94604. doi: 10.1371/journal.pone.0094604. eCollection 2014. | Circulation | Mechanism |
| 24908398 | Our results showed that, in the N and S groups, DOG1-like immunoreactivity (DOG1-LI) was localized in two distinct populations of ICC, one population with processes and numerous branches forming a cellular network between the circular and longitudinal muscle layers at the level of the myenteric plexus (ICC-MY), and a second population at the level of the deep muscular plexus in the circular muscle layer (ICC-DMP). | BMC Complement Altern Med. 2014 Jun 7;14:186. doi: 10.1186/1472-6882-14-186. | Immunity Circulation | Mechanism |
| 24886495 | This point is associated with more than ten common diseases, including digestive, respiratory, circulatory, urinary and nervous disorders. | BMC Complement Altern Med. 2014 May 31;14:178. doi: 10.1186/1472-6882-14-178. | Gastrointestinal Tract Circulation | Mechanism |
| 32249904 | It functions by unclogging meridians, regulating blood circulation, which results in strengthening the immunity system, and preventing and/or treating diseases. | Biosci Rep. 2020 May 29;40(5):BSR20191517. doi: 10.1042/BSR20191517. | Immunity Circulation | Mechanism |
| 32249904 | Through integration of the acupuncture and warm effects, and specific responses to acupoint stimulation, Mongolian medical warm acupuncture can treat diseases by regulating multiple aspects of function various body parts, which involves multi-pathway mechanisms and the function of the blood circulatory system, the nervous system and the immune system. | Biosci Rep. 2020 May 29;40(5):BSR20191517. doi: 10.1042/BSR20191517. | Immunity Circulation | Mechanism |
| 32249904 | It functions by unclogging meridians, regulating blood circulation, which results in strengthening the immunity system, and preventing and/or treating diseases. | Biosci Rep. 2020 May 29;40(5):BSR20191517. doi: 10.1042/BSR20191517. | Immunity Circulation | Mechanism |
| 15046638 | How systemic circulatory changes affect OBF was evaluated by continuous recording of the blood pressure. | Reprod Biol Endocrinol. 2004 Mar 26;2:16. doi: 10.1186/1477-7827-2-16. | Blood Pressure Circulation | Mechanism |
| 15046638 | In addition, the contribution of systemic circulatory changes to OBF was evaluated by continuous recording of the blood pressure. | Reprod Biol Endocrinol. 2004 Mar 26;2:16. doi: 10.1186/1477-7827-2-16. | Blood Pressure Circulation | Mechanism |
| 15046638 | These results further indicate that OBF in PCO rats is resistant to systemic circulatory changes. | Reprod Biol Endocrinol. 2004 Mar 26;2:16. doi: 10.1186/1477-7827-2-16. | Circulation | Mechanism |
| 28358020 | reported a positive correlation between circulating EGF level and LDL levels. | Sci Rep. 2017 Mar 30;7:45580. doi: 10.1038/srep45580. | Circulation | Mechanism |
| 23323213 | If the source is the blood vessel, is there still sufficient FDG circulating in the blood vessel for uptake at the one hour time point after the FDG injection, given that the metabolism of rat is much faster than that of human? | Sci Rep. 2013;3:1070. doi: 10.1038/srep01070. Epub 2013 Jan 15. | Circulation | Mechanism |
| 23323213 | One hypothesis is that the local alternative circulation system (e.g., the capillary network) is transporting FDG to the brain tissues. | Sci Rep. 2013;3:1070. doi: 10.1038/srep01070. Epub 2013 Jan 15. | Circulation | Mechanism |
| 29981376 | In models of inflammation, stimulation of ST36 or other acupoints (e.g., Huantiao GB30 and Yanglingquan GB34) reduces the activation of glial cells in spinal tissues, the activation of macrophages and T cells in peripheral tissues and the production of pro-inflammatory cytokines in circulating blood. | J Pain. 2018 Dec;19(12):1384.e1-1384.e14. doi: 10.1016/j.jpain.2018.05.013. Epub 2018 Jul 4. | Circulation | Mechanism |
| 29981376 | Furthermore, acupuncture induces the local release of endogenous opioids (e.g., β-endorphin) and cannabinoids (e.g., anandamide) that act on peripheral nerve terminals to suppress the transduction of pain and on immune cells to decrease the production of pro-inflammatory cytokines in circulation. | J Pain. 2018 Dec;19(12):1384.e1-1384.e14. doi: 10.1016/j.jpain.2018.05.013. Epub 2018 Jul 4. | Immunity Circulation | Mechanism |
| 32956833 | Due in part to its broad anatomical distribution, the SP/NK1R system is involved in a variety of complex physiological responses, including neuroinflammation, microvascular permeability, and pain. | Brain Behav Immun. 2021 Jan;91:683-694. doi: 10.1016/j.bbi.2020.08.016. Epub 2020 Sep 18. | Microcirculation | Mechanism |
| 32956833 | These neuropeptides play a role in neurogenic inflammation in the skin by activating vasodilation, axon reflex flare, and microvascular plasma extravasation. | Brain Behav Immun. 2021 Jan;91:683-694. doi: 10.1016/j.bbi.2020.08.016. Epub 2020 Sep 18. | Microcirculation | Mechanism |
| 27179524 | Effect of Electroacupuncture on Perinatal Nicotine-Induced Changes in Circulating β-endorphin Levels | Lung. 2016 Aug;194(4):535-46. doi: 10.1007/s00408-016-9899-7. Epub 2016 May 14. | Circulation | Mechanism |
| 27179524 | Effect of electro-acupuncture on perinatal nicotine-induced changes in circulating β-endorphin levels | Lung. 2016 Aug;194(4):535-46. doi: 10.1007/s00408-016-9899-7. Epub 2016 May 14. | Circulation | Mechanism |
| 31600836 | Those regions excluded contain small nuclei in the thalamus, hypothalamus, and midbrain, as well as minor commissural or tract nuclei such as the precommissural nucleus, scaphoid nucleus, circular nucleus, stigmoid nucleus, premammillary nucleus, and the fields of Forel, among others. | J Comp Neurol. 2020 Apr;528(6):953-971. doi: 10.1002/cne.24789. Epub 2019 Nov 12. | Circulation | Mechanism |
| 38026466 | In the future, it will be necessary to test the therapeutic effect of IQAB using a larger sample size, different CSR stages, and detection indicators that better reflect the state of Qi and Blood such as microcirculation and motor scores. | J Pain Res. 2023 Nov 20;16:3945-3960. doi: 10.2147/JPR.S419927. eCollection 2023. | Microcirculation | Mechanism |
| 36816326 | Relative to rats in the Gs group, those in the Gi group exhibited reductions in circulating and splenic Treg cells, whereas this trend was reversed for rats in the Ga group, although these differences were not significant (PÂ >Â 0.05). | Heliyon. 2023 Jan 31;9(2):e13346. doi: 10.1016/j.heliyon.2023.e13346. eCollection 2023 Feb. | Circulation | Mechanism |
| 36536227 | Generally, placing needles in acupuncture points is thought to not only enhance blood circulation but also stimulate the nervous systems and increase the release of anti-inflammatory and pain substances. | Vet Res Commun. 2023 Jun;47(2):879-884. doi: 10.1007/s11259-022-10051-4. Epub 2022 Dec 19. | Circulation Inflammatory Pain | Mechanism |
| 23304201 | Acupuncture regulates inflammation process and growth factors by increasing blood circulation in affected areas. | Evid Based Complement Alternat Med. 2012;2012:464586. doi: 10.1155/2012/464586. Epub 2012 Dec 10. | Circulation | Mechanism |
