In clinical practice, acupuncture anesthesia presents a multitude of advantages, pivotal among these being Body System Protection. This technique supports the body's natural defenses, reducing the physiological stress often associated with surgical procedures. By modulating the body's response to pain, acupuncture anesthesia allows for a lower Dosage of Medication, significantly reducing the potential for drug-related side effects. Furthermore, this approach plays a crucial role in Emotion Regulation, helping patients maintain a calm and stable emotional state, which is essential for a positive surgical outcome. The impact of acupuncture on the nervous system not only aids in Pain Relief but also promotes Enhanced Recovery After Surgery. Patients tend to experience faster recuperation times, attributed to the holistic nature of this method. Additionally, acupuncture anesthesia is associated with a Lower Incidence of Side Effects compared to conventional anesthetics. Its ability to modulate and balance the body's responses makes it an invaluable tool in the realm of modern medicine, offering a safer, more patient-centered approach to pain management and recovery.

           
Pain Relief
Cancer Pain
Acupuncture anesthesia offers effective cancer pain relief, improving the quality of life for cancer patients.
Pain Relief
Acupuncture anesthesia provides robust pain relief, reducing the need for postoperative analgesics.
Analgesic Effect
Acupuncture anesthesia's analgesic effect offers profound pain relief, particularly beneficial for patients with chronic pain conditions.
Visceral Pain
Acupuncture anesthesia can address visceral pain, improving the surgical experience for patients.
Neuralgia
Acupuncture anesthesia offers relief from neuralgia, reducing pain and discomfort.
Inflammatory Pain
Acupuncture anesthesia's anti-inflammatory properties make it effective in managing inflammatory pain conditions.

Acupuncture anesthesia for Pain Relief-Pain Relief


PMID Evidence Source Keyword Type
11068159 Acupuncture, transcutaneous electrical nerve stimulation, supportive group therapy, self-hypnosis, and massage therapy may provide pain relief in cancer pain or in dying patients. J Pain Symptom Manage. 2000 Nov;20(5):374-87. doi: 10.1016/s0885-3924(00)00190-1. Cancer Pain Pain Relief Review
11075429 Acupuncture is the last step of the treatment cascade in out patients in any case, because acupuncture does not only serve as treatment option for pain relief, but also and even more so has an harmonizing effect upon physical and psychological disturbances. Wien Med Wochenschr. 2000;150(13-14):286-94. Pain Relief Review
11549194 In North America, acupuncture is primarily for pain relief. South Med J. 2001 Aug;94(8):813-6. Pain Relief Review
11549194 CONCLUSIONS: Acupuncture is most frequently used in China and North America for pain relief. South Med J. 2001 Aug;94(8):813-6. Pain Relief Review
11710415 Although some of the mechanisms of acupuncture as it applies to pain relief have been studied, little is known of the positive and/or negative effects of this procedure on the physical performance parameters of healthy people, particularly highly trained athletes. J Strength Cond Res. 2001 May;15(2):266-71. Pain Relief Review
12168251 The muscle twitch in myofascial pain relief: effects of acupuncture and other needling methods. Electromyogr Clin Neurophysiol. 2002 Jul-Aug;42(5):307-11. Pain Relief Review
12168251 Proposed is that needling methods such as acupuncture, primarily effect pain relief in myofascial pain through a local mechanism, elicitation of muscle twitches. Electromyogr Clin Neurophysiol. 2002 Jul-Aug;42(5):307-11. Pain Relief Review
12365644 Therefore, the benefit of acupuncture in musculoskeletal pain relief for which it is most commonly used, would not be limited to classical acupuncture points on the meridians. Zhonghua Yi Xue Za Zhi (Taipei). 2002 Jul;65(7):299-302. Pain Relief Review
12365644 These observations suggest that needle induced local muscle twitches mediate musculoskeletal pain relief in acupuncture. Zhonghua Yi Xue Za Zhi (Taipei). 2002 Jul;65(7):299-302. Pain Relief Review
12804474 The trial of acupuncture decreased the need for pain relief (relative risk (RR) 0.56, 95% confidence interval (CI) 0.39 to 0.81). Cochrane Database Syst Rev. 2003;(2):CD003521. doi: 10.1002/14651858.CD003521. Pain Relief Review
14676739 The studies on the use of acupuncture to achieve pain relief and analgesia during labor show more controversial results, mainly due to the great heterogeneity of applied treatments and some methodological biases. Minerva Ginecol. 2003 Dec;55(6):503-10. Pain Relief Review
15584377 It can be seen therefore that research into acupuncture for pain relief is an inherently difficult task, which requires much sensitivity and careful planning in order to minimise error when drawing conclusions. Adv Exp Med Biol. 2004;546:217-27. doi: 10.1007/978-1-4757-4820-8_16. Pain Relief Review
15584377 Few good quality rigorous trials exist to support the use of acupuncture for pain relief in general. Adv Exp Med Biol. 2004;546:217-27. doi: 10.1007/978-1-4757-4820-8_16. Pain Relief Review
15628777 Acupuncture appears to be useful to treat back pain, but patients should probably be advised to take advantage of any pain relief obtained to maintain or increase their activity. Acupunct Med. 2004 Dec;22(4):203-6. doi: 10.1136/aim.22.4.203. Pain Relief Review
15674876 For chronic low-back pain there is evidence of pain relief and functional improvement for acupuncture, compared to no treatment or sham therapy. Cochrane Database Syst Rev. 2005 Jan 25;(1):CD001351. doi: 10.1002/14651858.CD001351.pub2. Pain Relief Review
15674876 For chronic low-back pain, acupuncture is more effective for pain relief and functional improvement than no treatment or sham treatment immediately after treatment and in the short-term only. Cochrane Database Syst Rev. 2005 Jan 25;(1):CD001351. doi: 10.1002/14651858.CD001351.pub2. Pain Relief Review
15834340 For chronic low back pain, there is evidence of pain relief and functional improvement for acupuncture compared to no treatment or sham therapy. Spine (Phila Pa 1976). 2005 Apr 15;30(8):944-63. doi: 10.1097/01.brs.0000158941.21571.01. Pain Relief Review
15834340 For chronic low back pain, acupuncture is more effective for pain relief and functional improvement than no treatment or sham treatment immediately after treatment and in the short-term only. Spine (Phila Pa 1976). 2005 Apr 15;30(8):944-63. doi: 10.1097/01.brs.0000158941.21571.01. Pain Relief Review
15979024 RESULTS: Of the seven studies included, one high quality randomised clinical trial of ear acupuncture showed statistically significant pain relief in comparison with placebo ear acupuncture. Eur J Pain. 2005 Aug;9(4):437-44. doi: 10.1016/j.ejpain.2004.10.004. Epub 2004 Nov 11. Pain Relief Review
16783282 The clinical effectiveness of acupuncture for pain relief--you can be certain of uncertainty. Acupunct Med. 2006 Jun;24(2):71-9. doi: 10.1136/aim.24.2.71. Pain Relief Review
16783282 This paper critically reviews the processes used to establish one-sentence statements about the effectiveness of acupuncture for pain relief. Acupunct Med. 2006 Jun;24(2):71-9. doi: 10.1136/aim.24.2.71. Pain Relief Review
16783282 Some one-sentence statements claim that acupuncture is not clinically effective because systematic reviews of clinical trials find similar amounts of pain relief between sham acupuncture and real acupuncture. Acupunct Med. 2006 Jun;24(2):71-9. doi: 10.1136/aim.24.2.71. Pain Relief Review
16783282 It is hoped that this will be reflected in a reappraisal of some of the negative one-sentence statements about the effectiveness of acupuncture for pain relief. Acupunct Med. 2006 Jun;24(2):71-9. doi: 10.1136/aim.24.2.71. Pain Relief Review
16850779 Recent evidence suggests that manual acupuncture is effective for reducing preoperative anxiety and for postoperative pain relief. Best Pract Res Clin Anaesthesiol. 2006 Jun;20(2):303-14. doi: 10.1016/j.bpa.2005.10.009. Pain Relief Anxiety Review
16856065 For chronic mechanical neck disorders, there was moderate evidence that acupuncture was more effective for pain relief than some types of sham controls, measured immediately post-treatment. Cochrane Database Syst Rev. 2006 Jul 19;(3):CD004870. doi: 10.1002/14651858.CD004870.pub3. Pain Relief Review
17187468 P-Stim auricular electroacupuncture stimulation device for pain relief. Expert Rev Med Devices. 2007 Jan;4(1):23-32. doi: 10.1586/17434440.4.1.23. Pain Relief Review
17224820 For chronic mechanical neck disorders, there was moderate evidence that acupuncture was more effective for pain relief than some types of sham controls, measured immediately posttreatment. Spine (Phila Pa 1976). 2007 Jan 15;32(2):236-43. doi: 10.1097/01.brs.0000252100.61002.d4. Pain Relief Review
17443503 For women with both pelvic and back pain, in one study, acupuncture was more effective than physiotherapy in reducing the intensity of their pain; stretching exercises resulted in more total pain relief (60%) than usual care (11%); and 60% of those who received acupuncture reported less intense pain, compared to 14% of those receiving usual prenatal care. Cochrane Database Syst Rev. 2007 Apr 18;(2):CD001139. doi: 10.1002/14651858.CD001139.pub2. Pain Relief Review
17674552 The studies have shown that acupuncture serves as an effective complementary treatment to standard care, improves function and provides pain relief for people with osteoarthritis of the knee. Harefuah. 2007 May;146(5):354-7, 406. Pain Relief Review
17943847 CHM also resulted in better pain relief than acupuncture (2 RCTs; RR 1.75, 95% CI 1.09 to 2.82) and heat compression (1 RCT; RR 2.08, 95% CI 2.06 to 499.18). Cochrane Database Syst Rev. 2007 Oct 17;(4):CD005288. doi: 10.1002/14651858.CD005288.pub2. Pain Relief Review
18404372 The past decades has seen remarkable progress in exploring the central mechanisms of acupuncture-induced pain relief, including the neurotransmitter release and expression of particular receptors and genes in the spinal cord and the brain stem regions. Neurochem Res. 2008 Oct;33(10):1950-5. doi: 10.1007/s11064-008-9692-y. Epub 2008 Apr 11. Pain Relief Review
18425916 Chinese herbal medicine also resulted in better pain relief than acupuncture (2 RCTs; RR 1.75, 95% CI 1.09 to 2.82) and heat compression (1 RCT; RR 2.08, 95% CI 2.06 to 499.18). Cochrane Database Syst Rev. 2008 Apr 16;(2):CD005288. doi: 10.1002/14651858.CD005288.pub3. Pain Relief Review
18440533 Despite these deficiencies, acupuncture can be considered as an effective alternative for pain relief during oocyte retrieval in patients who cannot tolerate side effects of conscious sedation. Fertil Steril. 2008 Jul;90(1):1-13. doi: 10.1016/j.fertnstert.2008.02.094. Epub 2008 Apr 28. Pain Relief Side Effects Sedation Review
18550160 The benefits achieved through acupuncture treatment are thought to be a result of hormonal regulation, altered smooth muscle motility, and general stress and/or pain relief from musculoskeletal or environmental conditions. Theriogenology. 2008 Aug;70(3):430-4. doi: 10.1016/j.theriogenology.2008.05.001. Epub 2008 Jun 11. Pain Relief Review
18759255 Acupuncture for pain relief in patients with rheumatoid arthritis: a systematic review. Arthritis Rheum. 2008 Sep 15;59(9):1249-56. doi: 10.1002/art.24009. Pain Relief Review
18759255 OBJECTIVE: To systematically review the efficacy of acupuncture on pain relief in patients with rheumatoid arthritis (RA). Arthritis Rheum. 2008 Sep 15;59(9):1249-56. doi: 10.1002/art.24009. Pain Relief Review
18978583 There is moderate evidence that acupuncture is more effective than no treatment, and strong evidence of no significant difference between acupuncture and sham acupuncture, for short-term pain relief. Spine (Phila Pa 1976). 2008 Nov 1;33(23):E887-900. doi: 10.1097/BRS.0b013e318186b276. Pain Relief Review
19216662 Moreover, the meta-analysis with a pooled SMD of -0.53 (95% CI, -0.94 to -0.11) showed that acupuncture was significantly more effective than sham acupuncture for pain relief. J Altern Complement Med. 2009 Feb;15(2):133-45. doi: 10.1089/acm.2008.0135. Pain Relief Review
19370841 Acupuncture--propagated indications beyond pain-relief therapy. Versicherungsmedizin. 2009 Mar 1;61(1):19-24. Pain Relief Review
19370841 Since the 1970s acupuncture has been carried out more and more in Germany - especially within the context of pain-relief therapy. Versicherungsmedizin. 2009 Mar 1;61(1):19-24. Pain Relief Review
19370841 Less known is the fact that acupuncture is not only used for pain-relief therapy, but that a lot more indications have emerged over the last 20 years. Versicherungsmedizin. 2009 Mar 1;61(1):19-24. Pain Relief Review
19454042 CONCLUSIONS: In this systematic review we present information relating to the effectiveness and safety of the following interventions: acupuncture, amitriptyline, benzodiazepines, botulinum toxin, cognitive behavioural therapy, Indian head massage, mirtazapine, regular acute pain relief medication, relaxation and electromyographic biofeedback, serotonin reuptake inhibitor antidepressants, and tricyclic antidepressants (other than amitriptyline). BMJ Clin Evid. 2007 Jan 1;2007:1205. Pain Relief Review
19747272 Findings from the review also highlighted promising evidence for the effectiveness of acupuncture to manage back and pelvic pain, acupuncture-type interventions to induce change in breech presentation, and pain relief in labor. Birth. 2009 Sep;36(3):246-53. doi: 10.1111/j.1523-536X.2009.00329.x. Pain Relief Review
20026952 This paper evaluates whether the updated harms guidelines have been implemented in RCTs evaluating acupuncture for pain relief. Clin J Pain. 2010 Jan;26(1):43-8. doi: 10.1097/AJP.0b013e3181b2c985. Pain Relief Review
20071924 Short-term pain relief may be obtained from spinal manipulative therapy or acupuncture. Curr Sports Med Rep. 2010 Jan-Feb;9(1):60-6. doi: 10.1249/JSR.0b013e3181caa9b6. Pain Relief Review
20091561 Optimal technique and dose need to be determined.Thoracic Manipulation for acute/chronic neck pain : Low quality evidence supported thoracic manipulation as an additional therapy for pain reduction (NNT 7; 46.6% treatment advantage) and increased function (NNT 5; 40.6% treatment advantage) in acute pain and favoured a single session of thoracic manipulation for immediate pain reduction compared to placebo for chronic neck pain (NNT 5, 29% treatment advantage).Mobilisation for subacute/chronic neck pain: In addition to the evidence noted above, low quality evidence for subacute and chronic neck pain indicated that 1) a combination of Maitland mobilisation techniques was similar to acupuncture for immediate pain relief and increased function; 2) there was no difference between mobilisation and acupuncture as additional treatments for immediate pain relief and improved function; and 3) neural dynamic mobilisations may produce clinically important reduction of pain immediately post-treatment. Cochrane Database Syst Rev. 2010 Jan 20;(1):CD004249. doi: 10.1002/14651858.CD004249.pub3. Pain Relief Review
20170770 Among non-pharmacological therapies, ES for pain relief was unchanged for self-management, education, exercise and acupuncture. Osteoarthritis Cartilage. 2010 Apr;18(4):476-99. doi: 10.1016/j.joca.2010.01.013. Epub 2010 Feb 11. Pain Relief Review
20170995 Overall, there was little difference in satisfaction with pain relief or in pain ratings between TENS and control groups, although women receiving TENS to acupuncture points were less likely to report severe pain (risk ratio 0.41, 95% confidence interval 0.32-0.55). Midwifery. 2011 Oct;27(5):e141-8. doi: 10.1016/j.midw.2009.12.004. Epub 2010 Feb 18. Pain Relief Review
20359125 There is some evidence that acupuncture may induce pain relief by changing the regional blood flow through somatosympathetic reflex (SSR). Chin J Physiol. 2009 Nov 30;52(5 Suppl):345-57. doi: 10.4077/cjp.2009.amk043. Pain Relief Blood Flow Review
20438555 Acupuncture for pain relief in labour: a systematic review and meta-analysis. BJOG. 2010 Jul;117(8):907-20. doi: 10.1111/j.1471-0528.2010.02570.x. Epub 2010 Apr 28. Pain Relief Review
20438555 BACKGROUND: Acupuncture is frequently used for pain relief in labour, but the evidence is not clear. BJOG. 2010 Jul;117(8):907-20. doi: 10.1111/j.1471-0528.2010.02570.x. Epub 2010 Apr 28. Pain Relief Review
20438555 SELECTION CRITERIA: All randomised controlled trials (RCTs) involving women receiving acupuncture alone, or as an adjunct to conventional analgesia, for pain relief in labour were considered. BJOG. 2010 Jul;117(8):907-20. doi: 10.1111/j.1471-0528.2010.02570.x. Epub 2010 Apr 28. Pain Relief Review
20550871 CONCLUSION: Acupuncture is effective for pain relief. Zhong Xi Yi Jie He Xue Bao. 2010 Jun;8(6):501-9. doi: 10.3736/jcim20100601. Pain Relief Review
20597619 This review summarizes the evidence of acupuncture in pain relief for oocyte retrieval, improving pregnancy outcomes of in vitro fertilization treatment, management of ovulation disorders, male subfertility, primary dysmenorrhea, endometriosis and menopausal symptoms. Womens Health (Lond). 2010 Jul;6(4):551-63. doi: 10.2217/whe.10.39. Pain Relief Review
20633471 It is possible that by affecting afferent nerve signaling, acupuncture may influence the release of endogenous opioids to promote pain relief. J Acupunct Meridian Stud. 2009 Mar;2(1):26-33. doi: 10.1016/S2005-2901(09)60012-1. Epub 2009 Apr 7. Pain Relief Review
21249694 Long-term pain relief was reported for both acupuncture and point-injection compared with medication during the last 10 days of treatment. Cochrane Database Syst Rev. 2011 Jan 19;(1):CD007753. doi: 10.1002/14651858.CD007753.pub2. Pain Relief Review
21249697 There was an improvement in pain relief from acupuncture compared with a placebo control (OR 9.5, 95% CI 21.17 to 51.8), NSAIDs (SMD -0.70, 95% CI -1.08 to -0.32) and Chinese herbs (SMD -1.34, 95% CI -1.74 to -0.95). Cochrane Database Syst Rev. 2011 Jan 19;(1):CD007854. doi: 10.1002/14651858.CD007854.pub2. Pain Relief Review
21249697 In two trials acupuncture reduced menstrual symptoms (for example nausea, back pain) compared with medication (OR 3.25, 95% CI 1.53 to 6.86); in one trial acupuncture reduced menstrual symptoms compared with Chinese herbs (OR 7.0, 95% CI 2.22, 22.06); and in one trial acupuncture improved quality of life compared with usual care.There was an improvement in pain relief from acupressure compared with a placebo control (SMD -0.99, 95% CI -1.48 to -0.49), and in one trial acupressure reduced menstrual symptoms compared with a placebo control (SMD -0.58, 95% CI -1.06 to -0.10). Cochrane Database Syst Rev. 2011 Jan 19;(1):CD007854. doi: 10.1002/14651858.CD007854.pub2. Pain Relief Nausea and Vomiting Review
22443026 Acupuncture-like Transcutaneous Electrical Nerve Stimulation (TENS) is used for pain relief. Acupunct Electrother Res. 2011;36(3-4):231-58. doi: 10.3727/036012911803634139. Pain Relief Review