| 23304201 | Furthermore, acupuncture attenuates inflammation increasing blood circulation at the affected area. | Evid Based Complement Alternat Med. 2012;2012:464586. doi: 10.1155/2012/464586. Epub 2012 Dec 10. | Circulation | Mechanism |
| 25206406 | The far-end of the internal carotid artery was blocked with a microvascular clip. | Neural Regen Res. 2013 Apr 25;8(12):1122-31. doi: 10.3969/j.issn.1673-5374.2013.12.007. | Microcirculation | Mechanism |
| 25206406 | The silk suture around the internal carotid artery was tightened and the microvascular clip was removed. | Neural Regen Res. 2013 Apr 25;8(12):1122-31. doi: 10.3969/j.issn.1673-5374.2013.12.007. | Microcirculation | Mechanism |
| 34630618 | Consequently, the synthesis, metabolism, and detoxification functions of the liver would be hampered and excessive ammonia and endotoxin that cannot be neutralized by the liver would enter blood circulation. | Evid Based Complement Alternat Med. 2021 Oct 1;2021:7992688. doi: 10.1155/2021/7992688. eCollection 2021. | Circulation | Mechanism |
| 34630618 | On the other hand, inflammatory cytokines released after NF-κB activation can enter the peripheral blood circulation to aggravate infection and induce systemic inflammatory response, thereby playing an important role during pathogenesis and progression of HE synergistically with hyperammonemia. | Evid Based Complement Alternat Med. 2021 Oct 1;2021:7992688. doi: 10.1155/2021/7992688. eCollection 2021. | Circulation | Mechanism |
| 31447579 | Circulating SP levels are elevated in patients with SCD. | J Pain Res. 2019 Aug 1;12:2419-2426. doi: 10.2147/JPR.S210196. eCollection 2019. | Circulation | Mechanism |
| 31447579 | Therefore, it is likely that circulating SP in patients with SCD may be informative about its presence in the peripheral and central nervous system and may serve as a biomarker to predict response to EA analgesia. | J Pain Res. 2019 Aug 1;12:2419-2426. doi: 10.2147/JPR.S210196. eCollection 2019. | Circulation | Mechanism |
| 31217804 | These vasoconstrictive neurotransmitters are also important for regulating the peripheral and central circulation, leading to activation and sensitization of the trigeminovascular system (TS) (Figure 1(a)). | Evid Based Complement Alternat Med. 2019 May 14;2019:9512875. doi: 10.1155/2019/9512875. eCollection 2019. | Circulation | Mechanism |
| 24803946 | In addition to the damage at the site of the spinal cord injury, secondary pathological changes occur in the following order: edema, ischemia, calcium overload, lipid peroxidation, microcirculation obstruction, and apoptosis. | Evid Based Complement Alternat Med. 2014;2014:431580. doi: 10.1155/2014/431580. Epub 2014 Apr 3. | Microcirculation | Mechanism |
| 30136700 | The apparatus (Chengdu Taimeng Technology Co., Ltd., Chengdu, China) consisted of a large circular pool (120 cm in diameter, 50 cm in height) and a MT-200 Morris water maze video-tracking system (Chengdu Taimeng Technology Co., Ltd., Chengdu, China). | Neural Regen Res. 2018 Oct;13(10):1833-1841. doi: 10.4103/1673-5374.238620. | Circulation | Mechanism |
| 30136700 | The circular platform (10 cm in diameter) was placed at the midpoint of the target quadrant and submerged approximately 1.5 cm below the surface of the water. | Neural Regen Res. 2018 Oct;13(10):1833-1841. doi: 10.4103/1673-5374.238620. | Circulation | Mechanism |
| 28672928 | Mongolian medicine can improve sleep and treat insomnia by alleviating Heyi, circulating Heyi blood, and balancing Heyi, Xila, and Badagan. | Exp Ther Med. 2017 Jul;14(1):289-297. doi: 10.3892/etm.2017.4452. Epub 2017 May 11. | Insomnia Circulation | Mechanism |
| 28672928 | Mongolian medical warm acupuncture integrates acupuncture effect, hyperthermia, and acupoint specific stimulation and achieves organism regulation and disease treatment via the complex multi-system, multi-channel, and multi-path mechanism relevant to blood circulation, nervous system and immune function. | Exp Ther Med. 2017 Jul;14(1):289-297. doi: 10.3892/etm.2017.4452. Epub 2017 May 11. | Immunity Circulation | Mechanism |
| 25861363 | Researches have found that acupuncture can effectively improve the motor function of ischemic stroke patients, possibly due to the improvement of cerebral circulation, but the underlying biological mechanisms of acupuncture effects are still poorly understood and need to be further explored. | Evid Based Complement Alternat Med. 2015;2015:496932. doi: 10.1155/2015/496932. Epub 2015 Mar 10. | Circulation Motor Function | Mechanism |
| 23983780 | Thus, it is possible that PMCSs might be similar to microvesicles (MVs), small circular membrane fragments shed from the cell surface or released from the endosomal compartment. | Evid Based Complement Alternat Med. 2013;2013:438079. doi: 10.1155/2013/438079. Epub 2013 Jul 31. | Circulation | Mechanism |
| 28806763 | On the other hand, the down-regulated genes in the hypothalamus were also mainly located in extracellular region but were involved in the regulation of defense response to bacterium and blood circulation, and no significantly enriched pathway was detected. | PLoS One. 2017 Aug 14;12(8):e0181948. doi: 10.1371/journal.pone.0181948. eCollection 2017. | Circulation | Mechanism |
| 28299842 | Electro-acupuncture (EA) performed in rats and humans using front-limb acupuncture sites, LI-4 and LI-11, and Du-14 and Du-20 increased functional connectivity between the anterior hypothalamus and the amygdala and mobilized mesenchymal stem cells (MSC) into the systemic circulation. | Stem Cells. 2017 May;35(5):1303-1315. doi: 10.1002/stem.2613. | Circulation | Mechanism |
| 28299842 | Pharmacological disinhibition of rat hypothalamus enhanced sympathetic nervous system (SNS) activation and similarly resulted in a release of MSC into the circulation. | Stem Cells. 2017 May;35(5):1303-1315. doi: 10.1002/stem.2613. | Circulation | Mechanism |
| 28299842 | A 313% increase in the circulating mesenchymal stem cell (MSC) population, LinâCD90+CD44HI cells, was detected in the blood of EA-treated rats 2 h post-EA compared to baseline (Figure 3 A, B). | Stem Cells. 2017 May;35(5):1303-1315. doi: 10.1002/stem.2613. | Circulation | Mechanism |
| 28299842 | Because hypothalamic activation (Figure 1 B) preceded the mobilization of circulating MSC, it was proposed that the EA-induced connectivity changes contributed to the subsequent release of these cells into the peripheral blood. | Stem Cells. 2017 May;35(5):1303-1315. doi: 10.1002/stem.2613. | Circulation | Mechanism |
| 28299842 | Pharmacological disinhibition of the dorsomedial regions of the tuberal hypothalamus mobilizes LinâCD90HICD44+ cells into the circulation | Stem Cells. 2017 May;35(5):1303-1315. doi: 10.1002/stem.2613. | Circulation | Mechanism |
| 28299842 | In rats, BMI at the dose of 50 pmol increased the percentage of circulating LinâCD90HICD44+ cells (F (2, 14) =6.7, p=0.027) at 4 h post injection of BMI (Figure 4 E) in the absence of EA. | Stem Cells. 2017 May;35(5):1303-1315. doi: 10.1002/stem.2613. | Circulation | Mechanism |
| 28299842 | These results demonstrate that circulating LinâCD90HICD44+ cells are mobilized during hypothalamic disinhibition and EA. | Stem Cells. 2017 May;35(5):1303-1315. doi: 10.1002/stem.2613. | Circulation | Mechanism |
| 28299842 | To address the possible anti-inflammatory and analgesic effects of EA-mobilization of circulating MSC, we analyzed the contribution of an EA treatment paradigm on injury-induced hyperalgesia in rats in the presence and absence of a β-blocker, propranolol. | Stem Cells. 2017 May;35(5):1303-1315. doi: 10.1002/stem.2613. | Analgesic Effect Circulation | Mechanism |
| 28299842 | EA at immune points in the forelimbs preferentially mobilizes MSC whereas EA of immune points in the hind limb mobilizes macrophages into the circulation | Stem Cells. 2017 May;35(5):1303-1315. doi: 10.1002/stem.2613. | Immunity Circulation | Mechanism |
| 28299842 | However, due to the limited availability of equine MSC antibodies compared to humans and mice, stem cell mobilization into peripheral blood was confirmed by measuring circulating cell colony-forming ability in vitro. | Stem Cells. 2017 May;35(5):1303-1315. doi: 10.1002/stem.2613. | Circulation | Mechanism |
| 28299842 | This suggests either that the EA-mobilized MSC population may be derived from a source distinct from either adipose tissue or bone marrow, or that their mobilization into the systemic circulation modified their gene expression from that of the BM-MSC or ASC obtained directly from their tissue source. | Stem Cells. 2017 May;35(5):1303-1315. doi: 10.1002/stem.2613. | Circulation | Mechanism |
| 28299842 | Methods to mobilize circulating MSC (i.e. | Stem Cells. 2017 May;35(5):1303-1315. doi: 10.1002/stem.2613. | Circulation | Mechanism |
| 28299842 | EA-induced mobilization of circulating MSC may have served to directly or indirectly modulate anti-inflammatory and immunomodulatory properties in vivo, as we show by the increase in serum IL-10 levels and the observed reduced mechanical hyperalgesia. | Stem Cells. 2017 May;35(5):1303-1315. doi: 10.1002/stem.2613. | Immunity Circulation | Mechanism |
| 28299842 | EA may serve as a way to facilitate tissue repair following injury by supplying high levels of circulating MSC into the circulation and could be used to treat acute or chronic conditions associated with inflammation. | Stem Cells. 2017 May;35(5):1303-1315. doi: 10.1002/stem.2613. | Circulation | Mechanism |
| 28299842 | Circulating MSC were defined as Linâ(CD45âCD31âerythroidâCD11bâ) cells that were positive for CD44 and CD90. | Stem Cells. 2017 May;35(5):1303-1315. doi: 10.1002/stem.2613. | Circulation | Mechanism |
| 28299842 | D) The percentage of circulating MSCs from adipose tissue (AD-MSC) are significantly elevated in 2 h post EA-treatment (p=0.033, n=4). | Stem Cells. 2017 May;35(5):1303-1315. doi: 10.1002/stem.2613. | Circulation | Mechanism |
| 28299842 | EA-mediated sympathetic stimulation induces MSC release into the circulation | Stem Cells. 2017 May;35(5):1303-1315. doi: 10.1002/stem.2613. | Circulation | Mechanism |
| 32021397 | In this study, we observed increased IL-1β, IL-6, and TNF-α levels in the jugular vein blood, reflecting the inflammatory state of the intracranial circulation. | J Pain Res. 2020 Jan 13;13:75-86. doi: 10.2147/JPR.S225431. eCollection 2020. | Circulation | Mechanism |
| 19531626 | Changes of blood perfusion and microcirculation distribution in the stomach were investigated with laser Doppler blood perfusion imager (LDPI). | Evid Based Complement Alternat Med. 2011;2011:969231. doi: 10.1093/ecam/nep050. Epub 2010 Oct 20. | Microcirculation | Mechanism |
| 19531626 | It cannot only measure microcirculation of the skin but also measure general blood perfusion of the internal organs. | Evid Based Complement Alternat Med. 2011;2011:969231. doi: 10.1093/ecam/nep050. Epub 2010 Oct 20. | Microcirculation | Mechanism |
| 19531626 | In addition, the blood perfusion of microcirculation in other parts of the stomach increased in dissimilar degrees, it more obviously increased in the parts close to the moderate and small blood vessels. | Evid Based Complement Alternat Med. 2011;2011:969231. doi: 10.1093/ecam/nep050. Epub 2010 Oct 20. | Microcirculation | Mechanism |
| 19531626 | However, in the acupuncture or EA group, the blood perfusion in the moderate and small vessels and the micro-circulation increased simultaneously. | Evid Based Complement Alternat Med. 2011;2011:969231. doi: 10.1093/ecam/nep050. Epub 2010 Oct 20. | Circulation | Mechanism |
| 19531626 | The above actions of acupuncture and moxibustion are carried out possibly through improving gastric blood circulation, increasing nutrition, metabolism and anti-inflammatory substances in the lesion parts of the stomach. | Evid Based Complement Alternat Med. 2011;2011:969231. doi: 10.1093/ecam/nep050. Epub 2010 Oct 20. | Circulation | Mechanism |
| 19531626 | After acupuncture or EA, obviously a potent vasodilator reaction of gastric vessels was induced, with blood perfusion in the moderate and small vessels and microcirculation increased in dissimilar degrees, and this increase is the result offsetting the natural decrease of blood flow, so the action of acupuncture and EA increasing blood flow is obvious. | Evid Based Complement Alternat Med. 2011;2011:969231. doi: 10.1093/ecam/nep050. Epub 2010 Oct 20. | Microcirculation Blood Flow | Mechanism |
| 19531626 | After EA, the light green and yellow-red regions increased gradually, indicating that blood perfusion of the small vessels and microcirculation increased in dissimilar degrees. | Evid Based Complement Alternat Med. 2011;2011:969231. doi: 10.1093/ecam/nep050. Epub 2010 Oct 20. | Microcirculation | Mechanism |
| 29853959 | Angiotensin II (Ang II) is a key mediator in the development and the maintenance of hypertension which exerts effects on brain circulation by regulating vascular structures and two main mechanisms that control cerebral blood flow. | Evid Based Complement Alternat Med. 2018 Apr 26;2018:5712857. doi: 10.1155/2018/5712857. eCollection 2018. | Circulation Blood Flow | Mechanism |
| 26064171 | They have also pointed out a proven association between the primary mechanisms of the stimulatory effects of light and the secondary mechanisms defining the sanitation effects (bactericidal effect, cellular proliferation, and regulation of microcirculation). | Evid Based Complement Alternat Med. 2015;2015:687196. doi: 10.1155/2015/687196. Epub 2015 May 3. | Microcirculation | Mechanism |
| 25206545 | The ligatures (4-0 silk) were tied loosely around the nerve with 1 mm spacing, until they elicited a brief twitch in the respective hindlimb, but did not interrupt the epineurial circulation. | Neural Regen Res. 2013 Sep 5;8(25):2350-9. doi: 10.3969/j.issn.1673-5374.2013.25.006. | Circulation | Mechanism |
| 32082125 | A milky white, circular water pool (diameter of 120 cm, height of 50 cm, platform diameter of 10 cm, height of 22 cm) was filled to a depth of 20 cm with water kept at (25 ± 1°C). | Front Integr Neurosci. 2020 Jan 31;13:78. doi: 10.3389/fnint.2019.00078. eCollection 2019. | Circulation | Mechanism |