22794702 Complementary medicine uses the practice of conventional medicine with complementary and alternative medicine such as using acupuncture for pain relief in addition to opioids. Allergy Asthma Proc. 2012 May-Jun;33 Suppl 1:100-102. doi: 10.2500/aap.2012.33.3562. Pain Relief Review
22964986 Acupuncture-induced pain relief and the human brain's default mode network - an extended view of central effects of acupuncture analgesia. Forsch Komplementmed. 2012;19(4):197-201. doi: 10.1159/000341928. Epub 2012 Aug 3. Pain Relief Review
23140059 1) ATP release in the stimulated acupoint area is one of the key factors for producing acupuncture analgesia; 2) Acupuncture induced suppression of ATP activity in the central nervous system results in pain relief; 3) ATP application on the human body surface may strengthen the sensation propagation along the meridian; 4) Favorable regulation of acupuncture intervention on the abnormal functional activities of some viscera often accompanies with an increase of ATP content and ATPase activity in the related internal organs. Zhen Ci Yan Jiu. 2012 Aug;37(4):338-44. Pain Relief Review
23440796 Compared to conscious sedation alone, more effective pain relief was reported when conscious sedation was combined with electro-acupuncture: intra-operative pain mean difference (MD) on 1 to 10 visual analogue scale (VAS) of 3.00 (95% CI 2.23 to 3.77); post-operative pain MD in VAS units of 2.10 (95% CI 1.40 to 2.80; N = 61, one trial, low quality evidence); or paracervical block (MD not calculable).The pooled data of four trials showed a significantly lower intra-operative pain score with conscious sedation plus paracervical block than with electro-acupuncture plus paracervical block (MD on 10-point VAS of -0.66; 95% CI -0.93 to -0.39; N = 781, 4 trials, low quality evidence) with significant statistical heterogeneity (I(2) = 76%). Cochrane Database Syst Rev. 2013 Jan 31;(1):CD004829. doi: 10.1002/14651858.CD004829.pub3. Pain Relief Sedation Review
23650807 A large number of clinical trials and animal experiments have been carried out to focus on neurochemical mechanisms of acupuncture analgesia including postoperation pain relief, which may provide guidance for developing a novel clinical approach for postoperative analgesia. Zhen Ci Yan Jiu. 2013 Feb;38(1):83-7. Pain Relief Review
23904227 Low-quality evidence from single trials suggested that adding a rigid belt to exercise improved average pain but not function; acupuncture was significantly better than sham acupuncture for improving evening pain and function, but not average pain; and evening pain relief was the same following either deep or superficial acupuncture. Cochrane Database Syst Rev. 2013 Aug 1;(8):CD001139. doi: 10.1002/14651858.CD001139.pub3. Pain Relief Review
24284277 Acupuncture with therapeutic exercises is moderately recommended for pain relief, improving ROM and function. J Back Musculoskelet Rehabil. 2014;27(3):247-73. doi: 10.3233/BMR-130443. Pain Relief Review
25384448 Manual acupuncture is effective in short-term pain relief for the treatment of lateral epicondylalgia; however, its long-term analgesic effect is unremarkable. Am J Chin Med. 2014;42(6):1301-14. doi: 10.1142/S0192415X14500815. Analgesic Effect Pain Relief Review
2568074 Beneficial effects of external Qi Gong treatment given by a Qi Gong practitioner 1 to 3 times for 10-20 seconds each (although most Qi Gong masters take 3-20 minutes per treatment) often resulted in improvement of circulation and lowering of high blood pressure, as well as relaxation of spastic muscles, relief of pain, and enhanced general well-being, all of which resemble acupuncture effects. Acupunct Electrother Res. 1989;14(1):61-89. doi: 10.3727/036012989816358506. Pain Relief Blood Pressure Circulation Review
25690699 Acupuncture points stimulation is increasingly used for pain relief for CMP. Eur J Pain. 2015 Oct;19(9):1232-47. doi: 10.1002/ejp.671. Epub 2015 Feb 17. Pain Relief Review
25704563 Acupuncture, one of the most popular complementary therapies, is best known for its ability to provide pain relief. J Affect Disord. 2015 May 1;176:106-17. doi: 10.1016/j.jad.2015.01.048. Epub 2015 Jan 28. Pain Relief Review
26433798 Acupressure showed evidence of pain relief while acupuncture improved both the mental and the physical components of quality of life. J Acupunct Meridian Stud. 2015 Oct;8(5):220-8. doi: 10.1016/j.jams.2015.06.010. Epub 2015 Jun 20. Pain Relief Review
26484723 CONCLUSION: Perioperative acupuncture may provide pain relief without side effects in patients undergoing tonsillectomy. Laryngoscope. 2016 Mar;126(3):608-15. doi: 10.1002/lary.25721. Epub 2015 Oct 20. Pain Relief Side Effects Review
27145001 OBJECTIVES: To determine the effects of acupuncture for adults with neck pain, with focus on pain relief, disability or functional measures, patient satisfaction and global perceived effect. Cochrane Database Syst Rev. 2016 May 4;(5):CD004870. doi: 10.1002/14651858.CD004870.pub4. Pain Relief Review
27618609 The acupuncture method is based on influencing the body functions in a precise way by controlled irritation of particular active meridian points using special needles, heat (moxibustion), pressure (acupressure), underpressure (cupping), electricity (electroacupuncture), light (laser therapy), ultrasound (sonopuncture), static or pulsating electromagnetic field (magnetic therapy) and solutions (pharmacopuncture).The use of acupuncture as a method of pain relief in Modern Western Medicine is based on a wide range of clinical trials, and there is no doubt that it has significant effect in the treatment of acute and chronic pain classification. Neuro Endocrinol Lett. 2016 Jul;37(3):163-168. Pain Relief Review
28214637 BACKGROUND: Acupuncture anesthesia originated from the pain relief and pain prevention theory in acupuncture and moxibustion. World Neurosurg. 2017 Jun;102:623-631. doi: 10.1016/j.wneu.2017.02.036. Epub 2017 Feb 15. Pain Relief Review
28219657 Non-pharmacological treatments for pain relief: TENS and acupuncture. Joint Bone Spine. 2017 Dec;84(6):657-661. doi: 10.1016/j.jbspin.2017.02.005. Epub 2017 Feb 20. Pain Relief Review
28384564 We conducted a meta-analysis of randomized controlled trials (RCTs) to evaluate the effectiveness of acupuncture in pain relief in AIA. Breast. 2017 Jun;33:132-138. doi: 10.1016/j.breast.2017.03.015. Epub 2017 Apr 4. Pain Relief Review
28395101 Ear Acupuncture for Immediate Pain Relief-A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Pain Med. 2017 Mar 1;18(3):551-564. doi: 10.1093/pm/pnw215. Pain Relief Review
28395101 OBJECTIVE: To systematically review the literature on the effectiveness of ear acupuncture (EA) for immediate pain relief. Pain Med. 2017 Mar 1;18(3):551-564. doi: 10.1093/pm/pnw215. Pain Relief Review
29019640 Acupuncture can be an effective alternative and specific herbal supplements may provide short-term pain relief. FP Essent. 2017 Oct;461:15-20. Pain Relief Review
29231558 The effects of deqi (arrival of qi) on acupoint effects in patients with primary dysmenorrhea (PD) were evaluated.Ten literature databases,including China National Knowledge Infrastructure (CNKI),VIP Database,Wanfang Database,Chinese Biomedical Literature Database (CBM),Cochrane Library CENTRAL,MEDLINE,Embase,AMED, CINAHL Plus,PsycINFO were selected.In addition,5 registers of ongoing trials,the reference lists of included articles and grey literature website OpenGrey were added.The search time was from date of database establishment to August 2016;no restrictions were made on language or status of publication.All randomized controlled trials (RCTs) and quasi-randomized controlled trials (q-RCTs) which compared the effects of deqi and non-deqi on PD or compared the effects of different deqi elements on PD were included.The research quality was assessed according to Cochrane bias risk evaluation tool 5.1.0.The RevMan 5.3.5 was applied for quantitative analysis if insignificant clinical heterogenicity with I(2) anxiety regardless of deqi,and the effects of deqi on pain relief were superior or equivalent to that of none-deqi,and the effects of deqi on anxiety relief were similar to that of none-deqi;2 in circle the more intensity of deqi and higher number of acupoints selected,the better effects on pain alleviation,symptom relief and pain duration;3 in circle the higher rate of deqi had a better acupoint effect on alleviating anxiety,but was not on pain relief;4 in circle deqi appeared early and propagated to affected area could lead to faster onset on pain relief;⑤ the effects on relieving pain and symptoms was better when warm sensation in deqi or qi reaching affected area.Due to the few number,low quality and potential bias of included studies,it was not sufficient to draw clear conclusion regarding the effects of deqi on PD patients.This study protocol was registered in PROSPERO (CRD42016038518). Zhongguo Zhen Jiu. 2017 Jul 12;37(7):791-797. doi: 10.13703/j.0255-2930.2017.07.027. Pain Relief Anxiety Review
30232847 Furthermore, the mechanisms underlying reciprocal actions of neurotransmitters, neuromodulators and their receptors complicated in acupuncture-induced relief of pain affection in the higher brain regions also need to be explored further. Zhen Ci Yan Jiu. 2018 Aug 25;43(8):467-75. doi: 10.13702/j.1000-0607.180196. Pain Relief Review
30569405 CONCLUSIONS: Evidence suggests that acupuncture interventions may have a positive effect in pain relief, physical function and HRQoL in RA patients. Chin J Integr Med. 2019 Sep;25(9):704-709. doi: 10.1007/s11655-018-2914-x. Epub 2018 Dec 19. Pain Relief Review
31259837 BACKGROUND: Acupuncture, a key component of traditional Chinese medicine, is a form of alternative medicine in which thin needles are inserted into the body commonly for pain relief. J Chin Med Assoc. 2019 Sep;82(9):719-726. doi: 10.1097/JCMA.0000000000000140. Pain Relief Review
31271300 CONCLUSION: The effect of acupuncture may be associated with dose of acupuncture, with a higher dosage related to better treatment outcomes in terms of relief of pain and dysfunction in patients with knee osteoarthritis. Acupunct Med. 2019 Oct;37(5):261-267. doi: 10.1136/acupmed-2017-011608. Epub 2019 Jul 4. Pain Relief Review
31556315 Triple treatment of acupuncture, magnetic spectrum heat lamp and splinting showed stronger pain relief than splinting alone. Clin Rehabil. 2020 Jan;34(1):34-44. doi: 10.1177/0269215519877511. Epub 2019 Sep 26. Pain Relief Review
31690401 Complementary medicine involves diverse practices or products that are used with the practice of conventional medicine, such as using acupuncture in addition to opioids for pain relief. Allergy Asthma Proc. 2019 Nov 1;40(6):490-493. doi: 10.2500/aap.2019.40.4278. Pain Relief Review
31765838 They explain the effects of acupuncture in pain relief; few studies have been conducted concerning the conduction based on biophotons. J Acupunct Meridian Stud. 2020 Feb;13(1):1-11. doi: 10.1016/j.jams.2019.11.003. Epub 2019 Nov 23. Pain Relief Review
31877002 Acupuncture has been used for pain relief for thousands of years in China and may be a credible alternative to pharmacological treatments for people experiencing chronic pain, particularly when they are non-responsive or intolerant of usual care, or even want to avoid pharmacological treatment. Pain Relief Review
32379643 The result showed that moxibustion plus other active treatments (including western medicine, massage, acupuncture and core stability training) had better effects on low back pain relief compared with active treatments alone. Complement Ther Clin Pract. 2020 May;39:101130. doi: 10.1016/j.ctcp.2020.101130. Epub 2020 Feb 29. Pain Relief Review
32430505 More research is needed to establish if embedded needles at the ear are even necessary or have any advantage over in-session auricular acupuncture for immediate pain relief followed by ear acupressure. Pain Med. 2020 Jun 1;21(6):1276-1293. doi: 10.1093/pm/pnz379. Pain Relief Review
32458717 The results showed that acupuncture was more effective at inducing pain relief than: no treatment (standardised mean difference (SMD) -0.69, 95% CI -0.99 to -0.38); sham acupuncture in the immediate term (SMD -0.33, 95% CI -0.49 to -0.18), short term (SMD -0.47, 95% CI -0.77 to -0.17), and intermediate term (SMD -0.17, 95% CI -0.28 to -0.05); and usual care in the short term (SMD -1.07, 95% CI -1.81 to -0.33) and intermediate term (SMD -0.43, 95% CI -0.77 to -0.10). Acupunct Med. 2020 Aug;38(4):235-243. doi: 10.1136/acupmed-2017-011622. Epub 2020 May 27. Pain Relief Review
32533885 Moreover a lower baseline pain intensity and the location of low back pain resulted in a lower pain relief of acupuncture intervention. Eur J Pain. 2020 Oct;24(9):1653-1665. doi: 10.1002/ejp.1617. Epub 2020 Jul 31. Pain Relief Review
33004170 Acupuncture is efficacious for reducing pain in patients with LBP, and for short-term pain relief for those with neck pain. Best Pract Res Clin Anaesthesiol. 2020 Sep;34(3):603-616. doi: 10.1016/j.bpa.2020.08.005. Epub 2020 Aug 8. Pain Relief Review
33300479 Acupuncture for Cancer Pain - An Adjuvant Therapy for Cancer Pain Relief. Am J Chin Med. 2020;48(8):1769-1786. doi: 10.1142/S0192415X20500883. Epub 2020 Dec 9. Cancer Pain Pain Relief Review
33300479 As current pain management methods cannot effectively control pain among cancer patients, acupuncture has developed as an adjuvant therapy for cancer pain relief. Am J Chin Med. 2020;48(8):1769-1786. doi: 10.1142/S0192415X20500883. Epub 2020 Dec 9. Cancer Pain Pain Relief Review
34152398 The meta-analysis results indicated that acupuncture had a statistically significant influence on pain relief (standardized mean difference = -0.705, 95% CI -1.027 to -0.382, P = 0.000). Pain Med. 2021 Sep 8;22(9):2117-2127. doi: 10.1093/pm/pnab201. Pain Relief Review
34609377 Four of the 5 trials testing acupuncture offered favorable evidence of pain relief. J Oral Facial Pain Headache. 2021 Summer;35(3):175-198. doi: 10.11607/ofph.2868. Pain Relief Review
35248259 Does acupuncture provide pain relief in patients with osteoarthritis knee? An overview of systematic reviews. J Bodyw Mov Ther. 2022 Jan;29:117-126. doi: 10.1016/j.jbmt.2021.10.012. Epub 2021 Nov 2. Pain Relief Review
35248259 The application of acupuncture, as a method of complementary intervention, could be beneficial for pain relief and knee function in patients with knee OA. J Bodyw Mov Ther. 2022 Jan;29:117-126. doi: 10.1016/j.jbmt.2021.10.012. Epub 2021 Nov 2. Pain Relief Review
35249352 DISCUSSIONS: Compared to Western medicine treatments, acupuncture had a better effect on HZ, reduced the posterior neuralgia rate of patients, and shortened the course of treatment, but had no obvious effect on the relief of pain. Ann Palliat Med. 2022 Feb;11(2):756-765. doi: 10.21037/apm-22-109. Neuralgia Pain Relief Review
35695033 In terms of pain relief and improved CIPN-specific quality of life, acupuncture plus standard care was better than standard care alone. Acupunct Med. 2023 Apr;41(2):73-85. doi: 10.1177/09645284221076512. Epub 2022 Jun 12. Pain Relief Review
36804816 This review aims to evaluate the current evidence for acupuncture in endodontics and its potential role in emergency pain relief and management for patients. J Acupunct Meridian Stud. 2023 Feb 28;16(1):1-10. doi: 10.51507/j.jams.2023.16.1.1. Pain Relief Review
37005099 Methods such as relaxation techniques (ie, yoga, hypnosis, and music), manual techniques (ie, massage, reflexology, and shiatsu), acupuncture, birthing ball, and transcutaneous electrical nerve stimulation are considered safe, although the evidence supporting their effectiveness for pain relief is not as robust as it is for pharmacologic agents. Am J Obstet Gynecol. 2023 May;228(5S):S1246-S1259. doi: 10.1016/j.ajog.2023.03.003. Epub 2023 Mar 20. Pain Relief Review
37036917 Acupuncture involves treatment with the careful placement and manipulation (manually or using electricity) of needles to promote pain relief. Pain Relief Review
3909406 Five studies claim that acupuncture treatments give significant pain relief. Semin Arthritis Rheum. 1985 May;14(4):225-31. doi: 10.1016/0049-0172(85)90041-1. Pain Relief Review
6362392 The discovery of beta-endorphin in support of acupuncture pain relief is discussed. Am J Chin Med. 1983;11(1-4):150-8. doi: 10.1142/S0192415X83000252. Pain Relief Review
69288 These properties of trigger points--their widespread distribution and the pain relief produced by stimulating them--resemble those of acupuncture points for the relief of pain. Pain. 1977 Feb;3(1):3-23. doi: 10.1016/0304-3959(77)90032-X. Pain Relief Review
9395694 The association between acupuncture (AP) and pain relief is so strong that it has tended to obscure any other potentially significant clinical results. J Altern Complement Med. 1997 Spring;3(1):55-76. doi: 10.1089/acm.1997.3.55. Pain Relief Review
17587446 Within 4 weeks of the commencement of treatment manual acupuncture, static magnets and ultrasound therapies did not offer statistically significant short-term pain relief over placebo. BMC Musculoskelet Disord. 2007 Jun 22;8:51. doi: 10.1186/1471-2474-8-51. Pain Relief Review
19370680 The single study (including 90 women) examining TENS to acupuncture points and measuring satisfaction with pain relief reported that women in the TENS group were more satisfied with their pain relief compared with women in the control group (who received no pain relief whatsoever) (RR 4.10, 95% CI 1.81 to 9.29), Analysis 1.3. Cochrane Database Syst Rev. 2009 Apr 15;(2):CD007214. doi: 10.1002/14651858.CD007214.pub2. Pain Relief Review
20363196 Both conventional acupuncture and EA have been used for a variety of ailments, particularly for the relief of pain. Auton Neurosci. 2010 Oct 28;157(1-2):31-7. doi: 10.1016/j.autneu.2010.03.007. Epub 2010 Apr 3. Pain Relief Review
23055010 The potential physiological effects of acupuncture on pain relief have been attributed to biochemical processes such as the release of endorphins into the limbic structures, subcortical areas and brain stem, mechanisms that are also present in placebo-induced analgesia. Curr Rheumatol Rep. 2012 Dec;14(6):589-97. doi: 10.1007/s11926-012-0295-x. Pain Relief Review
23055010 In addition, pain relief with acupuncture is also associated with patient expectations, beliefs and interactions with their acupuncturists. Curr Rheumatol Rep. 2012 Dec;14(6):589-97. doi: 10.1007/s11926-012-0295-x. Pain Relief Review
23055010 While acupuncture in TCM it has been used for the treatment of many disorders, in this review, we examine its use for pain relief in musculoskeletal diseases, which are mostly chronic. Curr Rheumatol Rep. 2012 Dec;14(6):589-97. doi: 10.1007/s11926-012-0295-x. Pain Relief Review
23111099 Three studies demonstrated no significant difference between acupuncture and minimal/sham acupuncture with no difference in pain relief or function over 6 to 12 months. J Orthop Surg Res. 2012 Oct 30;7:36. doi: 10.1186/1749-799X-7-36. Pain Relief Review
23111099 This review provides some evidence to support acupuncture is better than no treatment, and some forms of conventional therapy, in providing some pain relief. J Orthop Surg Res. 2012 Oct 30;7:36. doi: 10.1186/1749-799X-7-36. Pain Relief Review
23111099 The evidence from this review supports the theory that there is no significant difference between acupuncture and sham/ minimal acupuncture in providing pain relief and improvements in function. J Orthop Surg Res. 2012 Oct 30;7:36. doi: 10.1186/1749-799X-7-36. Pain Relief Review
23111099 There was no evidence from these studies to support acupuncture providing long term pain relief benefit with all significant differences in pain being at 8 weeks to 3 months follow up. J Orthop Surg Res. 2012 Oct 30;7:36. doi: 10.1186/1749-799X-7-36. Pain Relief Review
35313481 Interestingly, acupuncture may be the best option for pain relief when a patient cannot take NSAIDs or other analgesic medications, exerting analgesic effects even faster than medication. Evid Based Complement Alternat Med. 2022 Mar 12;2022:1451342. doi: 10.1155/2022/1451342. eCollection 2022. Analgesic Effect Pain Relief Review
35313481 found that the analgesic effect of acupuncture in urolithiasis-driven renal colic pain relief was superior to that of diclofenac and acetaminophen after ten minutes, and there was no significant difference in the analgesic effect of the three types of therapy after 120 minutes. Evid Based Complement Alternat Med. 2022 Mar 12;2022:1451342. doi: 10.1155/2022/1451342. eCollection 2022. Analgesic Effect Pain Relief Kidney Review
35313481 For patients who cannot use NSAIDs or other analgesics, acupuncture can be an effective alternative for better pain relief. Evid Based Complement Alternat Med. 2022 Mar 12;2022:1451342. doi: 10.1155/2022/1451342. eCollection 2022. Pain Relief Review
23728665 Low quality evidence from one study (38 participants) showed a short-term benefit of acupuncture over antidepressants in pain relief: mean pain was 29 points (0 to 100 point scale) in the antidepressant group; acupuncture reduced pain by 17 points (95% CI −24.1 to −10.5). Cochrane Database Syst Rev. 2013 May 31;2013(5):CD007070. doi: 10.1002/14651858.CD007070.pub2. Pain Relief Review
23728665 One study examined acupuncture as an adjunct therapy to standard care comprising of a tricyclic antidepressant and exercise and found an additive effect of acupuncture for pain relief and reduction of muscle tenderness. Cochrane Database Syst Rev. 2013 May 31;2013(5):CD007070. doi: 10.1002/14651858.CD007070.pub2. Pain Relief Review
23728665 When considering acupuncture, electro-acupuncture could be an effective modality for short-term pain relief. Cochrane Database Syst Rev. 2013 May 31;2013(5):CD007070. doi: 10.1002/14651858.CD007070.pub2. Pain Relief Review
23728665 An analysis of data from four acupuncture trials totaling 864 participants concluded that there is a strong association between expectation and pain relief. Cochrane Database Syst Rev. 2013 May 31;2013(5):CD007070. doi: 10.1002/14651858.CD007070.pub2. Pain Relief Review
24322588 Acupuncture/electroacupuncture, used in China and other Asian countries for the past 3,000 yr, represents a potentially valuable adjunct to existing pain relief strategies. Anesthesiology. 2014 Feb;120(2):482-503. doi: 10.1097/ALN.0000000000000101. Pain Relief Review
24817897 This systematic review showed that acupuncture did not generate better effects on pain relief than drug therapy and sham acupuncture and that acupuncture plus drug therapy was better in managing cancer pain than drug therapy. Evid Based Complement Alternat Med. 2014;2014:170396. doi: 10.1155/2014/170396. Epub 2014 Apr 13. Cancer Pain Pain Relief Review
25132858 It means that WAA was superior to western medicine, sham acupuncture, or body acupuncture in pain relief. Evid Based Complement Alternat Med. 2014;2014:261709. doi: 10.1155/2014/261709. Epub 2014 Jul 15. Pain Relief Review
25132858 This indicated that the efficacy of WAA was superior to western medicine and sham acupuncture in pain relief. Evid Based Complement Alternat Med. 2014;2014:261709. doi: 10.1155/2014/261709. Epub 2014 Jul 15. Pain Relief Review
25165482 In terms of the efficacy of the different treatment methods, auricular acupressure boasts the largest strength of evidence for pain relief, followed by auricular acupuncture. Evid Based Complement Alternat Med. 2014;2014:934670. doi: 10.1155/2014/934670. Epub 2014 Jul 23. Pain Relief Review
25165482 In acupuncture, six treatments over a 3-week period provide better pain relief than does the administration of fewer than six treatments. Evid Based Complement Alternat Med. 2014;2014:934670. doi: 10.1155/2014/934670. Epub 2014 Jul 23. Pain Relief Review
25165482 Pain relief of auricular therapy using auricular acupuncture. Evid Based Complement Alternat Med. 2014;2014:934670. doi: 10.1155/2014/934670. Epub 2014 Jul 23. Pain Relief Review
25165482 Pain relief of auricular therapy using electroacupuncture stimulation. Evid Based Complement Alternat Med. 2014;2014:934670. doi: 10.1155/2014/934670. Epub 2014 Jul 23. Pain Relief Review
25254059 Acupuncture is gaining popularity in western medical culture as a tool for pain relief, and evidence is emerging concerning its potential mechanisms of action. Evid Based Complement Alternat Med. 2014;2014:850367. doi: 10.1155/2014/850367. Epub 2014 Sep 2. Pain Relief Review
25379462 Acupuncture (針灸 Zhēn Jiǔ) aims to treat a range of medical and dental ailments, though is most commonly used for pain relief. J Tradit Complement Med. 2014 Oct;4(4):218-23. doi: 10.4103/2225-4110.139113. Pain Relief Review
25614752 Accordingly, it is believed in TCM that acupuncture achieves its efficacy like pain relief via regulation of qi and blood and promotion of their circulation along the meridians. Evid Based Complement Alternat Med. 2014;2014:609594. doi: 10.1155/2014/609594. Epub 2014 Dec 29. Pain Relief Circulation Review
25821485 For chronic LBP, evidence consistently demonstrated that acupuncture provides short-term clinically relevant benefits for pain relief and functional improvement compared with no treatment or acupuncture plus another conventional intervention. Evid Based Complement Alternat Med. 2015;2015:328196. doi: 10.1155/2015/328196. Epub 2015 Mar 4. Pain Relief Review
25821485 Overall the analysis suggests that, (1) for acute LBP, there exists inconsistent evidence that acupuncture has a more favorable effect than sham acupuncture in relieving pain but consistent evidence that acupuncture does not significantly differ from sham acupuncture in improving function; (2) for chronic LBP, consistent evidence found that acupuncture provides short-term clinically relevant benefits on pain relief and functional improvement when compared with no treatment or when acupuncture is added to another conventional intervention; (3) for chronic LBP, it seems that genuine acupuncture produces a clinically significant reduction in pain when compared to sham acupuncture and sham therapy at short-term follow-up, but no impact on functional limitation. Evid Based Complement Alternat Med. 2015;2015:328196. doi: 10.1155/2015/328196. Epub 2015 Mar 4. Pain Relief Review
25821485 For chronic LBP, consistent evidence shows that acupuncture is more effective for pain relief and functional improvement at short-term follow-ups when compared to no treatment or when used with other conventional therapies; these results had medium to large clinical effects. Evid Based Complement Alternat Med. 2015;2015:328196. doi: 10.1155/2015/328196. Epub 2015 Mar 4. Pain Relief Review
25821485 Based on seven systematic reviews (two of high quality, three of moderate quality, and two of low quality), acupuncture is more clinically effective in pain relief and functional improvement than no treatment at short-term follow-up. Evid Based Complement Alternat Med. 2015;2015:328196. doi: 10.1155/2015/328196. Epub 2015 Mar 4. Pain Relief Review
26161404 Specifically, we included studies using either traditional anesthetic procedures or alternative medicine (acupuncture) for pain relief during ART and only trials that assessed IVF outcomes in terms of different parameters such us pregnancy rate, fertilization rate, number and quality of oocytes collected, embryo quality, and follicular levels of an anesthetic agent possibly related to toxicity. Biomed Res Int. 2015;2015:475362. doi: 10.1155/2015/475362. Epub 2015 Jun 16. Pain Relief Toxic Side Effects Review
26977172 However, as compared with the drug therapy alone, acupuncture plus drug therapy resulted in increased pain remission rate, shorter onset time of pain relief, longer pain-free duration, and better quality of life without serious adverse effects. Evid Based Complement Alternat Med. 2016;2016:1720239. doi: 10.1155/2016/1720239. Epub 2016 Feb 10. Pain Relief Adverse Reactions Review
26977172 In the past 20 years, many studies reported use of acupuncture for cancer pain relief. Evid Based Complement Alternat Med. 2016;2016:1720239. doi: 10.1155/2016/1720239. Epub 2016 Feb 10. Cancer Pain Pain Relief Review
26977172 A more recent review published in 2013 evaluated evidences from RCTs regarding use of acupuncture for cancer pain relief by meta-analysis, but only nine RCTs were included in their analysis. Evid Based Complement Alternat Med. 2016;2016:1720239. doi: 10.1155/2016/1720239. Epub 2016 Feb 10. Cancer Pain Pain Relief Review
26977172 Now with more and more newly published literatures, it is necessary to perform systematic review again on the use of acupuncture on cancer pain relief to update current knowledge and completely evaluate available experimental evidences in order to guide future research and practice. Evid Based Complement Alternat Med. 2016;2016:1720239. doi: 10.1155/2016/1720239. Epub 2016 Feb 10. Cancer Pain Pain Relief Review
26977172 The inclusion criteria were (1) study design: RCTs investigating the use of acupuncture for cancer pain relief that contain clinical data, regardless of publication status and language, (2) participants: adult patients diagnosed with any stage of cancer who experienced cancer pain, (3) intervention and control: acupuncture was used as the sole intervention or as an auxiliary therapy for other standard treatments for cancer pain, and a control group received standard treatments or placebo treatment. Evid Based Complement Alternat Med. 2016;2016:1720239. doi: 10.1155/2016/1720239. Epub 2016 Feb 10. Cancer Pain Pain Relief Review
26977172 If acupuncture plus conventional drug therapies was compared with conventional drug therapies alone, the use of analgesic drug must be unchanged during the study period, so as to ensure the effect of acupuncture on cancer pain relief clearly, and (4) outcome measures: the primary outcome was the analgesic effect validated with a pain measurement, such as the Visual Analog Scale for Pain (VAS Pain), the Numeric Rating Scale for Pain (NRS Pain), or the McGill Pain Questionnaire. Evid Based Complement Alternat Med. 2016;2016:1720239. doi: 10.1155/2016/1720239. Epub 2016 Feb 10. Analgesic Effect Cancer Pain Pain Relief Review
26977172 Our results showed that acupuncture treatment did not improve pain relief in any specific type of cancer patients in the subgroup analysis. Evid Based Complement Alternat Med. 2016;2016:1720239. doi: 10.1155/2016/1720239. Epub 2016 Feb 10. Pain Relief Review
26977172 The main findings were that compared with conventional drug therapy; acupuncture therapy alone did not show superior effects on cancer pain relief. Evid Based Complement Alternat Med. 2016;2016:1720239. doi: 10.1155/2016/1720239. Epub 2016 Feb 10. Cancer Pain Pain Relief Review
26977172 Acupuncture plus drug therapy resulted in increased remission rate of pain, shorter onset time of pain relief, longer duration of analgesic time, and better quality of life. Evid Based Complement Alternat Med. 2016;2016:1720239. doi: 10.1155/2016/1720239. Epub 2016 Feb 10. Pain Relief Review
26977172 As a result, we were unable to adequately assess the effectiveness and safety of acupuncture for cancer pain relief. Evid Based Complement Alternat Med. 2016;2016:1720239. doi: 10.1155/2016/1720239. Epub 2016 Feb 10. Cancer Pain Pain Relief Review
26977172 Although there were several systematic reviews of acupuncture for cancer pain relief, only the study by Choi et al. Evid Based Complement Alternat Med. 2016;2016:1720239. doi: 10.1155/2016/1720239. Epub 2016 Feb 10. Cancer Pain Pain Relief Review
26977172 Results of this systematic review suggested that compared with conventional drug therapy acupuncture alone did not show superior effects on pain relief. Evid Based Complement Alternat Med. 2016;2016:1720239. doi: 10.1155/2016/1720239. Epub 2016 Feb 10. Pain Relief Review
26977172 Acupuncture plus drug therapy resulted in increased remission rate of pain, shorter onset time of pain relief, longer duration of analgesia time, and better quality of life without serious adverse effects, as compared with drug therapy alone. Evid Based Complement Alternat Med. 2016;2016:1720239. doi: 10.1155/2016/1720239. Epub 2016 Feb 10. Pain Relief Adverse Reactions Review
26977172 However, the evidences available for this systematic review are insufficient to endorse a routine use of acupuncture for cancer pain relief because of the methodological limitations of the included studies. Evid Based Complement Alternat Med. 2016;2016:1720239. doi: 10.1155/2016/1720239. Epub 2016 Feb 10. Cancer Pain Pain Relief Review
26977172 The onset time of pain relief: acupuncture plus drug therapy versus drug therapy alone. Evid Based Complement Alternat Med. 2016;2016:1720239. doi: 10.1155/2016/1720239. Epub 2016 Feb 10. Pain Relief Review
26977172 The duration time of pain relief: acupuncture plus drug therapy versus drug therapy alone. Evid Based Complement Alternat Med. 2016;2016:1720239. doi: 10.1155/2016/1720239. Epub 2016 Feb 10. Pain Relief Review
27417472 One explanation is that since we do not know the exact mechanisms of pain relief of acupuncture, the sham controls, which involve active needle placement in alternate locations, are themselves having a therapeutic benefit. Children (Basel). 2014 Aug 21;1(2):134-48. doi: 10.3390/children1020134. Pain Relief Review
27471137 Acupuncture is commonly used for pain relief. Sci Rep. 2016 Jul 29;6:30675. doi: 10.1038/srep30675. Pain Relief Review
27471137 Therefore, these analyses suggested that real acupuncture had a greater effect on pain relief and disability improvement than did SA. Sci Rep. 2016 Jul 29;6:30675. doi: 10.1038/srep30675. Pain Relief Review
27471137 The real acupuncture showed a favorable effect on pain relief. Sci Rep. 2016 Jul 29;6:30675. doi: 10.1038/srep30675. Pain Relief Review
27471137 Based on currently available evidence, our meta-analysis found that, overall, acupuncture was superior to SA in terms of pain relief and disability reduction for patients with musculoskeletal disorders. Sci Rep. 2016 Jul 29;6:30675. doi: 10.1038/srep30675. Pain Relief Review
27471137 However, acupuncture was superior to SA for pain relief in only some of the individual conditions (chronic NP, SP, chronic LBP, OA, and MP). Sci Rep. 2016 Jul 29;6:30675. doi: 10.1038/srep30675. Pain Relief Review
27828892 Nonpharmacologic treatments that can be used with pain medications to improve pain relief include cryotherapy, distraction techniques, breathing and relaxation, and acupuncture. J Trauma Nurs. 2016 Nov/Dec;23(6):361-375. doi: 10.1097/JTN.0000000000000250. Pain Relief Review
28632194 In 2001, Battlefield Acupuncture, an auricular acupuncture procedure, was developed by Richard Niemtzow as a simple and effective method for rapid pain relief that can be performed with minimal training by non-licensed acupuncturists. Children (Basel). 2017 Jun 20;4(6):50. doi: 10.3390/children4060050. Pain Relief Review
28632194 A number of other articles have also shown some perceived pain relief without significant adverse effects due to acupuncture. Children (Basel). 2017 Jun 20;4(6):50. doi: 10.3390/children4060050. Pain Relief Adverse Reactions Review
29055360 The authors have found that use of adjunctive therapies, such as acupuncture may provide additional pain relief. Ophthalmology. 2017 Nov;124(11S):S34-S47. doi: 10.1016/j.ophtha.2017.08.004. Pain Relief Review
29080196 There is growing evidence from international groups showing that acupuncture induces NO-mediated vasodilatation, which increases local blood flow and allows for a flush of algesic or sensitizing substances, leading to pain relief. Chin J Integr Med. 2017 Nov;23(11):812-815. doi: 10.1007/s11655-017-2789-x. Epub 2017 Oct 28. Pain Relief Blood Flow Review
29080196 It is postulated that acupuncture stimulation improves local circulation and allows for a flush of algesic or sensitizing substances, leading to pain relief. Chin J Integr Med. 2017 Nov;23(11):812-815. doi: 10.1007/s11655-017-2789-x. Epub 2017 Oct 28. Pain Relief Circulation Review
29080196 Acupuncture induces an elevation of vasodilator (NO) release over skin regions, and elevated NO improves local circulation, which contribute to local warmness and the beneficial effects of acupuncture such as pain relief, improvements of sweating, and inflammation. Chin J Integr Med. 2017 Nov;23(11):812-815. doi: 10.1007/s11655-017-2789-x. Epub 2017 Oct 28. Pain Relief Circulation Review
29229658 One included acupuncture for pain relief along with other outcomes, while others discussed acupuncture and other Chinese medicine therapies for cancer care. BMJ Open. 2017 Dec 10;7(12):e018494. doi: 10.1136/bmjopen-2017-018494. Pain Relief Review
29234385 We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) on disease-related pain to critically evaluate the immediate effect of acupuncture for pain relief. Evid Based Complement Alternat Med. 2017;2017:3837194. doi: 10.1155/2017/3837194. Epub 2017 Oct 25. Pain Relief Review
29234385 Real acupuncture showed statistically significantly greater pain relief effect compared to sham acupuncture (SMD, −0.56; 95% confidence interval [CI], −1.00 to −0.12; 9 RCTs) and analgesic injection (SMD, −1.33; 95% CI, −1.94 to −0.72; 3 RCTs). Evid Based Complement Alternat Med. 2017;2017:3837194. doi: 10.1155/2017/3837194. Epub 2017 Oct 25. Pain Relief Review
29234385 Acupuncture was associated with a greater immediate pain relief effect compared to sham acupuncture and analgesic injections. Evid Based Complement Alternat Med. 2017;2017:3837194. doi: 10.1155/2017/3837194. Epub 2017 Oct 25. Pain Relief Review
29234385 Further RCTs with stricter design and methodologies are warranted to evaluate the immediate pain relief effect of acupuncture for more disease-related pain. Evid Based Complement Alternat Med. 2017;2017:3837194. doi: 10.1155/2017/3837194. Epub 2017 Oct 25. Pain Relief Review
29234385 To date, over 80 systematic reviews have been conducted to assess the role of acupuncture and related therapies in the relief of pain. Evid Based Complement Alternat Med. 2017;2017:3837194. doi: 10.1155/2017/3837194. Epub 2017 Oct 25. Pain Relief Review
29234385 The majority of the reviews reported positive results for pain relief in low back pain and osteoarthritis by acupuncture. Evid Based Complement Alternat Med. 2017;2017:3837194. doi: 10.1155/2017/3837194. Epub 2017 Oct 25. Pain Relief Review