| 32082125 | It is considered to be the first cytokine present in the circulation during exercise and then initiates the cascade reaction of other cytokines and inflammatory factors. | Front Integr Neurosci. 2020 Jan 31;13:78. doi: 10.3389/fnint.2019.00078. eCollection 2019. | Circulation | Mechanism |
| 33328963 | The circulatory abnormalities are mainly attributed to the aging vasculature failing to cope with biological demands, which results in subcortical ischemia and white matter lesions. | Front Aging Neurosci. 2020 Nov 23;12:582904. doi: 10.3389/fnagi.2020.582904. eCollection 2020. | Circulation | Mechanism |
| 33328963 | The Morris Water Maze (MWM) consists of a circular pool 160 cm in diameter. | Front Aging Neurosci. 2020 Nov 23;12:582904. doi: 10.3389/fnagi.2020.582904. eCollection 2020. | Circulation | Mechanism |
| 33269744 | The water maze apparatus (Xin Ruan Information Technology, Shanghai, China) consists of a circular pool with a diameter of 150 cm and a height of 60 cm. | Neural Regen Res. 2021 Jun;16(6):1011-1016. doi: 10.4103/1673-5374.300454. | Circulation | Mechanism |
| 29623942 | This consists of three parts: a circular pool, a platform, and a recording system. | Neural Regen Res. 2018 Mar;13(3):541-548. doi: 10.4103/1673-5374.228760. | Circulation | Mechanism |
| 29623942 | Regulating the Qi of Sanjiao modulates spleen and stomach functions, enriching Qi and blood, tonifying the kidney, promoting blood circulation for blood stasis removal, eliminating phlegm, improving dementia symptoms, and retarding brain aging. | Neural Regen Res. 2018 Mar;13(3):541-548. doi: 10.4103/1673-5374.228760. | Kidney Circulation | Mechanism |
| 36819511 | Recent research has discovered a clear correlation between greater levels of circulating inflammatory markers and lower, decreasing levels of skeletal muscle mass. | Ann Transl Med. 2023 Jan 31;11(2):47. doi: 10.21037/atm-22-6082. Epub 2023 Jan 13. | Circulation | Mechanism |
| 24841896 | In the present experiments, it is considered reasonable that the application of acupuncture stimulation facilitates the local circulation system and enhances glucose consumption in peripheral tissues, thus leading to reduced glucose levels in serum, and these effects may be comparable to those produced as a result of physical exercise. | Med Sci Monit Basic Res. 2014 May 19;20:70-5. doi: 10.12659/MSMBR.890773. | Circulation | Mechanism |
| 34405366 | On the side opposite the cerebral lesion, elbow and wrist flexion, shoulder flexion and adduction, a diminished push-resistance to paralysis or circular motion were noted. | J Mol Neurosci. 2022 Jan;72(1):82-96. doi: 10.1007/s12031-021-01890-y. Epub 2021 Aug 17. | Circulation | Mechanism |
| 28672900 | The animals were anesthetized and transcardially perfused with ice-cold saline to remove circulating blood. | Exp Ther Med. 2017 Jul;14(1):107-114. doi: 10.3892/etm.2017.4479. Epub 2017 May 19. | Circulation | Mechanism |
| 28672900 | Effect of EA on 5-HT levels in the dorsal raphe nucleus of rats as determined by high-performance liquid chromatography circular electrochemical detection on day 5. | Exp Ther Med. 2017 Jul;14(1):107-114. doi: 10.3892/etm.2017.4479. Epub 2017 May 19. | Circulation | Mechanism |
| 26561562 | Reports of plasma 5-HT concentrations in FBD suggest that circulating serotonin may play a role in determining the predominant pattern of bowel function. | Acupunct Med. 2016 Jun;34(3):194-200. doi: 10.1136/acupmed-2015-010897. Epub 2015 Nov 11. | Circulation | Mechanism |
| 26561562 | Ascending interneurons activate excitatory motor neurons by releasing substance P and acetylcholine onto myocytes, resulting in circular muscle contraction. | Acupunct Med. 2016 Jun;34(3):194-200. doi: 10.1136/acupmed-2015-010897. Epub 2015 Nov 11. | Circulation | Mechanism |
| 26561562 | Descending cholinergic neurons stimulate inhibitory motor neurons releasing nitric oxide, vasoactive intestinal peptide, and adenosine triphosphate leading to circular muscle relaxation. | Acupunct Med. 2016 Jun;34(3):194-200. doi: 10.1136/acupmed-2015-010897. Epub 2015 Nov 11. | Circulation | Mechanism |
| 26339273 | In the presence of IL-6 and TNF-α causes microvascular dysfunction in the intestinal mucosa, damaging its barrier function. | Evid Based Complement Alternat Med. 2015;2015:949065. doi: 10.1155/2015/949065. Epub 2015 Aug 3. | Microcirculation | Mechanism |
| 30127121 | Activating the Shh pathway can attenuate motor and sensory deficits after stroke by increasing microvascular density and neuronal survival (Chen et al., 2017) and inhibiting neuronal apoptosis (Meng et al., 2016). | Neural Regen Res. 2018 Sep;13(9):1602-1608. doi: 10.4103/1673-5374.237123. | Microcirculation | Mechanism |
| 22369266 | Six groups received EA with uninsulated acupuncture needles (type I) or needles that were immersed in varnish and had the varnish circularly peeled 0.2 mm from the tip (type II), 0.2 mm at 3 mm (type III) or 5 mm (type IV) from the tip, or 0.2 mm at 5 and 1 mm from the tip (type V), or EA sham for 20 min. | Chin Med. 2012 Feb 27;7:3. doi: 10.1186/1749-8546-7-3. | Circulation | Mechanism |
| 22369266 | These needles had the varnish circularly peeled 0.2 mm from the tip (type II), 0.2 mm at 3 mm (type III) or 5 mm (type IV) from the tip, or 0.2 mm at 5 and 0.2 mm at 1 mm from the tip (type V) as illustrated in Figure 1. | Chin Med. 2012 Feb 27;7:3. doi: 10.1186/1749-8546-7-3. | Circulation | Mechanism |
| 35722406 | This causes progressive hypoxic-ischemic injury to the neurons and microcirculation in brain regions sensitive to injury (e.g., cerebral cortex, hippocampus), thereby simulating the pathological environment of VaD. | Ann Transl Med. 2022 May;10(10):540. doi: 10.21037/atm-22-2068. | Microcirculation | Mechanism |
| 35722406 | We used a black circular pool that measured 180 cm in diameter and 60 cm in height, which was divided into 4 quadrants (northeast, northwest, southeast, and southwest). | Ann Transl Med. 2022 May;10(10):540. doi: 10.21037/atm-22-2068. | Circulation | Mechanism |
| 34757591 | GLP-1 is a peptide hormone secreted from enteroendocrine L-cells into the hepatic portal circulation in response to ingestion of nutrients. | Mol Neurobiol. 2022 Jan;59(1):703-716. doi: 10.1007/s12035-021-02609-1. Epub 2021 Nov 10. | Circulation | Mechanism |
| 34757591 | In patients with diet-induced obesity, excess metabolites and lipid consumed in the diet result in high levels of circulating leptin, and the dysregulated leptin signaling maintains adipocyte hypertrophy and obesity. | Mol Neurobiol. 2022 Jan;59(1):703-716. doi: 10.1007/s12035-021-02609-1. Epub 2021 Nov 10. | Circulation | Mechanism |
| 31485183 | It has been confirmed by a number of relevant studies that laser needle-knives, which are an improved version of a traditional needle-knife, significantly improves blood circulation, diminishes inflammation and alleviates pain when used in clinical practice. | Saudi J Biol Sci. 2019 Feb;26(2):390-394. doi: 10.1016/j.sjbs.2018.11.011. Epub 2018 Nov 20. | Circulation | Mechanism |