29234385 Studies that met the following criteria were included in the present review: (1) randomized controlled clinical trials; (2) trials comparing acupuncture with sham acupuncture, no treatment, or effective western medications (e.g., anesthetics or analgesics); (3) studies including participants suffering from nonspecific pain; that is, there were no restrictions on the type, cause, or duration of pain; and (4) studies measuring self-reported pain relief using scales such as the visual analogue scale (VAS), numeric rating scale (NRS), or verbal rating scale (VRS). Evid Based Complement Alternat Med. 2017;2017:3837194. doi: 10.1155/2017/3837194. Epub 2017 Oct 25. Pain Relief Review
29234385 Real acupuncture showed a greater immediate pain relief effect compared to sham acupuncture (SMD, −0.56; 95% CI, −1.00 to −0.12; 9 RCTs, Figure 2). Evid Based Complement Alternat Med. 2017;2017:3837194. doi: 10.1155/2017/3837194. Epub 2017 Oct 25. Pain Relief Review
29234385 The results of the comparative efficacy studies revealed that acupuncture was associated with statistically significantly greater immediate pain relief compared to analgesic injection with nonsteroidal anti-inflammatory drugs (NSAIDs) or local anesthetic (SMD, −1.33; 95% CI, −1.94 to −0.72; 3 RCTs; Figure 3). Evid Based Complement Alternat Med. 2017;2017:3837194. doi: 10.1155/2017/3837194. Epub 2017 Oct 25. Pain Relief Review
29234385 Acupuncture was associated with statistically significantly greater immediate pain relief than no treatment (SMD, −1.63; 95% CI, 2.77 to −0.49; 1 RCT). Evid Based Complement Alternat Med. 2017;2017:3837194. doi: 10.1155/2017/3837194. Epub 2017 Oct 25. Pain Relief Review
29234385 Real acupuncture consistently showed a greater immediate pain relief effect compared to sham acupuncture and drug injection by excluding Zhang et al. Evid Based Complement Alternat Med. 2017;2017:3837194. doi: 10.1155/2017/3837194. Epub 2017 Oct 25. Pain Relief Review
29234385 After excluding the study by Zhang et al., subgroup meta-analysis showed that real acupuncture was better than penetrating sham in terms of the efficacy of pain relief (SMD, −0.75; 95% CI, −1.27 to −0.23; 4 RCTs, I2 = 75.8%, Figure 5), and acupuncture was more effective than the sham acupuncture in reducing acute pain (SMD, −1.08; 95% CI, −1.45 to −0.72; 2 RCTs, I2 = 0%, Figure 6). Evid Based Complement Alternat Med. 2017;2017:3837194. doi: 10.1155/2017/3837194. Epub 2017 Oct 25. Pain Relief Review
29234385 In present study, we did not find a greater immediate pain relief effect of acupuncture for acute pain compared with the sham acupuncture (P = 0.46). Evid Based Complement Alternat Med. 2017;2017:3837194. doi: 10.1155/2017/3837194. Epub 2017 Oct 25. Pain Relief Review
29234385 Based on the results of this systemic review and meta-analysis study, we found real acupuncture treatment has statistically significantly greater immediate pain relief than nonpenetrating sham acupuncture (SMD, −0.70; 95% CI, −1.21 to −0.20; 4 RCTs), but not these of penetrating sham acupuncture (SMD, −0.46; 95% CI, −1.11 to 0.18; 5 RCTs). Evid Based Complement Alternat Med. 2017;2017:3837194. doi: 10.1155/2017/3837194. Epub 2017 Oct 25. Pain Relief Review
29941854 The practice of acupuncture as pain relief is widely used in many of the countries throughout the world. Medicines (Basel). 2018 Jun 25;5(3):63. doi: 10.3390/medicines5030063. Pain Relief Review
29941854 Hurt and Zylka suggested that a longer period of pain relief might be achieved by injecting prostatic acid phosphatase (PAP) into the acupuncture points. Medicines (Basel). 2018 Jun 25;5(3):63. doi: 10.3390/medicines5030063. Pain Relief Review
30050856 Although pain relief is the most common use of acupuncture, numerous other conditions have been shown to improve with this therapy. Vet Med (Auckl). 2017 Aug 24;8:53-58. doi: 10.2147/VMRR.S125609. eCollection 2017. Pain Relief Review
30151019 Studies of acupuncture for anaesthesia or pain relief were excluded. Evid Based Complement Alternat Med. 2018 Jul 29;2018:3178472. doi: 10.1155/2018/3178472. eCollection 2018. Pain Relief Review
30298094 Acupuncture and Pain Relief Evid Based Complement Alternat Med. 2018 Sep 12;2018:8107508. doi: 10.1155/2018/8107508. eCollection 2018. Pain Relief Review
30298094 However, gate control theory cannot explain the full spectrum of acupuncture effects, and in particular the prolonged pain relief. Evid Based Complement Alternat Med. 2018 Sep 12;2018:8107508. doi: 10.1155/2018/8107508. eCollection 2018. Pain Relief Review
30584456 This overview has provided a summary of effects on pain relief and life quality among females with primary dysmenorrhea treated by acupuncture and acupressure therapies in five eligible SRs of RCTs. Evid Based Complement Alternat Med. 2018 Nov 21;2018:8791538. doi: 10.1155/2018/8791538. eCollection 2018. Pain Relief Review
30984277 Acupuncture served as an option to prevent the degeneration of cartilage and pain relief. Evid Based Complement Alternat Med. 2019 Mar 7;2019:6173412. doi: 10.1155/2019/6173412. eCollection 2019. Pain Relief Review
31105643 Conclusions: Acupuncture therapy seems effective for motor function, pain relief and activities of daily living in stroke patients with mild SHS, when it is used in combination with rehabilitation. Front Neurol. 2019 Apr 26;10:433. doi: 10.3389/fneur.2019.00433. eCollection 2019. Pain Relief Motor Function Review
31105643 However, two more recently published reviews suggested acupuncture might aid rehabilitation in several areas, including motor function recovery and pain relief. Front Neurol. 2019 Apr 26;10:433. doi: 10.3389/fneur.2019.00433. eCollection 2019. Pain Relief Motor Function Review
31186654 Acupuncture has been used to treat various pain disorders, including visceral pain, and has shown considerable effects on pain relief with only rare cases of adverse events. Evid Based Complement Alternat Med. 2019 May 2;2019:1304152. doi: 10.1155/2019/1304152. eCollection 2019. Visceral Pain Pain Relief Review
31186654 Many studies have explored the treatment mechanism of acupuncture for pain relief in general, and it is reported that acupuncture alleviates pain mainly by regulating the levels of endogenous opioids, serotonin, and norepinephrine and by inhibiting visceral nociceptors, inflammatory cytokines, and CNS activation. Evid Based Complement Alternat Med. 2019 May 2;2019:1304152. doi: 10.1155/2019/1304152. eCollection 2019. Pain Relief Review
31305415 Acupuncture as traditional oriental intervention is getting widely used and several systematic reviews (SRs) have reported the effectiveness of acupuncture on pain relief and functional recovery in patients with KOA. Medicine (Baltimore). 2019 Jul;98(28):e16301. doi: 10.1097/MD.0000000000016301. Pain Relief Review
31305415 Recently, several systematic reviews (SRs) have reported the efficacy of acupuncture on pain relief and functional recovery in patients with KOA. Medicine (Baltimore). 2019 Jul;98(28):e16301. doi: 10.1097/MD.0000000000016301. Pain Relief Review
31316572 Meanwhile, the National Academies of Sciences, Engineering, and Medicine (NASEM) pointed out that acupuncture has become common practice for pain relief in recent decades. Evid Based Complement Alternat Med. 2019 Jun 18;2019:5281039. doi: 10.1155/2019/5281039. eCollection 2019. Pain Relief Review
31316572 In addition, schedule related factors influencing pain relief during both acupuncture treatment and follow-up period were investigated. Evid Based Complement Alternat Med. 2019 Jun 18;2019:5281039. doi: 10.1155/2019/5281039. eCollection 2019. Pain Relief Review
31316572 In Figure 5(b), the higher DOSE of acupuncture did not guarantee better treatment pain relief. Evid Based Complement Alternat Med. 2019 Jun 18;2019:5281039. doi: 10.1155/2019/5281039. eCollection 2019. Pain Relief Review
31316572 The rate of pain relief increased slightly as the DOSE of acupuncture increased, peaked at the DOSE of 30 mins/week, and then declined steadily along the extending of DOSE. Evid Based Complement Alternat Med. 2019 Jun 18;2019:5281039. doi: 10.1155/2019/5281039. eCollection 2019. Pain Relief Review
31316572 In Figure 6(a), most of those 22 trials showed effective acupuncture; the pain relief percentage in 9 trials was beyond 20% (colored in green and blue), 15 trials above 10% (colored in yellow, green, and blue), 5 trials 1-10% (colored in orange), and 2 trials below 0% (colored in red). Evid Based Complement Alternat Med. 2019 Jun 18;2019:5281039. doi: 10.1155/2019/5281039. eCollection 2019. Pain Relief Review
31316572 In Figure 6(b), most of those 29 trials showed a long-term effective acupuncture; the pain relief percentage in 12 trials was beyond 20% (colored in bright yellow, green, and blue), 19 trials above 10% (colored in yellow, green, and blue), and 10 trials under 10% (colored in orange and red). Evid Based Complement Alternat Med. 2019 Jun 18;2019:5281039. doi: 10.1155/2019/5281039. eCollection 2019. Pain Relief Review
31316572 Relationship between acupuncture schedule related factors and pain relief rate. Evid Based Complement Alternat Med. 2019 Jun 18;2019:5281039. doi: 10.1155/2019/5281039. eCollection 2019. Pain Relief Review
31374032 There is a clinical basis for ear acupuncture, which may be effective for immediate pain relief, as well as psychiatric conditions such as substance abuse, insomnia, depression, and anxiety. Medicine (Baltimore). 2019 Aug;98(31):e16631. doi: 10.1097/MD.0000000000016631. Pain Relief Insomnia Anxiety Depression Review
31534469 When compared with a combination of simulation and improper location of needling, the effect of verum acupuncture for pain relief was the most obvious. Evid Based Complement Alternat Med. 2019 Aug 25;2019:8757685. doi: 10.1155/2019/8757685. eCollection 2019. Pain Relief Review
31534469 Verum acupuncture is more effective than sham acupuncture for pain relief, improving sleep quality, and reforming general status in FMS posttreatment. Evid Based Complement Alternat Med. 2019 Aug 25;2019:8757685. doi: 10.1155/2019/8757685. eCollection 2019. Pain Relief Sleep Quality Review
31534469 Two RCTs excluded from the meta-analysis showed that verum acupuncture alleviated pain, but its effect on pain relief was not significant in comparison with sham acupuncture because of the similar effects noted in sham acupuncture. Evid Based Complement Alternat Med. 2019 Aug 25;2019:8757685. doi: 10.1155/2019/8757685. eCollection 2019. Pain Relief Review
31534469 The evidence level of verum acupuncture's effect over sham acupuncture on pain relief was assessed as moderate. Evid Based Complement Alternat Med. 2019 Aug 25;2019:8757685. doi: 10.1155/2019/8757685. eCollection 2019. Pain Relief Review
31534469 Through this systematic review with meta-analysis, we found that verum acupuncture is more effective than sham acupuncture in the relief of pain, improvement of sleep quality, and recovery of general statuses in FMS posttreatment. Evid Based Complement Alternat Med. 2019 Aug 25;2019:8757685. doi: 10.1155/2019/8757685. eCollection 2019. Pain Relief Sleep Quality Review
31534469 It implies that verum acupuncture seems to be more effective in pain relief than sham acupuncture, but the true effect can be substantially different. Evid Based Complement Alternat Med. 2019 Aug 25;2019:8757685. doi: 10.1155/2019/8757685. eCollection 2019. Pain Relief Review
31534469 In the SA-IP type, the most obvious sham acupuncture, the effect on pain relief was the most significant and its evidence quality was high. Evid Based Complement Alternat Med. 2019 Aug 25;2019:8757685. doi: 10.1155/2019/8757685. eCollection 2019. Pain Relief Review
31534469 A study using a brain positron emission tomography technique showed that μ-opioid receptor-binding ability was stronger in verum acupuncture than in sham acupuncture even though there was no significant difference in clinical pain relief in both groups. Evid Based Complement Alternat Med. 2019 Aug 25;2019:8757685. doi: 10.1155/2019/8757685. eCollection 2019. Pain Relief Review
31781275 But the effect of laser acupuncture on pain relief was not maintained in terms of either VAS (p = 0.19) or WOMAC pain score (p = 0.60). Evid Based Complement Alternat Med. 2019 Nov 3;2019:6703828. doi: 10.1155/2019/6703828. eCollection 2019. Pain Relief Review
31781275 Primary Outcomes: Effects of Laser Acupuncture on Pain Relief Evid Based Complement Alternat Med. 2019 Nov 3;2019:6703828. doi: 10.1155/2019/6703828. eCollection 2019. Pain Relief Review
31781275 This study indicated that laser acupuncture only has the short-term effect for pain relief in terms of the VAS pain score, and this effect does not maintain for a long period; this finding is inconsistent with the conclusion from a previous meta-analysis, which reported that the effectiveness of laser acupuncture on the management of musculoskeletal pain tended to be more significant during long-term follow-up periods rather than at the end of intervention. Evid Based Complement Alternat Med. 2019 Nov 3;2019:6703828. doi: 10.1155/2019/6703828. eCollection 2019. Pain Relief Review
31855257 For example, a multicenter RCT of acupuncture published in 2018 found that patients with early-stage breast cancer who received aromatase inhibitor therapy experienced significant pain relief. JAMA Oncol. 2020 Feb 1;6(2):271-278. doi: 10.1001/jamaoncol.2019.5233. Pain Relief Review
32080154 There is also some clinical evidence of the effectiveness of ear acupuncture in psychiatric conditions such as substance abuse, insomnia, depression, and anxiety as well as immediate pain relief. Medicine (Baltimore). 2020 Feb;99(8):e19342. doi: 10.1097/MD.0000000000019342. Pain Relief Insomnia Anxiety Depression Review
32080154 Since immediate pain-relief effect of ear acupuncture has been well established in various pain conditions, the application of ear acupuncture may be considered in survivors with concurrent trauma-related problems and pain. Medicine (Baltimore). 2020 Feb;99(8):e19342. doi: 10.1097/MD.0000000000019342. Pain Relief Review
32493452 Of the various TOM treatments which include acupuncture, pharmacoacupuncture, acupotomy, and chuna (tuina) therapy, acupuncture has been reported to be better than drugs at treating occipital neuralgia in terms of pain relief and effective rate. BMC Complement Med Ther. 2020 Jun 3;20(1):171. doi: 10.1186/s12906-020-02955-y. Neuralgia Pain Relief Review
32714410 Acupuncture for DOMS exhibited very-small-to-small and small-to-moderate effects on pain relief for the sham and no acupuncture conditions, respectively. Evid Based Complement Alternat Med. 2020 Jun 27;2020:5864057. doi: 10.1155/2020/5864057. eCollection 2020. Pain Relief Review
32714410 Compared with sham acupuncture, the effects of pain relief from acupuncture on DOMS were very small to small, with nonsignificant differences between the two groups (P > 0.05). Evid Based Complement Alternat Med. 2020 Jun 27;2020:5864057. doi: 10.1155/2020/5864057. eCollection 2020. Pain Relief Review
32714410 The effect on pain relief of DOMS was in favour of acupuncture, and the meta-analysis on day 1 revealed that the acupuncture group had a moderate effect when compared to the control group (P < 0.05). Evid Based Complement Alternat Med. 2020 Jun 27;2020:5864057. doi: 10.1155/2020/5864057. eCollection 2020. Pain Relief Review
32714410 The acupuncture group also had small effect for DOMS pain relief on days 2 and 3, but there were no significant differences (P > 0.05). Evid Based Complement Alternat Med. 2020 Jun 27;2020:5864057. doi: 10.1155/2020/5864057. eCollection 2020. Pain Relief Review
32714410 However, the effects of acupuncture on pain relief for DOMS require further evidence. Evid Based Complement Alternat Med. 2020 Jun 27;2020:5864057. doi: 10.1155/2020/5864057. eCollection 2020. Pain Relief Review
32714410 It implies that acupuncture for DOMS seems to be used in pain relief at post-DOMS compared to nonuse of acupuncture. Evid Based Complement Alternat Med. 2020 Jun 27;2020:5864057. doi: 10.1155/2020/5864057. eCollection 2020. Pain Relief Review
32714410 Whilst the included studies demonstrated that the analgesic effect occurred during acupuncture treatment sessions after inducing DOMS, the very-small-small effect sizes found in the meta-analysis for pain relief limited our confidence on the benefits of acupuncture for DOMS. Evid Based Complement Alternat Med. 2020 Jun 27;2020:5864057. doi: 10.1155/2020/5864057. eCollection 2020. Analgesic Effect Pain Relief Review
32714410 However, the evidence on effects of pain relief for acupuncture was still weak in the current study because follow-up data of DOMS recovery were insufficient to perform a meta-analysis. Evid Based Complement Alternat Med. 2020 Jun 27;2020:5864057. doi: 10.1155/2020/5864057. eCollection 2020. Pain Relief Review
32714410 Our systematic review and meta-analysis revealed that acupuncture had very-small-to-small and small-to-moderate effects on pain relief for DOMS when compared with sham and no acupuncture, respectively. Evid Based Complement Alternat Med. 2020 Jun 27;2020:5864057. doi: 10.1155/2020/5864057. eCollection 2020. Pain Relief Review
32978666 The available evidence suggests that acupuncture does have short-term pain relief benefits for patients with symptomatic knee osteoarthritis and chronic low back pain and is a safe and reasonable referral option. Curr Rheumatol Rep. 2020 Sep 25;22(11):80. doi: 10.1007/s11926-020-00954-z. Pain Relief Review
32978666 However, evidence for the effectiveness of acupuncture for the relief of pain is inconsistent across a range of common musculoskeletal pain presentations. Curr Rheumatol Rep. 2020 Sep 25;22(11):80. doi: 10.1007/s11926-020-00954-z. Pain Relief Review
32978666 Overall, substantial evidence to date demonstrates that 6 or more session acupuncture treatment has short-term benefits for relief of pain for knee osteoarthritis when compared with western medicine or sham acupuncture. Curr Rheumatol Rep. 2020 Sep 25;22(11):80. doi: 10.1007/s11926-020-00954-z. Pain Relief Review
32978666 In the past five years, evidence from 7 overviews, summarizing about 300 randomized controlled trials, consistently demonstrated that acupuncture provides short-term clinically relevant benefits for pain relief and functional improvement when compared with sham or placebo, standard care or other types of controls (no treatment or acupuncture plus another conventional intervention). Curr Rheumatol Rep. 2020 Sep 25;22(11):80. doi: 10.1007/s11926-020-00954-z. Pain Relief Review
32978666 As a characteristic non-pharmaceutical option against the opioid crisis, acupuncture captured particularly concerning in back pain relief compared with other musculoskeletal conditions such as osteoarthritis, RA and fibromyalgia. Curr Rheumatol Rep. 2020 Sep 25;22(11):80. doi: 10.1007/s11926-020-00954-z. Pain Relief Review
32992601 In one study, 60 patients with knee osteoarthritis received BVA twice a week continued for 4 weeks, and BVA was proven to be more effective than traditional acupuncture for pain relief. Toxins (Basel). 2020 Sep 27;12(10):618. doi: 10.3390/toxins12100618. Pain Relief Review
33441387 Results indicated a favourable effect of acupuncture on pain relief in palliative care for patients with cancer. BMJ Support Palliat Care. 2021 Sep;11(3):264-270. doi: 10.1136/bmjspcare-2020-002638. Epub 2021 Jan 13. Pain Relief Review
33441387 A number of systematic reviews and meta-analyses have examined acupuncture for pain relief in patients with cancer. BMJ Support Palliat Care. 2021 Sep;11(3):264-270. doi: 10.1136/bmjspcare-2020-002638. Epub 2021 Jan 13. Pain Relief Review
33441387 The findings from these previous studies indicated that acupuncture might be effective and safe in providing pain relief in palliative care in patients with cancer. BMJ Support Palliat Care. 2021 Sep;11(3):264-270. doi: 10.1136/bmjspcare-2020-002638. Epub 2021 Jan 13. Pain Relief Review
33553202 However, the effect of acupuncture on pain relief may be mainly achieved within post-operative 48 h, and it had no efficacy in improving range of knee motion. Front Med (Lausanne). 2021 Jan 18;7:602564. doi: 10.3389/fmed.2020.602564. eCollection 2020. Pain Relief Review
33553202 Many previous studies suggested that acupuncture was a potential method for pain relief, and it was widely used for the treatment and rehabilitation of acute or chronic pain. Front Med (Lausanne). 2021 Jan 18;7:602564. doi: 10.3389/fmed.2020.602564. eCollection 2020. Pain Relief Review
33553202 Although acupuncture treatment exerted no positive effects on pain relief in the long stage and ROM of knee after TKA surgery, it achieved significant improvements in relieving the early post-operative pain and reducing the ratio of nausea/vomiting after TKA, which demonstrates that the use of acupuncture in the early post-operative period can be beneficial for the early post-operative rehabilitation. Front Med (Lausanne). 2021 Jan 18;7:602564. doi: 10.3389/fmed.2020.602564. eCollection 2020. Pain Relief Nausea and Vomiting Review
33584181 In addition, 5-HT in the dorsal raphe nucleus, opioid receptors in the cingulate cortex, and plasma met-enkephalin are involved in acupuncture relief of pain and psychological symptoms. Front Neurosci. 2021 Jan 27;14:626497. doi: 10.3389/fnins.2020.626497. eCollection 2020. Pain Relief Review
33584181 Moreover, in a study of the mechanism of acupuncture in fibromyalgia patients, the authors found that after acupuncture, a complex interaction might occur between the insula cortex and the anterior cingulate, which induced a relief of pain and improvement of emotional experience. Front Neurosci. 2021 Jan 27;14:626497. doi: 10.3389/fnins.2020.626497. eCollection 2020. Pain Relief Mood Review
33584181 Plasma met-enkephalin is involved in acupuncture relief of pain and psychiatric symptoms. Front Neurosci. 2021 Jan 27;14:626497. doi: 10.3389/fnins.2020.626497. eCollection 2020. Pain Relief Review
33584181 In addition, patients with a lower baseline plasma met-enkephalin concentration were more likely to get successful acupuncture pain relief. Front Neurosci. 2021 Jan 27;14:626497. doi: 10.3389/fnins.2020.626497. eCollection 2020. Pain Relief Review
33584181 It is generally known that acupuncture is a time-honored form of pain relief. Front Neurosci. 2021 Jan 27;14:626497. doi: 10.3389/fnins.2020.626497. eCollection 2020. Pain Relief Review
33586504 In addition, polymodal receptor hypothesis, purinergic signaling and other mechanotransduction-based responses to acupuncture may also contribute to pain relief. Integr Cancer Ther. 2021 Jan-Dec;20:1534735420980811. doi: 10.1177/1534735420980811. Pain Relief Review
33757500 Body acupuncture, as part of Traditional Chinese Medicine (TCM), has become increasingly used for pain relief worldwide, given its beneficial effects for treating pain and disability and provides a potential opportunity for integration into patient-centered care. BMC Complement Med Ther. 2021 Mar 23;21(1):101. doi: 10.1186/s12906-021-03272-8. Pain Relief Review
33757500 The aim of this scoping review was to identify clinical studies and reports on eye acupuncture with the aim of informing practitioners, patients and researchers about the use of this emerging intervention for pain relief. BMC Complement Med Ther. 2021 Mar 23;21(1):101. doi: 10.1186/s12906-021-03272-8. Pain Relief Review
33896475 There is some evidence from laboratory studies in rats that electroacupuncture may produce analgesia by activating endogenous opioids and opioid receptors in the brain, explaining a potential mechanism for both pain relief and reduced need for opioids. Semin Nephrol. 2021 Jan;41(1):68-81. doi: 10.1016/j.semnephrol.2021.02.007. Pain Relief Review
34093119 After sustained acupuncture treatment, the relief of pain intensity might be regulated by the DMN, FPN, limbic system and DPMS (Zhao et al.,; Li et al.,; Gu et al.,; Zou et al.,). Front Neurosci. 2021 May 20;15:674852. doi: 10.3389/fnins.2021.674852. eCollection 2021. Pain Relief Review
34178633 Likewise, this review also demonstrated that pain relief was obvious in patients receiving acupuncture compared with controls, and this improvement was multidimensional. Front Oncol. 2021 Jun 10;11:646315. doi: 10.3389/fonc.2021.646315. eCollection 2021. Pain Relief Review
34307076 The practice of acupuncture is becoming increasingly popular in veterinary medicine, especially as a method of providing pain relief. Open Vet J. 2021 Apr-Jun;11(2):203-209. doi: 10.5455/OVJ.2021.v11.i2.3. Epub 2021 Apr 15. Pain Relief Review
34307076 Electroacupuncture is considered the most effective type of acupuncture delivery, allowing for more potent and long-lasting pain relief than is achieved via other methods (e.g., dry needling). Open Vet J. 2021 Apr-Jun;11(2):203-209. doi: 10.5455/OVJ.2021.v11.i2.3. Epub 2021 Apr 15. Pain Relief Review
34307076 In addition to these investigations, some of the clinical studies demonstrating acupuncture efficacy for pain relief have been conducted in companion animal species. Open Vet J. 2021 Apr-Jun;11(2):203-209. doi: 10.5455/OVJ.2021.v11.i2.3. Epub 2021 Apr 15. Pain Relief Review
34307076 Acupuncture induces several physiological effects peripherally which contribute to pain relief. Open Vet J. 2021 Apr-Jun;11(2):203-209. doi: 10.5455/OVJ.2021.v11.i2.3. Epub 2021 Apr 15. Pain Relief Review
34336626 The analysis also showed that acupuncture was better for pain relief than sham acupuncture. Anesth Pain Med. 2021 Apr 3;11(2):e113627. doi: 10.5812/aapm.113627. eCollection 2021 Apr. Pain Relief Review
34336626 Acupuncture added into the control group demonstrated greater pain relief in the studies with unclear allocation concealment (SMD -1.78, 95% CI: -2.08 - - 1.48). Anesth Pain Med. 2021 Apr 3;11(2):e113627. doi: 10.5812/aapm.113627. eCollection 2021 Apr. Pain Relief Review
34336626 However, when acupuncture was added into the control group in studies with good allocation concealment there was no significant pain relief (SMD - 0.07, 95% CI: -0.26 - 0.12). Anesth Pain Med. 2021 Apr 3;11(2):e113627. doi: 10.5812/aapm.113627. eCollection 2021 Apr. Pain Relief Review
34336626 The electroacupuncture versus the control or electroacupuncture plus the active control demonstrated significant pain relief. Anesth Pain Med. 2021 Apr 3;11(2):e113627. doi: 10.5812/aapm.113627. eCollection 2021 Apr. Pain Relief Review
34336626 The review concluded that acupuncture and conventional therapy demonstrated similar effects regarding pain relief and disability. Anesth Pain Med. 2021 Apr 3;11(2):e113627. doi: 10.5812/aapm.113627. eCollection 2021 Apr. Pain Relief Review
34336626 Pain relief was better when acupuncture was added onto conventional therapy, and electroacupuncture lessened pain to a greater degree. Anesth Pain Med. 2021 Apr 3;11(2):e113627. doi: 10.5812/aapm.113627. eCollection 2021 Apr. Pain Relief Review
34349826 The funnel chart analysis results of the main outcome indicators of the response rates of pain relief suggested that publication bias might exist and exaggerate the efficacy of acupuncture combined with three-step analgesic drugs in the treatment of cancer pain; see Figure 9. Evid Based Complement Alternat Med. 2021 Jul 26;2021:5558590. doi: 10.1155/2021/5558590. eCollection 2021. Cancer Pain Pain Relief Review
34349826 Based on the meta-analysis of 19 studies, compared with the treatment of cancer pain with three-step analgesic drug treatment alone, the response rates of pain relief from acupuncture combined with three-step analgesic drug treatment were higher, the NRS scores were lower, the incidence of adverse reactions such as nausea and vomiting was less frequent, the incidence of times of burst pain was also less frequent, the onset time to analgesic effect was shorter, and the duration of pain response was longer. Evid Based Complement Alternat Med. 2021 Jul 26;2021:5558590. doi: 10.1155/2021/5558590. eCollection 2021. Analgesic Effect Cancer Pain Pain Relief Adverse Reactions Nausea and Vomiting Review
34408622 Acupuncture, a complementary and alternative therapy, is widely used around the world and has been proven to provide substantial pain relief. Front Neurosci. 2021 Aug 2;15:695670. doi: 10.3389/fnins.2021.695670. eCollection 2021. Pain Relief Review
34408622 Of the patients receiving acupuncture treatment for pain relief, 41% have diseases involving inflammatory pain. Front Neurosci. 2021 Aug 2;15:695670. doi: 10.3389/fnins.2021.695670. eCollection 2021. Pain Relief Inflammatory Pain Review
34489662 found that acupoint and sham acupoint (away from the Meridians) showed a striking similarity in fMRI results, indicating that acupuncture is effective in pain relief regardless of the choice of point. Front Hum Neurosci. 2021 Aug 20;15:694919. doi: 10.3389/fnhum.2021.694919. eCollection 2021. Pain Relief Review
34521235 proposed that the cause of pain relief by acupuncture may be related to the increased connectivity between the precentral gyrus and middle frontal gyrus. Integr Cancer Ther. 2021 Jan-Dec;20:15347354211044107. doi: 10.1177/15347354211044107. Pain Relief Review
34526816 To obtain evidence-based conclusions about the effect of acupuncture on pain relief in women undergoing oocyte retrieval, the results of randomized controlled trials (RCTs) that met the criteria were assessed on the Pain Assessment Scale and pregnancy indicators. J Pain Res. 2021 Sep 9;14:2833-2849. doi: 10.2147/JPR.S319923. eCollection 2021. Pain Relief Review
34526816 Although previous systematic review demonstrated no evidence supporting acupuncture to be more optimal for pain relief during OPU than PCA with CSA, the updated Cochrane review supported acupuncture is appropriate to adjuvant analgesia OPU process. J Pain Res. 2021 Sep 9;14:2833-2849. doi: 10.2147/JPR.S319923. eCollection 2021. Pain Relief Review
34526816 This review would include randomized controlled trials (RCTs) on acupuncture for pain relief during OPU to conduct a systematic review and meta-analysis of the relevant studies. J Pain Res. 2021 Sep 9;14:2833-2849. doi: 10.2147/JPR.S319923. eCollection 2021. Pain Relief Review
34526816 It aimed to evaluate acupuncture for pain relief during OPU in an evidence-based perspective and provided recommendations for acupuncture clinical analgesia. J Pain Res. 2021 Sep 9;14:2833-2849. doi: 10.2147/JPR.S319923. eCollection 2021. Pain Relief Review
34526816 Acupuncture compound pharmacological anesthesia, which is more effective than a single form of pain relief, is worth promoting and safe. J Pain Res. 2021 Sep 9;14:2833-2849. doi: 10.2147/JPR.S319923. eCollection 2021. Pain Relief Review
34629905 Patients received opioids and acupuncture for pain relief with the central outcome assessment of pain and other side effects. Clin Epidemiol. 2021 Oct 2;13:907-919. doi: 10.2147/CLEP.S324193. eCollection 2021. Pain Relief Side Effects Review
34658755 Past studies have shown the relief of pain in response to acupuncture therapy as compared with the sham acupuncture or control groups. Front Neurosci. 2021 Sep 28;15:696843. doi: 10.3389/fnins.2021.696843. eCollection 2021. Pain Relief Review
34667434 Acupuncture in combination with standard pharmacotherapy reduced the onset time of pain relief and prolonged duration of analgesic effect in comparison to pharmacotherapy alone. Contemp Oncol (Pozn). 2021;25(2):88-94. doi: 10.5114/wo.2021.105969. Epub 2021 May 7. Analgesic Effect Pain Relief Review
34828543 Although electroacupuncture (EA) is an effective treatment for pain relief, there has been no systematic review of EA treatment for temporomandibular disorder TMD. Healthcare (Basel). 2021 Nov 2;9(11):1497. doi: 10.3390/healthcare9111497. Pain Relief Review
34828543 Electroacupuncture (EA), which combines manual acupuncture with an electric stimulus, is a common treatment method for musculoskeletal diseases and injuries and is more effective for pain relief than manual acupuncture. Healthcare (Basel). 2021 Nov 2;9(11):1497. doi: 10.3390/healthcare9111497. Pain Relief Review
34889286 Until now, acupuncture was commonly used for CP and chronic pain relief in eastern countries. Medicine (Baltimore). 2021 Dec 10;100(49):e28163. doi: 10.1097/MD.0000000000028163. Pain Relief Review
35222677 CHM and acupuncture demonstrate more benefits than drugs in pain relief, cure rate improvement, and incidence reduction of PHN. Evid Based Complement Alternat Med. 2022 Feb 18;2022:8674648. doi: 10.1155/2022/8674648. eCollection 2022. Pain Relief Review
35313481 Interestingly, acupuncture may be the best option for pain relief when a patient cannot take NSAIDs or other analgesic medications, exerting analgesic effects even faster than medication. Evid Based Complement Alternat Med. 2022 Mar 12;2022:1451342. doi: 10.1155/2022/1451342. eCollection 2022. Analgesic Effect Pain Relief Review
35313481 found that the analgesic effect of acupuncture in urolithiasis-driven renal colic pain relief was superior to that of diclofenac and acetaminophen after ten minutes, and there was no significant difference in the analgesic effect of the three types of therapy after 120 minutes. Evid Based Complement Alternat Med. 2022 Mar 12;2022:1451342. doi: 10.1155/2022/1451342. eCollection 2022. Analgesic Effect Pain Relief Kidney Review
35313481 For patients who cannot use NSAIDs or other analgesics, acupuncture can be an effective alternative for better pain relief. Evid Based Complement Alternat Med. 2022 Mar 12;2022:1451342. doi: 10.1155/2022/1451342. eCollection 2022. Pain Relief Review
35380733 The immediate analgesia from a single acupuncture treatment provides better pain relief than does sham or analgesic injection, making acupuncture especially beneficial for acute pain, with opioid-sparing potential in hospital settings. Pain Med. 2022 Aug 31;23(9):1582-1612. doi: 10.1093/pm/pnac056. Pain Relief Review
35380733 An SRM of auricular acupuncture for acute and postsurgical pain found that it provided immediate pain relief and benefit at 48 hours, was equivalent to analgesics, and had fewer side effects. Pain Med. 2022 Aug 31;23(9):1582-1612. doi: 10.1093/pm/pnac056. Pain Relief Side Effects Review
35380733 One SRM included 19 RCTs and 11 observational studies and reported that acupuncture provided effective analgesia for most acute pain conditions in the ED while being noninferior to selected analgesia medications and providing statistically significant, clinically meaningful, and improved levels of patient satisfaction with respect to pain relief in the emergency setting. Pain Med. 2022 Aug 31;23(9):1582-1612. doi: 10.1093/pm/pnac056. Pain Relief Review
35380733 Another ED trial used an abbreviated 10-minute acupuncture treatment for acute LBP with usual care vs usual care alone, finding no difference in pain relief. Pain Med. 2022 Aug 31;23(9):1582-1612. doi: 10.1093/pm/pnac056. Pain Relief Review
35449821 Acupuncture can also achieve postoperative pain relief and decreased consumption of opioids. Evid Based Complement Alternat Med. 2022 Apr 11;2022:7705256. doi: 10.1155/2022/7705256. eCollection 2022. Pain Relief Review
35496051 Acupuncture has beneficial effect on pain relief and improves function activities, and this treatment can be recommended as a beneficial alternative therapy in patients with KOA, particularly for chronic patients and those currently undergoing long-term pain and help them increasing quality of life. Biomed Res Int. 2022 Apr 21;2022:6561633. doi: 10.1155/2022/6561633. eCollection 2022. Pain Relief Review
35570887 Based on the consideration of the number of points needled during each treatment; de qi response; frequency of treatment per week; and several treatment sessions, the study found out that the effect may be associated with the dose of acupuncture, with a higher dosage (the number of points needled ≥9; de qi response; frequency ≥2 sessions a week; the total number of treatment sessions ≥8) related to better treatment outcomes in terms of relief of pain and dysfunction in patients with knee osteoarthritis. Front Public Health. 2022 Apr 28;10:858587. doi: 10.3389/fpubh.2022.858587. eCollection 2022. Pain Relief Review
35586692 Many in vivo studies have shown that neuropeptides are critical for the central control of male sexuality and are involved in pain relief mechanisms after acupuncture. Evid Based Complement Alternat Med. 2022 May 9;2022:4807271. doi: 10.1155/2022/4807271. eCollection 2022. Pain Relief Review
35725779 Similarly, in a recent meta-analysis by Li et al (2021) including 19 articles (N= 1502 patients), in which the efficacy and safety of acupuncture combined with the WHO three-step analgesic drug ladder for cancer pain was studied, addition of acupuncture to the drug ladder increased pain relief response rates (relative risk/risk ratio (RR) = 1.12, 95% CI: 1.08 to 1.17), reduced NRS score (standard mean difference (SMD) = −1.10, 95% CI: −1.86 to −0.35, ), reduced the rate of side effects (RR = 0.45, 95% CI: 0.38 to 0.53, ), reduced the burst pain rate (SMD = −1.38; 95% CI: −2.44 to −0.32, ), shortened analgesia effect onset time, and extended the duration of response. Blood Rev. 2022 Nov;56:100985. doi: 10.1016/j.blre.2022.100985. Epub 2022 Jun 13. Cancer Pain Pain Relief Side Effects Review
35737304 The use of veterinary acupuncture for pain relief is expanding among small animal practitioners. Vet Sci. 2022 May 26;9(6):252. doi: 10.3390/vetsci9060252. Pain Relief Review
35737304 It is a highly effective method to treat pain.. The use of veterinary acupuncture for pain relief is expanding among small animal practitioners. Vet Sci. 2022 May 26;9(6):252. doi: 10.3390/vetsci9060252. Pain Relief Review
35737304 Of these roughly 4000 papers, 41% are focused on acupuncture for analgesia or pain relief and the majority concerned humans or laboratory animals. Vet Sci. 2022 May 26;9(6):252. doi: 10.3390/vetsci9060252. Pain Relief Review
35737304 The segmental effects of acupuncture can provide pain relief, improve circulation and healing, and increase mobilization. Vet Sci. 2022 May 26;9(6):252. doi: 10.3390/vetsci9060252. Pain Relief Circulation Review