| 31485183 | As shown in Table 1, compared with the normal group, the specific surface area of the model group decreased significantly, while the pore diameter increased, suggesting poorer blood circulation within the vertebral artery of the rabbits in the model group. | Saudi J Biol Sci. 2019 Feb;26(2):390-394. doi: 10.1016/j.sjbs.2018.11.011. Epub 2018 Nov 20. | Circulation | Mechanism |
| 31485183 | 1-c), a low level of capillary hyperplasia was observed on the vertebral arterial surface, suggesting improved microcirculation, increased blood flow volume and a reduction in the symptoms of CSA. | Saudi J Biol Sci. 2019 Feb;26(2):390-394. doi: 10.1016/j.sjbs.2018.11.011. Epub 2018 Nov 20. | Microcirculation Blood Flow | Mechanism |
| 31485183 | Dizziness occurs as a result of failure of the clear yang to increase because of the lack of blood and under-nourishment of the brain due to blood stasis, under-nourishment of the channels and collaterals, obstructed vessels, and failure of deficient kidney qi and yang to drive blood circulation. | Saudi J Biol Sci. 2019 Feb;26(2):390-394. doi: 10.1016/j.sjbs.2018.11.011. Epub 2018 Nov 20. | Kidney Circulation | Mechanism |
| 31485183 | Laser needle-knife therapy, essentially through a process of energy transformation and transmission, increases local temperature, dilating blood vessels, promoting angiogenesis, improving blood circulation, restoring hemodynamic balance and accelerating metabolism after the tissues have absorbed a certain number of photons and converted the light energy of laser radiation to thermal energy. | Saudi J Biol Sci. 2019 Feb;26(2):390-394. doi: 10.1016/j.sjbs.2018.11.011. Epub 2018 Nov 20. | Circulation | Mechanism |
| 18830456 | in Shanghai, observed gastric-acid secretion through changes in the pH value of physiologic saline circulated in the stomach of anesthetized rats (Ghosh & Schild method), and observed an increase in secretion by electro-acupuncture to acupuncture point ST36 with no effect from severing the ischiadic and vagus nerves or the administration of naloxone. | Evid Based Complement Alternat Med. 2008 Sep;5(3):251-6. doi: 10.1093/ecam/nem077. | Circulation | Mechanism |
| 18830456 | observed gastric-acid secretion in anesthetized rats, using a similar gastric circulation, they discovered that the response to increasing gastric-acid secretion occurred by electro-acupuncture stimulations to acupuncture point ST36, and that it disappeared when the ischiadic nerves or vagus nerves were severed, but did not disappear when the splanchnic nerves were severed. | Evid Based Complement Alternat Med. 2008 Sep;5(3):251-6. doi: 10.1093/ecam/nem077. | Circulation | Mechanism |
| 28860844 | It measures the efficiency of swimming to a hidden, submerged platform from four different locations in a circular tank filled with opaque and nontoxic water (22°C±1°C). | J Pain Res. 2017 Aug 8;10:1887-1897. doi: 10.2147/JPR.S140840. eCollection 2017. | Toxic Side Effects Circulation | Mechanism |
| 31312613 | Importantly, it has been reported that acupuncture intervention could significantly increase perfusion in local microcirculation, and affect the distribution of chemotherapeutic drugs in mice. | Front Oncol. 2019 Jul 2;9:576. doi: 10.3389/fonc.2019.00576. eCollection 2019. | Microcirculation | Mechanism |
| 31312613 | It has been reported that acupuncture could increase blood circulation in affected areas. | Front Oncol. 2019 Jul 2;9:576. doi: 10.3389/fonc.2019.00576. eCollection 2019. | Circulation | Mechanism |
| 31312613 | This result was in consistent with the above mentioned high level of COL IV and α-SMA in EAPTG group, because the integrity of microvascular basement membrane reduces the risk of metastasis. | Front Oncol. 2019 Jul 2;9:576. doi: 10.3389/fonc.2019.00576. eCollection 2019. | Microcirculation | Mechanism |
| 26889195 | The compression device was an 8-cm-long column with a 4-cm-diameter circular plate at the top and a rectangular 2.2 mm à 5.0 mm curved (concave side downward) smooth metal impactor plate at the bottom (Figure 1). | Neural Regen Res. 2015 Dec;10(12):2033-9. doi: 10.4103/1673-5374.172323. | Circulation | Mechanism |
| 26889195 | The total weight of the circular plate, column and impactor plate was 15 g. The plastic pipe was fixed to the arm of the stereotactic apparatus, and a 35-g weight was added onto the circular plate. | Neural Regen Res. 2015 Dec;10(12):2033-9. doi: 10.4103/1673-5374.172323. | Circulation | Mechanism |
| 27630692 | According to the meridian circulation and nerve segment distribution, the Baihui and Shuigou acupoints were selected using the animal acupoint atlas for experimental acupuncture (Mergenthaler et al., 2004) and the rat acupoint atlas (Hua et al., 1991). | Neural Regen Res. 2016 Jul;11(7):1099-101. doi: 10.4103/1673-5374.187042. | Circulation | Mechanism |
| 27630692 | The main functions of acupuncture treatment are improvement of blood circulation, increasing of cerebral blood flow, improvement of hemorheological properties, regulation of metabolism and neurotransmitter balance after ischemia, reduction of oxidative free radical damage, reduction of lipid peroxidation, excitatory amino acid release and toxicity, maintenance of membrane equilibrium, prevention of calcium overload in cells, regulation of gene expression, and inhibition of neuronal apoptosis (Liu et al., 2004; Dong et al., 2009). | Neural Regen Res. 2016 Jul;11(7):1099-101. doi: 10.4103/1673-5374.187042. | Toxic Side Effects Circulation Blood Flow | Mechanism |
| 23878591 | Circulation system, immunity system, and nervous system have a close relationship with meridian phenomen. | Evid Based Complement Alternat Med. 2013;2013:160651. doi: 10.1155/2013/160651. Epub 2013 Jun 26. | Immunity Circulation | Mechanism |
| 23878591 | For example, different caliber blood vessels closely related to the different types of neural endings which had different neurotransmitters and peptides regulated the flow of the peripheral blood circulation precisely then influenced the transport and distribution of body fluid and took part in the stress response and nerve-endocrine-immunity procedure. | Evid Based Complement Alternat Med. 2013;2013:160651. doi: 10.1155/2013/160651. Epub 2013 Jun 26. | Immunity Endocrinology Stress Response Circulation | Mechanism |
| 33229729 | The apparatus (Chengdu Taimeng Technology Co., Ltd., Chengdu, China) consisted of a large circular pool (120 cm in diameter, 50 cm in height) and a MT-200 Morris water maze video-tracking system (Chengdu Taimeng Technology Co., Ltd.). | Neural Regen Res. 2021 May;16(5):916-923. doi: 10.4103/1673-5374.297090. | Circulation | Mechanism |
| 33229729 | The circular platform (10 cm in diameter) was placed at the midpoint of the target quadrant and submerged approximately 1.5 cm below the surface of the water. | Neural Regen Res. 2021 May;16(5):916-923. doi: 10.4103/1673-5374.297090. | Circulation | Mechanism |
| 24665334 | The vital energy (essence) and qi are circulating along meridian and collaterals. | Evid Based Complement Alternat Med. 2014;2014:595963. doi: 10.1155/2014/595963. Epub 2014 Feb 10. | Circulation | Mechanism |
| 24665334 | The high temperature belt appeared along the circulating pathway of meridians only when Deqi (obtaining qi) arrived. | Evid Based Complement Alternat Med. 2014;2014:595963. doi: 10.1155/2014/595963. Epub 2014 Feb 10. | Circulation | Mechanism |
| 24665334 | A German subject who did not know meridian and collateral theories said that needle sensation (similarly like a worm crawling) circulated along the lateral side of the forearm after needling Yangchi (SJ4). | Evid Based Complement Alternat Med. 2014;2014:595963. doi: 10.1155/2014/595963. Epub 2014 Feb 10. | Circulation | Mechanism |
| 30505267 | The governor vessel plays an essential role in adjusting the overall blood circulation through the bladder meridian (Huang et al.,). | Front Mol Neurosci. 2018 Nov 16;11:411. doi: 10.3389/fnmol.2018.00411. eCollection 2018. | Circulation | Mechanism |
| 32967614 | Diabetic peripheral neuropathy (DPN) is a chronic microvascular complication of diabetes. | J Physiol Sci. 2020 Sep 23;70(1):45. doi: 10.1186/s12576-020-00769-8. | Microcirculation | Mechanism |
| 32967614 | DPN is a recognized microvascular complication of diabetes, and its main etiology is loss of nourishment in tendons, vessels, and skin caused by blood stasis. | J Physiol Sci. 2020 Sep 23;70(1):45. doi: 10.1186/s12576-020-00769-8. | Microcirculation | Mechanism |
| 31045558 | Briefly, a black circular pool (200Â cm in diameter, 60Â cm in height) was filled with water at room temperature. | Technol Health Care. 2019;27(S1):425-443. doi: 10.3233/THC-199038. | Circulation | Mechanism |
| 33505601 | After 15-d Sanjiao acupuncture treatments, behavioral changes were assessed by the Morris water maze test, which consisted of a circular pool, a platform, and a recording system. | World J Stem Cells. 2020 Dec 26;12(12):1576-1590. doi: 10.4252/wjsc.v12.i12.1576. | Circulation | Mechanism |
| 30899176 | 1-c), a low level of capillary hyperplasia was observed on the vertebral artery surface, which improved microcirculation, increased blood flow volume and alleviated CSA symptoms. | Saudi J Biol Sci. 2019 Mar;26(3):589-594. doi: 10.1016/j.sjbs.2018.12.007. Epub 2018 Dec 6. | Microcirculation Blood Flow | Mechanism |
| 30899176 | (1) To promote the division and proliferation of vascular endothelial cells, thereby generating new blood vessels; (2) To increase microvascular permeability as a vascular permeability factor. | Saudi J Biol Sci. 2019 Mar;26(3):589-594. doi: 10.1016/j.sjbs.2018.12.007. Epub 2018 Dec 6. | Microcirculation | Mechanism |
| 30899176 | Researchers have found that the main mechanism of injecting allogeneic blood into rabbit modeling site is the meridian qi-circulation difficulty caused by blood stasis, resulting in dizziness; local occupation, tissue-like inflammatory lesions produced by allogeneic immune responses, muscular contracture, mechanical disequilibrium, vertigo produced by direct or indirect stimulation of vertebral artery and its surrounding sympathetic nerves. | Saudi J Biol Sci. 2019 Mar;26(3):589-594. doi: 10.1016/j.sjbs.2018.12.007. Epub 2018 Dec 6. | Immunity Circulation | Mechanism |
| 30899176 | As a novel technology, laser acupotomy is currently rarely used in CSA treatment, but related studies have shown that it has significant clinical efficacy in improving blood circulation and anti-inflammatory analgesia. | Saudi J Biol Sci. 2019 Mar;26(3):589-594. doi: 10.1016/j.sjbs.2018.12.007. Epub 2018 Dec 6. | Circulation | Mechanism |
| 30899176 | used laser acupotomy to treat temporomandibular disorders (TMD), and also found that laser irradiation can relieve pain, relax muscles and promote blood circulation, and can regulate metabolism, change histopathological conditions and promote the recovery of tissue health, and it is safe and efficient without side effects. | Saudi J Biol Sci. 2019 Mar;26(3):589-594. doi: 10.1016/j.sjbs.2018.12.007. Epub 2018 Dec 6. | Side Effects Circulation | Mechanism |
| 30899176 | After being absorbed by a certain photon, the tissue irradiated by laser light converts light energy into heat energy, which increases the local temperature, dilates blood vessels and promotes angiogenesis, and improves blood circulation, restores hemodynamic balance and promotes metabolism. | Saudi J Biol Sci. 2019 Mar;26(3):589-594. doi: 10.1016/j.sjbs.2018.12.007. Epub 2018 Dec 6. | Circulation | Mechanism |
| 30899176 | From the results of the phased study of this project, the main mechanism of laser acupotomy combination therapy in the treatment of CSA is to stimulate the generation of vertebral artery microvessels by the PI3K- AKT- VEGF signal path, thereby effectively improving the blood circulation of the vertebral artery, changing the abnormality of vertebral artery hemodynamics caused by CSA, and facilitating local blood supply. | Saudi J Biol Sci. 2019 Mar;26(3):589-594. doi: 10.1016/j.sjbs.2018.12.007. Epub 2018 Dec 6. | Hemodynamics Circulation | Mechanism |
| 33193035 | The double stranded PCR products were heat denatured and circularized by the splint oligo sequence. | Front Neurol. 2020 Oct 30;11:580997. doi: 10.3389/fneur.2020.580997. eCollection 2020. | Circulation | Mechanism |
| 21799673 | According to traditional Chinese medicine, overall health depends of formation, maintenance and circulation of Yin and Yang, and their imbalance results in the development of diseases. | Evid Based Complement Alternat Med. 2011;2011:217946. doi: 10.1093/ecam/neq036. Epub 2011 Jun 5. | Circulation | Mechanism |
| 21799673 | Acute inflammation involves microvascular changes with increased vascular permeability, flow of exudation, including plasmatic protein, cell migration (primarily neutrophils) and amplification of endogenous chemical mediators into the site of injury. | Evid Based Complement Alternat Med. 2011;2011:217946. doi: 10.1093/ecam/neq036. Epub 2011 Jun 5. | Microcirculation | Mechanism |
| 37384285 | In traditional acupuncture theory, the use of warm needle acupuncture is described to transmit moxa heat deeply into the body by way of acupuncture points, promoting the circulation of the Qi-Blood and activating the meridian system. | Front Neurol. 2023 Jun 13;14:1168012. doi: 10.3389/fneur.2023.1168012. eCollection 2023. | Circulation | Mechanism |
| 26279808 | A number of studies have proved that early enriched environments stimulation in pups after birth can increase dendritic branching in motor cortex and lengthening in visual cortex and can improve blood circulation in the brain tissue that brings structural changes as well as enhance metabolism in the brain. | J Korean Neurosurg Soc. 2015 Jul;58(1):14-21. doi: 10.3340/jkns.2015.58.1.14. Epub 2015 Jul 31. | Circulation | Mechanism |