35737304 When this area, as well as the muscles around the stifle are treated with dry needle acupuncture (DN), the stifle experiences significant pain relief. Vet Sci. 2022 May 26;9(6):252. doi: 10.3390/vetsci9060252. Pain Relief Review
35832526 Studies in recent years have shown that the acupuncture treatment of acute renal colic caused by urinary calculi has rapid pain relief, reliable curative effect, and no toxic side effects, but the sample sizes of these trials were small, and their conclusions were seen as overly positive. Evid Based Complement Alternat Med. 2022 Jul 4;2022:7140038. doi: 10.1155/2022/7140038. eCollection 2022. Pain Relief Toxic Side Effects Side Effects Kidney Review
35832526 At present, over 80 systematic reviews have been conducted to assess the role of acupuncture and related therapies in the relief of pain; however, the results of these systematic reviews are far from unanimous, and there is no systematic evaluation of the efficacy and safety of manual acupuncture in the treatment of acute renal colic caused by urinary calculi in adults. Evid Based Complement Alternat Med. 2022 Jul 4;2022:7140038. doi: 10.1155/2022/7140038. eCollection 2022. Pain Relief Kidney Review
35832526 Low-certainty evidence indicates that there was no statistically significant difference between acupuncture as a monotherapy and the control group for the time of complete pain relief. Evid Based Complement Alternat Med. 2022 Jul 4;2022:7140038. doi: 10.1155/2022/7140038. eCollection 2022. Pain Relief Review
35832526 2 studies reported the time of complete pain relief, all of which used manual acupuncture as a monotherapy in the experimental group. Evid Based Complement Alternat Med. 2022 Jul 4;2022:7140038. doi: 10.1155/2022/7140038. eCollection 2022. Pain Relief Review
35884060 Acupuncture has long been studied as an effective method of pain relief, although the use of acupuncture in pediatric patients with SCD during an acute vaso-occlusive pain episode is vastly understudied. Children (Basel). 2022 Jul 19;9(7):1076. doi: 10.3390/children9071076. Pain Relief Review
35884060 Acupuncture has long been studied for pain relief, however, a unified theory of its action in Western Medicine has not been accepted. Children (Basel). 2022 Jul 19;9(7):1076. doi: 10.3390/children9071076. Pain Relief Review
35923845 References with highest frequency or centrality were both systematic evaluations focusing on different acupuncture therapies for postoperative pain relief. J Pain Res. 2022 Jul 27;15:2085-2104. doi: 10.2147/JPR.S371399. eCollection 2022. Pain Relief Review
35923845 In this study, the analysis of annual volume of publications and journals suggests that the field of acupuncture therapy for postoperative pain relief is currently in a period of rapid development. J Pain Res. 2022 Jul 27;15:2085-2104. doi: 10.2147/JPR.S371399. eCollection 2022. Pain Relief Review
35978992 The results also showed that acupuncture plus control treatment (compared with control treatment) was connected with relieving pain intensity, increasing the pain relief rate, reducing the frequency of breakthrough pain, shortening analgesic onset time, extending the analgesic duration, and improving the quality of life. Front Pain Res (Lausanne). 2022 Aug 1;3:925013. doi: 10.3389/fpain.2022.925013. eCollection 2022. Pain Relief Review
35978992 In terms of reference outcomes, eight studies reported a pain relief rate, one study measured the changes in the frequency of breakthrough pain, and two studies measured the analgesic onset time and analgesia duration after acupuncture treatments. Front Pain Res (Lausanne). 2022 Aug 1;3:925013. doi: 10.3389/fpain.2022.925013. eCollection 2022. Pain Relief Review
35978992 Two studies provide information on analgesic onset time to evaluate the effectiveness of acupuncture in pain relief. Front Pain Res (Lausanne). 2022 Aug 1;3:925013. doi: 10.3389/fpain.2022.925013. eCollection 2022. Pain Relief Review
35978992 This systematic review intends to make a comprehensive evaluation of the effectiveness of acupuncture on CIBP, not only assessing the pain score and pain relief rate, but also the frequency of breakthrough pain, analgesic onset time, and analgesic duration. Front Pain Res (Lausanne). 2022 Aug 1;3:925013. doi: 10.3389/fpain.2022.925013. eCollection 2022. Pain Relief Review
35978992 In addition, it significantly increased the pain relief rate, reduced the frequency of breakthrough pain, shortened analgesic onset time, and extended the analgesic duration when the control groups added acupuncture therapy. Front Pain Res (Lausanne). 2022 Aug 1;3:925013. doi: 10.3389/fpain.2022.925013. eCollection 2022. Pain Relief Review
35978992 The acupuncture prescriptions of the three studies were different, and researchers select ear points based on the sites of bone metastases; however, these studies chose the same ear point, ear Shenmen (TF4), which is a key point for pain relief. Front Pain Res (Lausanne). 2022 Aug 1;3:925013. doi: 10.3389/fpain.2022.925013. eCollection 2022. Pain Relief Review
36203799 The pain relief effects of acupuncture are also mediated by activity in the brain and spinal cord. Front Neurosci. 2022 Sep 20;16:940343. doi: 10.3389/fnins.2022.940343. eCollection 2022. Pain Relief Review
36203799 These studies clearly showed that acupuncture blocked multiple protein kinases activation to reduce spinal cord neuronal activity in painful conditions and achieved pain relief. Front Neurosci. 2022 Sep 20;16:940343. doi: 10.3389/fnins.2022.940343. eCollection 2022. Pain Relief Review
36203799 However, there are no reports of neuropathic pain relief by acupuncture mediated by 5-HT2A, providing a direction for the next study. Front Neurosci. 2022 Sep 20;16:940343. doi: 10.3389/fnins.2022.940343. eCollection 2022. Neuropathic Pain Pain Relief Review
36314416 The exclusion criteria were (1) the use of acupuncture for cancer pain relief, which contained clinical studies; (2) experiments not studying cancer pain; (3) reviews, publications without full texts, duplicated studies. Integr Cancer Ther. 2022 Jan-Dec;21:15347354221123788. doi: 10.1177/15347354221123788. Cancer Pain Pain Relief Review
36340786 In contrast to acute medications, the acupuncture-treated group showed a lower pain intensity than those treated with acetaminophen, while found that sumatriptan was more effective than acupuncture in relieving headaches in the first 2 h. Among the clinical trials we included, there are plenty of studies confirmed that acupuncture brings better benefits than prophylactic drugs, yet the effect on acute pain relief still need further exploration. Front Neurosci. 2022 Oct 20;16:1022455. doi: 10.3389/fnins.2022.1022455. eCollection 2022. Pain Relief Review
36340786 Based on these findings, we may get a glimpse of the pain relief produced by acupuncture treatment being associated with the altered activation of the high-order brain regions (DMN) and their increased connections with the descending inhibitory system. Front Neurosci. 2022 Oct 20;16:1022455. doi: 10.3389/fnins.2022.1022455. eCollection 2022. Pain Relief Review
36340786 Two studies showed a leading question is whether bilateral alterations of the connectivities within the rFPN have effects on acupuncture pain relief. Front Neurosci. 2022 Oct 20;16:1022455. doi: 10.3389/fnins.2022.1022455. eCollection 2022. Pain Relief Review
36408345 Multidimensional Pain Modulation by Acupuncture Analgesia: The Reward Effect of Acupuncture on Pain Relief Evid Based Complement Alternat Med. 2022 Nov 10;2022:3759181. doi: 10.1155/2022/3759181. eCollection 2022. Pain Relief Review
36408345 A recent study has also highlighted the importance of cortical mechanisms, reporting that the effect of electroacupuncture on pain relief may be achieved through cortical loop regulation mediated by cannabinoid receptor 1. Evid Based Complement Alternat Med. 2022 Nov 10;2022:3759181. doi: 10.1155/2022/3759181. eCollection 2022. Pain Relief Review
36408345 Therefore, if we can study the reward effect of acupuncture on pain relief (negative enhancement of pain) or the regulating effect of the brain reward system on acupuncture analgesia, we will innovate the study concept of acupuncture analgesia and provide new ideas and perspectives for further elucidating the mechanism of acupuncture analgesia. Evid Based Complement Alternat Med. 2022 Nov 10;2022:3759181. doi: 10.1155/2022/3759181. eCollection 2022. Pain Relief Review
36482655 Besides, several hypotheses have been put out that stress the role of acupuncture in pain relief, such as its ability to induce an analgesic effect on the hypothalamic-pituitary-adrenal axis and the endogenous opioid system. Medicine (Baltimore). 2022 Dec 2;101(48):e31891. doi: 10.1097/MD.0000000000031891. Analgesic Effect Pain Relief Review
36570846 Acupuncture analgesia is well-known for its efficacy, and pain relief by acupuncture is accompanied by ANS activity regulation. Front Neurosci. 2022 Dec 8;16:1038945. doi: 10.3389/fnins.2022.1038945. eCollection 2022. Pain Relief Review
36570846 Strengthening the connection between the AMG and the related nuclei in the PFC, hypothalamus, PAG, and VLM has been proposed to be the potential mechanism underlying the relief of pain-associated emotion by acupuncture, together with other therapeutic effects. Front Neurosci. 2022 Dec 8;16:1038945. doi: 10.3389/fnins.2022.1038945. eCollection 2022. Pain Relief Mood Review
36590302 Also, acupuncture could modulate brain regions involved in limbic system to achieve pain relief or relieve negative effects (Shi et al.,), such as hippocampus, parahippocampal gyrus, and anterior cingulate gyrus (Hui et al.,). Front Neurosci. 2022 Dec 14;16:1049887. doi: 10.3389/fnins.2022.1049887. eCollection 2022. Pain Relief Review
36698826 Clinical efficacy of acupuncture for pain relief from renal colic: A meta-analysis and trial sequence analysis Front Med (Lausanne). 2023 Jan 9;9:1100014. doi: 10.3389/fmed.2022.1100014. eCollection 2022. Pain Relief Kidney Review
36698826 Recent meta-analyses have demonstrated the effectiveness of acupuncture for acute pain relief in patients with musculoskeletal disorders. Front Med (Lausanne). 2023 Jan 9;9:1100014. doi: 10.3389/fmed.2022.1100014. eCollection 2022. Pain Relief Review
36698826 Merged results of the eight studies with available information for analysis showed a faster pain relief in the acupuncture group compared with the control group (MD = −10.74 min, 95% CI: −12.65 to −8.82, p < 0.00001, I2 = 87%, 839 patients) (Figure 7). Front Med (Lausanne). 2023 Jan 9;9:1100014. doi: 10.3389/fmed.2022.1100014. eCollection 2022. Pain Relief Review
36698826 Forest plot comparing the time to pain relief between acupuncture and control groups. Front Med (Lausanne). 2023 Jan 9;9:1100014. doi: 10.3389/fmed.2022.1100014. eCollection 2022. Pain Relief Review
36698826 Trial sequential analysis of the robustness of evidence supporting the difference in time to pain relief between the acupuncture and control groups. Front Med (Lausanne). 2023 Jan 9;9:1100014. doi: 10.3389/fmed.2022.1100014. eCollection 2022. Pain Relief Review
36698826 The current meta-analysis demonstrated that the onset of pain relief with acupuncture was faster than that associated with conventional analgesics (i.e., MD = −10.74 min). Front Med (Lausanne). 2023 Jan 9;9:1100014. doi: 10.3389/fmed.2022.1100014. eCollection 2022. Pain Relief Review
36698826 Our finding was consistent with that of a previous paired meta-analysis that supported the prompt analgesic effect of acupuncture for acute pain relief in a variety of settings with an onset ranging from 15 to 30 min. Front Med (Lausanne). 2023 Jan 9;9:1100014. doi: 10.3389/fmed.2022.1100014. eCollection 2022. Analgesic Effect Pain Relief Review
36698826 A previous randomized double-blind clinical trial also showed that acupuncture provided faster pain relief compared to ibuprofen in patients with acute toothache. Front Med (Lausanne). 2023 Jan 9;9:1100014. doi: 10.3389/fmed.2022.1100014. eCollection 2022. Pain Relief Review
36698826 Objective outcome indicators, such as time to complete pain relief, episodes of renal colic during treatment and adverse effects as well as circulating prostaglandin E2 concentration, may be included in future studies to provide more accurate information for elucidating the beneficial effects of acupuncture in this clinical setting. Front Med (Lausanne). 2023 Jan 9;9:1100014. doi: 10.3389/fmed.2022.1100014. eCollection 2022. Pain Relief Adverse Reactions Kidney Circulation Review
36704010 The pairwise meta-analysis results revealed that the efficacy of all acupuncture-related treatments for pain relief related to PHN was significantly better than antiepileptics. Front Neurosci. 2023 Jan 10;16:1056102. doi: 10.3389/fnins.2022.1056102. eCollection 2022. Pain Relief Review
36704010 The network meta-analysis results showed that pricking and cupping plus antiepileptics were the most effective treatment, followed by electroacupuncture (EA) plus antiepileptics for pain relief in patients with PHN. Front Neurosci. 2023 Jan 10;16:1056102. doi: 10.3389/fnins.2022.1056102. eCollection 2022. Pain Relief Review
36704010 Pricking and cupping plus antiepileptics, are the most effective acupuncture-related techniques for pain relief, while EA plus antiepileptics is the best acupuncture-related technique for improving PHN-related insomnia and depression symptoms. Front Neurosci. 2023 Jan 10;16:1056102. doi: 10.3389/fnins.2022.1056102. eCollection 2022. Pain Relief Insomnia Depression Review
36704010 Additionally, the other eight methods have moderate pain relief effects, although it is difficult to determine which single acupuncture treatment is the best, considering the complexity of the results. Front Neurosci. 2023 Jan 10;16:1056102. doi: 10.3389/fnins.2022.1056102. eCollection 2022. Pain Relief Review
36704010 (1) Acupuncture modulates the interaction between nociceptive receptors and the inflammatory immune response, inhibiting the release of inflammatory cytokines, lipids, prostaglandin E2, 5-hydroxytryptamine, histamine, and nerve growth factor by immune cells, inhibiting peripheral receptor nociceptor sensitization and transient receptor potential cation channel subfamily V member 1 phosphorylation, alleviating peripheral sensitization resulting in pain relief. Front Neurosci. 2023 Jan 10;16:1056102. doi: 10.3389/fnins.2022.1056102. eCollection 2022. Immunity Pain Relief Review
36704010 Therefore, we do not recommend antiepileptics for patients with PHN comorbid with neurological diseases or older people, although combined therapy is better than acupuncture alone for pain relief. Front Neurosci. 2023 Jan 10;16:1056102. doi: 10.3389/fnins.2022.1056102. eCollection 2022. Pain Relief Review
36824638 Some people find some pain relief through acupuncture, infiltration trigger points, massage, psychotherapy, relaxation exercises, music-based interventions, meditation and hypnosis. Acta Clin Croat. 2022 Sep;61(Suppl 2):103-108. doi: 10.20471/acc.2022.61.s2.13. Pain Relief Review
36845439 For patients with sciatica, acupuncture has been recommended as an effective method for pain relief, while there is currently a lack of sufficient evidence to support its efficacy and safety. Front Neurosci. 2023 Feb 9;17:1097830. doi: 10.3389/fnins.2023.1097830. eCollection 2023. Pain Relief Review
36845439 According to the efficacy and safety of acupuncture for pain relief, patients with sciatica often give consent to undergo acupuncture treatment in China. Front Neurosci. 2023 Feb 9;17:1097830. doi: 10.3389/fnins.2023.1097830. eCollection 2023. Pain Relief Review
36845439 However, we found that there was very low-certainty evidence showing that acupuncture offered greater pain relief than MT by reducing the VAS score and increasing the pain threshold, which was mainly related to the weakness of the study design and methodology in the included studies. Front Neurosci. 2023 Feb 9;17:1097830. doi: 10.3389/fnins.2023.1097830. eCollection 2023. Pain Relief Review
36950225 In the trial by Almeida et al., acupuncture achieved the similar pain relief than dipyrone. Jpn Dent Sci Rev. 2023 Dec;59:114-128. doi: 10.1016/j.jdsr.2023.02.005. Epub 2023 Mar 10. Pain Relief Review
36950556 And electroacupuncture produced greater pain relief. Front Oncol. 2023 Mar 6;13:1077961. doi: 10.3389/fonc.2023.1077961. eCollection 2023. Pain Relief Review
37025199 proposed that acupuncture for pain relief was different from, but obviously influenced by the placebo effect, and the placebo effect was different between the real point and the fake point. Front Neurol. 2023 Mar 21;14:1151421. doi: 10.3389/fneur.2023.1151421. eCollection 2023. Pain Relief Review
37256179 The definition of acupuncture and intervention types is displayed in Table 3 ; (3) Primary outcomes included pain relief rate, VAS scores, Pain Numerical Rating Scale (NRS) score, Analgesic efficacy, EORTC QLQ-C30 scores, etc. Front Oncol. 2023 May 15;13:1169458. doi: 10.3389/fonc.2023.1169458. eCollection 2023. Pain Relief Review
37289799 Moreover, given that physical pain commonly occurs after earthquake exposure and is associated with poor long-term physical function and that acupuncture has been found to promote pain relief based on high-quality evidence, acupuncture research on earthquake survivors with physical pain and psychological symptoms may also be an attractive area for research. PLoS One. 2023 Jun 8;18(6):e0286671. doi: 10.1371/journal.pone.0286671. eCollection 2023. Pain Relief Review
37297763 Acupuncture treatment (AT) is an effective treatment for pain relief; however, there are few systematic reviews that have reported on the effectiveness of AT for hip pain. Healthcare (Basel). 2023 Jun 1;11(11):1624. doi: 10.3390/healthcare11111624. Pain Relief Review
37297763 Acupuncture is known to be effective for pain relief. Healthcare (Basel). 2023 Jun 1;11(11):1624. doi: 10.3390/healthcare11111624. Pain Relief Review
37297763 GB34 and LI4 were also used, and the reason for their use is considered to be because GB34 is a commonly used acupuncture point for musculoskeletal disorders throughout the body, and LI4 is effective for pain relief. Healthcare (Basel). 2023 Jun 1;11(11):1624. doi: 10.3390/healthcare11111624. Pain Relief Review
37332744 Efficacy of acupuncture for pain relief in patients receiving extracorporeal shock wave lithotripsy: a meta-analysis of randomized controlled studies Front Med (Lausanne). 2023 Jun 2;10:1114485. doi: 10.3389/fmed.2023.1114485. eCollection 2023. Pain Relief Review
37332744 This meta-analysis aimed at investigating the efficacy of acupuncture for pain relief in patients receiving extracorporeal shock wave lithotripsy (ESWL). Front Med (Lausanne). 2023 Jun 2;10:1114485. doi: 10.3389/fmed.2023.1114485. eCollection 2023. Pain Relief Review
37332744 The results of this meta-analysis showed that the use of acupuncture in patients receiving ESWL was associated with a higher pain relief rate and a lower risk of adverse events, suggesting feasibility of its use in this clinical setting. Front Med (Lausanne). 2023 Jun 2;10:1114485. doi: 10.3389/fmed.2023.1114485. eCollection 2023. Pain Relief Review
37332744 Acupuncture has long been used as a mode of analgesia that improves lower urinary tract symptoms through inducing ureteral smooth muscle relaxation, thereby achieving renal colic pain relief. Front Med (Lausanne). 2023 Jun 2;10:1114485. doi: 10.3389/fmed.2023.1114485. eCollection 2023. Pain Relief Kidney Review
37332744 Literature search was performed to identify eligible randomized controlled trials (RCTs) investigating the effectiveness of acupuncture for pain relief in patients receiving ESWL. Front Med (Lausanne). 2023 Jun 2;10:1114485. doi: 10.3389/fmed.2023.1114485. eCollection 2023. Pain Relief Review
37332744 The current meta-analysis demonstrated the effectiveness of acupuncture not only during ESWL as reflected by a higher percentage of participants experiencing effective pain relief and a reduced ESWL-related pain severity compared to those in the controls, but also after the procedure when a lower postoperative pain score and a higher stone-free rate were noted despite a lack of significant difference compared to the control group in the latter. Front Med (Lausanne). 2023 Jun 2;10:1114485. doi: 10.3389/fmed.2023.1114485. eCollection 2023. Pain Relief Review
37332744 One recent large-scale systematic review including 23 RCTs and 2,439 participants evaluated the efficacy of complementary therapies (i.e., music, acupuncture, acupressure, TENS, and audiovisual transfer) for pain relief in patients receiving ESWL. Front Med (Lausanne). 2023 Jun 2;10:1114485. doi: 10.3389/fmed.2023.1114485. eCollection 2023. Pain Relief Review
37332744 The main finding of the current meta-analysis was the analgesic efficacy of acupuncture as demonstrated by a higher percentage of participants achieving effective pain relief and a reduced ESWL-related pain severity compared to those in the control groups. Front Med (Lausanne). 2023 Jun 2;10:1114485. doi: 10.3389/fmed.2023.1114485. eCollection 2023. Pain Relief Review
37332744 Five of the included studies used electroacupuncture for pain relief. Front Med (Lausanne). 2023 Jun 2;10:1114485. doi: 10.3389/fmed.2023.1114485. eCollection 2023. Pain Relief Review
37332744 Moreover, the description of a higher incidence of recurrent renal colic as the major adverse event among the recruited individuals in the two studies that enrolled control subjects with no medication may further imply the efficacy of acupuncture for pain relief in patients receiving ESWL. Front Med (Lausanne). 2023 Jun 2;10:1114485. doi: 10.3389/fmed.2023.1114485. eCollection 2023. Pain Relief Kidney Review
37332744 In conclusion, the results of the current meta-analysis and systematic review supported the efficacy of conventional acupuncture and related techniques for pain relief during and after ESWL. Front Med (Lausanne). 2023 Jun 2;10:1114485. doi: 10.3389/fmed.2023.1114485. eCollection 2023. Pain Relief Review
37337608 Therefore, acupuncture therapy has become one of the most commonly used non-pharmacological therapies for PD thanks to the advantages in treating PD, such as precise efficacy and significant pain relief; the latest evidence-based acupuncture guidelines also recommend the use of acupuncture therapy. J Pain Res. 2023 Jun 14;16:2027-2046. doi: 10.2147/JPR.S411923. eCollection 2023. Pain Relief Review
37449100 Moxibustion had better pain relief than acupuncture in osteoarthritis knee patients. Heliyon. 2023 Jul 4;9(7):e17805. doi: 10.1016/j.heliyon.2023.e17805. eCollection 2023 Jul. Pain Relief Review
37449100 However, the studies reporting pain score using VAS (pooled WMD = −0.60; 95% CI: −0.73 to −0.48) and ISOA (Index of Severity of the Osteoarthritis) (pooled WMD = −0.93; 95% CI: −1.43 to −0.42) has revealed a significantly better pain relief in patients undergoing moxibustion compared to acupuncture (Fig. Heliyon. 2023 Jul 4;9(7):e17805. doi: 10.1016/j.heliyon.2023.e17805. eCollection 2023 Jul. Pain Relief Review
37449100 Our review found that moxibustion has significantly more effect than acupuncture in managing knee osteoarthritis, both in terms of pain relief and clinical or therapeutic effective rate. Heliyon. 2023 Jul 4;9(7):e17805. doi: 10.1016/j.heliyon.2023.e17805. eCollection 2023 Jul. Pain Relief Review
37478239 Also, our findings from subgroup analysis indicated that there was no difference for shoulder pain relief between EA and RT, CA and RT, but the sensitivity analysis using a fixed effects model demonstrated that acupuncture was more effective than RT in reducing shoulder pain. Medicine (Baltimore). 2023 Jul 21;102(29):e34266. doi: 10.1097/MD.0000000000034266. Pain Relief Review
37478239 Acupuncture and different interventions may differ in shoulder pain relief of patients with PSSP, however, the result of subgroup analysis indicated that there was no difference between CA or EA and RT in shoulder pain relief. Medicine (Baltimore). 2023 Jul 21;102(29):e34266. doi: 10.1097/MD.0000000000034266. Pain Relief Review
37678839 Electroacupuncture therapy increasing the abundance of GRK2 neuron to restore GRK2 expressions, then inhibiting microglial activation and suppressing neuroinflammation in the spinal cord, thereby promoting inflammatory pain relief. Mol Pain. 2023 Jan-Dec;19:17448069231202882. doi: 10.1177/17448069231202882. Pain Relief Inflammatory Pain Review
37712096 Pain relief induced by repeated acupuncture is often accompanied by improved synaptic plasticity in brain nerves. Front Neurosci. 2023 Aug 30;17:1243231. doi: 10.3389/fnins.2023.1243231. eCollection 2023. Pain Relief Review
37904453 Additionally, this type of acupuncture did not demonstrate pain relief in a randomized controlled trial of thoracotomy. Medicine (Baltimore). 2023 Oct 27;102(43):e35759. doi: 10.1097/MD.0000000000035759. Pain Relief Review
37942632 Criteria for inclusion were as follows: (a) types of studies: only SRs/MAs that based on randomized controlled trials (RCTs) were included; (b) participants: patients with cancer and suffering from pain, regardless of cancer stage and current treatment; (c) types of interventions: acupuncture was an eligible intervention, while comparative intervention could be analgesics or sham acupuncture; (d) types of outcomes: response rate, reduction of pain intensity, onset time of pain relief, duration of pain relief, reduction of analgesic dose, and side effects. Integr Cancer Ther. 2023 Jan-Dec;22:15347354231210288. doi: 10.1177/15347354231210288. Pain Relief Side Effects Review
37942632 The results of these reviews indicated that the pain relief rate in the intervention group (acupuncture plus drug therapy) was significantly higher than that in the control group (drug therapy). Integr Cancer Ther. 2023 Jan-Dec;22:15347354231210288. doi: 10.1177/15347354231210288. Pain Relief Review
37942632 However, acupuncture treatment alone was not superior to drug in improving the pain relief rate. Integr Cancer Ther. 2023 Jan-Dec;22:15347354231210288. doi: 10.1177/15347354231210288. Pain Relief Review
38046583 Effectiveness of acupuncture for pain relief in shoulder-hand syndrome after stroke: a systematic evaluation and Bayesian network meta-analysis Front Neurol. 2023 Nov 17;14:1268626. doi: 10.3389/fneur.2023.1268626. eCollection 2023. Pain Relief Review
38046583 As an alternative therapy for pain relief, acupuncture has certain advantages in alleviating pain caused by SHS after stroke. Front Neurol. 2023 Nov 17;14:1268626. doi: 10.3389/fneur.2023.1268626. eCollection 2023. Pain Relief Review
38046583 This review included 38 studies that reported the pain relief effect of multiple acupuncture methods for post-stroke SHS using the VAS scale. Front Neurol. 2023 Nov 17;14:1268626. doi: 10.3389/fneur.2023.1268626. eCollection 2023. Pain Relief Review
38046583 Network relationship diagram of the VAS pain relief of multiple acupuncture methods for post-stroke SHS (the larger the dot in the figure, the more samples it contains; the thicker the line between two dots, the more documents are compared between the two groups). Front Neurol. 2023 Nov 17;14:1268626. doi: 10.3389/fneur.2023.1268626. eCollection 2023. Pain Relief Review
38046583 Our network meta-analysis found that the top five interventions for improving pain according to the VAS scale are floating needle, rehabilitation + catgut embedding, other multi-needle acupuncture combinations, special needle operation and technique, and acupuncture on non-affected limb, which have a significant effect on pain relief. Front Neurol. 2023 Nov 17;14:1268626. doi: 10.3389/fneur.2023.1268626. eCollection 2023. Pain Relief Review
38046583 Floating needle acupuncture and catgut embedding + rehabilitation show good performance in pain relief, but the sample size of floating needle acupuncture is small. Front Neurol. 2023 Nov 17;14:1268626. doi: 10.3389/fneur.2023.1268626. eCollection 2023. Pain Relief Review
38046583 Most notably, other multi-needle acupuncture combinations and special needle operations and techniques all demonstrate good effects in pain relief and upper limb motor function recovery. Front Neurol. 2023 Nov 17;14:1268626. doi: 10.3389/fneur.2023.1268626. eCollection 2023. Pain Relief Motor Function Review
38046594 To evaluate the efficacy and safety of acupuncture for pain relief in patients diagnosed with diabetic peripheral neuropathy, we conducted a systematic review and meta-analysis. Front Neurol. 2023 Nov 16;14:1281485. doi: 10.3389/fneur.2023.1281485. eCollection 2023. Pain Relief Review
38200908 Electro-acupuncture for irritable bowel syndrome led to decreased activity in the anterior cingulate cortex, offering pain relief, while electro-acupuncture for obesity impacted brain regions associated with dietary inhibition and emotional regulation. Healthcare (Basel). 2023 Dec 19;12(1):2. doi: 10.3390/healthcare12010002. Pain Relief Mood Review
38200908 Our review identified one study that aimed to determine the specific influence of somatosensory input on fibromyalgia pain relief through acupuncture and the related brain circuits. Healthcare (Basel). 2023 Dec 19;12(1):2. doi: 10.3390/healthcare12010002. Pain Relief Review
6660201 It was speculated as one of the reasons for less changes of skin resistance under local anesthesia that sympathetic nervous activity did not occur so much because of pain relief due to local anesthesia. Am J Chin Med. 1983;11(1-4):130-6. doi: 10.1142/S0192415X83000215. Pain Relief Clinic
32188223 OBJECTIVE: To evaluate the effectiveness of acupuncture analgesia (AA) compared with combined spinal-epidural anesthesia (CSEA) for labor pain relief and labor outcomes. J Tradit Chin Med. 2017 Oct;37(5):629-635. Pain Relief Clinic
32188223 CONCLUSION: Both AA and CSEA were effective for labor pain relief, CSEA provided more effective pain relief, while AA was associated with a shorter duration of labor and fewer adverse effects.and each has its advantages and disadvantages. J Tradit Chin Med. 2017 Oct;37(5):629-635. Pain Relief Adverse Reactions Clinic
12859301 BACKGROUND: Acupuncture is used for clinical pain relief but has not been evaluated under clinical anaesthesia. Acta Anaesthesiol Scand. 2003 Aug;47(7):818-22. doi: 10.1034/j.1399-6576.2003.00171.x. Pain Relief Clinic
25158837 Acupuncture for pain relief after total knee arthroplasty: a randomized controlled trial. Reg Anesth Pain Med. 2015 Jan-Feb;40(1):31-6. doi: 10.1097/AAP.0000000000000138. Pain Relief Clinic
10326816 MAIN OUTCOME MEASURES: Patients' self-reports of time until moderate pain, time until medication use, total pain relief, pain half gone, and total pain medication consumption. Arch Otolaryngol Head Neck Surg. 1999 May;125(5):567-72. doi: 10.1001/archotol.125.5.567. Pain Relief Clinic
10326816 There were no significant between-groups differences on total-pain-relief scores or pain-half-gone scores (P>.05). Arch Otolaryngol Head Neck Surg. 1999 May;125(5):567-72. doi: 10.1001/archotol.125.5.567. Pain Relief Clinic
141644 Prolonged relief of pain by brief, intense transcutaneous somatic stimulation. Pain. 1975 Dec;1(4):357-373. doi: 10.1016/0304-3959(75)90073-1. Pain Relief Clinic
141644 Different patterns of the amount and duration of pain relief were observed. Pain. 1975 Dec;1(4):357-373. doi: 10.1016/0304-3959(75)90073-1. Pain Relief Clinic
141644 Possible neural mechanisms that underlie these patterns of pain relief by brief, intense stimulation are discussed. Pain. 1975 Dec;1(4):357-373. doi: 10.1016/0304-3959(75)90073-1. Pain Relief Clinic
11506105 RESULTS: Starting from the recovery room, intradermal acupuncture increased the fraction of patients with good pain relief as compared with the control (P < 0.05). Anesthesiology. 2001 Aug;95(2):349-56. doi: 10.1097/00000542-200108000-00015. Pain Relief Clinic
15777857 Auricular acupuncture for pain relief after total hip arthroplasty - a randomized controlled study. Pain. 2005 Apr;114(3):320-327. doi: 10.1016/j.pain.2004.08.021. Pain Relief Clinic
25926298 CONCLUSIONS: Multipoint TEAS at both proximal and distal points combined with TIVA can significantly decrease intraoperative sufentanil requirements, increase pain relief on postoperative day 1 and improve postoperative recovery of patients during supratentorial tumour resection, with no significant increase of side effects. Acupunct Med. 2015 Aug;33(4):270-6. doi: 10.1136/acupmed-2014-010749. Epub 2015 Apr 29. Pain Relief Side Effects Clinic
27437568 Perioperative Transcutaneous Electrical Acupoint Stimulation for Postoperative Pain Relief Following Laparoscopic Surgery: A Randomized Controlled Trial. Clin J Pain. 2017 Apr;33(4):340-347. doi: 10.1097/AJP.0000000000000400. Pain Relief Clinic
16820123 Pain relief during oocyte retrieval--exploring the role of different frequencies of electro-acupuncture. Reprod Biomed Online. 2006 Jul;13(1):120-5. doi: 10.1016/s1472-6483(10)62025-1. Pain Relief Clinic
25047046 These include a series of elements such as providing the patient with thorough preoperative information and education concerning perioperative care, the use of safe and short-acting anaesthetics and optimal dynamic pain relief with minimal use of opioids, management of PONV, enteral nutrition, early mobilization and use of minimal invasive surgery. Trials. 2014 Jul 21;15:292. doi: 10.1186/1745-6215-15-292. Pain Relief Clinic
25152761 The aim of this study was to develop an improved acupuncture-assisted anesthesia approach in pain relief. Evid Based Complement Alternat Med. 2014;2014:592319. doi: 10.1155/2014/592319. Epub 2014 Jul 23. Pain Relief Clinic
25152761 The Weizhong acupoint is capable of recuperating the urinary bladder from qi transformation and modulating the functioning of lower-jiao qi activity (下焦氣機) as well as producing a quick response pain relief through fluid circulation of qi. Evid Based Complement Alternat Med. 2014;2014:592319. doi: 10.1155/2014/592319. Epub 2014 Jul 23. Pain Relief Circulation Clinic
25152761 The study further supports the analgesia effect of electroacupuncture and it is clear that, despite the use of different acupoints selected in various anatomical areas using a diversity of selection principles, they all are able to fulfill the objective of pain relief. Evid Based Complement Alternat Med. 2014;2014:592319. doi: 10.1155/2014/592319. Epub 2014 Jul 23. Pain Relief Clinic
36034956 In addition, patients with pain relief can get out of bed as early as possible, which plays an irreplaceable role in promoting early postoperative recovery and shortening hospital stay. Evid Based Complement Alternat Med. 2022 Aug 17;2022:3130956. doi: 10.1155/2022/3130956. eCollection 2022. Pain Relief Clinic
23342207 At the present, acupuncture analgesia and acupuncture pain relief are highly emphasized by international medical researchers. Korean J Pain. 2013 Jan;26(1):46-50. doi: 10.3344/kjp.2013.26.1.46. Epub 2013 Jan 4. Pain Relief Clinic
23342207 We prescribed pethidine 1 mg/kg/dose intravenously on demand (in the form of PCA) for pain relief. Korean J Pain. 2013 Jan;26(1):46-50. doi: 10.3344/kjp.2013.26.1.46. Epub 2013 Jan 4. Pain Relief Clinic
23342207 When the PCA demands were compared among these groups, the results showed that the subjects in the control group were more demanding of pain relief than the acupuncture group. Korean J Pain. 2013 Jan;26(1):46-50. doi: 10.3344/kjp.2013.26.1.46. Epub 2013 Jan 4. Pain Relief Clinic
15937559 Auricular Acupuncture for Pain Relief after Ambulatory Knee Arthroscopyxe2x80x94A Pilot Study Evid Based Complement Alternat Med. 2005 Jun;2(2):185-189. doi: 10.1093/ecam/neh097. Epub 2005 May 11. Pain Relief Clinic
15937559 In order to achieve better post-operative pain relief, improve cost-effectiveness and enhance patient satisfaction, an integrative approach combining pharmacological methods and various complementary non-pharmacological analgesic techniques has been recommended. Evid Based Complement Alternat Med. 2005 Jun;2(2):185-189. doi: 10.1093/ecam/neh097. Epub 2005 May 11. Pain Relief Clinic
30356057 At the time of the pre-anaesthetic visit, 12xe2x80x9324xe2x80x89hours prior to surgery, patients in the intervention groups received a standardised treatment with either 12 press needles (ACU; sharp tip; 0.2xe2x80x89mmxe2x80x89xc3x97xe2x80x891.5xe2x80x89mm) or 12 press plasters (APU; blunt knob; both Seirin New Pyonexxc2xae, Seirin Corp., Shizuoka City, Japan) at GV26, a point described to resolve states of sedation and collapse and 6 acupuncture points which have been proposed to relief pain and strengthen the constitution, i.e. Sci Rep. 2018 Oct 24;8(1):15734. doi: 10.1038/s41598-018-33459-y. Pain Relief Sedation Clinic
33488793 Therefore, TEAS might be associated with effective postoperative pain relief and lower analgesic consumption. Exp Ther Med. 2021 Mar;21(3):184. doi: 10.3892/etm.2021.9615. Epub 2021 Jan 7. Pain Relief Clinic
33488793 However, pain relief could also have the potential to benefit immune function by reducing postoperative stress and inhibiting excessive release of inflammatory cytokines. Exp Ther Med. 2021 Mar;21(3):184. doi: 10.3892/etm.2021.9615. Epub 2021 Jan 7. Immunity Pain Relief Clinic
34682857 A recent meta-analysis including 60 randomized control trials reported that manual acupuncture is more effective for menstrual pain relief than no treatment and nonsteroidal anti-inflammatory drugs. J Clin Med. 2021 Oct 15;10(20):4731. doi: 10.3390/jcm10204731. Pain Relief Clinic
34682857 The acupoint selection was based on a recent meta-analysis study that reported that manual acupuncture is more effective for menstrual pain relief and SP6 was the acupoint most frequently used for treating PDM. J Clin Med. 2021 Oct 15;10(20):4731. doi: 10.3390/jcm10204731. Pain Relief Clinic
36749304 Pain relief could be evidenced by the reduction of NRS score in the EA group, compared with the SA group, although both received a conventional analgesic agent during the whole study. Brain Behav. 2023 Mar;13(3):e2913. doi: 10.1002/brb3.2913. Epub 2023 Feb 7. Pain Relief Clinic