| 25206919 | Modern studies have demonstrated that acupuncture and moxibustion at Baihui and Shenshu regulate acetylcholinesterase activity, elevate cortical excitability and cerebral blood flow, improve cerebral circulation, protect against free radical oxidation and neurotoxic injury, suppress inflammation and cell apoptosis, improve learning and memory functions, and effectively treat senile dementia (Mao et al., 2012; Luo et al., 2013). | Neural Regen Res. 2014 May 1;9(9):968-72. doi: 10.4103/1673-5374.133148. | Toxic Side Effects Learning and Memory Ability Circulation Blood Flow | Mechanism |
| 37635258 | Electroacupuncture-driven endogenous circulating serum exosomes as a potential therapeutic strategy for sepsis | Chin Med. 2023 Aug 27;18(1):106. doi: 10.1186/s13020-023-00816-7. | Circulation | Mechanism |
| 37635258 | This paper explores the possibility of electroacupuncture-driven endogenous circulating serum exosomes and their carried miRNAs as a potential treatment for sepsis. | Chin Med. 2023 Aug 27;18(1):106. doi: 10.1186/s13020-023-00816-7. | Circulation | Mechanism |
| 37635258 | Electroacupuncture-driven endogenous circulating serum exosomes and their carried miRNAs may be a potential treatment for sepsis. | Chin Med. 2023 Aug 27;18(1):106. doi: 10.1186/s13020-023-00816-7. | Circulation | Mechanism |
| 37635258 | was extracted from the circulating serum of normal mice that had undergone EA for different days. | Chin Med. 2023 Aug 27;18(1):106. doi: 10.1186/s13020-023-00816-7. | Circulation | Mechanism |
| 37635258 | B WB was used to identify exosomes markers (CD9, CD63, TSG101), exosomes extracted from the circulating serum of normal mice treated with EA7. | Chin Med. 2023 Aug 27;18(1):106. doi: 10.1186/s13020-023-00816-7. | Circulation | Mechanism |
| 37635258 | WB results showed that exosome markers (CD9, CD63, TSG101) extracted from the circulating serum of normal mice treated with electroacupuncture for 7 days (EA7) were positive (Fig. 2B). | Chin Med. 2023 Aug 27;18(1):106. doi: 10.1186/s13020-023-00816-7. | Circulation | Mechanism |
| 37635258 | The exosomes extracted from the circulating serum of normal mice treated with EA1, EA7, EA14, EA21 and without EA treatment (EA0) were round or round-like (Fig. 2C). | Chin Med. 2023 Aug 27;18(1):106. doi: 10.1186/s13020-023-00816-7. | Circulation | Mechanism |
| 37635258 | The particle size peaks of exosomes extracted from the circulating serum of normal mice treated with EA0, EA1, EA7, EA14, EA21 were 124.8 nm, 113.6 nm, 131.4 nm, 127.6 nm and 99.6 nm (Fig. 2D). | Chin Med. 2023 Aug 27;18(1):106. doi: 10.1186/s13020-023-00816-7. | Circulation | Mechanism |
| 37635258 | B Effects of exosomes (0.4Â mg/mL) extracted from the circulating serum of normal mice treated with EA0, EA1, EA7, EA14, EA21 on the survival rate of sepsis mice. | Chin Med. 2023 Aug 27;18(1):106. doi: 10.1186/s13020-023-00816-7. | Circulation | Mechanism |
| 37635258 | C Effects of different concentrations (2Â mg/mL, 0.8Â mg/mL, 0.4Â mg/mL, 0.2Â mg/mL, 0.08Â mg/mL) of exosomes extracted from the circulating serum of normal mice treated with EA7 on the survival rate of sepsis mice. | Chin Med. 2023 Aug 27;18(1):106. doi: 10.1186/s13020-023-00816-7. | Circulation | Mechanism |
| 37635258 | Exosomes extracted from the circulating serum of normal mice treated with EA for different days were intraperitoneally injected into sepsis mice. | Chin Med. 2023 Aug 27;18(1):106. doi: 10.1186/s13020-023-00816-7. | Circulation | Mechanism |
| 37635258 | Our results showed that exosomes extracted from the circulating serum of normal mice treated with EA7 (0.4Â mg/mL) had the greatest effect on the survival of sepsis mice. | Chin Med. 2023 Aug 27;18(1):106. doi: 10.1186/s13020-023-00816-7. | Circulation | Mechanism |
| 37635258 | NC-exo group: exosomes extracted from the circulating serum of normal mice. | Chin Med. 2023 Aug 27;18(1):106. doi: 10.1186/s13020-023-00816-7. | Circulation | Mechanism |
| 37635258 | Acu-exo group: exosomes extracted from the circulating serum of normal mice treated with EA7 | Chin Med. 2023 Aug 27;18(1):106. doi: 10.1186/s13020-023-00816-7. | Circulation | Mechanism |
| 37635258 | MiRNA sequencing results showed that EA altered the expression of multiple miRNAs in circulating serum exosomes of normal mice. | Chin Med. 2023 Aug 27;18(1):106. doi: 10.1186/s13020-023-00816-7. | Circulation | Mechanism |
| 37635258 | Endogenous circulating exosomes, driven by EA, may carry multiple targets for sepsis treatment. | Chin Med. 2023 Aug 27;18(1):106. doi: 10.1186/s13020-023-00816-7. | Circulation | Mechanism |
| 29623933 | Stimulation via EA and Mox has been shown to have direct effects on local areas and could promote blood circulation, decrease the edema of nerves, and improve the nutrition of muscle, thereby promoting functional recovery. | Neural Regen Res. 2018 Mar;13(3):477-483. doi: 10.4103/1673-5374.228731. | Circulation | Mechanism |
| 34108361 | Recently, emerging evidence suggested that Klf4 was involved in the protective effect of microvascular endothelial cells from ischemic stroke injury by inhibiting apoptosis and inflammation. | Exp Anim. 2021 Nov 10;70(4):469-478. doi: 10.1538/expanim.21-0034. Epub 2021 Jun 10. | Microcirculation | Mechanism |
| 35478723 | Acupuncture and laser needle knife can regulate the coagulation and fibrinolysis system in CSA, stimulate capillary and micropore hyperplasia, reduce blood viscosity, and improve blood circulation, which may be one of the therapeutic mechanisms behind the laser needle knife treatment of CSA. | Front Surg. 2022 Apr 11;9:778608. doi: 10.3389/fsurg.2022.778608. eCollection 2022. | Circulation | Mechanism |
| 35478723 | This suggests that the treatment improves microcirculation and blood flow and alleviates CSA symptoms. | Front Surg. 2022 Apr 11;9:778608. doi: 10.3389/fsurg.2022.778608. eCollection 2022. | Microcirculation Blood Flow | Mechanism |
| 35478723 | Acupuncture and laser needle knife can regulate the coagulation and fibrinolysis system in CSA, reduce blood viscosity, and improve blood circulation, which may be one of the therapeutic mechanisms behind laser needle knife treatment of CSA. | Front Surg. 2022 Apr 11;9:778608. doi: 10.3389/fsurg.2022.778608. eCollection 2022. | Circulation | Mechanism |
| 28386185 | Ilex pubescens promotes blood circulation and removes blood stasis drugs. | Saudi J Biol Sci. 2017 Mar;24(3):595-602. doi: 10.1016/j.sjbs.2017.01.031. Epub 2017 Jan 23. | Circulation | Mechanism |
| 28386185 | It can promote blood circulation (in Chinese it refers as Huoxue Tongmai). | Saudi J Biol Sci. 2017 Mar;24(3):595-602. doi: 10.1016/j.sjbs.2017.01.031. Epub 2017 Jan 23. | Circulation | Mechanism |
| 28386185 | The dry roots of Ilex pubescens plant (or holly of Ilex genus) are able to promote blood circulation and remove blood stasis. | Saudi J Biol Sci. 2017 Mar;24(3):595-602. doi: 10.1016/j.sjbs.2017.01.031. Epub 2017 Jan 23. | Circulation | Mechanism |
| 28386185 | Pharmacological studies have shown that, holly (or Mao Dongqing) has the effect of promoting blood circulation and removing blood stasis. | Saudi J Biol Sci. 2017 Mar;24(3):595-602. doi: 10.1016/j.sjbs.2017.01.031. Epub 2017 Jan 23. | Circulation | Mechanism |