29773696 A responder was defined as a study participant withxc2xa0xe2x89xa550%xe2x80x89pain relief using the 100xe2x80x89mm VAS for pain intensity at assessments 9, 10 and 11, and a non-responder as having pain relief ofxc2xa0<50%, respectively (weeks 4, 8 and 12). BMJ Open. 2018 May 17;8(5):e018464. doi: 10.1136/bmjopen-2017-018464. Pain Relief Clinic
29773696 In the ITT analysis (n=39), the proportion of responders, defined as participants withxc2xa0xe2x89xa550%xe2x80x89pain relief on the 100xe2x80x89mm VAS for pain intensity, was 33.3% (n=6) in the EA plus UC group (n=18) andxc2xa09.5% (n=2) in the UC alone group (n=21); the difference between the groups was not statistically significant (p=0.1123; table 2). BMJ Open. 2018 May 17;8(5):e018464. doi: 10.1136/bmjopen-2017-018464. Pain Relief Clinic
29773696 Given the clinical reality that it is difficult to expect functional improvement without relief of pain, our basis for a full-scale RCT seems reasonable. BMJ Open. 2018 May 17;8(5):e018464. doi: 10.1136/bmjopen-2017-018464. Pain Relief Clinic
22968837 Secondary outcome measurements included pain relief and reduced disability level. Eur J Pain. 2013 Feb;17(2):279-89. doi: 10.1002/j.1532-2149.2012.00215.x. Epub 2012 Sep 11. Pain Relief Mechanism
6122716 This effect of the acupuncture like stimulation procedure may be related to clinically reported actions of acupuncture stimulation, which apart from pain relief include, for example, antagonism of heroin abstinence symptoms. J Neural Transm. 1982;53(2-3):91-100. doi: 10.1007/BF01243400. Pain Relief Mechanism
21749999 All animals having electroacupuncture experienced prolonged analgesia, over 24 h at least, while four out of six dogs treated with butorphanol needed post-surgical ketorolac and tramadol supplementation to their pain relief. Br J Anaesth. 2011 Oct;107(4):612-8. doi: 10.1093/bja/aer199. Epub 2011 Jul 12. Pain Relief Mechanism
17664006 Acupuncture analgesia is a very useful clinical tool for pain relief, which has over 2500-year history in China. Neuropeptides. 2007 Oct;41(5):285-92. doi: 10.1016/j.npep.2007.05.004. Epub 2007 Jul 30. Pain Relief Mechanism
31941349 BACKGROUND: Acupuncture has been clinically recommended as a method of pain relief by the World Health Organization and is widely used by medical doctors. Acupunct Med. 2020 Apr;38(2):101-108. doi: 10.1136/acupmed-2017-011395. Epub 2020 Jan 16. Pain Relief Mechanism
31941349 Acupuncture may serve as an effective alternative treatment for pain relief with few side effects. Acupunct Med. 2020 Apr;38(2):101-108. doi: 10.1136/acupmed-2017-011395. Epub 2020 Jan 16. Pain Relief Side Effects Mechanism
35138669 Our findings represent an important step forward in clarifying the mechanisms of pain relief afforded by acupuncture treatment. Eur J Pain. 2022 May;26(5):991-1005. doi: 10.1002/ejp.1923. Epub 2022 Feb 17. Pain Relief Mechanism
19607689 The analgesic ladder for cancer-related pain provided by the WHO involves progressing from non-opioid (e.g., acetaminophen, ibuprofen), weak opioid (e.g., codeine), and finally to strong opioid (e.g., morphine, fentanyl) intervention for pain relief. J Exp Clin Cancer Res. 2009 Jul 16;28(1):102. doi: 10.1186/1756-9966-28-102. Pain Relief Mechanism
19607689 But, unfortunately, opioid analgesics often produce poor pain relief against neuropathic cancer pain and also induce adverse side effects such as hormone (e.g., ACTH, cortisol, LH and testosterone) secretion, neurotransmitter (e.g., nicotine, adenosine, GABA and cholecystokinine) release, feeding, gastrointestinal motility, and respiratory activity. J Exp Clin Cancer Res. 2009 Jul 16;28(1):102. doi: 10.1186/1756-9966-28-102. Cancer Pain Pain Relief Side Effects Mechanism
37548586 The possible central analgesic mechanisms of EA for pain relief in CSR will be systematically explored. Brain Behav. 2023 Oct;13(10):e3177. doi: 10.1002/brb3.3177. Epub 2023 Aug 7. Pain Relief Mechanism
21796340 Thus, it appears that acupuncture may play the role as the trigger making possible pain relief. Pflugers Arch. 2011 Oct;462(4):587-97. doi: 10.1007/s00424-011-0993-7. Epub 2011 Jul 28. Pain Relief Mechanism
22524543 Summary: Acupuncture mechanism can be exploited to provide extremely long-lasting pain relief. Mol Pain. 2012 Apr 23;8:28. doi: 10.1186/1744-8069-8-28. Pain Relief Mechanism
38026466 Acupuncture shows rapid relief of pain and numbness, whole body regulation, and minor adverse reactions, generally using local acupoints as the main points, and distant acupoints as adjunct points. J Pain Res. 2023 Nov 20;16:3945-3960. doi: 10.2147/JPR.S419927. eCollection 2023. Pain Relief Adverse Reactions Mechanism
27978835 However, the number of acupuncture treatment sessions required for effective pain relief is unclear. BMC Complement Altern Med. 2016 Dec 15;16(1):517. doi: 10.1186/s12906-016-1508-z. Pain Relief Mechanism
27978835 In this study, no significant changes were observed in the PWL during the first three sessions of EA intervention, meaning no remarkable pain relief at that time, but a marked increase of the pain threshold was observed after four sessions of EA intervention, presenting a time-dependent pain relief thereafter. BMC Complement Altern Med. 2016 Dec 15;16(1):517. doi: 10.1186/s12906-016-1508-z. Pain Relief Mechanism
34646326 Acupuncture is widely used to alleviate visceral pain in China, owing to its ability to provide pain relief with few side effects such as addictiveness. Evid Based Complement Alternat Med. 2021 Oct 4;2021:5561999. doi: 10.1155/2021/5561999. eCollection 2021. Visceral Pain Pain Relief Side Effects Mechanism
31447579 Limited evidence to date suggests that acupuncture offers pain relief in patients with SCD and in humanized HbSS-BERK (BERK) transgenic mice with SCD. J Pain Res. 2019 Aug 1;12:2419-2426. doi: 10.2147/JPR.S210196. eCollection 2019. Pain Relief Mechanism
34472492 Acupuncture is a non-pharmacological pain relief therapy derived from traditional Chinese medicine and is gaining popularity in many countries (Deng and Mao, 2019). Neural Regen Res. 2022 Apr;17(4):905-910. doi: 10.4103/1673-5374.322477. Pain Relief Mechanism
24803946 Compared to MA, EA is more effective in pain relief in both humans and animal models, and TAES has been shown to be as effective as EA in analgesia. Evid Based Complement Alternat Med. 2014;2014:431580. doi: 10.1155/2014/431580. Epub 2014 Apr 3. Pain Relief Mechanism
34675986 For instance, an experimental study showed that in patients with chronic back pain, applying acute noxious thermal stimuli to the skin of lower back induced pain relief. Evid Based Complement Alternat Med. 2021 Oct 12;2021:5528780. doi: 10.1155/2021/5528780. eCollection 2021. Pain Relief Mechanism
34675986 Given that MA is being performed flexibly in clinical practice by adjusting the parameters including the needling frequency, depth, and amplitude according to the patient's response, we propose the practice of gentle MA for patients with lower acupuncture tolerance to activate A-fiber for relieving pain, while a strong MA can be performed to activate C-fiber for effective pain relief in patients with higher acupuncture tolerance. Evid Based Complement Alternat Med. 2021 Oct 12;2021:5528780. doi: 10.1155/2021/5528780. eCollection 2021. Pain Relief Mechanism
34675986 Strong MA activates more C-fibers that results in higher pain relief than gentle MA. Evid Based Complement Alternat Med. 2021 Oct 12;2021:5528780. doi: 10.1155/2021/5528780. eCollection 2021. Pain Relief Mechanism
28299842 TENS is a widely accepted method of pain relief. Stem Cells. 2017 May;35(5):1303-1315. doi: 10.1002/stem.2613. Pain Relief Mechanism
32021397 It is well known that acupuncture, a non-pharmacological treatment, has been used worldwide for pain relief as one of the complementary treatments. J Pain Res. 2020 Jan 13;13:75-86. doi: 10.2147/JPR.S225431. eCollection 2020. Pain Relief Mechanism
25206591 Thus, it may be reasonable to conjecture that repeated EA stimulation-induced pain relief may result from favorable regulation of hypothalamic neuronal plasticity and changes in hormone and neurotransmitter levels. Neural Regen Res. 2013 Jan 25;8(3):218-25. doi: 10.3969/j.issn.1673-5374.2013.03.003. Pain Relief Mechanism
25206591 These results reveal that repeated EA intervention-induced pain relief is accompanied with enhanced hypothalamic PVN neural synaptic plasticity, including narrowing of the synaptic cleft and increases in postsynaptic density size, active zone length and interface curvature, which favors release of neurotransmitters and their binding to cell membrane receptors, resulting in an increase in synaptic signal transmission efficiency in the PVN. Neural Regen Res. 2013 Jan 25;8(3):218-25. doi: 10.3969/j.issn.1673-5374.2013.03.003. Pain Relief Mechanism
25206591 It is possible that repeated EA intervention promotes the storage of pain-relief information in the brain, which is consolidated gradually after multiple treatments, resulting in the establishment of the cumulative analgesic effect. Neural Regen Res. 2013 Jan 25;8(3):218-25. doi: 10.3969/j.issn.1673-5374.2013.03.003. Analgesic Effect Pain Relief Mechanism
31775332 Acupuncture is a traditional and effective method for pain relief with few side effects. Int J Mol Sci. 2019 Nov 25;20(23):5917. doi: 10.3390/ijms20235917. Pain Relief Side Effects Mechanism
31775332 Electroacupuncture (EA) combines traditional manual acupuncture with modern electrotherapy and has become a convenient method for pain relief in wide varieties of pain conditions. Int J Mol Sci. 2019 Nov 25;20(23):5917. doi: 10.3390/ijms20235917. Pain Relief Mechanism
28600329 Acupuncture therapy has been lauded as a promising alternative approach for postoperative pain relief. Acupunct Med. 2017 Aug;35(4):276-283. doi: 10.1136/acupmed-2016-011177. Epub 2017 Jun 9. Pain Relief Mechanism
28600329 Regarding the mechanisms of acupuncture for postoperative pain relief, it appears that central endorphin, supraspinal serotonergic and noradrenergic descending projection systems, spinal γ-aminobutyric acid (GABA), and opioid neurotransmitters are involved. Acupunct Med. 2017 Aug;35(4):276-283. doi: 10.1136/acupmed-2016-011177. Epub 2017 Jun 9. Pain Relief Mechanism
37143500 ST36 acupuncture is used for pain relief and immunity, such as suppression of IgE and the effect of Th1/Th2 regulation, while CV12 is the mother blood of the stomach, which is a specific acupuncture point where the energy of the intestines gathers. Front Vet Sci. 2023 Apr 18;10:1153903. doi: 10.3389/fvets.2023.1153903. eCollection 2023. Immunity Pain Relief Mechanism
37143500 We speculate that the combined treatment of EA and LA is helpful in pain relief and nerve regeneration, and induces changes in the intestinal microbiome. Front Vet Sci. 2023 Apr 18;10:1153903. doi: 10.3389/fvets.2023.1153903. eCollection 2023. Pain Relief Mechanism
37143500 In conclusion, the present study provides evidence that the combined treatment of EA and LA helps in pain relief and nerve regeneration and is effective in changing the intestinal microbiome. Front Vet Sci. 2023 Apr 18;10:1153903. doi: 10.3389/fvets.2023.1153903. eCollection 2023. Pain Relief Mechanism
22369266 Acupuncture is particularly useful for pain relief, however, little is understood about its biological basis. Chin Med. 2012 Feb 27;7:3. doi: 10.1186/1749-8546-7-3. Pain Relief Mechanism
20981331 Although it is well known that acupuncture has beneficial effects on a variety of medical conditions especially in pain relief, nausea, and vomiting, it remains controversial whether it has positive impact on the female reproduction. Evid Based Complement Alternat Med. 2011;2011:606514. doi: 10.1155/2011/606514. Epub 2010 Sep 30. Pain Relief Nausea and Vomiting Mechanism
20981331 AC has been used for a variety of medical conditions in both adults and children: pain relief, nausea and vomiting, drug addiction, stroke rehabilitation, depression, irritable bowel syndrome, and asthma, to name a few. Evid Based Complement Alternat Med. 2011;2011:606514. doi: 10.1155/2011/606514. Epub 2010 Sep 30. Pain Relief Nausea and Vomiting Depression Mechanism
20981331 Some investigations have already demonstrated that AC had positive effects in anovulatory subfertility, male subfertility, pain relief during oocyte retrieval, IVF implantation rates, and the quality of life of patients undergoing IVF. Evid Based Complement Alternat Med. 2011;2011:606514. doi: 10.1155/2011/606514. Epub 2010 Sep 30. Pain Relief Mechanism
35003293 Multiple treatment methods for OA have been performed, including oral intake of nonsteroidal anti-inflammatory drugs (NSAIDs) and glucosamine, which could only achieve the goal of pain relief; however, they are insufficient to prevent or cure patients with OA. Evid Based Complement Alternat Med. 2021 Dec 31;2021:2470182. doi: 10.1155/2021/2470182. eCollection 2021. Pain Relief Mechanism
35003293 However, some reports have manifested that pain relief and other functions of acupuncture are likely attributed to patients' greater expectations for these effects. Evid Based Complement Alternat Med. 2021 Dec 31;2021:2470182. doi: 10.1155/2021/2470182. eCollection 2021. Pain Relief Mechanism
35069759 Our previous studies provided evidence that needling techniques could affect the pain-relief effect of SP6 for PD via different pathways. Evid Based Complement Alternat Med. 2022 Jan 13;2022:4571981. doi: 10.1155/2022/4571981. eCollection 2022. Pain Relief Mechanism
35069759 To further address whether pain-relief induced by TN was dependent on the activation of the eotaxin/CCR3 axis, we injected CCR3 antagonist SB328437 and agonist CCL11. Evid Based Complement Alternat Med. 2022 Jan 13;2022:4571981. doi: 10.1155/2022/4571981. eCollection 2022. Pain Relief Mechanism
35069759 This study reported a preferable effect of acupuncture at SP6 with TN on pain relief in CCD rats, which was partly achieved by weakening EOS-MC activation and HIS release via inactivation of eotaxin and CCR3. Evid Based Complement Alternat Med. 2022 Jan 13;2022:4571981. doi: 10.1155/2022/4571981. eCollection 2022. Pain Relief Mechanism
25657670 Thus, repeated electroacupuncture-induced pain relief may involve modulation of hippocampal neuronal plasticity by various hormones and neurotransmitters. Neural Regen Res. 2012 Jun 25;7(18):1378-85. doi: 10.3969/j.issn.1673-5374.2012.18.003. Pain Relief Mechanism
25657670 These results suggest that repeated electroacupuncture-induced pain relief is accompanied by improvement of hippocampal neural synaptic plasticity. Neural Regen Res. 2012 Jun 25;7(18):1378-85. doi: 10.3969/j.issn.1673-5374.2012.18.003. Pain Relief Mechanism
25657670 It is possible that electroacupuncture intervention induces synaptic changes associated with pain-relief which are gradually consolidated with repeated treatment, eventually establishing the observed cumulative analgesic effect. Neural Regen Res. 2012 Jun 25;7(18):1378-85. doi: 10.3969/j.issn.1673-5374.2012.18.003. Analgesic Effect Pain Relief Mechanism
23097675 Due to previous lack of an ideal experimental animal model suitable for acupuncture research which simulates the human model of chronic visceral hypersensitivity, the mechanism of EA treatment on pain relief in IBS remained unclear. Evid Based Complement Alternat Med. 2012;2012:483123. doi: 10.1155/2012/483123. Epub 2012 Oct 11. Pain Relief Mechanism
23097675 In the application of this model in our study, we developed a methodology to assess the effect of different number of times of acupuncture being applied to the same animal which was awake and elucidate its potential mechanism of EA treatment on pain relief in model of visceral hypersensitivity in the mouse. Evid Based Complement Alternat Med. 2012;2012:483123. doi: 10.1155/2012/483123. Epub 2012 Oct 11. Pain Relief Mechanism
23097675 Acupuncture and EA are widely used in pain relief in clinic and in relieving inflammation-induced hypersensitivity in rat models. Evid Based Complement Alternat Med. 2012;2012:483123. doi: 10.1155/2012/483123. Epub 2012 Oct 11. Pain Relief Mechanism
32042305 However, only half patients with CIBP gain temporary pain relief from conventional analgesics, and new and better therapies for CIBP alleviation with few adverse effects are urgently required. Chin Med. 2020 Feb 4;15:13. doi: 10.1186/s13020-020-0289-y. eCollection 2020. Pain Relief Adverse Reactions Mechanism
32042305 WAA has been widely accepted for its ease of use and its remarkable effect in pain relief. Chin Med. 2020 Feb 4;15:13. doi: 10.1186/s13020-020-0289-y. eCollection 2020. Pain Relief Mechanism
27411565 Despite their universal administration for pain relief in osteoarthritis patients, the long term use of NSAIDs is controversial due to the gastrointestinal disorders and cardiovascular events related to their safety profile. BMC Complement Altern Med. 2016 Jul 13;16:212. doi: 10.1186/s12906-016-1204-z. Cardiovascular Pain Relief Mechanism
21799685 Acupuncture can benefit patients with knee osteoarthritis by providing pain relief, improving joint function and serving as an effective complement to standard care. Evid Based Complement Alternat Med. 2011;2011:619650. doi: 10.1093/ecam/neq016. Epub 2011 Jan 9. Pain Relief Mechanism
21799685 There are reports that acupuncture can benefit patients with knee osteoarthritis by providing pain relief, improving joint function and serving as an effective complement to standard care. Evid Based Complement Alternat Med. 2011;2011:619650. doi: 10.1093/ecam/neq016. Epub 2011 Jan 9. Pain Relief Mechanism
26770252 Another study hypothesized that attenuation of p-ERK1/2 overactivity in the ACC represented a potentially valuable therapeutic strategy for the relief of pain-induced anxiety. Evid Based Complement Alternat Med. 2015;2015:235491. doi: 10.1155/2015/235491. Epub 2015 Dec 3. Pain Relief Anxiety Mechanism
29311503 Early-on EA treatment provided significant pain relief and joint structure preservation in KOA rats. Exp Anim. 2018 May 10;67(2):271-280. doi: 10.1538/expanim.17-0142. Epub 2018 Jan 1. Pain Relief Mechanism
22553490 Acupuncture has a history of 3000 years in China and is increasingly used throughout the world especially in the UK, US, Australia and Japan, for pain relief and a variety of disorders, including subfertility. Spermatogenesis. 2012 Jan 1;2(1):53-62. doi: 10.4161/spmg.19282. Pain Relief Mechanism
22553490 It is an effective alternative for pain relief during oocyte retrieval. Spermatogenesis. 2012 Jan 1;2(1):53-62. doi: 10.4161/spmg.19282. Pain Relief Mechanism
25624811 Acupuncture, in particular electro-acupuncture, has increasingly been used as a complementary therapy for pain relief and stroke rehabilitation in both Asian and western countries. Neural Regen Res. 2012 Aug 25;7(24):1859-65. doi: 10.3969/j.issn.1673-5374.2012.24.003. Pain Relief Mechanism
36116306 This study was conducted to evaluate the effect of supporting pain relief and bone healing of electroacupuncture on patients after intramedullary nailing for tibial fractures, and to monitor the undesirable effects of the treatment regimen. Int J Surg Case Rep. 2022 Oct;99:107600. doi: 10.1016/j.ijscr.2022.107600. Epub 2022 Sep 7. Pain Relief Mechanism