| 28386185 | Cerebral ischemia and reperfusion appears microcirculation, inadequate supply of oxygen and glucose, ATP was rapidly depleted, mitochondrial ATP synthase failure, resulting in ATP dependent enzymes (including Ca2-ATP enzyme and Na+-K+-ATPase enzyme activity decreased, resulting in a massive outflow of intracellular K+, Na+, Clâ and Ca2+ large inflows of cells, resulting in cell, ion imbalance. | Saudi J Biol Sci. 2017 Mar;24(3):595-602. doi: 10.1016/j.sjbs.2017.01.031. Epub 2017 Jan 23. | Microcirculation | Mechanism |
| 28386185 | It not only promotes blood circulation and removes blood stasis. | Saudi J Biol Sci. 2017 Mar;24(3):595-602. doi: 10.1016/j.sjbs.2017.01.031. Epub 2017 Jan 23. | Circulation | Mechanism |
| 30028333 | The pathophysiology of SCI involves the primary injury and the subsequent secondary injury, which results from a progressive local cascade of tissue destruction, including the change in the microenvironment of the injured spinal cord (ischemia of the microcirculation, edema, inflammation, glutamatergic excitotoxicity) and apoptosis. | Neural Regen Res. 2018 Jul;13(7):1241-1246. doi: 10.4103/1673-5374.235062. | Microcirculation Toxic Side Effects | Mechanism |
| 30028333 | The disturbance of the microcirculation after SCI is an important link between neurological injury, cardiovascular complications, and the change in hemodynamics after SCI (Sezer et al., 2015), which are consistent with stasis of the Governor Vessels in traditional Chinese medicine. | Neural Regen Res. 2018 Jul;13(7):1241-1246. doi: 10.4103/1673-5374.235062. | Microcirculation Cardiovascular Hemodynamics | Mechanism |
| 30028333 | Once SCI occurs, the platelet-activating factor content will rise rapidly in the SCI tissue, and prompt microvascular thrombosis, vascular endothelial cell damage, increased permeability of blood vessel walls, and blood-spinal cord barrier disruption, thereby altering the microenvironment of the injured spinal cord (Lindsberg et al., 1990; Faden et al., 1992; Xiao et al., 1996). | Neural Regen Res. 2018 Jul;13(7):1241-1246. doi: 10.4103/1673-5374.235062. | Microcirculation | Mechanism |
| 25887143 | ACTH enters blood circulation and acts on the adrenal gland to promote the synthesis and secretion of glucocorticoids. | BMC Complement Altern Med. 2015 Mar 27;15:87. doi: 10.1186/s12906-015-0625-4. | Circulation | Mechanism |
| 25120577 | As evidences given by recently extensive reports, the beneficial effects of acupuncture on brain ischemic damage in vivo or in vitro mainly focus on microcirculation, anti-apoptotic, anti-inflammation, neuron protection, brain metabolism. | Evid Based Complement Alternat Med. 2014;2014:962343. doi: 10.1155/2014/962343. Epub 2014 Jul 10. | Brain Protection Neuroprotection Microcirculation | Mechanism |
| 25120577 | However, acupuncture increasing the cerebral blood supply in ischemia region is helpful to ameliorate the hypoxic-ischemic situation to a certain extent which may be relevant to regulating vascular caliber, establishing collateral circulation and enhancing angiogenesis. | Evid Based Complement Alternat Med. 2014;2014:962343. doi: 10.1155/2014/962343. Epub 2014 Jul 10. | Circulation | Mechanism |
| 25120577 | Thus, the treatment principle of stroke should unblock the blockage in brain and promote circulation of qi in body. | Evid Based Complement Alternat Med. 2014;2014:962343. doi: 10.1155/2014/962343. Epub 2014 Jul 10. | Circulation | Mechanism |
| 29946236 | Patients with major depressive disorder (MDD) have greater pro-inflammatory cytokines in peripheral circulation and some in brain regions, such as: interleukin-6 (IL-6), IL-1β and C-reactive protein (CRP; Howren et al.,; Jacoby et al.,). | Front Mol Neurosci. 2018 May 31;11:149. doi: 10.3389/fnmol.2018.00149. eCollection 2018. | Circulation | Mechanism |
| 31835339 | The FFA pool in the circulation is the major source of FFA in the liver, but no remarkable difference in the hepatic expression of receptors related to the lipid uptake were noted between NG and AG mice. | Metabolites. 2019 Dec 9;9(12):299. doi: 10.3390/metabo9120299. | Circulation | Mechanism |
| 36116306 | Once injured (including bone fractures), blood circulation immediately becomes stagnant leading to swelling. | Int J Surg Case Rep. 2022 Oct;99:107600. doi: 10.1016/j.ijscr.2022.107600. Epub 2022 Sep 7. | Circulation Inflammatory Pain | Mechanism |
| 36116306 | Therefore, in the treatment of trauma, increasing the blood circulation is indispensable. | Int J Surg Case Rep. 2022 Oct;99:107600. doi: 10.1016/j.ijscr.2022.107600. Epub 2022 Sep 7. | Circulation | Mechanism |
| 36116306 | Therefore, acupuncture on the acupoints on the meridians will help blood circulation. | Int J Surg Case Rep. 2022 Oct;99:107600. doi: 10.1016/j.ijscr.2022.107600. Epub 2022 Sep 7. | Circulation | Mechanism |
| 36116306 | We used acupressure points: Zusanli (ST-36), Diji (SP-8), Yinlingquan (SP-9), Yanglingquan (GB-34), Sanyinjiao (SP-6) and Xuehai (SP-10) as local acupoints that have the effect of qi and blood circulating, helping to relieve pain. | Int J Surg Case Rep. 2022 Oct;99:107600. doi: 10.1016/j.ijscr.2022.107600. Epub 2022 Sep 7. | Circulation | Mechanism |
| 36116306 | The Diji is the 8th point of the spleen meridian, which is used in qi disorders caused by circulatory stagnation. | Int J Surg Case Rep. 2022 Oct;99:107600. doi: 10.1016/j.ijscr.2022.107600. Epub 2022 Sep 7. | Circulation | Mechanism |
| 36116306 | Therefore, electro-acupuncture of acupoints has the effect of activating blood circulation, reducing moisture, combined with proper rehabilitation, can help ventilate the blood, help reduce swelling in patients with fractures after surgery. | Int J Surg Case Rep. 2022 Oct;99:107600. doi: 10.1016/j.ijscr.2022.107600. Epub 2022 Sep 7. | Circulation Inflammatory Pain | Mechanism |
| 36116306 | Therefore, electro-acupuncture at the qi and blood circulation acupoints can help to ventilate the blood and help reduce swelling in patients with fractures after surgery. | Int J Surg Case Rep. 2022 Oct;99:107600. doi: 10.1016/j.ijscr.2022.107600. Epub 2022 Sep 7. | Circulation Inflammatory Pain | Mechanism |
| 27843474 | Grooming behavior: cleaning the body and face by making circular movements with the forepaws. | Evid Based Complement Alternat Med. 2016;2016:1846296. doi: 10.1155/2016/1846296. Epub 2016 Oct 24. | Circulation | Mechanism |
| 30766475 | The Morris water maze consisted of a circular tank (diameter: 90 cm; height: 50 cm) filled with water to a depth of 30 cm, maintained at 24 ± 1°C, and rendered opaque with black ink. | Front Neurosci. 2019 Jan 31;13:37. doi: 10.3389/fnins.2019.00037. eCollection 2019. | Circulation | Mechanism |
| 30766475 | A removable circular platform (diameter: 9.5 cm; height: 28 cm) with the top surface 1 cm below the water was located inside the pool. | Front Neurosci. 2019 Jan 31;13:37. doi: 10.3389/fnins.2019.00037. eCollection 2019. | Circulation | Mechanism |
| 30766475 | Body temperature was maintained at approximately 37°C using a circulating water system (SC100-S14P, Thermo Scientific). | Front Neurosci. 2019 Jan 31;13:37. doi: 10.3389/fnins.2019.00037. eCollection 2019. | Circulation | Mechanism |